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Analisa Karakteristik Mutu Sabun Padat Ekstrak Kulit Buah Manggis (Garcinia Mangostana L.) Berbahan Dasar Minyak Jelantah Mita Susanti, Maria; Toni Juliantoro, Benediktus
Jurnal Farmasi (Journal of Pharmacy) Vol. 10 No. 2 (2021): Jurnal Farmasi (Journal of Pharmacy), October 2021
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

The use of used cooking oil can cause various diseases when consumed and will even cause environmental pollution if disposed of without processing. Therefore, efforts need to be made to utilize used cooking oil into products that can increase economic value, one of which is oil-based products such as solid soap. A good soap is not only able to clean the skin from dirt, but also contains substances that can counteract the effects of free radicals such as antioxidants. Mangosteen rind (Garcinia mangostana L.) is a source of natural antioxidants containing xanthones with an IC50 of 2.710 ppm. This study aims to make and analyze the quality characteristics of solid soap mangosteen rind extract based on used cooking oil. This study analyzed the quality characteristics of solid soap preparations including organoleptic tests, pH, free fatty acid levels, foam stability, water content and free alkali levels. Data analysis was done descriptively. The results showed that the quality characteristics of solid soap were in accordance with the quality requirements, namely organoleptic solid form, pH 10, foam stability 89.33%, moisture content 14.33%, free fatty acid content 1.54% and free alkali content 0.07%.
Pengaruh Cemaran Logam Berat Kadmium (CD) Terhadap Bentuk Sediaan Jahe Emprit (Zingiber Officinale Var. Amarum) Devi Oktavia; Maria Mita Susanti
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 2 No. 2 (2023): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v2i2.40

Abstract

The high productivity of ginger in Indonesia ranks fifth out of the ten largest ginger producing countries in the world, for example emprit ginger (Zingiber officinale var. Amarum). Emprit ginger is usually processed into dosage forms such as powder and extract which are widely used as a spicy and off-flavor enhancer in drinks, food or traditional medicine. The growth of emprit ginger plants can be influenced by heavy metal contamination which has toxic effects and is easily absorbed, such as Cadmium (Cd), so that heavy metal Cd contamination needs to be considered as a quality requirement in the manufacture of traditional medicines and processed foods. This study aims to determine the levels and differences in heavy metal Cd contamination in the dosage form of emprit ginger using the Atomic Absorption Spectrophotometry (AAS) method. The type of research used is experimental research. The independent variable of this research is the dosage form of emprit ginger and the dependent variable is Cd metal content. The data obtained were then tested using the Independent Sample T-Test. The results of cadmium (Cd) metal contamination levels in the powder dosage form were an average of - 0.2183 mg/kg and thick extracts with an average of - 0.2225 mg/kg. The results of statistical tests using the Independent Sample T-Test showed that there was no influence of heavy metal Cd contamination on the dosage form of emprit ginger (p>0.05).
PENGARUH VARIASI KONSENTRASI KATALIS ASAM SULFAT PEKAT TERHADAP HASIL DERAJAT ESTERIFIKASI ETIL LAURAT Jessica Margareta Jaya; Maria Mita Susanti
Jurnal Ilmiah Medsains Vol 6 No 02 (2020): Jurnal Ilmiah Medsains
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Banjarnegara

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Abstract

Ethyl laurate can be synthesized through an esterification process by reacting lauric acid and ethanol plus H2SO4(p) as a catalyst. The esterification reaction requires a catalyst to accelerate the reaction besides the influence of the addition of the catalyst concentration also affects the ester results so it is necessary to do research that aims to determine the effect of catalyst H2SO4(p) concentration on the results of ethyl lauric esterification. This type of research is an experimental study to determine the effect of variations in H2SO4 catalyst concentration on the synthesis results of ethyl laurate. The experimental design used in this study was a factorial Completely Randomized Design (CRD), which was a comparison of the variation in catalyst H2SO4(p) concentration. The variables observed were variations in H2SO4 (1%, 2%, 3%, 4% and 5%) catalyst concentrations on the esterification degree reacted for 5 hours with a comparison of the variation of the molar ratio of lauric acid and ethanol used 1: 7. Analysis of statistical data obtained was tested using the Oneway Anova test. The results showed that variations in H2SO4(p) catalyst concentration had an effect on the results of the esterification degree. The best degree of esterification was obtained at concentration catalyst H2SO4(p) 4%, which amounted to 90.24%. Statistical data analysis obtained a significant value of 0,000 (p <0.05) which means that there is an influence of variations in the catalyst concentration on the synthesis results of ethyl laurate.