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All Journal Jurnal Fisika Unand Jurnal Riset Kimia IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Jurnal Zarah Akta Kimia Indonesia Media Ilmu Kesehatan Molekul: Jurnal Ilmiah Kimia Current Research on Biosciences and Biotechnology Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Hydrogen: Jurnal Kependidikan Kimia JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal Katalisator Molekul: Jurnal Ilmiah Kimia
Suryati
Departemen Kimia, Fakultas Matematika Dan Ilmu Pengatahuan Alam, Universitas Andalas, Padang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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PROFIL FITOKIMIA DAN AKTIFITAS ANTIACETYLCHOLINESTERASE DARI DAUN TABAT BARITO (Ficus Deltoidea Jack) -, Suryatir; Nurdin, Hazli; -, Dachriyanus
Jurnal Riset Kimia Vol 2, No 2 (2009): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v2i2.157

Abstract

 ABSTRACT Phytochemical study and antiacetylcholinesterase assay by using bioautography method were carried out on polar fraction of tabat barito (Ficus deltoidea jack) leaves. The result of this studies showed that the leaves contained flavonoid, terpenoid, steroid and fenolic compounds. This extract gave positive result on antiacetylcholinesterase. Keywords: Antiacetylcholinesterase, Ficus deltoidea Jack   
AKTIVITAS ANTIBAKTERI SENYAWA METABOLIT SEKUNDER DARI FRAKSI ETIL ASETAT DAUN LENGKENG (Dimocarpus longan Lour.) DAN UJI AKTIVITAS Arifin, Bustanul; Suryati; Tetra, Olly Norita; Maghfirah, Sucy
Jurnal Zarah Vol 8 No 2 (2020): Jurnal Zarah
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/zarah.v8i2.2460

Abstract

Isolasi dan karakterisasi struktur senyawa metabolit sekunder dari fraksi etil asetat daun lengkeng (Dimocarpus longan Lour.) telah dilakukan dan dipelajari aktivitas antibakterinya. Isolasi dilakukan dengan teknik kromatografi kolom gravitasi menggunakan fasa diam silika gel dan fasa gerak n-heksana, etil asetat dan metanol dengan sistem elusi peningkatan kepolaran (SGP) dan isokratik. Pemurnian senyawa hasil isolasi dilakukan dengan cara triturasi. Senyawa murni hasil isolasi yang diperoleh berupa padatan putih dengan titik leleh 126-127°C dan menunjukkan uji positif triterpenoid dengan pereaksi Liebermann-Burchard. Karakterisasi struktur senyawa triterpenoid hasil isolasi menggunakan data spektrum UV menunjukkan bahwa triterpenoid hasil isolasi tidak memiliki ikatan rangkap berkonjugasi. Analisis data spektrum IR menunjukkan bahwa triterpenoid hasil isolasi memiliki pita serapan gugus OH (3326,46 cm-1 ), ikatan C–O (1270,80 cm-1 dan 1038,76 cm-1 ) dan geminal dimetil (1379,46 cm-1 ) yang merupakan ciri khas senyawa triterpenoid. Uji aktivitas antibakteri dilakukan dengan metode difusi, hasilnya menunjukkan senyawa triterpenoid memiliki daya hambat lemah dibanding dengan amoxicillin dalam menghambat pertumbuhan bakteri Staphylococcus aureus dan Escherichia coli.
HUBUNGAN USIA MENIKAH DENGAN KEJADIAN KANKER SERVIKS DI WILAYAH KABUPATEN BANTUL YOGYAKARTA Hidayah, Siti Nur; Kusumasari, Viantika; Suryati
MEDIA ILMU KESEHATAN Vol 9 No 3 (2020): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v9i3.603

