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All Journal Journal of Nutrition College Althea Medical Journal Damianus Journal of Medicine Neurona
Vetinly Vetinly
FKIK Universitas Katolik Indonesia Atma Jaya
Environmental Science Health Professions Medicine & Pharmacology Neuroscience Public Health

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Journal : althea medical journal

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Body Mass Index, a Body Shape Index, and Waist-to-Height Ratio in Predicting Elevated Blood Pressure Bryan Junius Winata; Veronika Maria Sidharta; Linawati Hananta; Vetinly Vetinly; Nawanto Agung Prastowo
Althea Medical Journal Vol 9, No 1 (2022)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v9n1.2291

Abstract

Background: One of the complications of obesity is an elevation in blood pressure  which can increase the risk of hypertension. This study aimed to explore body mass index (BMI), a body shape index (ABSI), and waist-to-height ratio (WHtR) in predicting elevated blood pressure (BP).Methods: This study was conducted in a cross-sectional design on 215 medical students from October 2019 to September 2020. Respondents measured their own weight, height, waist circumference and BP. Receiver operating characteristics (ROC) curve were analyzed using IBM SPSS v.23. Results: Of the 215 medical students who participated in this study, only 102 met the inclusion criteria. The majority of the students were female (n=71, 69.6%) with a mean age of 19.37 years, and normal blood pressure (n=90, 88.2%). Area under the ROC curve (AUC) of WHtR and ABSI were 0.774 (p-value= 0.002) and 0.766 (p-value= 0.003) respectively, which were still acceptable. However, the AUC of BMI (p-value=0.589) was 0.11, which was considered poor.Conclusion: The indicators of obesity can be used as a screening value for increased blood pressure in adults, with BMI being the weakest indicator compared to ABSI and WHtR. Further research is needed to examine ABSI and WHtR indicators as predictor of increased blood pressure in adults.
Dietary Intake, Nutritional Status, and Quality of Life in Patients with Thalassemia Major Steven Yulius Usman; Salvabilla Azheema Rahmat; Vetinly Vetinly; Felicia Kurniawan
Althea Medical Journal Vol 9, No 2 (2022)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v9n2.2301

Abstract

Background: Impaired growth and inadequacy of dietary intake in thalassemia patients may affect the quality of life. This study aimed to determine and examine the relationship between dietary intake, nutritional status, and quality of life in in patients with thalassemia major.Methods: This study was a cross-sectional descriptive study conducted from February to October 2020. Twelve respondents who were registered at the Yayasan Thalassemia Indonesia and the blood transfusion unit at Fatmawati Hospital participated. This study conducted a physical examination and distributed food record questionnaires and WHOQOL-BREF. Data analysis was performed using Nutrisurvey 2007 and Fisher’s exact test.Results: The majority of the respondent were male (58.3%), categorized in the age group 5–18 years (58.3%), had normal nutritional status (50%) and quality of life. Interestingly, the respondents had an excess intake of protein and fats, while the intake of energy and carbohydrates was normal. Respondents had less intakes of all micronutrients. Conclusion: The majority of respondents have normal nutritional status and quality of life but have a low intake of micronutrients. Both patients and parents need to be further educated on dietary intake to meet their nutritional needs
Effects of Aloe Vera Extract on Basal Cell Thickness and Lymphocyte Infiltration at the Gastroesophageal Junction in a Rat Model of Gastroesophageal Reflux Disease Shella Violita; Tena Djuartina; Vetinly Vetinly; Iskandar Rahardjo Budianto
Althea Medical Journal Vol 13, No 1 (2026)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v13n1.4208

Abstract

Background: Gastroesophageal reflux disease (GERD) is a chronic gastrointestinal  disorder with increasing global prevalence. Aloe vera contains bioactive compounds with potential anti-inflammatory properties. This study aimed to evaluate the anti-inflammatory effects of Aloe vera extract in a Sprague-Dawley rat model of GERD.Methods: This experimental study included 32 male Sprague-Dawley rats randomly divided into eight groups: normal (N), negative control (NC), two positive controls receiving pantoprazole for 7 or 14 days (PCI and PCII), and four treatment groups receiving Aloe vera extract at doses of 250 or 500 mg/kg body weight for 7 or 14 days (DI–DIV). After treatment, the rats were euthanized and gastroesophageal junction (GEJ) tissues were collected for histopathological analysis. Basal cell thickness and lymphocyte infiltration were assessed. Data were analyzed using one-way ANOVA followed by post hoc testing.Results: Administration of Aloe vera extract at doses of 250 and 500 mg/kg body weight significantly reduced basal cell thickness compared with the untreated GERD group (p<0.05). However, no significant reduction in lymphocyte infiltration  was observed (p>0.05).Conclusions: Aloe vera extract exhibits anti-inflammatory effects in GERD-induced rats by reducing basal cell thickness at the GEJ. These findings suggest its potential as a complementary therapeutic approach for GERD, although further studies are needed to evaluate long-term efficacy and safety.
Co-Authors Bryan Junius Winata Bryany Titi Santi Felicia Kurniawan Francisca Tjhay Iskandar Rahardjo Budianto Jeremy Jeremy Katheryn Etania Linawati Hananta, Linawati Linda Suryakusuma Luse Luse Lydia Esterlita Halim Maria Dara Novi Handayani, Maria Dara Novi Michael Nathaniel Budiarso Myra Antonia Nawanto Agung Prastowo Nelly Tina Widjaja Rensa, Rensa Salvabilla Azheema Rahmat Sarah Stephanie Br Ginting Shella Violita Steven Yulius Usman Tena Djuartina Veronika Maria Sidharta Yunisa Astiarani