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Rachmat Kosman
Fakultas Farmasi Universitas Muslim Indonesia Makassar
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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UJI AKTIVITAS IMUNOGLOBULIN M (IgM) EKSTRAK ETANOL HERBA RUMPUT MUTIARA (Hedyotis corymbosa) PADA MENCIT (Mus musculus) JANTAN DENGAN METODE HEMAGLUTINASI Safriani Rahman; Bayu Putra; Rachmat Kosman; Riska Mustika
As-Syifaa Jurnal Farmasi Vol 4, No 2 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.346 KB) | DOI: 10.33096/jifa.v4i2.79

Abstract

A Research About Activity of Ethanol of Pearl Grass (Hedyotis corymbosa) On The Imunoglobulin M (IgM) by Hemaglutination Method Had Been Conducted of Male Mice. This research purpose to established of activity imunoglobulin M (IgM) from ethanol extract of pearl grass (Hedyotis corymbosa). Mice is animal that used for this research,The mice was divided into 4 treatment groups, where each group consisted of 3 mice. The first group as negative control, and each group was given Sheel Red Blood Cell (SRBC) 2 % as many 0,1 ml intraperitonially, after that negative control group was administrated with air sulingt, and other group was administrated with ethanol extract  dose 26 mg, 78 mg, dan 130 mg for five days. The blood from all group was collected by intracardial after five days. The activity of imunoglobulin M (IgM) was measured by hemaglutination method based on titer of the imunoglobulin M (IgM) there was highest dilution of mice blood serum in which aglutination was showed. Research result showed   Ethanol extract of Pearl Grass (Hedyotis corymbosa) at 26 mg, 78 mg, and 130 mg dose, can increased imunoglobulin M (IgM) activity.Key words : Imunoglobulin M, Hedyotis corymbosa, Hemaglutination Method
PRODUKSI SEDIAAN KOMBUCHA DARI DAUN PERMOT (Passiflora foetida L) SECARA FERMENTASI Herwin Herwin; Rachmat Kosman; Iswan Siami
As-Syifaa Jurnal Farmasi Vol 5, No 1 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.595 KB) | DOI: 10.33096/jifa.v5i1.65

Abstract

A research has been done about profit of permot leaves (Passiflora foetida L.) by using culture of kombucha with the aim to know the use of permot leaves (Passiflora foetida L.) as preparation of kombucha in a fermentation. Permot dried leaves boiled in 1000 ml water until boiling then got extract of permot. Extract of permot leaves added with 100 gram glucose and 10% of inoculum kombucha culture then fermented for 5 – 12 days. The results of kombucha preparation from permot leaves then testing with organoleptic, measuring pH and total acid test. Based of the results in preparation kombucha permot leaves (Passiflora foetida L.) showed that the  color-test organoleptic with hedonic method was obtained values 2.5, flavor 1.9, and taste 2.4. pH measurement before fermentation is 4 and after that is 3 with total acid of 0.66%. Key Word : Permot Leaves (Passiflora foetida L.), Fermentation, Kombucha of Preparation
PENGARUH EFEK EKSTRAK ETANOL DAUN MURBEI (Morus multicaulis) SEBAGAI ANTIOKSIDAN PADA PARU – PARU TIKUS (Rattus norvegicus) JANTAN YANG DIPAPAR ASAP ROKOK DENGAN PARAMETER HISTOPATOLOGI Muhammad Asri; Rachmat Kosman; Dewi Yuliana
As-Syifaa Jurnal Farmasi Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.062 KB) | DOI: 10.33096/jifa.v7i2.2

Abstract

This research aimed to see antioxidant effect of extract ethanol leaves of Murbei (Morus multicaulis) in the lung hispathology of rats who get cigarette smoke exposure. The research method is have been done with experimental, 25 male rats (Rattus norvegicus) with 2-5 month old, body weigh range 100-200 gram were treated for 31 days. Devide in to 5 groups, P1 positive control (has given food and drink), P2 negative control (with cigarette smoke exposure), P3 (a group treated by cigarette smoke exposure and extract ethanol Murbei 100 mg/kgBB), P4 (a group treated by cigarette smoke exposure and extract ethanol Murbei 200 mg/kgBB), P5 (a group treated by cigarette smoke exposure and vitamin E 1,8 mg/kgBB). In 31st day, the mice performed surgery to retrieve organs rat lung histopathology test is then performed. Given ethanol extract of leaves of Murbei (Morus multicaulis) 100 mg/kgBB and 200 mg/kgBB may have an effect as an antioxidant in the lungs of rat (Rattus norvegicus) males
Co-Authors A Amaliah Dahlia Aco Mappacanda Bayu Putra Dewi Yuliana Fitriani Fitriani Halija Halija Herwin Herwin Iswan Siami Muhammad Asri Pirman AP Riska Mustika Safriani Rahman Sukmawati Syarif, Sukmawati