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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Kimia (Journal of Chemistry) JURNAL KIMIA SAINS DAN APLIKASI Jurnal Sains Materi Indonesia KOVALEN: Jurnal Riset Kimia Indonesia Chimica Acta Alotrop Jurnal Pendidikan dan Ilmu Kimia Dinamisia: Jurnal Pengabdian Kepada Masyarakat Jambura Journal of Chemistry Menara Perkebunan RANDANG TANA - Jurnal Pengabdian Masyarakat Jurnal Farmamedika (Pharmamedica Journal) Jurnal Ilmu Kesehatan Jurnal Inovasi Teknik Kimia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Prosiding SIMKESNAS Jurna Beta Kimia Jurnal Sains dan Kesehatan Jurnal Penelitian dan Pengabdian Masyarakat
Gusti Ayu Dewi Lestari
Program Studi S1 Farmasi, Sekolah Tinggi Farmasi Mahaganesha, Jalan Tukad Barito No 57 Denpasar Bali, Indonesia
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PENGUJIAN KUALITAS MINYAK KEMIRI (Aleurites moluccana) YANG DIHASILKAN DARI PROSES RENDERING DAN PENGEPRESAN MEKANIK DARI PRODUSEN ‘MINYAK KEMIRI JERNIH’ Ni Made Widayanti; Gusti Ayu Dewi Lestari; Kadek Duwi Cahyadi; Ni Ketut Esati
Jurnal Inovasi Teknik Kimia Vol 9, No 4 (2024)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v9i4.11873

Abstract

Kemiri (Aleurites moluccana) adalah tanaman yang banyak dimanfaatkan oleh masyarakat. Bagian kemiri yang sering dimanfaatkan oleh masyarakat adalah bagian biji yang digunakan untuk memproduksi minyak kemiri. Minyak kemiri diketahui memiliki berbagai manfaat, seperti menyuburkan rambut dan mengobati masalah kulit. Penelitian ini bertujuan untuk menganalisis mutu dan kandungan asam lemak pada minyak kemiri yang dihasilkan melalui dua metode ekstraksi, yaitu dengan proses rendering dan proses pengepresan mekanik. Analisis mutu minyak kemiri dilakukan berdasarkan parameter Standar Nasional Indonesia (SNI 01-4462-1998) yang meliputi uji organoleptis, bobot jenis, indeks bias, kadar air, bilangan penyabunan, bilangan iod, dan uji asam lemak bebas. Selain itu, dilakukan pula analisis terhadap komposisi asam lemak menggunakan GC-MS (Gas Chromatography Mass Spectrofotometry) untuk mengidentifikasi dan mengukur proporsi asam lemak tak jenuh yang terdapat dalam minyak kemiri.  Hasil penelitian menunjukkan bahwa minyak kemiri yang diekstraksi melalui kedua metode tersebut memenuhi standar mutu yang ditetapkan oleh SNI. Minyak kemiri yang diekstraksi dengan metode pengepresan mekanik memiliki kualitas yang lebih baik dibandingkan dengan metode rendering, ditunjukkan oleh nilai bilangan asam dan kadar air yang lebih rendah. Kedua metode tersebut menghasilkan minyak kemiri dengan kandungan utama asam lemak tak jenuh yaitu asam linoleat 29,76% untuk minyak kemiri dari proses rendering dan 50,92% untuk minyak kemiri dari proses pengepresan mekanik
PENGGUNAAN BIOREDUKTOR EKSTRAK AIR DAUN SIRSAK (Annona mucirata L.) UNTUK FITOSINTESIS NANOPARTIKEL PERAK (NPAg) DENGAN BERBAGAI VARIASI RASIO CAMPURAN Gusti Ayu Dewi Lestari; Ni Wayan Nieskajanti Kedeh Van Kempen; Kadek Duwi Cahyadi; Ni Ketut Esati
Jurnal Inovasi Teknik Kimia Vol 9, No 3 (2024)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v9i3.10258

