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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Labora Medika IJMS - Indonesian Journal on Medical Science Indonesian Journal of Community Services Jurnal Ilmiah Cendekia Eksakta Jurnal Inovasi Teknik Kimia Jurnal Farmasi JAFP (Jurnal Akademi Farmasi Prayoga) Indonesian Journal on Medical Science (IJMS) Media Farmasi Indonesia Journal of Clinical Pharmacy and Pharmaceutical Science Jurnal Ilmiah Medsains
Maria Mita Susanti
Politeknik Katolik Mangunwijaya
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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ANALISIS KARAKTERISTIK MUTU SABUN TRANSPARAN BEKATUL BERAS MERAH (Oryza nivara) BERBAHAN DASAR MINYAK GORENG BEKAS Maria Mita Susanti; Syela Puspitaningtyas
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 16, No 02 (2019): Jurnal Ilmu Farmasi & farmasi Klinik Vol 16 No 02 Desember 2019
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.512 KB) | DOI: 10.31942/jiffk.v16i02.3235

Abstract

ABSTRACT The free radicals exposure from daily activities can cause the damage the skin, therefore to avoid this damage effect can use antioxidants compounds . Brown rice bran is rice milling waste which has high antioxidant with IC50 is 43,2349 ppm. Efforts to increase the economic value of rice bran high in antioxidant compounds is by processing rice bran into transparent soap products. This research was conducted to analyze the quality characteristics of transparent red rice bran soap (Oryza nivara) based on used cooking oil. The quality characteristics of transparent rice soap which includes organoleptic soap, pH, foam power, free alkali, and water content. The data were analyzed descriptively by comparing the results of research with SNI 06-3532 -1994 Based on the results of the study obtained the results of the characteristics of soap that meets the quality characteristics of SNI 06-3532-1994 soap requirements with a pH of 10,2 , foam power of 2,54 cm, free alkali of 0,034%, and 3,85% moisture content. Keywords : transparent soap, brown rice bran, used cooking oil, solid soap quality characteristics
Pengaruh Konsentrasi KOH Terhadap Kadar Alkali Bebas Sabun Cair Ekstrak Daun Waru Laut (Hibiscus Tiliaceus L.) Fadlika Febriyani; Maria Mita Susanti
Jurnal Akademi Farmasi Prayoga Vol 7 No 2 (2022): JURNAL AKADEMI FARMASI PRAYOGA
Publisher : Akademi Farmasi Prayoga Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56350/jafp.v7i2.84

Abstract

Abstrak Sabun cair merupakan pembersih yang dibuat dengan reaksi kimia antara basa dengan asam lemak yang disebut sebagai proses saponifikasi. Basa yang digunakan dalam pembuatan sabun cair adalah KOH. Kualitas mutu sabun dapat ditingkatkan dengan penambahan bahan alam salah satunya tanaman waru laut yang mengandung senyawa saponin, flavanoid, polifenol, triterpenoid, berkasiat sebagai antioksidan dan antifungi. Berdasarkan SNI bahwa kadar alkali bebas untuk sediaan sabun cair dengan basa KOH <0,14%. Tujuan dari penelitian ini untuk mengetahui pengaruh penambahan KOH terhadap kadar alkali bebas pada sabun cair. Jenis penelitian ini adalah ekperimental dengan rancangan penelitihan acak lengkap satu faktor pada penambahan konsentrasi KOH (10%, 15%, 25%). Uji karakteristik mutu meliputi organoleptis, pH, tinggi busa, dan alkali bebas. Data yang diperoleh kemudian dianalisis secara teoritis yaitu data hasil pengujian karakteristik mutu dan kadar alkali bebas pada sediaan sabun cair dibandingkan dengan persyaratan yang terdapat dalam SNI. Data yang diperoleh dianalisis homogenitas dan kemudian dilanjutkan dengan uji Anova, apabila data yang diperoleh tidak normal dan homogen maka dilanjutkan dengan uji Kruskal-Wallis. Hasil penelitian yang diperoleh yaitu pada uji organoleptis berbentuk cair, berwarna coklat kehijauan, beraroma khas, pH ketiga formula memiliki rentang 9- 11, uji daya busa 2,02 - 2,27 cm dan kadar alkali bebas sebesar 0,08% yang telah memenuhi persyaratan SNI, 1996. Hasil uji anova didapatkan (p<0,05) maka dapat disimpulkan bahwa konsentrasi KOH berpengaruh terhadap kadar alkali bebas.
PENGARUH TEMPAT TUMBUH TERHADAP KADAR LOGAM BERAT TIMBAL (Pb), CADMIUM (Cd) dan TEMBAGA (Cu) EKSTRAK RIMPANG JAHE EMPRIT (Zingiber officinale Var. amarum) DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM Maria Mita Susanti; Dita Dwi Ariyanti; Silvi Ardianti; Wieke Febriawan Citra Mahanani
Jurnal Inovasi Teknik Kimia Vol 8, No 1 (2023)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v18i1.8093

