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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Kimia (Journal of Chemistry) JURNAL KIMIA SAINS DAN APLIKASI Jurnal Sains Materi Indonesia KOVALEN: Jurnal Riset Kimia Indonesia Chimica Acta Alotrop Jurnal Pendidikan dan Ilmu Kimia Dinamisia: Jurnal Pengabdian Kepada Masyarakat Jambura Journal of Chemistry RANDANG TANA - Jurnal Pengabdian Masyarakat Jurnal Farmamedika (Pharmamedica Journal) Jurnal Ilmu Kesehatan Jurnal Inovasi Teknik Kimia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Prosiding SIMKESNAS Jurnal Sains dan Kesehatan Jurnal Penelitian dan Pengabdian Masyarakat
Gusti Ayu Dewi Lestari
Program Studi S1 Farmasi, Sekolah Tinggi Farmasi Mahaganesha, Denpasar, Bali, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Biosynthesis of Gold Nanoparticles Mediated by Andaliman Fruit Water Extract and Its Application as Antioxidants Gusti Ayu Dewi Lestari; Kadek Duwi Cahyadi
Jurnal Kimia Sains dan Aplikasi Vol 25, No 2 (2022): Volume 25 Issue 2 Year 2022
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (729.738 KB) | DOI: 10.14710/jksa.25.2.56-62

Abstract

Plant extract-mediated green synthesis of gold nanoparticles (AuNPs) is currently gaining significant interest in the field of nanotechnology. In this study, AuNPs were synthesized using an aqueous extract of Andaliman fruit (Zanthoxylum acanthopodium DC.). The formation of AuNPs was confirmed by observing the color change of the solution from clear to cherry red. The reaction parameters, namely the extract concentration and the ratio of the mixture of the extract with HAuCl4 solution, were optimized for the AuNPs biosynthesis. The gold nanoparticles were characterized using a UV-Vis spectrophotometer, SEM-EDS, and particle size analyzer. The characterization suggested that AuNPs had a maximum wavelength ranging of 540–559 nm, with spherical crystals morphology where the highest component was gold at 36.01% and the size below 100 nm on average. The antioxidant activity of the synthesized AuNPs was determined using the DPPH method. It showed that the highest free radical scavenging activity was 83%, given by 20 ppm AuNPs.
UJI KUALITATIF DAN KUANTITATIF TETRASIKLIN DALAM SIMULASI SAMPEL SECARA SPEKTROFOTOMETRI UV-VIS Ni Ketut Esati; Kadek Duwi Cahyadi; Gusti Ayu Dewi Lestari
Jurnal Farmamedika (Pharmamedika Journal) Vol 8 No 1 (2023): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v8i1.190

Abstract

Analisis kualitatif dengan pereaksi warna merupakan metode pendahuluan yang dapat dilakukan untuk menentukan keberadaan suatu zat. Perbedaan sensitivitas pada tiap pereaksi terhadap suatu zat dapat berbeda-beda. Uji kuantitatif tetrasiklin pada sampel menggunakan metode spektrofotometri UV-Vis memerlukan metode ekstraksi yang paling optimal sehingga memberikan hasil yang baik. Tujuan dari penelitian ini adalah untuk mencari batas deteksi suatu pereaksi warna terhadap tetrasiklin, dan analisis kuantitatif yang diawali dengan optimasi metode ekstraksi tetrasiklin dari sampel. Selain itu juga dilakukan validasi metode analisis tetrasiklin dengan spektrofotometri UV-Vis yang meliputi parameter linearitas, LOD dan LOQ, presisi, serta akurasi. Pada penelitian ini telah dipelajari respon dari 2 pereaksi warna terhadap larutan baku tetrasiklin. Pereaksi formalin 37% dan asam sulfat 98% dapat mendeteksi larutan tetrasiklin sampai konsentrasi terkecil yaitu 500 ppm. Pada penelitian ini juga dilakukan perbandingan metode ekstraksi Buffer McIlvaine pH 4-NaEDTA dan Buffer McIlvaine pH 4-metanol. Diperoleh bahwa metode ekstraksi Buffer McIlvaine pH 4-metanol yang efisien digunakan untuk mengekstraksi tetrasiklin dalam sampel daging ayam, yang hasil ekstraksinya diukur dengan spektrofotometer UV-Vis. Metode pengukuran tetrasiklin menggunakan metode spektrofotometri UV-Vis telah divalidasi, sehingga diperoleh nilai: LOD 0,9982 ppm; LOQ 3,3275 ppm; %RSD 1,01% dan 1,36%; serta nilai recovery sebesar 100,66 %.
ANALISIS MUTU MINYAK KELAPA (VCO) YANG DIPEROLEH DARI BUAH KELAPA (Cocos nucifera L.) Gusti Ayu Dewi Lestari; Kadek Duwi Cahyadi
PROSIDING SIMPOSIUM KESEHATAN NASIONAL Vol. 2 No. 1 (2023): Simposium Kesehatan Nasional
Publisher : LPPM STIKES BULELENG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.129 KB)

