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The Validity of Student Worksheets Based on Problem-Based Learning in Human Blood Type System Sub Materials to Train Critical Thinking Skill for Senior High School Students Sabila Maghfiroh; Nur Ducha; Erlix Rakhmad Purnama
Berkala Ilmiah Pendidikan Biologi (BioEdu) Vol 9 No 3 (2020)
Publisher : Program Studi Pendidikan Biologi, FMIPA, Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/bioedu.v9n3.p458-465

Abstract

Critical thinking skill is one of the competencies students must master to be able to confront the challenges of 21st-century education. The government seeks to compile the 2013 curriculum with learner-centered learning that is relevant to daily life. Learning that is relevant in daily life, one of which is the learning of Biology in the sub materials of Human Blood Type System. One alternative that can be used to facilitate students in developing their critical thinking skills is by providing them teaching materials forms students worksheets based on Problem Based Learning (PBL). This study aimed to produce PBL-based Students Worksheets to train students’ critical thinking skills in the sub material of Human Blood type System based on the feasibility of presentation, content, and language. This study used the 4D model there were define, design, develop, disseminate. The stages carried out only up until the development stage. The validity of Students Worksheets was determined based on the results of the validation by three validators using the validation sheet instrument. Aspects of validity rated include aspects of presentation, content, language, worksheets characteristics to train critical thinking skills, and PBL-oriented worksheets characteristics. The results showed that the PBL-based worksheets in this study obtained a validity score of 3.95 with a very valid category. Based on the results of the validity, it can be concluded that the developed PBL-based worksheets in this study can be used in the teaching and learning process to train students' critical thinking skills. Keywords: Validation, PBL-based worksheet, human blood type, critical thinking skills.
Uji in Silico Senyawa Phytol Hasil Ekstrak Daun Zodia (Evodiasuaveolens) sebagai Antikanker M. Ongky Muji Handoyo; Yuliani Yuliani; Erlix Rakhmad Purnama
Berkala Ilmiah Pendidikan Biologi (BioEdu) Vol 11 No 2 (2022)
Publisher : Program Studi Pendidikan Biologi, FMIPA, Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/bioedu.v11n2.p368-373

Abstract

Kanker merupakan penyakit mematikan ditandai dengan ploriferasi sel atau pembelahan sel yang tidakterkontrol. Pengobatan kanker dengan pembedahan dan radioterapi paling efektif untuk kanker lokal dannon-metastasis. Selain pengobatan secara medis, pasien penderita kanker juga menggunakan pengobatanherbal karena lebih rendahnya efek samping yang diberikan. Tujuan penelitian ini adalah untukmengetahui aktivitas senyawa phytol hasil ekstrak daun Zodia (Evodia sauveolens) sebagai antikankersecara in silico. Teknik penelitian ini secara in silico dimana menggunakan aplikasi komputer yangmelakukan kajian interaksi sekaligus memprediksi aktivitas senyawa hipotetik. Beberapa langkah yangdilakukan yaitu tahap preparasi sampel (koleksi ligan senyawa, koleksi protein, sterilisasi dan minimasi), tahapan molecular docking lalu tahapan visualisasi. Tanaman Zodia terbukti memiliki aktivitas antikankerbaik secara in vitro maupun in vivo dengan mengurangi aktivitas hambat pada proses proliferasi, metastasis, dan invasi, dan juga merangsang proses apoptosis berbagai jenis sel tumor. Pada penelitian inimenggunakan senyawa Phytol yang merupakan salah satu dari sekian banyak senyawa yang terkandungdi dalam ekstrak daun Zodia, dan memiliki potensi sebagai antikanker kolorektal secara in silico. Hasilpenelitian ini yaitu molecular docking antara senyawa phytol dengan protein ALK berupa data nilaibinding af inity sebesar -5,8 kcal/mol dan nilai RMSD 1,448 Å. Senyawa phytol tidak efektif untukdijadikan calon obat antikanker kolorektal, dilihat dari bioaktivitas senyawa phytol yang terlihat adanyaaktivitas antiinflamasi dari adanya penghambatan migrasi neutrophil, dan mengurangi inflamasiinterleukin (IL-1β) dan Tumor Necrosis Factor (TNF-α) dan stres oksidatif. Kata kunci: Kanker, Phytol, Zodia, In Silico
PENERAPAN TEKNOLOGI PRODUKSI SIMPLISIA EMPON-EMPON, KELOMPOK TANI KECAMATAN TRAWAS, KABUPATEN MOJOKERTO, JAWA TIMUR Mirwa Anggarani; Erlix Rakhmad Purnama; Raya Sulistyowati
Jurnal ABDI: Media Pengabdian Kepada Masyarakat Vol. 5 No. 1 (2019)
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/ja.v5n1.p1-5

