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Phytochemical Screening and Total Phenolic Compounds of Red Ginger (Zingiber officinale) and Secang Wood (Caesalpinia sappan) As Preliminary Test of Antiarthritis Rizka Tazky Amalia; Tukiran Tukiran; Fauzia Indah Sabila; Suyatno Suyatno
Chimica et Natura Acta Vol 9, No 1 (2021)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v9.n1.34230

Abstract

Rheumatoid arthritis is an auto-immune disease that causes chronic inflammation occurs of the joints. Rheumatoid arthritis is characterized by the the overproduction of proinflammation cytokines such as TNF-α and IL-1. The phenolic compounds mainly anthocyanin and elagitanin have TNF-α inhibition activity that induces cyclooxygenase-2 expressions that cause inflammation. Phytochemical screening showed that ethanol extract of red ginger contains alkaloids, phenolics, flavonoids, tannins, terpenoid, and steroids while ethanol extract of secang wood contains alkaloids, phenolics, flavonoids, tannins, and terpenoid. This research aims to identify the secondary metabolite qualitatively and total phenolic compunds on red ginger and secang wood with Folin-Ciocalteu method. Total phenolic compounds are defined as the Gallic Acid Equivalent (GAE). The results showed that the total phenolic compunds of red ginger and sappan wood were 21.90 mg GAE/g extract and 27.65 mg GAE/g extract, respectively. The phenolic compounds in red ginger and secang wood have the potential as antiarthritic.
AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN KELOR (Moringa oleifera Lam.) DAN BUAH BIT (Beta vulgaris L.) SEBAGAI BAHAN TAMBAHAN MINUMAN SUPLEMEN , Tukiran; Mauren Gita Miranti; Idah Dianawati; fauzia indah sabila
Jurnal Kimia Riset Vol. 5 No. 2 (2020): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v5i2.22518

Abstract

Minuman suplemen merupakan produk pelengkap kebutuhan zat gizi makanan yang mempunyai nilai gizi dan atau efek fisiologis dalam jumlah terkonsentrasi. Bahan tambahan dalam minuman suplemen dapat diperoleh dari tanaman yang memiliki aktivitas antioksidan. Daun kelor dan buah bit merupakan tanaman yang banyak dimanfaatkan sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan ektstrak daun kelor dan buah bit sebagai bahan tambahan minuman suplemen.  Uji aktivitas antioksidan dilakukan dengan metode 1,1-diphenyl-1-pyerilhidrazyl (DPPH). Hasil penelitian menunjukkan  ekstrak air daun kelor memiliki nilai IC50 sebesar 122,742 ppm dan tergolong sebagai antioksidan katagori sedang. Kkstrak air buah bit memiliki nilai IC50 sebesar 377.281 ppm dan tergolong antioksidan lemah.
AKTIVITAS ANTIOKSIDAN DARI FRAKSI n-HEKSANA KULIT BATANG TUMBUHAN JAMBU SEMARANG (Syzygium samarangense) Irene Cornelia Constanty; Tukiran Tukiran
Jurnal Kimia Riset Vol. 6 No. 1 (2021): Juni
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v6i1.24467

Abstract

Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan ekstrak tumbuhan jambu semarang khususnya pada fraksi n-heksana. Pada penelitian ini, serbuk kering kulit batang tumbuhan tersebut diekstraksi dengan cara maserasi. Kemudian dipartisi secara berturut-turut menggunakan pelarut n-heksana, diklorometana, dan etil asetat. Pada tahap partisi, rendemen yang diperoleh berturut-turut pada masing-masing pelarut n-heksana, diklorometana, etil asetat, dan metanol akhir adalah 2,88%; 12,54%; 45,17%; dan 29,9%. Uji aktivitas antioksidan terhadap fraksi n-heksana menggunakan metode DPPH menghasilkan nilai IC50 sebesar 206,549 ppm. Dengan demikian dapat disimpulkan bahwa fraksi n-heksana kulit batang tumbuhan jambu semarang memiliki aktivitas antioksidan dengan kategori lemah karena nilai IC50 berkisar antara 100-250 ppm.
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN KEJIBELING (Strobilanthes crispa L., Blume) DAN DAUN SAMBILOTO (Andrographis paniculata Burm. f. Nees) DAN KOMBINASINYA Norviria Tsalasatin Apriliani; Tukiran Tukiran
Jurnal Kimia Riset Vol. 6 No. 1 (2021): Juni
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v6i1.26634