Abstract

Pengaruh Perbedaan Perasan Dan Ekstrak Kulit Pisang Mas (Musa Acuminata Colla) Terhadap Kadar Vitamin C Dengan Metode Spektrofotometri Uv- Vis Andriana, Azizah Huda; Susanti, Maria Mita
Indonesian Journal on Medical Science Vol 11 No 1 (2024): IJMS 2024
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Bhakti Mulial

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55181/ijms.v11i1.459

Abstract

Banana is a type of plant that is abundant in Indonesia, but the utilization of waste peels has not been done optimally. The peel of the golden banana (Musa acuminata Colla) contains vitamin C. It is necessary to pay attention to the processing of the peel of the golden banana because vitamin C is easily oxidized by heat, light and metals. This study aims to determine the effect of banana peel filtrate and extract on vitamin C levels. This type of research is experimental. The independent variables were the filtrate and golden banana peel extract with the dependent variable namely the organoleptic levels of vitamin C in the filtrate and golden banana peel extract. The test was carried out qualitatively with Benedict's reagent, FeSO4 & NaOH and quantitatively using UV-Vis spectrophotometry with a wavelength of 265 nm. The results of measuring vitamin C levels were analyzed using SPSS with the Independent T-Test test. The qualitative test results showed that the filtrate and banana peel extract positively contained vitamin C. The level of vitamin C in the filtrate was 0.1538918% w/w (153.892 mg/100 g) while in the extract it was 0.1065812% w/w (106.581 mg/w 100g). Based on the results of analysis of mas banana peel filtrate and mas banana peel extract, it has an effect on Vitamin C levels with a p value <0.05
ANALISIS PENGARUH PERENDAMAN LARUTAN KULIT SINGKONG (Manihot esculenta Cortex) TERHADAP KANDUNGAN LOGAM BERAT TIMBAL (Pb) DALAM KERANG DARAH (Anadara granosa) Susanti, Maria Mita; Priamsari, Margareta Retno
Media Farmasi Indonesia Vol. 12 No. 2 (2017): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.435 KB)

Abstract

ABSTRACKMussles blood (Anadara granosa) is a type of shell that is often consumed by Indonesian community. The shells have non selective feeder and sessile filter that relatively high which mean heavy metal content is found in the shell’s body due to the accumulation of the heavy metals. In an effort to reduce heavy metals in mussles blood, it can be done using the utilization of cassava skin waste. Cassava skin can be used as a material of reducing the heavy metal content of Pb (Lead) in mussles because it contains cellulose that can modify the group to produce hydroxyl which can bind Pb metal ions. This research aimed to analyze the effect of soaking of cassava skin solution (Manihot esculenta Cortex) with decreasing level of heavy metal lead (Pb) on mussles blood (Anadara granosa). This was an experimental research with treatment of cassava skin concentration of 1%, 1.5% and 3% and soaking time 10 minutes, 40 minutes and 80 minutes. The independent variables are concentration of cassava skin solution, soaking time and dependent variable in this research is Pb concentration in mussles blood (Anadara granosa). Samples were analyzed using an Atomic Absorption Spectrophotometer (SSA). The data were analyzed using Kendall's Tau test. The results showed that there was influence of decreasing percentage of heavy metal Pb on soaking time (p <0.05) but did not affect to concentration of cassava skin solution (p> 0.05).
Effect Of Ethanol Concentration In Waru Leaf Extract (Hibiscus Tiliaceus L.) On Lead Levels Of Metal (Pb) Using Atomic Absorption Spectrophotometry Susanti, Maria Mita
Media Farmasi Indonesia Vol. 18 No. 1 (2023): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v18i1.216

