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All Journal Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) e-Jurnal Inovasi Pembelajaran Sekolah Dasar e-Jurnal Inovasi Pembelajaran Sekolah Dasar
Nurhasni Hasan
Pharmacy Faculty of Hasanuddin University
Computer Science & IT Education Languange, Linguistic, Communication & Media Library & Information Science Mathematics Medicine & Pharmacology Social Sciences Other

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ISOLASI DAN IDENTIFIKASI ETHYL P-METHOXYCINNAMATE (EPMC) DARI RIMPANG KENCUR (Kaempheria galanga) SEBAGAI KANDIDAT SENYAWA ANTIKANKER Hasan, Nurhasni; Sitti Nur Fatimah; Anugerah; Muhammad Raihan; Subehan; Apon Zaenal Mustopa; Herman Irawan; Jabal Rahmat Haedar; Habibie
Majalah Farmasi dan Farmakologi Vol. 27 No. 3 (2023): MFF
Publisher : Faculty of Pharmacy, Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/mff.v27i3.28335

Abstract

Indonesia kaya akan keanekargaman tanaman obat. Salah satunya adalah rimpang kencur atau Kaempferia galanga L. Tanaman ini memiliki potensi besar sebagai sumber penting senyawa bioaktif yang dapat mendukung pengembangan obat-obatan alami serta mendorong penelitian lebih lanjut dalam bidang farmakologi dan pengobatan. Kaempferia galanga sendiri telah diteliti mengandung beragam senyawa yang dapat dimanfaatkan untuk berbagai aktivitas farmakologi salah satunya adalah antikanker. Salah satu komponen senyawa yang dimiliki oleh Kaempferia galanga  yang dapat digunakan sebagai antikanker adalah etil p-methoxycinnamate (EPMC). Penelitian ini bertujuan untuk mengisolasi dan mengidentifikasi senyawa EPMC untuk memperoleh hasil isolasi yang maksimal dengan kadar EPMC yang tinggi. Metode isolasi EPMC dari tanaman kencur menggunakan soxhlet sebagai alat ekstraksi. Identifikasi dan penentuan kadar senyawa diperoleh menggunakan evaluasi KLT, GC-MS, NMR, HPLC dan Spektrofotometri UV-Vis. Hasil identifikasi menunjukkan isolat dari Kaempheria galanga merupakan senyawa ethyl p-methoxycinnamate dengan berat molekul 206 dan persentase kadar EPMC menunjukkan kadar yang tinggi baik menggunakan HPLC  maupun spektrofotometer UV-Vis, dimana kadar EPMC dalam isolat didapatkan sebesar 90,40 ± 3,62 %, dan 91,29 ± 3,66 %. Sedangkan untuk kadar pada ekstrak metanol Kaempheria galanga adalah 49,57 ± 0,63 % dan 40,61± 0,25% berdasarkan hasil HPLC dan spektrofotometer UV-Vis.  Berdasarkan hasil tersebut dapat disimpulkan bahwa metode isolasi EPMC dari tanaman kencur (Kaempferia galanga) menggunakan soxhlet sebagai alat ekstraksi memberikan rendemen ekstrak dan rendemen isolat yang tinggi.
Pengaruh Strategi Polya terhadap hasil belajar penyelesaian soal cerita pecahan dalam masalah perbandingan dan skala di kelas V SD gugus X kecamatan koto tangah kota padang hasan, Nurhasni
e-Jurnal Inovasi Pembelajaran Sekolah Dasar Vol 6, No 2 (2018): (Mei-Agustus) e-JIPSD
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/e-jipsd.v6i2.3701

Abstract

This research is motivated by the use of inappropriate learning strategies in the learning of fraction story problems in the problem of comparison and scale that results in low student learning outcomes. This study aims to determine the effect of Polya Strategy on Learning Outcomes in Solving Fraction Story Problems in Comparative and Scale Problems in Class V SD of Cluster X in Koto Tangah District, Padang City. This type of research is quantitative in the form of quasy experiment design. The design used by the nonequivalent posttest-only control group design. The study was conducted at SDN 15 Padang Sarai, Padang City. Based on the results of the posttest obtained the average learning outcomes of solving story problems in control class students who apply conventional learning is 53.9. And the average value of learning outcomes in solving the story questions for the experimental class students by applying the Polya strategy is 72.4. Based on the results of hypothesis testing using the t-test on the real level α = 0.05 obtained t_count = 2.84 and ttable = 1.997, so that t_count> t table then Ha in this study was accepted and rejected H0. It can be concluded that Polya's strategy influences learning outcomes in solving fractional story problems in terms of comparison and scale in class V SD gugus X Kecataman Koto Tangah city of Padang.
Pengaruh Strategi Polya terhadap hasil belajar penyelesaian soal cerita pecahan dalam masalah perbandingan dan skala di kelas V SD gugus X kecamatan koto tangah kota padang hasan, Nurhasni
e-Jurnal Inovasi Pembelajaran Sekolah Dasar Vol 6, No 2 (2018): (Mei-Agustus) e-JIPSD
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/e-jipsd.v6i2.3701

Abstract

This research is motivated by the use of inappropriate learning strategies in the learning of fraction story problems in the problem of comparison and scale that results in low student learning outcomes. This study aims to determine the effect of Polya Strategy on Learning Outcomes in Solving Fraction Story Problems in Comparative and Scale Problems in Class V SD of Cluster X in Koto Tangah District, Padang City. This type of research is quantitative in the form of quasy experiment design. The design used by the nonequivalent posttest-only control group design. The study was conducted at SDN 15 Padang Sarai, Padang City. Based on the results of the posttest obtained the average learning outcomes of solving story problems in control class students who apply conventional learning is 53.9. And the average value of learning outcomes in solving the story questions for the experimental class students by applying the Polya strategy is 72.4. Based on the results of hypothesis testing using the t-test on the real level α = 0.05 obtained t_count = 2.84 and ttable = 1.997, so that t_count> t table then Ha in this study was accepted and rejected H0. It can be concluded that Polya's strategy influences learning outcomes in solving fractional story problems in terms of comparison and scale in class V SD gugus X Kecataman Koto Tangah city of Padang.
Co-Authors Anugerah APON ZAENAL MUSTOPA Habibie Herman Irawan Jabal Rahmat Haedar Muhammad Raihan Sitti Nur Fatimah Subehan