Abstract

Background: Cervical cancer is a malignant tumor due to the growth of abnormal cells in the female reproductive system. The prevalence of cervical cancer is highest in DIY 4,86 per 1000 population. One of cause cervical cancer is infection of HPV virus that can be caused by age of marriage. Objetive: The purose of this study was to determine the relationship of the marriage age with the incidence of cervical cancer. Method: The method used in the research is case control study. Sampling technique is purposive sampling. This study used 76 samples, consisting of 38 case groups and 38 control groups. The data were analyzed by chi-squere test. Result: Most respondent at the case group first married at age < 20 years (57,9%) than at the control group the majority of the age of first marriage at age ≥20 years (78,9%). After testing with Chi-Squere analysis the result obtained (p=0,002; CI 1,875-14,177; OR=5,156) which means there is a significant relationship between age of marriage with cervical cancer in the region of Bantul Regency Yogyakarta. Conclution: Women married at < 20 years of age have a 5 times greater risk of cervical cancer than women married at age ≥ 20 years.
Uji Aktivitas Sitotoksik dan Antibakteri Ekstrak Daun Tumbuhan Rengas (Gluta renghas L) Sanusi Ibrahim; Suryati Suryati; Enda Desriansyah Aziz
Jurnal Riset Kimia Vol. 11 No. 1 (2020): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v11i1.345

Abstract

Generally, Gluta renghas L. is known because of its very toxic latex which can cause hard irritations to skin. Although, rengas latex has efficacy as an antibacterial agent. Related to previous research, it has been reported that there are urisol, rengol, glutarengol, laccol, and thitsiol in rengas latex. The woody trunk was reported to contain flavonoid, benzenoid, lipid, and steroid compounds. The leaves, were reported shows that the leaves of G. renghas contain an anticholinesterase substance and can be reduced the rate of hydrolysis of acetylcholine. Extraction of rengas leaves has been carried out. It has been shown phenols, steroids, and coumarins compounds in methanol extract, flavonoids, phenols, saponins and alkaloids compounds in ethyl acetate extract, steroids and alkaloids compounds in hexane extract. In the present, cytotoxicity and antibacterial activity have been tested. The results show that the great cytotoxicity activity by ethyl acetate extracts which have an LC50 value is 123,718 µg/mL (R2 0.9822), while the great antibacterial activity shown by methanol extract 1,000 µg/mL with a diameter of inhibition zone 19.02 mm (S. aureus) and 16.06 mm (E. coli). 
Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells Suryati Suryati; Enda Desriansyah Aziz; Mai Efdi; Fatma Sri Wahyuni; Dira Hefni
Jurnal Riset Kimia Vol. 12 No. 1 (2021): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v12i1.364

Abstract

Lantana camara Linn is a family of Verbenaceae which grows wild and is widespread in various both tropical and sub-tropical countries. Isolation essential oil of the L. camara leaves extracted by hydrodistillation and were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). The results of GC-MS analysis show isocaryophyllene (14.39%), ρ-cymene (8.17 %), β-cubebene (7.8 %), α-pinene (7.64 %), and β-elemene (5.51 %) as the main compound. The cytotoxic activity of the isolated essential oil was highly toxic both to Artemia salina shrimp larvae (LC50 15.92 µg/mL) and to breast cancer cells T-47D (IC50 10.67 µM).
Penentuan Profil Metabolit Sekunder, Aktivitas Antioksidan dan Antibakteri dari Ekstrak Biji Kurma (Phoenix dactylifera L.) Bebas Lipid Afrizal Afrizal; Aditya Perdana; Suryati Suryati
Jurnal Riset Kimia Vol. 13 No. 1 (2022): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v13i1.423

