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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Labora Medika IJMS - Indonesian Journal on Medical Science Indonesian Journal of Community Services Jurnal Ilmiah Cendekia Eksakta Jurnal Inovasi Teknik Kimia Jurnal Farmasi JAFP (Jurnal Akademi Farmasi Prayoga) Indonesian Journal on Medical Science (IJMS) Media Farmasi Indonesia Jurnal Ilmiah Medsains Journal of Clinical Pharmacy and Pharmaceutical Science
Maria Mita Susanti
Politeknik Katolik Mangunwijaya
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Effect of Analytical Method on Vitamin C Tablet Levels Stored under Different Temperature Conditions Susanti, Maria Mita
Media Farmasi Indonesia Vol. 19 No. 2 (2024): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v19i2.272

Abstract

Vitamin C tablets are commonly consumed by the public as antioxidant supplements. Vitamin C is highly susceptible to oxidation, which is accelerated by factors such as heat, light, alkali, enzymes, oxidizers, and the presence of copper and iron catalysts. Oxidation will be inhibited if vitamin C is left in an acidic state or at low temperatures. However, many vitamin C tablets are not stored according to recommended conditions due to inadequate temperature control during storage or distribution, leading to changes in their vitamin C levels. Vitamin C levels can be analyzed using the Iodimetry method and UV-Vis spectrophotometry. This study aims to determine the effect of the analysis method on the content of vitamin C tablets stored at various temperature variations. This is an experimental research. The independent variable of this study is the analytical method of determining vitamin C content and the dependent variable of this research is the content of vitamin tablets stored at low temperature (2-6°C), room temperature (27-30°C), and high temperature (48°C). Quantitative analysis of vitamin C levels was conducted using both iodimetry and UV-Vis spectrophotometry methods. The highest vitamin C content was found in the analysis of levels using the UV-Vis spectrophotometry method. Statistical analysis shows significant differences, indicating that the method of analyzing the levels of vitamin C tablets stored under varying temperature conditions affects the levels of vitamin C tablets.
ANALISIS VARIASI KONSENTRASI KALIUM HIDROKSIDA TERHADAP KARAKTERISTIK MUTU SABUN MANDI CAIR EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) BERBAHAN DASAR MINYAK GORENG BEKAS Susanti, Maria Mita; Tyaspito, Nicolas Adi
CENDEKIA EKSAKTA Vol. 8 No. 1 (2023)
Publisher : Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/ce.v8i1.8259