Abstract

The community service aims to solve several main problems experienced by empon-empon farmers,namely the limited knowledge of the production techniques of empon-empon simplisia and the productionfacilities of empon-empon simplisia. These problems are experienced by partner "Gunung Jambe" SMEs,trawas sub-district, Mojokerto regency, East Java. To achieve the objectives of the PKM program, it isnecessary to introduce science and technology regarding: (1) optimizing the manufacture of export qualitysimons (SNI: 01-3393-1994); (2) analysis of the nutritional content of simplicia empon-empon; (3) analysisof shelf life of empon-empon simplicia products. The implementation of PKM activities was carried outbetween May and September 2019. Based on the analysis of the nutritional content of the empon-emponsimplicia product, it is known that the simplicia empon-empon contains 1.54% water; ash 9.45%;carbohydrates 86.70%; fat 0.91%; and protein 1.41%. From the results of the implementation of PKM inJune 2019, there was very high enthusiasm from PKM participants. In addition, there were some inputsfrom the trainees related to the next activity which were conveyed through the trainee questionnaire.
PELATIHAN PEMBUATAN SABUN ANTISEPTIK BERBAHAN DASAR EMPON-EMPON DI KABUPATEN NGANJUK Raya Sulistyowati; Mirwa Adiprahara Anggarani; Erlix Rakhmad Purnama; Dimas Avian Maulana; Tri Sudarwanto; Ricky Eka Putra
Jurnal ABDI: Media Pengabdian Kepada Masyarakat Vol. 6 No. 2 (2021)
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/ja.v6n2.p167-172

Abstract

Coronavirus 2019 (Covid-19) telah menjadi ancaman serius bagi semua masyarakat di setiap wilayah Indonesia bahkan di seluruh dunia. Setelah World Health Organization memutuskan bahwa Covid-19 menjadi pandemi global, berbagai peneliti berlomba-lomba menggali manfaat dari empon-empon untuk melawan Covid-19. Kandungan temulawak diyakini dapat mengatasi infeksi yang disebabkan Covid-19. Kabupaten Nganjuk merupakan salah satu daerah penghasil empon-empon. Namun, masyarakat Nganjuk masih memiliki pengetahuan yang kurang dalam mengolah empon-empon tersebut. Masyarakat sekitar masih sering mengalami gagal panen dalam penanaman empon-empon. Sehubungan dengan hal tersebut, pengenalan terhadap ilmu pengetahuan dan teknologi perlu dilakukan agar masyarakat Nganjuk mampu mengolah empon-empon tersebut menjadi suatu produk penangkal Covid-19. Dalam hal ini, empon-empon akan diolah menjadi sabun antiseptik yang bernilai ekonomis. Setelah berhasil memproduksi sabun tersebut, masyarakat Nganjuk juga dibekali dengan strategi pemasaran untuk memasarkan produk sabun antiseptik kepada pengguna.
The Development of Electronic-Worksheets (E-Worksheets) Based on Crosswords Games with Sub-Materials of The Excretory System to Improve The Motivation of High School Students Indiarti Dwi Fina; Raharjo Raharjo; Erlix Rakhmad Purnama
Berkala Ilmiah Pendidikan Biologi (BioEdu) Vol 11 No 3 (2022)
Publisher : Program Studi Pendidikan Biologi, FMIPA, Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/bioedu.v11n3.p691-698

