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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Labora Medika IJMS - Indonesian Journal on Medical Science Indonesian Journal of Community Services Jurnal Ilmiah Cendekia Eksakta Jurnal Inovasi Teknik Kimia Jurnal Farmasi JAFP (Jurnal Akademi Farmasi Prayoga) Indonesian Journal on Medical Science (IJMS) Media Farmasi Indonesia Jurnal Ilmiah Medsains Journal of Clinical Pharmacy and Pharmaceutical Science
Maria Mita Susanti
Politeknik Katolik Mangunwijaya
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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ANALISIS KARAKTERISTIK MUTU SABUN TRANSPARAN BEKATUL BERAS MERAH (Oryza nivara) BERBAHAN DASAR MINYAK GORENG BEKAS Maria Mita Susanti; Syela Puspitaningtyas
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 16, No 02 (2019): Jurnal Ilmu Farmasi & farmasi Klinik Vol 16 No 02 Desember 2019
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.512 KB) | DOI: 10.31942/jiffk.v16i02.3235

Abstract

ABSTRACT The free radicals exposure from daily activities can cause the damage the skin, therefore to avoid this damage effect can use antioxidants compounds . Brown rice bran is rice milling waste which has high antioxidant with IC50 is 43,2349 ppm. Efforts to increase the economic value of rice bran high in antioxidant compounds is by processing rice bran into transparent soap products. This research was conducted to analyze the quality characteristics of transparent red rice bran soap (Oryza nivara) based on used cooking oil. The quality characteristics of transparent rice soap which includes organoleptic soap, pH, foam power, free alkali, and water content. The data were analyzed descriptively by comparing the results of research with SNI 06-3532 -1994 Based on the results of the study obtained the results of the characteristics of soap that meets the quality characteristics of SNI 06-3532-1994 soap requirements with a pH of 10,2 , foam power of 2,54 cm, free alkali of 0,034%, and 3,85% moisture content. Keywords : transparent soap, brown rice bran, used cooking oil, solid soap quality characteristics
PENGARUH PENAMBAHAN KALIUM HIDROKSIDA (KOH) TERHADAP MUTU SABUN LUNAK BERBAHAN DASAR MINYAK GORENG BEKAS Maria Mita Susanti; Alicia Dinta Assuncao Guterres
Jurnal Ilmiah Medsains Vol 4 No 1 (2018): Edisi Desember
Publisher : Unit Penelitian dan Pengabdian Masyarakat, Politeknik Banjarnegara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.781 KB)

Abstract

The increasing of pollution, dirt, sweat and bacteria on skin surface, make the need for soap increase. One form of soap is soft soap, which made from potassium salt with fatty acids. The oil phase that can be used is cooking oil with a frequency of three times frying. The purpose of this study is to determine the effect of addition of potassium hydroxide on the quality characteristics of soft soap produced. This type of research is an experimental study with a complete randomized design study of one factor on the addition of potassium hydroxide (13 g, 15 g and 17 g). Quality characteristics tests include organoleptic, pH, foam power, moisture content, free alkali and free fatty acids. Data were analyzed theoretically and statistically using Shapiro-Wilk for data normality, and Levene Statistic for data homogeneity. Normal and homogeneous data were followed by Anova test, and normal but not homogeneous data followed by Kruskal-Wallis test. Based on the results of the characteristic test showed that formula II met the quality characteristics test of soft soap, with a pH value of 10, foam power 2,26-2,30 cm, moisture content 44%, free alkali 0,08%, and free fatty acids 1,42%. Formula I does not meet the foam power test (2,20 cm) which is 2,03-2,06 cm, while the formula III does not meet the pH test requirements (7-10) that is 11. Based on the results of the data analysis the three formulas show the value (p<0,05) means that the addition of potassium hydroxide affects the quality characteristics of soft soap.
PENGARUH VARIASI KONSENTRASI KATALIS ASAM SULFAT PEKAT TERHADAP HASIL DERAJAT ESTERIFIKASI ETIL LAURAT admjurnalsiji polibara; Maria Mita Susanti; Jessica Margareta Jaya
Jurnal Ilmiah Medsains Vol 6 No 2 (2020): Edisi Desember
Publisher : Unit Penelitian dan Pengabdian Masyarakat, Politeknik Banjarnegara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.143 KB)