Abstract

Waru leaves are able to absorb lead in the air so that it has the potential to accumulate lead. Lead is a heavy metal that is toxic, originating from exhaust gases from motor vehicles and industry. Waru leaves can be used as a traditional medicinal plant by taking the active compounds in extract preparations. The solvent used in the manufacture of the extract is ethanol because it is a polar solvent which can potentially reduce Pb metal which is polar. This study aims to determine the effect of ethanol concentration as a solvent in waru leaf extract (Hibiscus tiliaceus L.) on Pb levels using Atomic Absorption Spectrophotometry (AAS). This research is an experimental research. The independent variable in this study was the variation in ethanol concentration while the dependent variable in this study was Pb levels. The extraction method used was remaceration with 96% ethanol, 70% ethanol and 50% ethanol and the samples were tested quantitatively by atomic absorption spectrophotometry. The lowest lead content in hibiscus leaves was hibiscus leaf extract with 70% ethanol solvent of 0.053 mg/kg. Statistical results using the Oneway ANOVA test obtained a sig value of 0.475 (p>0.05) so that there was no significant effect of variations in the concentration of 50% ethanol, 70% ethanol and 96% ethanol in hibiscus leaf extract on levels of heavy metal Pb.
Effect of Analytical Method on Vitamin C Tablet Levels Stored under Different Temperature Conditions Susanti, Maria Mita
Media Farmasi Indonesia Vol. 19 No. 2 (2024): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v19i2.272

Abstract

Vitamin C tablets are commonly consumed by the public as antioxidant supplements. Vitamin C is highly susceptible to oxidation, which is accelerated by factors such as heat, light, alkali, enzymes, oxidizers, and the presence of copper and iron catalysts. Oxidation will be inhibited if vitamin C is left in an acidic state or at low temperatures. However, many vitamin C tablets are not stored according to recommended conditions due to inadequate temperature control during storage or distribution, leading to changes in their vitamin C levels. Vitamin C levels can be analyzed using the Iodimetry method and UV-Vis spectrophotometry. This study aims to determine the effect of the analysis method on the content of vitamin C tablets stored at various temperature variations. This is an experimental research. The independent variable of this study is the analytical method of determining vitamin C content and the dependent variable of this research is the content of vitamin tablets stored at low temperature (2-6°C), room temperature (27-30°C), and high temperature (48°C). Quantitative analysis of vitamin C levels was conducted using both iodimetry and UV-Vis spectrophotometry methods. The highest vitamin C content was found in the analysis of levels using the UV-Vis spectrophotometry method. Statistical analysis shows significant differences, indicating that the method of analyzing the levels of vitamin C tablets stored under varying temperature conditions affects the levels of vitamin C tablets.
ANALISIS VARIASI KONSENTRASI KALIUM HIDROKSIDA TERHADAP KARAKTERISTIK MUTU SABUN MANDI CAIR EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) BERBAHAN DASAR MINYAK GORENG BEKAS Susanti, Maria Mita; Tyaspito, Nicolas Adi
CENDEKIA EKSAKTA Vol. 8 No. 1 (2023)
Publisher : Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/ce.v8i1.8259

