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All Journal Jurnal Kimia Riset Chimica et Natura Acta
Fauzia Indah Sabila
Universitas Negeri Surabaya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Materials Science & Nanotechnology

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Phytochemical Screening and Total Phenolic Compounds of Red Ginger (Zingiber officinale) and Secang Wood (Caesalpinia sappan) As Preliminary Test of Antiarthritis Rizka Tazky Amalia; Tukiran Tukiran; Fauzia Indah Sabila; Suyatno Suyatno
Chimica et Natura Acta Vol 9, No 1 (2021)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v9.n1.34230

Abstract

Rheumatoid arthritis is an auto-immune disease that causes chronic inflammation occurs of the joints. Rheumatoid arthritis is characterized by the the overproduction of proinflammation cytokines such as TNF-α and IL-1. The phenolic compounds mainly anthocyanin and elagitanin have TNF-α inhibition activity that induces cyclooxygenase-2 expressions that cause inflammation. Phytochemical screening showed that ethanol extract of red ginger contains alkaloids, phenolics, flavonoids, tannins, terpenoid, and steroids while ethanol extract of secang wood contains alkaloids, phenolics, flavonoids, tannins, and terpenoid. This research aims to identify the secondary metabolite qualitatively and total phenolic compunds on red ginger and secang wood with Folin-Ciocalteu method. Total phenolic compounds are defined as the Gallic Acid Equivalent (GAE). The results showed that the total phenolic compunds of red ginger and sappan wood were 21.90 mg GAE/g extract and 27.65 mg GAE/g extract, respectively. The phenolic compounds in red ginger and secang wood have the potential as antiarthritic.
AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN KELOR (Moringa oleifera Lam.) DAN BUAH BIT (Beta vulgaris L.) SEBAGAI BAHAN TAMBAHAN MINUMAN SUPLEMEN , Tukiran; Mauren Gita Miranti; Idah Dianawati; fauzia indah sabila
Jurnal Kimia Riset Vol. 5 No. 2 (2020): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v5i2.22518

Abstract

Minuman suplemen merupakan produk pelengkap kebutuhan zat gizi makanan yang mempunyai nilai gizi dan atau efek fisiologis dalam jumlah terkonsentrasi. Bahan tambahan dalam minuman suplemen dapat diperoleh dari tanaman yang memiliki aktivitas antioksidan. Daun kelor dan buah bit merupakan tanaman yang banyak dimanfaatkan sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan ektstrak daun kelor dan buah bit sebagai bahan tambahan minuman suplemen.  Uji aktivitas antioksidan dilakukan dengan metode 1,1-diphenyl-1-pyerilhidrazyl (DPPH). Hasil penelitian menunjukkan  ekstrak air daun kelor memiliki nilai IC50 sebesar 122,742 ppm dan tergolong sebagai antioksidan katagori sedang. Kkstrak air buah bit memiliki nilai IC50 sebesar 377.281 ppm dan tergolong antioksidan lemah.
Co-Authors , Tukiran Idah Dianawati Mauren Gita Miranti Rizka Tazky Amalia Suyatno Sutoyo Tukiran Tukiran