Abstract

Kejibeling (Strobilanthes crispa L., Blume) dan Sambiloto (Andrographis paniculata Burm. f. Nees) adalah tanaman yang mempunyai kandungan senyawa bioaktif yang memiliki potensi sebagai antioksidan. Penelitian ini memiliki tujuan untuk mengetahui aktivitas antioksidan kombinasi ekstrak etanol daun kejibeling dan daun sambiloto. Pengujian antioksidan sampel menggunakan metode DPPH secara spektrofotometer UV-Vis. Serbuk daun kejibeling dan sambiloto dimaserasi dengan menggunakan pelarut etanol 96% sampai diperoleh ekstrak kental setelah penguapan. Hasil uji aktivitas antioksidan didapatkan nilai IC50 untuk ekstrak etanol kejibeling, ekstrak etanol sambiloto, kombinasi ekstrak kejibeling:sambiloto (1:1), kombinasi (1:2) dan kombinasi (2:1) berturut-turut sebesar 71,39624, 15,55574, 7,585932, 7,836343 dan 6,359931 ppm. Nilai IC50 kombinasi ekstrak dari daun kejibeling dan sambiloto menunjukkan adanya peningkatan kemampuan antioksidan dibandingkan dengan ekstrak tunggal.
Pelatihan Pembuatan Hand Sanitizer Non Alkohol Berbasis Tanaman Obat Keluarga Tukiran Tukiran; Suyatno Suyatno; I Gusti Made Sanjaya; Nita Kusumawati; Dina Kartika Maharani
E-Dimas: Jurnal Pengabdian kepada Masyarakat Vol 12, No 3 (2021): E-DIMAS
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/e-dimas.v12i3.6931

Abstract

Dalam masa pandemi covid-19 ini, masyarakat rawan akan kesehatan mereka jika tidak ditanamkankebiasaan sesuai dengan SOP kesehatan, termasuk warga Perumahan Pondok Ridho, desa Sidodadi, kecamatan Taman, kabupaten Sidoarjo. Untuk itu, Tim PKM bermaksud untuk memberikan pelatihan bagi warga tersebut untukmembuat produk hand sanitizer yang non-alkohol. Hand sanitizer non-alkohol yang diproduksi ini menggunakanbahan-bahan alami yang sebenarnya sebagian sudah tersedia di sekitar mereka, yakni daun sirih danjeruk nipis.Namun, sebagian juga masih digunakan bahan-bahan kimia seperti gliserin dan hidrogenperoksida, yang masing-masing berfungsi sebagai humektan dan antiseptik. Dari kegiatan PKMproduksi hand sanitizernon-alkohol berbahan TOGA ini telah dihasilkan: (1) panduan pembuatanhandsanitizer non-alkohol berbahan tanaman TOGA yang dilengkapi materi kajianmengenai manfaat daun sirih dan buah jeruk nipis, serta lembar penilaian keterampilan dan lembar angket peserta,(2) pemaparan isi materi tersebut secara lisan dimana tim PKM dan mitra tetap mengikuti protokolkesehatan, (3) pembuatan handsanitizer non-alkohol berbahan TOGA dengan melibatkan pesertapelatihan menggunakan bahan-bahan yang telah disediakan, (4) praktik mandiri pembuatan handsanitizer non-alkohol berbasis TOGA yang dilakukan oleh para peserta didampingi tim PKM bersama mahasiswa, (5) umpan balik hasil kegiatanPKM pelatihan pembuatan handsanitizer non-alkohol dilakukan dengan cara menyebarkan lembarpenilaian keterampilan dan lembar angket peserta, (6) secara keseluruhan mitra peserta pelatihan yang dinilai oleh tim penilai PKM sudah dapat dikatakan memiliki keterampilan dalam membuat hand sanitizer non-alkoholdalam kategori baik dan sangat baik. Tim penilai PKM sepakat seluruh mitra memiliki ketrampilan:1) mencuci bersih daun sirih dan jeruk nipis dan 2) menyiapkan perasan buah jeruk nipis danmemasukkan ke dalam wadah. Sementara, aspek keterampilan lainnya mitra peserta pelatihandinilai masih beragam dari kategori antara baik dan sangat baik.
Several Compounds Isolated from Stem Bark of Kedoya (Dysoxylum gaudichaudianum (A. Juss.) Miq.) (Meliaceae) Tukiran Tukiran
Jurnal ILMU DASAR Vol 10 No 2 (2009)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (790.253 KB)

