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All Journal Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JOURNAL SPORT AREA Jurnal Akutansi Manajemen Ekonomi Kewirausahaan (JAMEK)
Habibie
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Economics, Econometrics & Finance Medicine & Pharmacology Other

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ISOLASI DAN IDENTIFIKASI ETHYL P-METHOXYCINNAMATE (EPMC) DARI RIMPANG KENCUR (Kaempheria galanga) SEBAGAI KANDIDAT SENYAWA ANTIKANKER Hasan, Nurhasni; Sitti Nur Fatimah; Anugerah; Muhammad Raihan; Subehan; Apon Zaenal Mustopa; Herman Irawan; Jabal Rahmat Haedar; Habibie
Majalah Farmasi dan Farmakologi Vol. 27 No. 3 (2023): MFF
Publisher : Faculty of Pharmacy, Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/mff.v27i3.28335

Abstract

Indonesia kaya akan keanekargaman tanaman obat. Salah satunya adalah rimpang kencur atau Kaempferia galanga L. Tanaman ini memiliki potensi besar sebagai sumber penting senyawa bioaktif yang dapat mendukung pengembangan obat-obatan alami serta mendorong penelitian lebih lanjut dalam bidang farmakologi dan pengobatan. Kaempferia galanga sendiri telah diteliti mengandung beragam senyawa yang dapat dimanfaatkan untuk berbagai aktivitas farmakologi salah satunya adalah antikanker. Salah satu komponen senyawa yang dimiliki oleh Kaempferia galanga  yang dapat digunakan sebagai antikanker adalah etil p-methoxycinnamate (EPMC). Penelitian ini bertujuan untuk mengisolasi dan mengidentifikasi senyawa EPMC untuk memperoleh hasil isolasi yang maksimal dengan kadar EPMC yang tinggi. Metode isolasi EPMC dari tanaman kencur menggunakan soxhlet sebagai alat ekstraksi. Identifikasi dan penentuan kadar senyawa diperoleh menggunakan evaluasi KLT, GC-MS, NMR, HPLC dan Spektrofotometri UV-Vis. Hasil identifikasi menunjukkan isolat dari Kaempheria galanga merupakan senyawa ethyl p-methoxycinnamate dengan berat molekul 206 dan persentase kadar EPMC menunjukkan kadar yang tinggi baik menggunakan HPLC  maupun spektrofotometer UV-Vis, dimana kadar EPMC dalam isolat didapatkan sebesar 90,40 ± 3,62 %, dan 91,29 ± 3,66 %. Sedangkan untuk kadar pada ekstrak metanol Kaempheria galanga adalah 49,57 ± 0,63 % dan 40,61± 0,25% berdasarkan hasil HPLC dan spektrofotometer UV-Vis.  Berdasarkan hasil tersebut dapat disimpulkan bahwa metode isolasi EPMC dari tanaman kencur (Kaempferia galanga) menggunakan soxhlet sebagai alat ekstraksi memberikan rendemen ekstrak dan rendemen isolat yang tinggi.
Analisis Komparatif Rasio Likuiditas, Aktivitas, Solvabilitas dan Profitabiltas PT.Sariguna Primatirta dengan Industri AMDK 2020-2024 Paramadharma, Harnandito; Habibie; Kurnia Rambe; Sri Hermuningsih
Jurnal Akutansi Manajemen Ekonomi Kewirausahaan (JAMEK) Vol 5 No 2 (2025): Edisi Mei 2025
Publisher : Forum Kerjasama Pendidikan Tinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jamek.v5i2.2010

Abstract

This study compares the financial performance of PT. Sariguna Primatirta (CLEO) to its competitors (ADES & MYOR) in the bottled drinking water (AMDK) business in Indonesia from 2020 to 2024. The analysis methodologies employed include the calculation of liquidity, activity, solvency, and profitability ratios, as well as trend analysis, stability tests (standard deviation), and benchmarking. The study's findings show that while PT. Sariguna Primatirta's profitability and activity performance are high, company has a low liquidity ratio. In comparison to the industry/competitors, PT. Sariguna Primatirta's liquidity is lower, the activity ratio is superior in the accounts receivable and inventory turnover ratios, but the accounts receivable turnover decreases, the solvency ratio is stable but the trend is below the industry, and the profitability ratio is above the industry average.
Why do female athletes face harassment and bullying? A mixed-methods study Ekowati; Setiawan, Edi; Habibie; Abdullah, Khairul Hafezad; Gazali, Novri; Hofmeister, Martin; Németh, Zsolt
Journal Sport Area Vol 8 No 1 (2023): April
Publisher : UIR Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25299/sportarea.2023.vol8(1).11583

Abstract

The phenomenon of escalating harassment and bullying of female athletes in sports demonstrates that there is a gap and urgency for further scrutiny. This study aims to reveal harassment and bullying cases against female athletes in sports. This study applied a mixed method. Participants in this study were athletes in several sports organizations at the University of Islam 45 Bekasi (n = 30). A questionnaire was used as the quantitative research instrument to measure harassment and bullying in athletes, while in-depth interviews were used as the qualitative research instrument. Quantitative statistical analysis used IBM SPSS to find frequency and percentage, and qualitative analysis used thematic analysis. The quantitative research results significantly proved that all participants often experience harassment and bullying, with the highest rate occurring in gymnastics, swimming, volleyball, and soccer. While the results of the qualitative research showed that all participants had experiences or stories about harassment and bullying, the causal factors included the conditions of the training environment, athletes' clothes, attitudes, and the knowledge of coaches and athletes. In addition, participants stated that harassment and bullying negatively impact their health and psychological aspects. As a result, we emphasize that incidents of harassment and bullying occur frequently in female athletes while they are participating in sports. It is expected that this research could provide information and understanding to all sports practitioners in Indonesia and all countries in the world that harassment and bullying are very dangerous and immoral and must be handled as soon as possible by providing strict rules.
Co-Authors Abdullah, Khairul Hafezad Anugerah APON ZAENAL MUSTOPA Edi Setiawan Ekowati Gazali, Novri Harnandito Paramadharma, Harnandito Herman Irawan Hofmeister, Martin Jabal Rahmat Haedar Kurnia Rambe Muhammad Raihan Németh, Zsolt Nurhasni Hasan Sitti Nur Fatimah Sri Hermuningsih Subehan