Abstract

Ethyl laurate can be synthesized through an esterification process by reacting lauric acid and ethanol plus H2SO4(p) as a catalyst. The esterification reaction requires a catalyst to accelerate the reaction besides the influence of the addition of the catalyst concentration also affects the ester results so it is necessary to do research that aims to determine the effect of catalyst H2SO4(p) concentration on the results of ethyl lauric esterification. This type of research is an experimental study to determine the effect of variations in H2SO4 catalyst concentration on the synthesis results of ethyl laurate. The experimental design used in this study was a factorial Completely Randomized Design (CRD), which was a comparison of the variation in catalyst H2SO4(p) concentration. The variables observed were variations in H2SO4 (1%, 2%, 3%, 4% and 5%) catalyst concentrations on the esterification degree reacted for 5 hours with a comparison of the variation of the molar ratio of lauric acid and ethanol used 1: 7. Analysis of statistical data obtained was tested using the Oneway Anova test. The results showed that variations in H2SO4(p) catalyst concentration had an effect on the results of the esterification degree. The best degree of esterification was obtained at concentration catalyst H2SO4(p) 4%, which amounted to 90.24%. Statistical data analysis obtained a significant value of 0,000 (p <0.05) which means that there is an influence of variations in the catalyst concentration on the synthesis results of ethyl laurate. Keywords: H2SO4(p) Catalyst Consentration, Ethyl Laurate, Esterification Degree.
Pengaruh Konsentrasi KOH Terhadap Kadar Alkali Bebas Sabun Cair Ekstrak Daun Waru Laut (Hibiscus Tiliaceus L.) Fadlika Febriyani; Maria Mita Susanti
Jurnal Akademi Farmasi Prayoga Vol 7 No 2 (2022): JURNAL AKADEMI FARMASI PRAYOGA
Publisher : Akademi Farmasi Prayoga Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56350/jafp.v7i2.84

Abstract

Abstrak Sabun cair merupakan pembersih yang dibuat dengan reaksi kimia antara basa dengan asam lemak yang disebut sebagai proses saponifikasi. Basa yang digunakan dalam pembuatan sabun cair adalah KOH. Kualitas mutu sabun dapat ditingkatkan dengan penambahan bahan alam salah satunya tanaman waru laut yang mengandung senyawa saponin, flavanoid, polifenol, triterpenoid, berkasiat sebagai antioksidan dan antifungi. Berdasarkan SNI bahwa kadar alkali bebas untuk sediaan sabun cair dengan basa KOH <0,14%. Tujuan dari penelitian ini untuk mengetahui pengaruh penambahan KOH terhadap kadar alkali bebas pada sabun cair. Jenis penelitian ini adalah ekperimental dengan rancangan penelitihan acak lengkap satu faktor pada penambahan konsentrasi KOH (10%, 15%, 25%). Uji karakteristik mutu meliputi organoleptis, pH, tinggi busa, dan alkali bebas. Data yang diperoleh kemudian dianalisis secara teoritis yaitu data hasil pengujian karakteristik mutu dan kadar alkali bebas pada sediaan sabun cair dibandingkan dengan persyaratan yang terdapat dalam SNI. Data yang diperoleh dianalisis homogenitas dan kemudian dilanjutkan dengan uji Anova, apabila data yang diperoleh tidak normal dan homogen maka dilanjutkan dengan uji Kruskal-Wallis. Hasil penelitian yang diperoleh yaitu pada uji organoleptis berbentuk cair, berwarna coklat kehijauan, beraroma khas, pH ketiga formula memiliki rentang 9- 11, uji daya busa 2,02 - 2,27 cm dan kadar alkali bebas sebesar 0,08% yang telah memenuhi persyaratan SNI, 1996. Hasil uji anova didapatkan (p<0,05) maka dapat disimpulkan bahwa konsentrasi KOH berpengaruh terhadap kadar alkali bebas.
PENGARUH TEMPAT TUMBUH TERHADAP KADAR LOGAM BERAT TIMBAL (Pb), CADMIUM (Cd) dan TEMBAGA (Cu) EKSTRAK RIMPANG JAHE EMPRIT (Zingiber officinale Var. amarum) DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM Maria Mita Susanti; Dita Dwi Ariyanti; Silvi Ardianti; Wieke Febriawan Citra Mahanani
Jurnal Inovasi Teknik Kimia Vol 8, No 1 (2023)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v18i1.8093

