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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Labora Medika IJMS - Indonesian Journal on Medical Science Indonesian Journal of Community Services Jurnal Ilmiah Cendekia Eksakta Jurnal Inovasi Teknik Kimia Jurnal Farmasi JAFP (Jurnal Akademi Farmasi Prayoga) Indonesian Journal on Medical Science (IJMS) Media Farmasi Indonesia Jurnal Ilmiah Medsains Journal of Clinical Pharmacy and Pharmaceutical Science
Maria Mita Susanti
Politeknik Katolik Mangunwijaya
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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PENGARUH METODE PENGERINGAN TERHADAP KUALITAS EKSTRAK DAN KADAR FLAVONOID TOTAL EKSTRAK ETANOLIK DAUN SAMBUNG NYAWA (Gynura procumbens (Lour.) Merr.) Retno Priamsari, Margareta; Mita Susanti, Maria; Harya Atmaja, Andreas
Jurnal Farmasi (Journal of Pharmacy) Vol. 5 No. 1 (2016): Jurnal Farmasi (Journal of Pharmacy), October 2016
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Flavonoids is one active compounds in the Gynura procumbens (Lour.) Merr. leaves for antioxidant, inhibiting of cancer cells, and maintaining liver function. Flavonoid is thermolabile compound and need proper post harvest handling. The purpose of this study is to the determine effect of drying method on the quality of extract and total flavonoids content in ethanolic extract of Gynura procumbens (Lour.) Merr. leaves. This type of research is experimental. Drying methods used in this research are by wind drying under shade place from direct sunlight and oven drying in 40o C temperature. Analysis of total flavonoids content using colorimetric method with AlCl3 complexing compounds and quercetin standard. Standard calibration curve was made 5 series concentrations of 40, 60, 80, 100, and 120 ppm. The absorbance was read at 434 nm wavelength of Uv Vis spectrophotometer. Data obtained in the form of lower levels of flavonoids are analyzed statistically with a pair of independent sample t -test. The results showed if drying methods make a significant different of quality extract and total flavonoids content ethanolic extract of Gynura procumbens (Lour.) Merr leaves. Total flavonoids content with wind drying method is 2.15 ± 0.03% w/w and total flavonoid content with 40oC oven drying method is 1.87 ± 0.01% w/w. The total flavonoid content is counted as quercetin.
Pemanfaatan Limbah Minyak Goreng Bekas dan Bekatul Menjadi Sabun Antiaging Mita Susanti, Maria; Retno Priamsari, Margareta
Jurnal Farmasi (Journal of Pharmacy) Vol. 8 No. 1 (2019): Jurnal Farmasi (Journal of Pharmacy), October 2019
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Used cooking oil and rice bran is waste that has less economic value. The use of cooking oil repeatedly causes the fatty acids contained in the oil to be more saturated. Changes in the nature of cooking oil make cooking oil unfit for use as food because it can cause health effects on the body. Meanwhile, the availability of rice bran which is very abundant and nutrition of rice bran that contains a high antioxidant has not been comparable with its limited utilization. The research objective is to treat used cooking oil waste and rice bran waste to be processed into anti-aging soap products. This was an experimental research with the independent variable is bran soap formula and the dependent variable is the quality characteristics of bran soap which includes organoleptic test, pH, foam power, free alkali and vitamin E. The data were analyzed descriptively by comparing the results of research with SNI 06-3532 -1994. The results showed rice bran soap that meets the quality requirements is formula II, which is obtained results that meet the soap quality requirements in theory which includes solid organoleptic tests, typical odorous rice bran and brown, pH 11 test, 2,28 cm foam power test, acid test 0,46% free fat, 0,1% free alkaline test and positive contain vitamin E.
Analisa Karakteristik Mutu Sabun Padat Ekstrak Kulit Buah Manggis (Garcinia Mangostana L.) Berbahan Dasar Minyak Jelantah Mita Susanti, Maria; Toni Juliantoro, Benediktus
Jurnal Farmasi (Journal of Pharmacy) Vol. 10 No. 2 (2021): Jurnal Farmasi (Journal of Pharmacy), October 2021
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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The use of used cooking oil can cause various diseases when consumed and will even cause environmental pollution if disposed of without processing. Therefore, efforts need to be made to utilize used cooking oil into products that can increase economic value, one of which is oil-based products such as solid soap. A good soap is not only able to clean the skin from dirt, but also contains substances that can counteract the effects of free radicals such as antioxidants. Mangosteen rind (Garcinia mangostana L.) is a source of natural antioxidants containing xanthones with an IC50 of 2.710 ppm. This study aims to make and analyze the quality characteristics of solid soap mangosteen rind extract based on used cooking oil. This study analyzed the quality characteristics of solid soap preparations including organoleptic tests, pH, free fatty acid levels, foam stability, water content and free alkali levels. Data analysis was done descriptively. The results showed that the quality characteristics of solid soap were in accordance with the quality requirements, namely organoleptic solid form, pH 10, foam stability 89.33%, moisture content 14.33%, free fatty acid content 1.54% and free alkali content 0.07%.
Pengaruh Cemaran Logam Berat Kadmium (CD) Terhadap Bentuk Sediaan Jahe Emprit (Zingiber Officinale Var. Amarum) Devi Oktavia; Maria Mita Susanti
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 2 No. 2 (2023): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v2i2.40

Abstract

The high productivity of ginger in Indonesia ranks fifth out of the ten largest ginger producing countries in the world, for example emprit ginger (Zingiber officinale var. Amarum). Emprit ginger is usually processed into dosage forms such as powder and extract which are widely used as a spicy and off-flavor enhancer in drinks, food or traditional medicine. The growth of emprit ginger plants can be influenced by heavy metal contamination which has toxic effects and is easily absorbed, such as Cadmium (Cd), so that heavy metal Cd contamination needs to be considered as a quality requirement in the manufacture of traditional medicines and processed foods. This study aims to determine the levels and differences in heavy metal Cd contamination in the dosage form of emprit ginger using the Atomic Absorption Spectrophotometry (AAS) method. The type of research used is experimental research. The independent variable of this research is the dosage form of emprit ginger and the dependent variable is Cd metal content. The data obtained were then tested using the Independent Sample T-Test. The results of cadmium (Cd) metal contamination levels in the powder dosage form were an average of - 0.2183 mg/kg and thick extracts with an average of - 0.2225 mg/kg. The results of statistical tests using the Independent Sample T-Test showed that there was no influence of heavy metal Cd contamination on the dosage form of emprit ginger (p>0.05).
Co-Authors admjurnalsiji polibara Alicia Dinta Assuncao Guterres Andriana, Azizah Huda Devi Oktavia Dita Dwi Ariyanti Fadlika Febriyani Harya Atmaja, Andreas Jessica Margareta Jaya Liana - Politeknik Katolik Mangunwijaya, Nurhafni Audi Margareta Retno Priamsari Monica Kristiani Nurhafni Audi Liana - Politeknik Katolik Mangunwijaya Priskalia Inge Sriwening Retno Priamsari, Margareta Silvi Ardianti Syela Puspitaningtyas Toni Juliantoro, Benediktus Tyaspito, Nicolas Adi Wieke Febriawan Citra Mahanani