Abstract

Xanthone merupakan senyawa utama pada kulit buah manggis yang berfungsi sebagai antioksidan karena mempunyai nilai IC50 sebesar 17,90 ppm. Senyawa antioksidan dapat digunakan dalam produk sabun sebagai penangkal radikal bebas. Sabun terbentuk dari proses reaksi hidrolisis basa terhadap lemak atau minyak. KOH dalam reaksi saponifikasi sebagai alkali yang akan direaksikan dengan minyak sehingga menghasilkan sintesa dan air serta garam karbonil. Karakteristik mutu sabun cair dipengaruhi oleh konsentrasi KOH yang digunakan. Tujuan penelitian ini untuk mengetahui karakteristik mutu sabun mandi cair dengan menggunakan zat aktid dari ekstrak kulit buah manggis (Garcinia mangostana L.) dengan bahan dasar minyak goreng bekas dengan variasi konsentrasi KOH (7,35 %, 9,1 % , 10,85 %). Jenis penelitian ini adalah penelitian eksperimental dengan variabel bebas yang digunakan adalah variasi konsentrasi KOH dan variabel terikat adalah karakteristik mutu sabun cair yang meliputi organolpetis, pH, daya busa, viskositas, asam lemak bebas dan alkali bebas. Data dianalisa secara deskriptif melalui pendekatan teoritis data dibandingkan dengan persyaratan dalam pustaka SNI 06-4085-1996. Berdasarkan hasil penelitian dapat disimpulkan bahwa karakteristik mutu sabun mandi cair yang memenuhi standar sni 06-4085-1996 adalah pH, tinggi busa, alkali bebas, asam lemak bebas sedangkan viskositas belum memenuhi karakteristik mutu sabun cair yang baik.Kata kunci: karakteristik mutu sabun cair, kulit manggis, minyak goreng bekas, variasi konsentrasi kalium hidroksida
PENGARUH METODE PENGERINGAN TERHADAP KUALITAS EKSTRAK DAN KADAR FLAVONOID TOTAL EKSTRAK ETANOLIK DAUN SAMBUNG NYAWA (Gynura procumbens (Lour.) Merr.) Retno Priamsari, Margareta; Mita Susanti, Maria; Harya Atmaja, Andreas
Jurnal Farmasi (Journal of Pharmacy) Vol. 5 No. 1 (2016): Jurnal Farmasi (Journal of Pharmacy), October 2016
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Flavonoids is one active compounds in the Gynura procumbens (Lour.) Merr. leaves for antioxidant, inhibiting of cancer cells, and maintaining liver function. Flavonoid is thermolabile compound and need proper post harvest handling. The purpose of this study is to the determine effect of drying method on the quality of extract and total flavonoids content in ethanolic extract of Gynura procumbens (Lour.) Merr. leaves. This type of research is experimental. Drying methods used in this research are by wind drying under shade place from direct sunlight and oven drying in 40o C temperature. Analysis of total flavonoids content using colorimetric method with AlCl3 complexing compounds and quercetin standard. Standard calibration curve was made 5 series concentrations of 40, 60, 80, 100, and 120 ppm. The absorbance was read at 434 nm wavelength of Uv Vis spectrophotometer. Data obtained in the form of lower levels of flavonoids are analyzed statistically with a pair of independent sample t -test. The results showed if drying methods make a significant different of quality extract and total flavonoids content ethanolic extract of Gynura procumbens (Lour.) Merr leaves. Total flavonoids content with wind drying method is 2.15 ± 0.03% w/w and total flavonoid content with 40oC oven drying method is 1.87 ± 0.01% w/w. The total flavonoid content is counted as quercetin.
Pemanfaatan Limbah Minyak Goreng Bekas dan Bekatul Menjadi Sabun Antiaging Mita Susanti, Maria; Retno Priamsari, Margareta
Jurnal Farmasi (Journal of Pharmacy) Vol. 8 No. 1 (2019): Jurnal Farmasi (Journal of Pharmacy), October 2019
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Used cooking oil and rice bran is waste that has less economic value. The use of cooking oil repeatedly causes the fatty acids contained in the oil to be more saturated. Changes in the nature of cooking oil make cooking oil unfit for use as food because it can cause health effects on the body. Meanwhile, the availability of rice bran which is very abundant and nutrition of rice bran that contains a high antioxidant has not been comparable with its limited utilization. The research objective is to treat used cooking oil waste and rice bran waste to be processed into anti-aging soap products. This was an experimental research with the independent variable is bran soap formula and the dependent variable is the quality characteristics of bran soap which includes organoleptic test, pH, foam power, free alkali and vitamin E. The data were analyzed descriptively by comparing the results of research with SNI 06-3532 -1994. The results showed rice bran soap that meets the quality requirements is formula II, which is obtained results that meet the soap quality requirements in theory which includes solid organoleptic tests, typical odorous rice bran and brown, pH 11 test, 2,28 cm foam power test, acid test 0,46% free fat, 0,1% free alkaline test and positive contain vitamin E.
Analisa Karakteristik Mutu Sabun Padat Ekstrak Kulit Buah Manggis (Garcinia Mangostana L.) Berbahan Dasar Minyak Jelantah Mita Susanti, Maria; Toni Juliantoro, Benediktus
Jurnal Farmasi (Journal of Pharmacy) Vol. 10 No. 2 (2021): Jurnal Farmasi (Journal of Pharmacy), October 2021
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

The use of used cooking oil can cause various diseases when consumed and will even cause environmental pollution if disposed of without processing. Therefore, efforts need to be made to utilize used cooking oil into products that can increase economic value, one of which is oil-based products such as solid soap. A good soap is not only able to clean the skin from dirt, but also contains substances that can counteract the effects of free radicals such as antioxidants. Mangosteen rind (Garcinia mangostana L.) is a source of natural antioxidants containing xanthones with an IC50 of 2.710 ppm. This study aims to make and analyze the quality characteristics of solid soap mangosteen rind extract based on used cooking oil. This study analyzed the quality characteristics of solid soap preparations including organoleptic tests, pH, free fatty acid levels, foam stability, water content and free alkali levels. Data analysis was done descriptively. The results showed that the quality characteristics of solid soap were in accordance with the quality requirements, namely organoleptic solid form, pH 10, foam stability 89.33%, moisture content 14.33%, free fatty acid content 1.54% and free alkali content 0.07%.
Co-Authors admjurnalsiji polibara Alicia Dinta Assuncao Guterres Andriana, Azizah Huda Devi Oktavia Dita Dwi Ariyanti Fadlika Febriyani Gabriel Lauranita Geovanny Devi Harya Atmaja, Andreas Jessica Margareta Jaya Kristiani, Monica Liana - Politeknik Katolik Mangunwijaya, Nurhafni Audi Margareta Retno Priamsari Monica Kristiani Nurhafni Audi Liana - Politeknik Katolik Mangunwijaya Priskalia Inge Sriwening Retno Priamsari, Margareta Silvi Ardianti Syela Puspitaningtyas Toni Juliantoro, Benediktus Tyaspito, Nicolas Adi Wieke Febriawan Citra Mahanani