Abstract

Education in the 4.0 industrial revolution era has a curriculum that utilizes the internet of things (IoT) as a source or media in the learning process. Learning media that support is e-worksheet with crosswords games that will help students be motivated in the learning process. This study aims to develop a valid and practical e-worksheet based on crossword games with sub-materials Excretory System to improve learning motivation of students. This study is development research that uses the ASSURE model with steps: Analyze learners, State objectives, Select method, media, and materials, Utilize materials, Require learners’ performance and Evaluate/Revise. The e-worksheet research trial included 20 students of XI grades from Muhammadiyah 10 Gresik. Validity was determined by material experts, media experts, and a biology teacher at SMA Muhammadiyah 10 Gresik. The practicality of the e-worksheet was determined using students’ response questionnaire, students’ motivation questionnaire before and after using the product, implementation of motivation, and student activities. Validity and practicality data were analyzed using the descriptive quantitative. The result showed that the developed e-worksheet obtained an average validity percentage of 98.14% with very valid criteria. The practical e-worksheet obtained 93.5% of students’ responses, the increase in students’ motivation improvement from 60.1% to 86.8%, and 91.67% observation motivations implementation. The data that is received shows that e-worksheet based on crossword games are very valid and practical. Keywords: e-Worksheet, Crosswords, Excretory System, Motivation
Pemanfaatan Daun Kelor (Moringa oleifera) Terhadap Pemulihan Struktur Pankreas Mencit Diabetik Wanodya Ayu Chandradevi; Muhammad Avesina; Dwi Puspita Anggriyawanti; Erlix Rakhmad Purnama
Biotropic : The Journal of Tropical Biology Vol. 2 No. 2 (2018): Biotropic, Volume 2, Nomor 2, 2018
Publisher : Program Studi Biologi, Fakultas Sains dan Teknologi, Universitas Islam Negeri Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/biotropic.2018.2.2.85-92

Abstract

Moringa oleifera tergolong mudah dijumpai di Indonesia dan mengandung senyawa quercetin yang termasuk dalam jenis flavonoid, dimana senyawa ini berperan sebagai agen hipoglikemik. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak Moringa oleifera terhadap kadar glukosa dan histopatologi pankreas mencit hiperglikemia. Metode yang digunakan pada penelitian ini yaitu ekstraksi daun Moringa oleifera dengan konsentrasi 42 mg/kgBB, 70 mg/kgBB, dan 98 mg/kgBB, lalu penginduksian aloksan secara intraperitoneal, pengaplikasian ekstrak Moringa oleifera, pengambilan organ pankreas dan pembuatan histologi organ pankreas. Hasil penelitian menunjukkan bahwa Pemberian ekstrak Moringa oleifera berpengaruh pada penurunan kadar glukosa dan penambahan diameter pulau Langerhans pankreas mencit diabetes. Konsentrasi ekstrak yang paling berpengaruh adalah 98 mg/kgBB. Maka dapat diambil simpulan bahwa ekstrak Moringa oleifera pada konsentrasi berpotensi sebagai antihiperglikemia.
Potensi Ekstrak Daun Bandotan (Ageratum conyzoides L.) Sebagai Spray Untuk Pemulihan Luka Mencit Diabetik Yang Terinfeksi Staphylococcus aureus Erra Ericha Safani; Wanodya Ayu Chandradevi Kunharjito; Alfiyan Lestari; Erlix Rakhmad Purnama
Biotropic : The Journal of Tropical Biology Vol. 3 No. 1 (2019): Biotropic, Volume 3, Nomor 1, 2019
Publisher : Program Studi Biologi, Fakultas Sains dan Teknologi, Universitas Islam Negeri Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/biotropic.2019.3.1.68-78