Abstract

Nanopartikel adalah ilmu yang mempelajari mengenai ukuran partikel antara 1-100 nm. Beberapa jenis logam yang dapat disintesis menjadi nanopartikel menggunakan metode fitosintesis yaitu emas, perak, paladium, platinum, besi, zink, dan logam dioksida. Salah satu logam yang paling sering disintesis menjadi nanopartikel adalah nanopartikel perak. Karakterisasi pembentukan nanopartikel perak dapat diidentifikasi menggunakan spektrofotometer UV-Vis, TEM, SEM-EDX dan PSA. Tujuan dilakukan penelitian ini yaitu untuk mengoptimalkan rasio campuran antara bioreduktor ekstrak air daun sirsak dengan larutan AgNO3 sehingga menghasilkan ukuran nanopartikel perak terkecil dan stabil. Tahap penelitian ini meliputi skrining fitokimia ekstrak air daun sirsak, sintesis nanopartikel perak dengan rasio campuran antara ekstrak air daun sirsak dengan larutan AgNO3 1 mM adalah 1:9; 3:7 dan 5:5, dan karakterisasi nanopartikel perak. Hasil spektrofotometer UV-Vis menunjukkan pembentukan NPAg pada rasio campuran 1:9 dengan panjang gelombang maksimum 405 nm. Hasil SEM-EDX menunjukkan serbuk NPAg yang cenderung menggumpal dan atom Ag terdeteksi pada 2,983 keV. Hasil TEM menunjukkan NPAg berbentuk bulat tidak beraturan dan hasil PSA menunjukkan ukuran NPAg diperoleh 39,31 nm.
PENGUJIAN KUALITAS MINYAK KEMIRI (Aleurites moluccana) YANG DIHASILKAN DARI PROSES RENDERING DAN PENGEPRESAN MEKANIK DARI PRODUSEN ‘MINYAK KEMIRI JERNIH’ Ni Made Widayanti; Gusti Ayu Dewi Lestari; Kadek Duwi Cahyadi; Ni Ketut Esati
Jurnal Inovasi Teknik Kimia Vol. 9 No. 4 (2024)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v9i4.12521

Abstract

Kemiri (Aleurites moluccana) adalah tanaman yang banyak dimanfaatkan oleh masyarakat. Bagian kemiri yang sering dimanfaatkan oleh masyarakat adalah bagian biji yang digunakan untuk memproduksi minyak kemiri. Minyak kemiri diketahui memiliki berbagai manfaat, seperti menyuburkan rambut dan mengobati masalah kulit. Penelitian ini bertujuan untuk menganalisis mutu dan kandungan asam lemak pada minyak kemiri yang dihasilkan melalui dua metode ekstraksi, yaitu dengan proses rendering dan proses pengepresan mekanik. Analisis mutu minyak kemiri dilakukan berdasarkan parameter Standar Nasional Indonesia (SNI 01-4462-1998) yang meliputi uji organoleptis, bobot jenis, indeks bias, kadar air, bilangan penyabunan, bilangan iod, dan uji asam lemak bebas. Selain itu, dilakukan pula analisis terhadap komposisi asam lemak menggunakan GC-MS (Gas Chromatography Mass Spectrofotometry) untuk mengidentifikasi dan mengukur proporsi asam lemak tak jenuh yang terdapat dalam minyak kemiri. Hasil penelitian menunjukkan bahwa minyak kemiri yang diekstraksi melalui kedua metode tersebut memenuhi standar mutu yang ditetapkan oleh SNI. Minyak kemiri yang diekstraksi dengan metode pengepresan mekanik memiliki kualitas yang lebih baik dibandingkan dengan metode rendering, ditunjukkan oleh nilai bilangan asam dan kadar air yang lebih rendah. Kedua metode tersebut menghasilkan minyak kemiri dengan kandungan utama asam lemak tak jenuh namun memiliki kadar yang berbeda yaitu asam linoleat 29,76% untuk minyak kemiri dari proses rendering dan 50,92% untuk minyak kemiri dari proses pengepresan mekanik”
BIOSINTESIS NANOPARTIKEL PERAK MENGGUNAKAN EKSTRAK AIR DAUN KECEMCEM (Spondias pinnata (L.f) Kurz.) DENGAN VARIASI KONSENTRASI EKSTRAK DAN SUHU SINTESIS Ngurah Wijaya Putra; Gusti Ayu Dewi Lestari
ALOTROP Vol. 8 No. 2 (2024): Alotrop 2024
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v8i2.37978

Abstract

This research aims to synthesize silver nanoparticles using various variations in extract concentration and synthesis temperature to produce the smallest and most stable silver nanoparticle. Step of this research are phytochemical screening of kecemcem leaf water extract, synthesis of silver nanoparticles with an extract concentration of 0.5; 0.75 and 1% and synthesis temperature 25; 40 and 60⁰C, and characterization of silver nanoparticles. The results of the UV-Vis spectrophotometer showed the formation of NPAg with a maximum wavelength of 420 nm. SEM and TEM results show that NPAg powder tends to clump and has an irregular round shape. PSA results show that the smallest size of NPAg is 30.55 nm with a PdI of 0.497. XRD results show that the crystal size of the synthesized NPAg is 0.23 nm.
Biosynthesis of silver nanoparticles (AgNPs) from coconut leaf extract and their antifungal activity against Ganoderma boninense mycelia Gusti Ayu Dewi Lestari; I Gusti Ayu Made Megayanti; Komang Ayu Astuti Maharani; Ni Wayan Nieskajanti Kedeh Van Kempen
Menara Perkebunan Vol. 92 No. 2 (2024): 92(2), 2024
Publisher : INDONESIAN OIL PALM RESEARCH INSTITUTE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22302/iribb.jur.mp.v92i2.586

