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All Journal Berkala Ilmiah Pendidikan Biologi (BioEdu) Jurnal Abdi: Media Pengabdian Kepada Masyarakat BIOTROPIC
Erlix Rakhmad Purnama
Universitas Negeri Surabaya
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Languange, Linguistic, Communication & Media Social Sciences Other

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Journal : BIOTROPIC

 1 
Pemanfaatan Daun Kelor (Moringa oleifera) Terhadap Pemulihan Struktur Pankreas Mencit Diabetik Wanodya Ayu Chandradevi; Muhammad Avesina; Dwi Puspita Anggriyawanti; Erlix Rakhmad Purnama
Biotropic : The Journal of Tropical Biology Vol. 2 No. 2 (2018): Biotropic, Volume 2, Nomor 2, 2018
Publisher : Program Studi Biologi, Fakultas Sains dan Teknologi, Universitas Islam Negeri Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/biotropic.2018.2.2.85-92

Abstract

Moringa oleifera tergolong mudah dijumpai di Indonesia dan mengandung senyawa quercetin yang termasuk dalam jenis flavonoid, dimana senyawa ini berperan sebagai agen hipoglikemik. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak Moringa oleifera terhadap kadar glukosa dan histopatologi pankreas mencit hiperglikemia. Metode yang digunakan pada penelitian ini yaitu ekstraksi daun Moringa oleifera dengan konsentrasi 42 mg/kgBB, 70 mg/kgBB, dan 98 mg/kgBB, lalu penginduksian aloksan secara intraperitoneal, pengaplikasian ekstrak Moringa oleifera, pengambilan organ pankreas dan pembuatan histologi organ pankreas. Hasil penelitian menunjukkan bahwa Pemberian ekstrak Moringa oleifera berpengaruh pada penurunan kadar glukosa dan penambahan diameter pulau Langerhans pankreas mencit diabetes. Konsentrasi ekstrak yang paling berpengaruh adalah 98 mg/kgBB. Maka dapat diambil simpulan bahwa ekstrak Moringa oleifera pada konsentrasi berpotensi sebagai antihiperglikemia.
Potensi Ekstrak Daun Bandotan (Ageratum conyzoides L.) Sebagai Spray Untuk Pemulihan Luka Mencit Diabetik Yang Terinfeksi Staphylococcus aureus Erra Ericha Safani; Wanodya Ayu Chandradevi Kunharjito; Alfiyan Lestari; Erlix Rakhmad Purnama
Biotropic : The Journal of Tropical Biology Vol. 3 No. 1 (2019): Biotropic, Volume 3, Nomor 1, 2019
Publisher : Program Studi Biologi, Fakultas Sains dan Teknologi, Universitas Islam Negeri Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/biotropic.2019.3.1.68-78

Abstract

Ageratum conyzoides L. leaf has the main compound of flavonoids and alkaloids that contribute to accelerate the healing process of diabetic ulcers with Staphylococcus aureus infection that can affect the quality of life of patients. This study aims to test the leaves of Ageratum conyzoides L. on the recovery of diabetic ulcers of mice infected with Staphylococcus aureus. The method used is the extraction of Ageratum conyzoides L leaves as the material of spray 15%, induction of diabetic compound (Alloxan monohydrate), length wound (1cm) and bacterial infections, and spray application with 1 times daily frequency, 2 times daily, 3 times a day for 9 days. The results showed that the lenght of wounds in group A, B, C, D, and E were 0,5; 0,8; 0,4; 0,2; 0,0. The administration of Ageratum conyzoides L. spray which has active flavonoide substances, alkaloid substance, and saponin substances has an effect on decreased length of diabetic wounds and restoration of dermis tissue structure (increases epithelial cells proliferation, initiates fibroblast cells, and stimulates type 1 collagen). Spray treatment 3 times a day (group E) was more influential than the other treatments, which experienced wound closure in 9 days. Thus, Ageratum conyzoides L. leaf spray is potential for therapy of diabetic ulcers infected with Staphylococcus aureus.
Co-Authors Alfiyan Lestari Dwi Puspita Anggriyawanti Erra Ericha Safani Indiarti Dwi Fina M. Ongky Muji Handoyo Maulana, Dimas Avian Mirwa Adiprahara Anggarani Mirwa Anggarani Muhammad Avesina Nur Ducha Raharjo, Raharjo Raya Sulistyowati Ricky Eka Putra Sabila Maghfiroh Tri Sudarwanto Wanodya Ayu Chandradevi Wanodya Ayu Chandradevi Kunharjito Yuliani, Yuliani