Abstract

Several compounds, p-hydroxyacetophenone, b-sitosterol and stigmasterol had been isolated from hexane and chloroform extracts of stem bark of kedoya (Dysoxylum gaudichaudianum (A. Juss.) Miq.) (Meliaceae) respectively. These structures had been established based on spectroscopic data (IR and NMR) and by comparison with spectroscopic data of related compounds that had been reported.
IMPROVEMENT OF SELF EFFICACY AND STUDENT LEARNING OUTCOMES USING ARGUMENT DRIVEN INQUIRY LEARNING MODEL Choirun Nikmah; Tukiran Tukiran; Harun Nasrudin
JURNAL PENDIDIKAN SAINS UNIVERSITAS MUHAMMADIYAH SEMARANG Vol 8, No 2 (2020): JURNAL PENDIDIKAN SAINS (JPS)
Publisher : Pendidikan Kimia Unimus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jps.8.2.2020.133-138

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This  research aimed  to to improve self efficacy and student learning outcomes on electrolyte and non electrolyte and non-electrolyte material using Argument Driven Inquiry (ADI) learning model. The test was applied to the 34 students of grade X-6 in Senior high school 7 of Surabaya. Development model of this teaching method used the three stages 4D model from Thiagarajan (define, design, develop). The application stage in the class used pre-experimental, pretest – posttest design. The evaluation used the self efficacy questionnaire, motivation questionnaire and pretest –posttest problems. The result found that the  increase of average students’ self efficacy was 0.6 and the average increase of motivation was 0.6. In other way, the average increase of learning result was 0.7 in high category. Based on the data analysis using ADI learning model can improve self efficacy and student learning outcomes.
GALLIC ACID: A PHENOLIC ACID AND ITS ANTIOXIDANT ACTIVITY FROM STEM BARK OF CHLOROFORM EXTRACTS OF SYZYGIUM LITORALE (BLUME) AMSHOFF (MYRTACEAE) Tukiran Tukiran; Fitriyatul Mahmudah; Nurul Hidayati; Kuniyoshi Shimizu
Molekul Vol 11, No 2 (2016)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (472.135 KB) | DOI: 10.20884/1.jm.2016.11.2.215

Abstract

A phenolic acid had been isolated from chloroform soluble fractions of a methanol extract of stem bark of Syzygium litorale, Fam. Myrtaceae. The structure of the isolated compound was elucidated and established as gallic acid through extensive spectroscopic studies (UV-Vis, FTIR, and NMR) and by comparison with literature data and authentic sample. This is the first report of the isolation of compound from this plant, although it has previously been found in Myrtaceae family such as S. aromaticum, S. cumini, S. polyanthum, S. cordatum, etc. The chloroform fraction, isolated compound, and vitamin C showed very strong antioxidant activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) with IC50 value of 23.2, 7.5, and 12.5 mg/mL, respectively.
Profile of Analytical Thinking Skills Through Inquiry-Based Learning in Science Subjects Alifia Suryatin Ramadani; Zainul Arifin Imam Supardi; Tukiran; Eko Hariyono
Studies in Learning and Teaching Vol. 2 No. 3 (2021): December
Publisher : Indonesia Approach Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46627/silet.v2i3.83

Abstract

The 2013 curriculum aims to form students who are ready to face the 21st century so that the 2013 curriculum is not only taught about aspects of knowledge but also aspects of skills. Thinking skills are the skills used in the 2013 curriculum, where one of the thinking skills students need is expertise in analytical thinking. These skills are necessary for science learning. Analytical thinking skills can be improved if the teacher trains them correctly, both from the learning model and learning strategies. This study examines learning models and learning tools that can improve analytical thinking skills. Learning based on inquiry learning is expected to improve students' analytical thinking skills. The findings of this study, it is known that inquiry-based models and tools can improve analytical thinking skills because they start from a problem. The problems given are then discussed with the group to find information that fits the situation and find ways to solve the problem nicely by conducting experiments or observations, then summing up the results obtained and communicating them well. Analytical thinking skills are closely related to problem-solving. So with analytical thinking skills, students will quickly identify and solve a problem.
Science Technology Engineering Arts Mathematics (STEAM) Approach for Learning Science in Junior High School Arum Kismawardani; Tukiran; Eko Hariyono
Studies in Learning and Teaching Vol. 3 No. 1 (2022): April
Publisher : Indonesia Approach Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46627/silet.v3i1.101