Abstract

Basal stem rot disease caused by Ganoderma is a major problem in palm cultivation in Indonesia, so an appropriate solution is needed to overcome this problem. One of the solutions that can be applied is through silver nanoparticles. Synthesis of silver nanoparticles can use coconut leaves as a source of flavonoids. Flavonoids are one of the phenolic compounds that are widely used in the process of synthesizing silver nanoparticles. Flavonoid compounds have a hydroxyl group (OH), which can be reduced by donating electrons to the Ag+ ion from AgNO3 to Ag0. This research aims to synthesize silver nanoparticles (AgNPs) using coconut leaf water extract and its assessment as an antifungal for Ganoderma boninense. Silver nanoparticles were synthesized by mixing coconut leaf extract in 1 mM of AgNO3 solution with a ratio of 1:9 (v/v). The concentrations of coconut leaf water extract were 1% and 3% with a heating temperature of 60°C. Silver nanoparticles were characterized using a UV-Vis spectrophotometer, PSA, FTIR, TEM, and SEM-EDS. The AgNPs had a maximum wavelength of 430 nm, with morphologies like a ball, triangle, and square, a mass percentage of Ag of 51.77%, smallest particle size of 63.29 nm, PdI value of 0.3361, and a zeta potential of -16.98 mV. The FTIR spectra show that the functional group that plays a role in the reduction process is the –OH group. The antifungal activity assay produced the highest percentage of colony growth inhibition (68.37%) at a concentration of 4.9 ppm in the 10-day incubation.
PENYULUHAN KURATIF BEKERJASAMA DENGAN PUSKESMAS DESA SANGEH DALAM PEMERIKSAAN DAN EDUKASI PENATALAKSANAAN HIPERTENSI KEPADA MASYARAKAT DI POSYANDU BANJAR TEGAL GERANA DESA SANGEH Kusuma, Luh Adi; Kurnianta, Putu Dian Marani; Lestari, Gusti Ayu Dewi; Pramesti, Ni Komang Ayu Dyah; Wati, Ni Ketut Sindia; Dewi, Ni Putu Nita Lusiana; Pratiwi, Ni Kadek Saskya; Abiansyah, Faisal Oktaviani Pratama; Poa, Patricia Novica Dua
JPMUJ Vol. 3 No. 3 (2025): SEMUA ARTIKEL TERBIT SECARA ONLINE
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat UIKA Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/jpmuj.v3i3.2869

Abstract

Hypertension is one of the most prevalent non-communicable diseases and a major contributor to morbidity and mortality rates in Indonesia. In Banjar Tegal Gerana, Sangeh Village, hypertension cases remain high, while public awareness regarding its management is relatively low. Therefore, a community service program was carried out in the form of curative health education aimed at increasing public knowledge about hypertension. This activity was conducted collaboratively between pharmacy students and healthcare professionals from the local public health center (Puskesmas). A total of 35 participants attended the session, which covered topics including the definition, risk factors, symptoms, complications, types of antihypertensive drugs, and how to measure blood pressure independently. A structured questionnaire was used as an instrument to assess knowledge through pretest and posttest evaluations. Data analysis using the Shapiro-Wilk test confirmed that the data were normally distributed (p > 0.05), allowing for further analysis using a Paired T-Test, which revealed a significant difference between pretest and posttest scores (p < 0.001). These findings indicate that the educational intervention effectively improved participants' knowledge. This program demonstrates that collaborative education between students and health professionals can serve as an effective promotive and preventive strategy for enhancing public awareness and independent management of hypertension.
Association Analysis of Complications, Number of Drugs, and Medication Adherence in End-Stage Renal Disease Patients Undergoing Hemodialysis Ratnasari, Pande Made Desy; Yuliawati, Agustina Nila; Lestari, Gusti Ayu Dewi; Andaresta, Ni Luh Putu Silvia
Jurnal Ilmu Kesehatan Vol 11 No 2 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i2.3809

