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All Journal International Journal of Advances in Applied Sciences AL KAUNIYAH Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat AGRIVITA, Journal of Agricultural Science Jurnal Penelitian Pendidikan IPA (JPPIPA) BIOEDUSCIENCE Journal of Tropical Ethnobiology
Ratna Yuniati
Department Biology, Faculty Of Mathematics And Natural Sciences, Universitas Indonesia Depok, West Java, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Physics Public Health

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Utiliization of Natural Compound from Pegagan (Centella asiatica (L.) Urb.) and Their Potential Role in the Health Sector Ratna Lestyana Dewi; Ratna Yuniati; Yasman
Jurnal Penelitian Pendidikan IPA Vol 11 No 4 (2025): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i4.10558

Abstract

Centella asiatica, also known as Gotu Kola, is a medicinal plant widely used in traditional medicine. This abstract discusses its various health benefits supported by scientific research, including wound healing, cognitive enhancement, and anxiety reduction. It also explores its potential in treating skin conditions, venous insufficiency, and improving circulation. Further research is needed to fully understand its mechanisms of action and optimize its therapeutic applications. Centella asiatica (C. asiatica), commonly known as Gotu Kola, is a herbaceous plant extensively used in traditional Asian medicine for centuries. This review summarizes the scientifically validated health benefits of C. asiatica based on available research, primarily from Scopus-indexed publications. The plant's bioactive compounds, including triterpenoid saponins (asiaticoside, madecassoside, asiatic acid, and madecassic acid), contribute to its diverse pharmacological activities. C. asiatica exhibits significant wound healing properties by promoting collagen synthesis, angiogenesis, and fibroblast proliferation. Furthermore, studies suggest its potential in enhancing cognitive function, reducing anxiety, and improving memory. Its efficacy in treating skin conditions like eczema and psoriasis, as well as venous insufficiency and microcirculation, has also been reported. While promising, further research is needed to elucidate the precise mechanisms of action, determine optimal dosages, and explore potential synergistic effects with other therapeutic agents for various health conditions. This review aims to provide a comprehensive overview of the evidence-based health benefits of C. asiatica, highlighting its potential as a valuable natural remedy in modern medicine.
Co-Authors Adra Amalia Nur Ahlina Ajenk Ayunda Amara Rahmadina Ananda Putri Anisa Anggraeni Astari Dwiranti Deti Purwanti Fathia Ainusyifa Khayrani, Apriliana Cahya Lischer, Kenny Margaretta Elsa Damayanti Marina Silalahi Nadhifa Tazkia Ramadhani Nidaan Khafian Ovita Trianingsih Putrika, Afiatry Ratna Lestyana Dewi Retno Lestari Retno Lestari SAHLAN, MUHAMAD Sri Rahayu, Amy Yayuk Wahyu Ristiani Windri Handayani Wisnu Wardhana Wisnu Wardhana Yasman Yasman