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This study aims to determine how the application of the STEAM approach to science learning in junior high school. The research was conducted by giving questionnaires to science subject teachers at the junior high school level in Surabaya, Sidoarjo, and several surrounding areas. Based on the results of the questionnaire given to the science teacher, it showed that 72% of the STEAM approach had been understood by the science teacher, 12% said they did not understand the STEAM approach and the remaining 16% answered doubtfully whether they understood the STEAM approach in science learning. However, only about 50% of science teachers who understand carry out learning using the STEAM approach. As many as 28% stated the lack of supporting articles for implementing the STEAM approach. Another result stated that 56% of teachers had difficulty in referencing learning tools with the STEAM approach which had to be adapted to school conditions and another 16% needed training to apply the STEAM approach to be applied in learning. Based on the results obtained, the largest percentage needed by teachers to help implement science learning using the STEAM approach is the need for learning tools. Therefore, STEAM-based learning tools really need to be developed, especially for the science teaching and learning process.
Co-Authors Ahmad Misbakhus Sururi Ahmad Rudi Setiawan Ahmad Rudi Setiawan Ali Imron Alifia Suryatin Ramadani Amalia Ruhana Amalia Ruhana, Amalia Andika Pramudya Wardana Andryan Dwisaksana Anggy Ayu Maharrany Anisa Kurnia Sari Anjani Fadia Putri Anjani Fadia Putri Arif Imam Subagyo Arum Kismawardani Budi Jatmiko Choirun Nikmah Cindy Ambarwati Danny Adi Kurniawan Dina Kartika Maharani Dini Attala Hefa Insyira Dody Tri Kurniawan Dody Tri Kurniawan E Eniswatin Elvira Ratna Aisa Erman Erman Eryantika Cipta Dewi Eryantika Cipta Dewi Fajrul Falah Fauzia Indah Sabila Fauzia Indah Sabila Fauzia Indah Sabila Fida Rachmadiarti Fitriyatul Mahmudah Frisca Nadya Safitri Frisca Nadya Safitri Handini Zahrah Firdausi Hariyono, Eko Harun Nasrudin Harun Nasrudin Harun Nasrudin I GUST MADE SANJAYA Idah Dianawati Ika Fatmawati Pramasari Imas Nur Mazidah Irene Cornelia Constanty Irene Cornelia Constaty Kuniyoshi Shimizu Kuniyoshi Shimizu Kuniyoshi Shimizu Kusumawati Dwiningsih Leny Yuanita Leny Yuanita M. Raihan Mauren Gita Miranti Mohamad Nur Muhammad Rafly Aditya Firmansyah Nadiah Armadanti Salma Najwa Salsabila Hakim Nita Kusumawati Noera Wahdaniyah Norviria Tsalasatin Apriliani Nuniek Herdyastuti Nuri Yuliani Yuliani Nurkhasanah Nurkhasanah Nurul Hidajati Nurul Hidayati Nurul Hidayati Nurul Hidayati Nurul Hidayati P Prabowo Pungky Dilaka Putri Ratih Dewi Saputri Ratih Yuniastri Ratih Yuniastri Renita Meilasari Rinaningsih Rinaningsih Rizdana Galih Pambudi Rizka Tazky Amalia Rizq Rachmad Ramiizah Robiatusy Syifaiyah Rohmah Primadani Rohmatus Syafiah Rudiana Agustini Safira Madaniyah Safira Madaniyah Saidah Saidah Saiyidah Mahtari Sari Edi Cahyaningrum Shela Insanul Hikmah Shifa Fauziyah Shifa Fauziyah Sifak Indana Sin War Naw Sin War Naw Sri Hidayati Syarief Sumarni Sumarni Sunu Kuntjoro Suyatno Sutoyo Suyatno Sutoyo Suyatno Sutoyo Suyatno Suyatno Suyatno Suyatno Suyatno Suyatno Suyono Suyono Syananda Zahra Fadila Syananda Zahra Fadila Teguh Hari Sucipto Teguh Hari Sucipto, Teguh Hari Titik Taufikurohmah Wahono Widodo Wahono Widodo Woro Setyarsih Yunus Yunus ZAINUL ARIFIN IMAM SUPARDI