Abstract

Xanthone merupakan senyawa utama pada kulit buah manggis yang berfungsi sebagai antioksidan karena mempunyai nilai IC50 sebesar 17,90 ppm. Senyawa antioksidan dapat digunakan dalam produk sabun sebagai penangkal radikal bebas. Sabun terbentuk dari proses reaksi hidrolisis basa terhadap lemak atau minyak. KOH dalam reaksi saponifikasi sebagai alkali yang akan direaksikan dengan minyak sehingga menghasilkan sintesa dan air serta garam karbonil. Karakteristik mutu sabun cair dipengaruhi oleh konsentrasi KOH yang digunakan. Tujuan penelitian ini untuk mengetahui karakteristik mutu sabun mandi cair dengan menggunakan zat aktid dari ekstrak kulit buah manggis (Garcinia mangostana L.) dengan bahan dasar minyak goreng bekas dengan variasi konsentrasi KOH (7,35 %, 9,1 % , 10,85 %). Jenis penelitian ini adalah penelitian eksperimental dengan variabel bebas yang digunakan adalah variasi konsentrasi KOH dan variabel terikat adalah karakteristik mutu sabun cair yang meliputi organolpetis, pH, daya busa, viskositas, asam lemak bebas dan alkali bebas. Data dianalisa secara deskriptif melalui pendekatan teoritis data dibandingkan dengan persyaratan dalam pustaka SNI 06-4085-1996. Berdasarkan hasil penelitian dapat disimpulkan bahwa karakteristik mutu sabun mandi cair yang memenuhi standar sni 06-4085-1996 adalah pH, tinggi busa, alkali bebas, asam lemak bebas sedangkan viskositas belum memenuhi karakteristik mutu sabun cair yang baik.Kata kunci: karakteristik mutu sabun cair, kulit manggis, minyak goreng bekas, variasi konsentrasi kalium hidroksida
PENGARUH METODE PENGERINGAN TERHADAP KUALITAS EKSTRAK DAN KADAR FLAVONOID TOTAL EKSTRAK ETANOLIK DAUN SAMBUNG NYAWA (Gynura procumbens (Lour.) Merr.) Retno Priamsari, Margareta; Mita Susanti, Maria; Harya Atmaja, Andreas
Jurnal Farmasi (Journal of Pharmacy) Vol. 5 No. 1 (2016): Jurnal Farmasi (Journal of Pharmacy), October 2016
Publisher : Jurnal Farmasi (Journal of Pharmacy)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Flavonoids is one active compounds in the Gynura procumbens (Lour.) Merr. leaves for antioxidant, inhibiting of cancer cells, and maintaining liver function. Flavonoid is thermolabile compound and need proper post harvest handling. The purpose of this study is to the determine effect of drying method on the quality of extract and total flavonoids content in ethanolic extract of Gynura procumbens (Lour.) Merr. leaves. This type of research is experimental. Drying methods used in this research are by wind drying under shade place from direct sunlight and oven drying in 40o C temperature. Analysis of total flavonoids content using colorimetric method with AlCl3 complexing compounds and quercetin standard. Standard calibration curve was made 5 series concentrations of 40, 60, 80, 100, and 120 ppm. The absorbance was read at 434 nm wavelength of Uv Vis spectrophotometer. Data obtained in the form of lower levels of flavonoids are analyzed statistically with a pair of independent sample t -test. The results showed if drying methods make a significant different of quality extract and total flavonoids content ethanolic extract of Gynura procumbens (Lour.) Merr leaves. Total flavonoids content with wind drying method is 2.15 ± 0.03% w/w and total flavonoid content with 40oC oven drying method is 1.87 ± 0.01% w/w. The total flavonoid content is counted as quercetin.
Pemanfaatan Limbah Minyak Goreng Bekas dan Bekatul Menjadi Sabun Antiaging Mita Susanti, Maria; Retno Priamsari, Margareta
Jurnal Farmasi (Journal of Pharmacy) Vol. 8 No. 1 (2019): Jurnal Farmasi (Journal of Pharmacy), October 2019
Publisher : Jurnal Farmasi (Journal of Pharmacy)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Used cooking oil and rice bran is waste that has less economic value. The use of cooking oil repeatedly causes the fatty acids contained in the oil to be more saturated. Changes in the nature of cooking oil make cooking oil unfit for use as food because it can cause health effects on the body. Meanwhile, the availability of rice bran which is very abundant and nutrition of rice bran that contains a high antioxidant has not been comparable with its limited utilization. The research objective is to treat used cooking oil waste and rice bran waste to be processed into anti-aging soap products. This was an experimental research with the independent variable is bran soap formula and the dependent variable is the quality characteristics of bran soap which includes organoleptic test, pH, foam power, free alkali and vitamin E. The data were analyzed descriptively by comparing the results of research with SNI 06-3532 -1994. The results showed rice bran soap that meets the quality requirements is formula II, which is obtained results that meet the soap quality requirements in theory which includes solid organoleptic tests, typical odorous rice bran and brown, pH 11 test, 2,28 cm foam power test, acid test 0,46% free fat, 0,1% free alkaline test and positive contain vitamin E.
Co-Authors admjurnalsiji polibara Alicia Dinta Assuncao Guterres Andriana, Azizah Huda Devi Oktavia Dita Dwi Ariyanti Fadlika Febriyani Harya Atmaja, Andreas Jessica Margareta Jaya Jessica Margareta Jaya Liana - Politeknik Katolik Mangunwijaya, Nurhafni Audi Margareta Retno Priamsari Monica Kristiani Nurhafni Audi Liana - Politeknik Katolik Mangunwijaya Priskalia Inge Sriwening Retno Priamsari, Margareta Silvi Ardianti Syela Puspitaningtyas Toni Juliantoro, Benediktus Tyaspito, Nicolas Adi Wieke Febriawan Citra Mahanani