Abstract

Dates are one of the plants that grow in the Middle East, one of them is the Golden Valley variety. Dates are usually consumed directly and can also be processed into date juice drinks. Dates refined process would produce waste in the form of date seeds are discarded and not processed into other products. This study used lipid-free Golden valley date seed extract to determine the secondary metabolite profile by using LC-MS/MS method, determining phenolic content using the Folin-Ciocalteau method, determining total flavonoids using the aluminium chloride method, determining antioxidant activity by DPPH method, and determination of antibacterial activity by the disc diffusion method. The results showed that the compounds identified from the lipid-free date seed extract were catechin-(4α→8)-catechin, bis((1S,2R,5S)-5-isopropyl-2,3-dimethylcyclo-hexyl)-2,6-dimethylpyridine-3,5-dicarboxylate, 3,5,6-trihydroxy-4',7-dimethoxyflavone, ethyl-2-amino-3-oxobutanoate, and bis(2-isopropyl-5-methylcyclohexyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridine dicarboxylate. Lipid-free date seed extract contains total phenolic and flavonoid totals of 4364.704 mgGAE/100 grams of dried extract and 17200 mgQE/100 grams of dried extract. Its antioxidant activity is very strong in counteracting DPPH free radicals indicated by IC50 value of 10.1951 mg/L. Antibacterial activity shows strong inhibition of Staphylococcus aureus bacteria compared to inhibition of Escherichia coli bacteria that are categorized as weak.
A Triterpenoid Compound From The Leaves of Lantana camaraLinn. Kartika MZ Kartika; Suryati Suryati; Mai Efdi
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 3, No 1 (2018): February 2018
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v3.i1.18

Abstract

A triterpenoid compound has been isolated from the ethyl acetate fraction of Lantana camaraLinn leaves. The isolation was performed by chromatography of gravitation column with a gradient elution system using hexane, ethyl acetate and methanol. Purification by recrystallization produces a white solid (20 mg) with a melting point of 288-289 °C. The results of elucidation of UV, IR, 1H-NMR, 13C-NMR, HMBC, HSQC, DEPT and COSY spectral data, it is known that the isolated triterpenoid compound is 22β-angeloyloxy-9-hydroxy-3-oxo-olean-12- en-28-oicacid with molecular formula C35H52O6. Keywords—Lantana camaraLinn, Chromatography of gravitation column, Triterpenoid, C35H52O6
Antibacterial activity of secondary metabolites isolated from Ficus aurata (Miq.) Fruits Nurhamidah Nurhamidah; M Lutfi Firdaus; Suryati Suryati; Yosie Andriani
Current Research on Bioscences and Biotechnology Vol. 3 No. 1 (2021)
Publisher : Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/crbb.2021.3.1/A2F9IMF6

Abstract

This research aimed to isolate chemical constituents from ethyl acetate and n-hexane fractions of Ficus aurata (Miq.) fruits and investigated their antibacterial activity. Chemical constituents were separated using vacuum liquid chromatography, gravity column chromatography, and thin-layer chromatography. The structures of the isolated compounds 3,4-dihydroxybenzoic acid (1) and β-sitosterol (2) were elucidated using various spectroscopic methods, including UV, IR, and NMR (1H-NMR, 13C-NMR, and DEPT). While, antibacterial activity was done using resazurin microtiter assay. These 2 compounds were first time reported from F. aurata fruit. In addition, analysis of the bioassay showed that compound 1 had a notable antibacterial activity against Gram negative (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATTC 27853), and a gram-positive bacterium (Staphylococcus aureus ATCC 23235) with the minimum inhibitory concentration (MIC) value of 0.1563 µg/ml, and it indicated the same MIC as cefadroxil (positive control). Compound 2 has weak antibacterial activity compared to cefadroxil (positive control). The results found that F. aurata (Miq.) fruits metabolites have antibacterial activity and show potency as antibacterial agents. Different kinds of bacteria and assay could be needed to investigate and support its antibacterial activity in the future.
A Cytotoxic Compound from n-Hexane Fraction of Lantana camara Linn Leaves Suryati Suryati; Yuni Malasari; Mai Efdi; Elida Mardiah
Molekul Vol 14, No 1 (2019)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.155 KB) | DOI: 10.20884/1.jm.2019.14.1.477