Abstract

Minyak Kelapa merupakan minyak yang diperoleh dari daging buah kelapa tua segar dan diproses dengan diperas dengan atau tanpa pemanasan tidak lebih dan 60°C dan aman di konsumsi. Penelitian ini bertujuan untuk mengetahui mutu dari minyak kelapa sesuai SNI 7381-2008. Pada penelitian ini dilakukan uji mutu yaitu uji kadar air, uji bilangan iod, uji kadar asam lemak, uji bilangan peroksida. Hasil uji mutu pada minyak kelapa (VCO) ini diperoleh kadar air 0,19%, bilangan iod 6,38 gram iod/100 gram, asam lemak bebas 0,18%, bilangan peroksida 0,66 mgrek/g dimana hasil tersebut telah memenuhi standar SNI 7381-2008
Sintesis Nanopartikel Perak (NPAg) Menggunakan Ekstrak Air Buah Andaliman (Zanthoxylum acanthopodium DC.) dan Aplikasinya pada Fotodegradasi Indigosol Blue Gusti Ayu Dewi Lestari; Iryanti Eka Suprihatin; James Sibarani
Jurnal Kimia Sains dan Aplikasi Vol 22, No 5 (2019): Volume 22 Issue 5 Year 2019
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2495.226 KB) | DOI: 10.14710/jksa.22.5.200-205

Abstract

Nanopartikel perak (NPAg) adalah partikel logam perak yang memiliki ukuran kurang dari 100 nm. NPAg memiliki beberapa keunggulan, salah satunya sebagai katalis dalam proses fotodegradasi. NPAg diperoleh dengan mereduksi AgNO3menggunakan ekstrak air buah andaliman (Zanthoxylum acanthopodium DC.). Metode sintesis ini sangat efektif karena cepat, tidak beracun dan teknologi yang ramah lingkungan. Penelitian ini bertujuan untuk mensintesis NPAg optimum dan aplikasinya dalam proses fotodegradasi Indigosol Blue berupa volume, waktu iradiasi, dan pH optimum. Sintesis NPAg diamati menggunakan spektrofotometer UV-VIS sedangkan ukurannya diamati menggunakan PSA (Particle Size Analyzer). Hasil penelitian menunjukkan sintesis NPAg terbaik menggunakan AgNO3 1x10-3 M pada suhu 60°C dengan ukuran NPAg 9,04 nm. NPAg yang terbentuk stabil selama ± 35 hari. Kondisi optimum fotodegradasi adalah menggunakan 2 mL NPAg selama 4 jam irradiasi pada pH 3. Dari hasil penelitian ini dapat disimpulkan bahwa NPAg mampu menurunkan konsentrasi zat warna Indigosol Blue sampai dengan 94,75%.
Penyuluhan dan Pembuatan Produk Lilin Aromaterapi Berbasis Minyak Jelantah Di Desa Sibang Kaja Gusti Ayu Dewi Lestari; Balqish Fathoum Medinna; Jessica Sanchez Anggraini
Randang Tana - Jurnal Pengabdian Masyarakat Vol 6 No 3 (2023): Randang Tana - Jurnal Pengabdian Masyarakat
Publisher : Unika Santu Paulus Ruteng

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36928/jrt.v6i3.1788

Abstract

Indonesia is a country with a very high level of consumption of cooking oil where the amount of used cooking oil waste, is also very high in Indonesia. In general, this waste is not utilized optimally resulting in environmental pollution. To overcome the problems associated with used cooking oil, efforts are made so that this waste does not pollute the environment. One of the uses of used cooking oil is making aromatherapy candles from used cooking oil. Aromatherapy candles are candles that are made by adding fragrances with various purposes and benefits that can be used as room fresheners and to calm down. Counseling and candle making training was attended by members of the youth posyandu in Sibang Kaja Village, Abiansemal District. Participants experienced an increase in knowledge after being given an explanation regarding the manufacture of aromatherapy candle products with an initial value of 77.2% and a final value of 91.2%. From these data it shows that the difference in the average knowledge value of the participants' pretest and posttest is 14%. The existence of this value difference indicates that there is a difference between knowledge among the community before counseling and making aromatherapy candles and after this activity is carried out.
KUALITAS KIMIA ESSENTIAL OIL DARI KULIT JERUK PURUT HASIL HYDRODISTILLATION KELOMPOK MASYARAKAT DI BADUNG BALI Gusti Ayu Dewi Lestari
Randang Tana - Jurnal Pengabdian Masyarakat Vol 7 No 2 (2024): Randang Tana - Jurnal Pengabdian Masyarakat
Publisher : Unika Santu Paulus Ruteng