Abstract

Hemodialysis (HD) in its implementation is reported to cause complications. Complications may cause the patients to receive >3 types of drugs and decrease their medication adherence. This study aimed to analyze the association between the number of complications and the number of drugs, and the association between the number of drugs with medication adherence in End-Stage Renal Disease (ESRD) patients. This research was conducted at the private hospital Denpasar in March-May 2021 with a cross-sectional design involving 93 respondents. The purposive sampling technique was used according to inclusion criteria (ESRD patients with complications, undergoing HD at least twice a week, signing informed consent) and exclusion criteria (having poor or unstable health, unable to communicate well). The research instrument used was a questionnaire (ESRD-AQ). The Mann-Whitney test and Kendall tau-b test were used to analyze the association in this study. The results showed that the majority of patients were <65 years old (83.9%), male (66.7%), 35.5% high school education, still working (51.6%), and long of diagnosed with ESRD <5 years (77%). The average patient had ≥2 complications (81.72%) and 80.64% received 1-6 types of drugs with high levels of medication adherence (67.74%). There was an association between the number of complications and the number of drugs (p=0.026) and the association between the number of drugs and medication adherence (p=0.023) with a weak correlation (r=-0,227). This indicates that complications can affect the number of drugs consumed and indirectly also affect the medication adherence of ESRD patients.
Analysis of the Antioxidant Activity of Strawberry Kombucha using the UV–Vis Spectrophotometric Method Esati, Ni Ketut; Lestari, Gusti Ayu Dewi; Griadnyana, Ida Bagus Nanda
Jurnal Beta Kimia Vol 5 No 2 (2025): Volume 5 Issue 2, November 2025
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jbk.v5i2.24419

Abstract

The development of modern lifestyles, which tend to favor instant foods and beverages, has increased the risk of degenerative diseases associated with oxidative stress. This condition has driven the demand for foods and beverages rich in antioxidants. Kombucha is a fermented beverage recognized for its probiotic and antioxidant properties, while strawberries are rich in natural antioxidant compounds. The combination of these two components has the potential to produce a functional beverage beneficial to health, particularly as a source of antioxidants. Therefore, this study aimed to determine the effect of fermentation duration on the antioxidant activity of strawberry kombucha and to identify the optimal fermentation duration for achieving the highest antioxidant activity. This study employed a quantitative research design using a laboratory experimental method. Strawberry kombucha was prepared from a mixture of fresh strawberries, water, granulated sugar, SCOBY starter solution, and SCOBY, followed by fermentation for 7, 10, and 13 days. Antioxidant activity was evaluated using the UV-Vis spectrophotometric method with DPPH reagent. The results demonstrated that fermentation duration significantly affected the antioxidant activity of strawberry kombucha. The highest antioxidant activity was achieved on day 10, with an IC50​ value of 24.69 ppm, which was categorized as very strong antioxidant activity. Fermentation on day 13 resulted in an IC50​ value of 30.69 ppm, which also fell within the very strong category, whereas fermentation on day 7 produced an IC50​ value of 74.38 ppm, categorized as strong antioxidant activity. Therefore, a fermentation duration of 10 days was identified as the optimal condition for producing the highest antioxidant activity. The findings of this study are expected to contribute to the development of beverage formulations rich in antioxidant compounds.
Co-Authors Abiansyah, Faisal Oktaviani Pratama Agustina Nila Yuliawati Andaresta, Ni Luh Putu Silvia Antariksa, Najwa Kusuma Putri B. Ankamwar Balqish Fathoum Medinna Dewi, Ni Putu Nita Lusiana Duwi Cahyadi, Kadek Esati, Ni Ketut Griadnyana, Ida Bagus Nanda Gusti Ayu Putu Prima Purnamasari I Gusti Ayu Made Megayanti I Putu Eka Budiarta Intan Wahyuni, Pande Made Iryanti Eka Suprihatin Iryanti Eka Suprihatin James Sibarani James Sibarani Jawa La, Elisabeth Oriana Jessica Sanchez Anggraini K. D. Cahyadi Kadek Duwi Cahyadi Kadek Duwi Cahyadi Kadek Duwi Cahyadi Kadek Duwi Cahyadi Komang Ayu Astuti Maharani Kunti Sri Panca Dewi, I Gusti Ayu Kusuma, Luh Adi Ngurah Wijaya Putra Ni Made Widayanti Ni Made Widayanti Ni Wayan Nieskajanti Kedeh Van Kempen Ni Wayan Nieskajanti Kedeh Van Kempen Pande Made Desy Ratnasari Poa, Patricia Novica Dua Pramesti, Ni Komang Ayu Dyah Pratiwi, Ni Kadek Saskya Putu Dian Marani Kurnianta Ratnasari, Pande Made Desy Wati, Ni Ketut Sindia