Abstract

In this study, one triterpenoid compound from n-hexane fraction of Lantana camaraLinn leaves has cytotoxic activity was isolated. Isolation was carried out using gravity chromatographycolumnand purification by recrystallization method. Isolated compound was obtained white solid with melting point 252-253oC. The structure of isolated compound was elucidated using spectroscopic analysis Ultraviolet (UV), Infrared (IR), 1H-Nuclear Magnetic Resonance (1H-NMR), 13C-Nuclear Magnetic Resonance (13C-NMR) Heteronuclear Multiple Bond Connectivity (HMBC),  Heteronuclear Multiple Quantum Correlation (HMQC), Distortionless Enhancement Polarization Transfer (DEPT) and comparative literature data, identified as Lantadene A (22β-angeloyloxy-3-oxoolean-12-en-28-oic-acid) with molecule formula C35H52O5. The Lantadene A compound was evaluated for cytotoxic activity against shrimp larvae Artemia SalinaLeach using Brine Shrimp Lethality Test(BSLT) method, showed strong cytotoxic activity with an LC50value of 48.97 µg/mL.
POTENSI MINYAK ATSIRI DARI DAUN TUMBUHAN SAMBUANG (Etlingera elatior) SEBAGAI SENYAWA ANTIBAKTERI DAN ANTIOKSIDAN M. Fadly; Suryati Suryati; Farid Al-Huzaini; Nadila Arrahim
JURNAL KIMIA SAINTEK DAN PENDIDIKAN Vol 5 No 2 (2021): JURNAL KIMIA SAINTEK DAN PENDIDIKAN
Publisher : Program Studi Kimia - Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (942.742 KB)

Abstract

Sambuang (Etlingera elatior) is a member of the Zingiberaceae family which is widely distributed in Indonesia. Traditionally, sambuang is used for cooking spices and to cure various diseases, namely diseases of the ears, stomach, skin wounds, and stomach pain due to poisoning. In this study, essential oils were isolated from sambuang leaves and antibacterial and antioxidant activities were also determined. Isolation of essential oil was carried out by steam distillation and the chemical content of the isolated essential oil was analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). It is known to contain 98 chemical compounds, with the main ingredients being a-Pinene (19.39%), Gadoleyl Alcohol (7.37), Myristoleyl Alcohol (7.16%), Palmitoleyl Alcohol (5.87%), Sabinene (5 ,48%). The results of the antibacterial activity of essential oils using the disc diffusion method showed strong activity against Escherichia coli, Salmonella typhi (50% concentration) and Staphylococcus aureus (70% concentration) with inhibition zones of 13.6 mm, 12 mm, respectively. and 11 mm. The results of the antioxidant activity test using the DPPH method (1,1-diphenyl-2-picrylhydrazyl) showed that the essential oil of sambuang leaf essential oil was not effective as an antioxidant because it was very weak with an IC50 value of 6939.18 g/mL.
Co-Authors Aditya Perdana Adlis Santoni Afrizal Afrizal Aisya, Nurul Asri Amelia Bustanul Arifin Bustanul Arifin Bustanul Arifin Bustanul Arifin Dachriyanus Deswati Deswati Elida Mardiah Emriadi - Enda Desriansyah Aziz Enda Desriansyah Aziz Farid Al-Huzaini Fatma Sri Wahyuni Frisky, Sintia Gustia Elizar Hilda Sartika Indah Putri Lestari Kartika MZ Kartika MZ Kartika Kusumasari, Viantika Leidina Zein M Lutfi Firdaus M. Fadly Maghfirah, Sucy Mai Efdi Matlal Fajri Alif Miftahul Melsya Salsabilla Mudinillah, Adam Nadila Arrahim Norman Ferdinal Novesar Jamarun Nurdin, Hazli Nurhamidah Nurhamidah Olly Norita Tetra Rahmi Vika Ulia Rini Ramadani Safni Safni Salim, Emil Sanaq Elfira Putri Sanusi Ibrahim Sari Wahyuni Shafinna Hana Fadhia Silfani Mairanti Siti Aisyah Siti Nur Hidayah, Siti Nur Syukri Arief Thaharah Alifa Aziz Yenuuar Vira Anggita Gusniardi Wini Sukrila Yayan Rabbani Kurniawan Yeni Stiadi Yetria Rilda Yosie Andriani Yulizar Yusuf Yuni Malasari Zilfa Zilfa