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36928/jrt.v7i2.2231

Abstract

Kaffir lime (Citrus hystrix DC.) is an economical product and has high health value. Generally, kaffir lime peel is the part that contains a lot of essential oils, so it is used by community groups in Badung Regency, Bali, specifically in Dalung Village, to extract this essential oil. The aim of this activity is of course to chemically test the quality of the products that partners have produced which will then provide knowledge to partners about the importance of producing good quality so that the products produced are able to compete in society. A GC-MC (Gas Chromatography-Mass Spectroscopy) test was carried out on this essential oil to determine the content of the essential oil that has been produced by the partner, where the GC-MS results showed that the essential oil of kaffir lime skin produced by the partner was 81,90% citronella compounds. In this service activity, community understanding regarding essential oils was also carried out, where with this activity, community understanding increased as seen from the pre-test and post-test scores.
Analisis Mutu Minyak Zaitun Yang Diperoleh Dari Buah Zaitun (Olea eurofaea) Dan Aplikasinya Sebagai Antikolesterol Duwi Cahyadi, Kadek; Dewi Lestari, Gusti Ayu; Esati, Ni Ketut
Jambura Journal of Chemistry Vol 5, No 1 (2023): February
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jambchem.v5i1.16767

Abstract

Olive oil is oil obtained from olives (Olea europaea L.). Olive oil contains high in oleic acid so it can be used as an anticholesterol. This study aims to determine the quality of olive oil according to SNI 01-4474-1998 and its anticholesterol activity by UV-Vis spectrophotometry. In this research, olive oil quality test was conducted, namely water content test using the thermogravimetric method, fatty acid content test using an alkalimetric titration method based on an acid-base reaction, saponification test using the acidimetric method, and iodine number test using the iodometric titration method. The method of testing the anticholesterol activity of olive oil was carried out in vitro using Lieberman-Burchard reagent. The results of the quality test on olive oil obtained water content of 0.03%, free fatty acids 1.73%, saponification number 190.90 mgKOH/g, iodine number 91.25g iodine/100g, where these results have met the SNI 01-4474-1998 standard. The results of the anticholesterol test showed a decrease in free cholesterol levels by 39.76%. Olive oil shows anticholesterol activity due to the presence of oleic acid or MUFA (Mono Unsaturated Fatty Acids)
Synthesis of Silver Nanoparticles Using Marigold (Tagetes erecta) Flower Extract for Photodegradation of Methylene Blue Dye Suprihatin, Iryanti Eka; Antariksa, Najwa Kusuma Putri; Kunti Sri Panca Dewi, I Gusti Ayu; Dewi Lestari, Gusti Ayu; Intan Wahyuni, Pande Made
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 16, No 2: December 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70561/ica.v16i2.28376

Abstract

The utilization of methylene blue dye in the textile industry can have a significant environmental impact due to its high toxicity. To address this issue, a study was conducted on the photodegradation of methylene blue dye using silver nanoparticles (AgNP) synthesized with marigold (Tagetes erecta) flower extract as a bioreducer. This article reports on the synthesis of AgNP and its application in the photodegradation of methylene blue dye. The synthesis of AgNP involved the reduction of AgNO3 with marigold flower extract. Different ratios of marigold flower extract to AgNO3 solution (0.01 M) were used: 1:9, 2:8, 3:7, 4:6, and 5:5. The formation of AgNP was monitored at various time intervals using UV-Vis spectroscopy. The best AgNP sample was measured using a Particle Size Analyzer (PSA). The research results indicated that the optimal conditions were achieved at a marigold extract to AgNO3 ratio of 2:8, with the UV-Vis spectrum showing a peak at a wavelength of 411 nm. The optimum conditions for photodegradation were as follows: AgNP volume of 15 mL, irradiation for 30 minutes, and pH 4. Under these conditions, photodegradation of methylene blue dye achieved a reduction of up to 72.46% from the initial concentration of 100 ppm.
Association Analysis of Complications, Number of Drugs, and Medication Adherence in End-Stage Renal Disease Patients Undergoing Hemodialysis Ratnasari, Pande Made Desy; Yuliawati, Agustina Nila; Lestari, Gusti Ayu Dewi; Andaresta, Ni Luh Putu Silvia
Jurnal Ilmu Kesehatan Vol 11 No 2 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i2.3809