Abstract

ANALISIS CEMARAN LOGAM BERAT KADMIUM (Cd) DALAM JAMU PEGAL LINU DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Gabriel Lauranita Geovanny Devi; Maria Mita Susanti
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 1 No. 1 (2022): April: Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v1i1.2

Abstract

Pegal linu traditional medicine is one of tradisional medicine that are in great demand by the community, such as in the district of Mranggen, Demak, as much as 66,50% of the people consume pegal linu traditional medicine. One of the security aspects that need to be considered in traditional medicine is the presence of heavy metal contamination. The research aims to determine the levels of Cd heavy metals in pegal linu traditional medicine with capsule dosage forms that are based on the district of Mranggen, Demak are in accordance with the regulation of BPOM RI in 2014 regrading heavy metal contamination in traditional medicines, ≤ 0,3 mg/kg. This research use explorative experimental, including : sampling, sample preparation used wet closed destruction method with HNO3 and H2SO4 (3:1)  of the destruction solution in the Kjeldhal flask, qualitative analysis of Cd with color test and Cd quantitative analysis using Atomic Absorption Spectroscopy (AAS). The results of the quantitative analysis in this study did not show the metal content of Cd, this was due the small Cd content in the sample. Quantitative analysis shows that the Cd level in 12 sampels of pegal linu traditional medicine circulating in the distric of Mranggen, Demak exceeded the threshold of heavy metal contamination determined by BPOM RI in 2014 with the highest average levels of 18,86 mg/kg and the lower average levels of 7,38 mg/kg.  
Pengaruh Perbedaan Perasan Dan Ekstrak Kulit Pisang Mas (Musa Acuminata Colla) Terhadap Kadar Vitamin C Dengan Metode Spektrofotometri Uv- Vis Andriana, Azizah Huda; Susanti, Maria Mita
Indonesian Journal on Medical Science Vol 11 No 1 (2024): IJMS 2024
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Bhakti Mulial

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55181/ijms.v11i1.459

Abstract

Banana is a type of plant that is abundant in Indonesia, but the utilization of waste peels has not been done optimally. The peel of the golden banana (Musa acuminata Colla) contains vitamin C. It is necessary to pay attention to the processing of the peel of the golden banana because vitamin C is easily oxidized by heat, light and metals. This study aims to determine the effect of banana peel filtrate and extract on vitamin C levels. This type of research is experimental. The independent variables were the filtrate and golden banana peel extract with the dependent variable namely the organoleptic levels of vitamin C in the filtrate and golden banana peel extract. The test was carried out qualitatively with Benedict's reagent, FeSO4 & NaOH and quantitatively using UV-Vis spectrophotometry with a wavelength of 265 nm. The results of measuring vitamin C levels were analyzed using SPSS with the Independent T-Test test. The qualitative test results showed that the filtrate and banana peel extract positively contained vitamin C. The level of vitamin C in the filtrate was 0.1538918% w/w (153.892 mg/100 g) while in the extract it was 0.1065812% w/w (106.581 mg/w 100g). Based on the results of analysis of mas banana peel filtrate and mas banana peel extract, it has an effect on Vitamin C levels with a p value <0.05
ANALISIS PENGARUH PERENDAMAN LARUTAN KULIT SINGKONG (Manihot esculenta Cortex) TERHADAP KANDUNGAN LOGAM BERAT TIMBAL (Pb) DALAM KERANG DARAH (Anadara granosa) Susanti, Maria Mita; Priamsari, Margareta Retno
Media Farmasi Indonesia Vol. 12 No. 2 (2017): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.435 KB)

