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All Journal Jurnal Natural Buletin Pengabdian
Tedy Kurniawan Bakri
Pharmacy Department, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Education Energy Engineering Immunology & microbiology Neuroscience Physics Public Health Social Sciences

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FORMULATION DOSAGE FORM OF TABLET CONTAINING KEPEL LEAF EXTRACT (Stelechocarpus burahol (Blume) Hook.f & Thomson) AS AN ANTIMICROBIAL AGENTS Hilda Maysarah; Meutia Faradilla; Tedy Kurniawan Bakri; Misrahanum Misrahanum
Jurnal Natural Volume 19 Number 2, June 2019
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (373.739 KB) | DOI: 10.24815/jn.v19i2.12151

Abstract

Pharmaceutical dosage form that contains herbal materials has been developed in order to make it easy to consume. Tablet is one of pharmaceutical dosage form that generally used. A formulation and antimicrobial test of tablet containing extract of Kepel leaf with different concentration of diluents, binders, and disintegrants has been studied. The evaluation test showed that formulation consist of  25 % of Kepel leaf extract, 64.5 % of avicel PH 102, 2 % of PVP, 7 % of amprotab, 0.5 % of aerosil, and 1 % of talcum are better than the others. The experimental method used in this study was wet granulation. From the result of the mass granulation evaluation, it was obtain that speed flow without vibration was 2.53 second, with vibration was 2.83 second, bulk density was 0.329 g/mL, taped density was 0.376 g/mL and compressibility was 12.65 %. The result of tablet evaluation obtained that the average weight was 498 mg, with the average hardness was 4 kg/cm2 and disintegration time was 2.36 minutes. Antimicrobial test showed that in the concentration of 50 mg/mL, had average inhibitory diameter against S. aureus of 12.96 mm, P. aeruginosa 12.7 mm, and against B. subtilis was 12.53 mm. Whereas, concentration of 62.5 mg/mL had average inhibitory diameter against S. aureus was 13.5 mm, P. aeruginosa was 13.56 mm, and against B. subtilis was 13.43 mm. Both concentrations did not have antimicrobial activity against E.coli. 
FORMULATION DOSAGE FORM OF TABLET CONTAINING KEPEL LEAF EXTRACT (Stelechocarpus burahol (Blume) Hook.f & Thomson) AS AN ANTIMICROBIAL AGENTS Hilda Maysarah; Meutia Faradilla; Tedy Kurniawan Bakri; Misrahanum Misrahanum
Jurnal Natural Volume 19 Number 2, June 2019
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v19i2.12151

Abstract

Pharmaceutical dosage form that contains herbal materials has been developed in order to make it easy to consume. Tablet is one of pharmaceutical dosage form that generally used. A formulation and antimicrobial test of tablet containing extract of Kepel leaf with different concentration of diluents, binders, and disintegrants has been studied. The evaluation test showed that formulation consist of  25 % of Kepel leaf extract, 64.5 % of avicel PH 102, 2 % of PVP, 7 % of amprotab, 0.5 % of aerosil, and 1 % of talcum are better than the others. The experimental method used in this study was wet granulation. From the result of the mass granulation evaluation, it was obtain that speed flow without vibration was 2.53 second, with vibration was 2.83 second, bulk density was 0.329 g/mL, taped density was 0.376 g/mL and compressibility was 12.65 %. The result of tablet evaluation obtained that the average weight was 498 mg, with the average hardness was 4 kg/cm2 and disintegration time was 2.36 minutes. Antimicrobial test showed that in the concentration of 50 mg/mL, had average inhibitory diameter against S. aureus of 12.96 mm, P. aeruginosa 12.7 mm, and against B. subtilis was 12.53 mm. Whereas, concentration of 62.5 mg/mL had average inhibitory diameter against S. aureus was 13.5 mm, P. aeruginosa was 13.56 mm, and against B. subtilis was 13.43 mm. Both concentrations did not have antimicrobial activity against E.coli. 
Education on clean and healthy living behavior and wise use of medicine at the Al-Qur'an Tahfidz Boarding School Jami' Baitusshalihin [Edukasi perilaku hidup bersih dan sehat serta bijak menggunakan obat di Pesantren Tahfidz Al-Qur'an Jami' Baitusshalihin] Tedy Kurniawan Bakri; S Suryawati; Hijra Novia Suardi; Heru Fahlevi; Shylvana Adella; Rudi Dharma; Cut Melda Meriyana; R Raihanah
Buletin Pengabdian Bulletin of Community Services Vol 4, No 3 (2024): Bull. Community. Serv.
Publisher : The Institute for Research and Community Services (LPPM) Universitas Syiah Kuala (USK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/bulpen.v4i4.41329

Abstract

A healthy and clean environment can be created starting from self-awareness and the surrounding community. A clean environment fosters a healthy life and is free from various diseases. Clean and Healthy Living Behavior (PHBS) is an action to prevent the occurrence of diseases and improve health levels. Disease disorders caused by poor sanitation in the boarding school environment certainly require further treatment, one of which is by consuming certain drugs. The steps in obtaining, using, storing, and disposing of drugs need to be known by students in order to maximize the healing of their illnesses. The purpose of this service is to increase awareness among students about the importance of maintaining personal and environmental hygiene, as well as to provide the right knowledge about the use of drugs. The methods used in this community service include lectures, discussions, educational videos, and simulations. The results of this community service indicate an increase in the understanding and knowledge of students regarding clean living patterns. Boarding school managers also gained a better understanding of the importance of proper sanitation in the boarding school environment and how to use drugs properly and correctly. In conclusion, there is an increase in students' understanding of clean-living patterns and knowledge of how to use drugs appropriately.
Co-Authors Azizah Vonna Azizah Vonna Cut Melda Meriyana Fitrah Sari Fitrah Sari Heru Fahlevi Hijra Novia Suardi Hilda Maysarah Lydia Septa Desiyana Meutia Faradilla Misrahanum Misrahanum Nanda Fitria R Raihanah Raihanul Akmal Rudi Dharma S Suryawati Shylvana Adella