Abstract

Hemodialysis (HD) in its implementation is reported to cause complications. Complications may cause the patients to receive >3 types of drugs and decrease their medication adherence. This study aimed to analyze the association between the number of complications and the number of drugs, and the association between the number of drugs with medication adherence in End-Stage Renal Disease (ESRD) patients. This research was conducted at the private hospital Denpasar in March-May 2021 with a cross-sectional design involving 93 respondents. The purposive sampling technique was used according to inclusion criteria (ESRD patients with complications, undergoing HD at least twice a week, signing informed consent) and exclusion criteria (having poor or unstable health, unable to communicate well). The research instrument used was a questionnaire (ESRD-AQ). The Mann-Whitney test and Kendall tau-b test were used to analyze the association in this study. The results showed that the majority of patients were <65 years old (83.9%), male (66.7%), 35.5% high school education, still working (51.6%), and long of diagnosed with ESRD <5 years (77%). The average patient had ≥2 complications (81.72%) and 80.64% received 1-6 types of drugs with high levels of medication adherence (67.74%). There was an association between the number of complications and the number of drugs (p=0.026) and the association between the number of drugs and medication adherence (p=0.023) with a weak correlation (r=-0,227). This indicates that complications can affect the number of drugs consumed and indirectly also affect the medication adherence of ESRD patients.
Uji Aktivitas Antioksidan Ekstrak Etanol Daun Rosemary (Rosemarinus officinalis L.) dengan Metode DPPH dan FRAP serta Pengaplikasiannya sebagai Zat Aktif dalam Losion: Antioxidant Activity Test of Rosemary Leaves (Rosemarinus officinalis L.) Ethanolic Extract with DPPH and FRAP Method and Its Application as an Active Substance in Lotion Ni Ketut Esati; Elisabeth Oriana Jawa La; Gusti Ayu Dewi Lestari
Jurnal Sains dan Kesehatan Vol. 4 No. 4 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i4.1129

Abstract

Salah satu tanaman yang mempunyai nilai ekonomis tinggi yaitu tanaman rosemary (Rosemarinus officinalis L.).  Tanaman ini mempunyai aroma dan rasa yang khas dan banyak mengandung senyawa yang dapat dimanfaatkan sebagai antioksidan, antijamur, antivirus, antibakteri, antitumor, antitrombotik, dan antidepresan. Pemanfaatan tanaman rosemary terutama ekstrak daunnya dapat dilakukan dengan terlebih dahulu melakukan pengujian terhadap ekstrak tersebut, sehingga tujuan dari penelitian ini adalah melakukan pengujian kandungan metabolit sekunder, uji aktivitas antioksidan dengan metode DPPH dan FRAP, serta mengaplikasikannya sebagai zat aktif dalam produk lotion. Dari hasil penelitian ini didapatkan rendemen ekstrak etanol daun rosemary sebanyak 16,87%. Hasil pengujian ekstrak tersebut mengandung senyawa metabolit sekunder diantaranya alkaloid, flavonoid, tannin, dan triterpenoid, namun memberikan hasil yang negatif terhadap saponin. Uji aktivitas antioksidan dengan metode DPPH dan FRAP ekstrak menghasilkan nilai IC50 berturut-turut 10,68 ppm dan 51,84 ppm. Dengan demikian ekstrak etanol daun rosemary memiliki aktivitas antioksidan yang sangat kuat dengan pengujian metode DPPH dan aktivitas yang kuat dengan metode FRAP. Produk antioksidan sediaan topikal berupa lotion dengan zat aktif dari ekstrak etanol daun rosemary menghasilkan uji organoleptis yang baik.
Co-Authors Abiansyah, Faisal Oktaviani Pratama Agustina Nila Yuliawati Andaresta, Ni Luh Putu Silvia Antariksa, Najwa Kusuma Putri B. Ankamwar Balqish Fathoum Medinna Dewi, Ni Putu Nita Lusiana Duwi Cahyadi, Kadek Elisabeth Oriana Jawa La Esati, Ni Ketut Gusti Ayu Putu Prima Purnamasari I Putu Eka Budiarta Intan Wahyuni, Pande Made Iryanti Eka Suprihatin Iryanti Eka Suprihatin James Sibarani James Sibarani Jessica Sanchez Anggraini K. D. Cahyadi Kadek Duwi Cahyadi Kadek Duwi Cahyadi Kadek Duwi Cahyadi Kadek Duwi Cahyadi Kunti Sri Panca Dewi, I Gusti Ayu Kusuma, Luh Adi Ngurah Wijaya Putra Ni Ketut Esati Ni Ketut Esati Ni Made Widayanti Ni Made Widayanti Ni Wayan Nieskajanti Kedeh Van Kempen Pande Made Desy Ratnasari Poa, Patricia Novica Dua Pramesti, Ni Komang Ayu Dyah Pratiwi, Ni Kadek Saskya Putu Dian Marani Kurnianta Ratnasari, Pande Made Desy Wati, Ni Ketut Sindia