Abstract

Ageratum conyzoides L. leaf has the main compound of flavonoids and alkaloids that contribute to accelerate the healing process of diabetic ulcers with Staphylococcus aureus infection that can affect the quality of life of patients. This study aims to test the leaves of Ageratum conyzoides L. on the recovery of diabetic ulcers of mice infected with Staphylococcus aureus. The method used is the extraction of Ageratum conyzoides L leaves as the material of spray 15%, induction of diabetic compound (Alloxan monohydrate), length wound (1cm) and bacterial infections, and spray application with 1 times daily frequency, 2 times daily, 3 times a day for 9 days. The results showed that the lenght of wounds in group A, B, C, D, and E were 0,5; 0,8; 0,4; 0,2; 0,0. The administration of Ageratum conyzoides L. spray which has active flavonoide substances, alkaloid substance, and saponin substances has an effect on decreased length of diabetic wounds and restoration of dermis tissue structure (increases epithelial cells proliferation, initiates fibroblast cells, and stimulates type 1 collagen). Spray treatment 3 times a day (group E) was more influential than the other treatments, which experienced wound closure in 9 days. Thus, Ageratum conyzoides L. leaf spray is potential for therapy of diabetic ulcers infected with Staphylococcus aureus.
PROYEK LINTAS JENJANG SEBAGAI STRATEGI UNTUK MENINGKATKAN SIKAP DAN MOTIVASI BELAJAR IPA BAGI SISWA DISABILITAS: - Mirwa Adiprahara Anggarani; Aris Rudi Purnomo; Erlix Rakhmad Purnama; Dinda Herli Septiana; M. Nasir Nasir
Jurnal ABDI: Media Pengabdian Kepada Masyarakat Vol. 11 No. 2 (2026): JURNAL ABDI : Media Pengabdian Kepada masyarakat
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/abdi.v11i2.48389

Abstract

Putra Harapan Special Needs School in Waru, Sidoarjo, is a special needs school that provides education for students with disabilities or exceptional intelligence, either inclusively (joining a regular school) or as a special education unit. Several obstacles exist in the implementation of education, particularly in the teaching of science subjects. The physical, emotional, mental, or social limitations of students with special needs, coupled with the supporting infrastructure, often cannot optimally support science learning. These problems result in low attitudes and motivation to learn science among students with disabilities. The goal of the PKM program is to explore cross-level project methods suitable for students with disabilities to improve low attitudes and motivation to learn science. This is crucial to accommodate the learning needs of students with disabilities at both the individual and school level. Furthermore, specifically related to science material, learning this material requires a longer time compared to basic skills such as measurement and observation. In other words, cross-project learning has the benefit of time efficiency without minimizing the learning experience of students with disabilities. The novelty of this project is the collaboration between students with disabilities at different levels when completing science projects. Furthermore, the learning process, connected to the UDL concept, is an example of disability-friendly learning while still teaching critical thinking and problem-solving skills. The topic chosen in this cross-level science learning project is “My Telang My Expression”, where at the elementary school level, students are taught to recognize the parts of the telang tree, at the junior high school level, students are taught to cultivate telang and at the senior high school level, students are taught to make ecoprint bags from telang flowers. Through this program, there has been an increase in the quality of science learning which is reflected in the increase in attitudes and motivation to learn science thus improving science learning outcomes. In addition, there has been an increase in student learning outcomes at each level and an increase in teacher creativity in presenting learning materials. In this Abdimas Research scheme, a number of data will be produced as a representation of the program, which is also the research data that underlies the production of this cross-level project method.
Kontribusi Lembar Kerja Peserta Didik Elektronik (E-LKPD) melalui Model Problem Based Learning (PBL) untuk Melatih Keterampilan Berpikir Kritis Peserta Didik Kelas Xl SMA pada Materi Sistem Gerak Manusia Desinta Reninda Rokib; Raharjo; Erlix Rakhmad Purnama
Berkala Ilmiah Pendidikan Biologi (BioEdu) Vol. 15 No. 3 (2026)
Publisher : Program Studi Pendidikan Biologi, FMIPA, Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/bioedu.v15n3.p832-841