Abstract

ABSTRACKMussles blood (Anadara granosa) is a type of shell that is often consumed by Indonesian community. The shells have non selective feeder and sessile filter that relatively high which mean heavy metal content is found in the shell’s body due to the accumulation of the heavy metals. In an effort to reduce heavy metals in mussles blood, it can be done using the utilization of cassava skin waste. Cassava skin can be used as a material of reducing the heavy metal content of Pb (Lead) in mussles because it contains cellulose that can modify the group to produce hydroxyl which can bind Pb metal ions. This research aimed to analyze the effect of soaking of cassava skin solution (Manihot esculenta Cortex) with decreasing level of heavy metal lead (Pb) on mussles blood (Anadara granosa). This was an experimental research with treatment of cassava skin concentration of 1%, 1.5% and 3% and soaking time 10 minutes, 40 minutes and 80 minutes. The independent variables are concentration of cassava skin solution, soaking time and dependent variable in this research is Pb concentration in mussles blood (Anadara granosa). Samples were analyzed using an Atomic Absorption Spectrophotometer (SSA). The data were analyzed using Kendall's Tau test. The results showed that there was influence of decreasing percentage of heavy metal Pb on soaking time (p <0.05) but did not affect to concentration of cassava skin solution (p> 0.05).
Effect Of Ethanol Concentration In Waru Leaf Extract (Hibiscus Tiliaceus L.) On Lead Levels Of Metal (Pb) Using Atomic Absorption Spectrophotometry Susanti, Maria Mita
Media Farmasi Indonesia Vol. 18 No. 1 (2023): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v18i1.216

Abstract

Waru leaves are able to absorb lead in the air so that it has the potential to accumulate lead. Lead is a heavy metal that is toxic, originating from exhaust gases from motor vehicles and industry. Waru leaves can be used as a traditional medicinal plant by taking the active compounds in extract preparations. The solvent used in the manufacture of the extract is ethanol because it is a polar solvent which can potentially reduce Pb metal which is polar. This study aims to determine the effect of ethanol concentration as a solvent in waru leaf extract (Hibiscus tiliaceus L.) on Pb levels using Atomic Absorption Spectrophotometry (AAS). This research is an experimental research. The independent variable in this study was the variation in ethanol concentration while the dependent variable in this study was Pb levels. The extraction method used was remaceration with 96% ethanol, 70% ethanol and 50% ethanol and the samples were tested quantitatively by atomic absorption spectrophotometry. The lowest lead content in hibiscus leaves was hibiscus leaf extract with 70% ethanol solvent of 0.053 mg/kg. Statistical results using the Oneway ANOVA test obtained a sig value of 0.475 (p>0.05) so that there was no significant effect of variations in the concentration of 50% ethanol, 70% ethanol and 96% ethanol in hibiscus leaf extract on levels of heavy metal Pb.
Pengaruh Cemaran Logam Berat Kadmium (CD) Terhadap Bentuk Sediaan Jahe Emprit (Zingiber Officinale Var. Amarum) Devi Oktavia; Maria Mita Susanti
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 2 No. 2 (2023): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v2i2.40

Abstract

The high productivity of ginger in Indonesia ranks fifth out of the ten largest ginger producing countries in the world, for example emprit ginger (Zingiber officinale var. Amarum). Emprit ginger is usually processed into dosage forms such as powder and extract which are widely used as a spicy and off-flavor enhancer in drinks, food or traditional medicine. The growth of emprit ginger plants can be influenced by heavy metal contamination which has toxic effects and is easily absorbed, such as Cadmium (Cd), so that heavy metal Cd contamination needs to be considered as a quality requirement in the manufacture of traditional medicines and processed foods. This study aims to determine the levels and differences in heavy metal Cd contamination in the dosage form of emprit ginger using the Atomic Absorption Spectrophotometry (AAS) method. The type of research used is experimental research. The independent variable of this research is the dosage form of emprit ginger and the dependent variable is Cd metal content. The data obtained were then tested using the Independent Sample T-Test. The results of cadmium (Cd) metal contamination levels in the powder dosage form were an average of - 0.2183 mg/kg and thick extracts with an average of - 0.2225 mg/kg. The results of statistical tests using the Independent Sample T-Test showed that there was no influence of heavy metal Cd contamination on the dosage form of emprit ginger (p>0.05).
Co-Authors admjurnalsiji polibara Alicia Dinta Assuncao Guterres Andriana, Azizah Huda Devi Oktavia Dita Dwi Ariyanti Fadlika Febriyani Gabriel Lauranita Geovanny Devi Harya Atmaja, Andreas Jessica Margareta Jaya Kristiani, Monica Liana - Politeknik Katolik Mangunwijaya, Nurhafni Audi Margareta Retno Priamsari Monica Kristiani Nurhafni Audi Liana - Politeknik Katolik Mangunwijaya Priskalia Inge Sriwening Retno Priamsari, Margareta Silvi Ardianti Syela Puspitaningtyas Toni Juliantoro, Benediktus Tyaspito, Nicolas Adi Wieke Febriawan Citra Mahanani