Abstract

Penelitian ini dirancang guna menganalisis kontribusi Lembar Kerja Peserta Didik Elektronik (E-LKPD) diintegrasikan dengan pendekatan Problem Based Learning (PBL) guna melatihkan keterampilan berpikir kritis siswa kelas XI SMA, khususnya pada topik Sistem Gerak Manusia. Penilaian terhadap E-LKPD mencakup tiga dimensi utama ialah validitas, kemudahan (kepraktisan), serta efektivitas. Aspek validitas dievaluasi melalui kualitas penyajian materi, kelengkapan isi, serta ketepatan penggunaan bahasa. Dimensi kepraktisan ditinjau dari tingkat keterlaksanaan proses pembelajaran serta tanggapan siswa. Dimensi efektivitas diukur berdasarkan peningkatan prestasi belajar melalui instrumen pretest dan post-test. Penelitian ini menerapkan model pengembangan 4-D yang mencakup empat fase yakni pendefinisian, perancangan, pengembangan, serta penyebaran. Partisipan penelitian terdiri atas 20 siswa dari kelas XI-1 SMA Negeri 2 Sidoarjo. Temuan penelitian mengindikasikan bahwa E-LKPD melalui pendekatan PBL memberikan kontribusi terhadap keterampilan berpikir kritis siswa. E-LKPD tersebut termasuk kategori sangat valid dengan perolehan skor 98,93%, sangat praktis ditinjau dari aspek keterlaksanaan pembelajaran mencapai 100% serta respon siswa mencapai 98,70%, efektif dalam mengembangkan kemampuan berpikir kritis dengan nilai N-Gain sebesar 0,80 termasuk kategori tinggi serta keseluruhan siswa mencapai standar ketuntasan. Dengan demikian, implementasi E-LKPD berbasis PBL terbukti secara empiris dan teoritis memberikan dampak positif serta signifikan dalam meningkatkan keterampilan berpikir kritis siswa kelas XI SMA topik Sistem Gerak Manusia.
Analysis of DNA Quality in Nile Tilapia (Oreochromis niloticus) Liver Tissue Based on Differences in Distribution Sources (Traditional Markets and Supermarkets) Rahayu Endarwati; Adinda Revalina Putri; Moh. Arif Setiawan; Tiana Belinda Maharani; Regina Martha Ayu; Rossa Indira Rahmadhini; Erlix Rakhmad Purnama; Lisa Lisdiana
Jurnal Biologi Tropis Vol. 26 No. 4 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i4.12600

Abstract

DNA quality is an important molecular parameter that reflects the integrity of an organism’s genetic material. Nile tilapia (Oreochromis niloticus) is a high-value aquaculture commodity distributed through various marketing channels, including traditional markets and modern supermarkets. Differences in postharvest handling practices, storage conditions, and hygiene standards may influence the biological quality of fish, although these factors were not directly evaluated in this study. This study aimed to compare the DNA quality of Nile tilapia liver tissue obtained from traditional markets and supermarkets through DNA isolation using the meBEP kit, measurement of DNA concentration and purity with a NanoDrop spectrophotometer, DNA amplification by PCR, and visualization using agarose gel electrophoresis. NanoDrop measurements showed that samples from the traditional market (N1) had higher DNA concentrations (50.8–56.8 ng/µL) than samples from the supermarket (N2), which ranged from 3.1 to 6.1 ng/µL. The A260/A280 ratio of group N1 was more stable and closer to the expected range for pure DNA (1.63–1.66) than that of group N2 (0.78–1.54). However, all samples exhibited A260/A230 ratios well below the ideal value, indicating the presence of non-protein contaminants in the DNA isolates. Agarose gel electrophoresis showed no visible DNA bands for either the isolated DNA or the PCR products in both sample groups. These results indicate that, under the isolation and amplification conditions used in this study, the extracted DNA was of insufficient quality to serve as a reliable PCR template. The observed differences between sample groups should therefore be interpreted descriptively, as postharvest factors such as distribution time and storage temperature were not measured.