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All Journal MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM Majalah Kedokteran Gigi Indonesia Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry
Hardita, Ardhianing
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Gigi tiruan lengkap kerangka logam sebagai alternatif perawatan pasien dengan refleks muntah Ardhianing Hardita; Heriyanti Amalia Kusuma; Titik Ismiyati; Erwan Sugiatno
MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM Vol 4, No 1 (2018)
Publisher : Fakultas Kedokteran Gigi, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mkgk.61408

Abstract

Refleks muntah merupakan mekanisme pertahanan tubuh yang normal untuk mencegah benda asing masuk ke dalam trakea, faring, atau laring. Ada beberapa tingkatan refleks muntah pada pasien yaitu dari ringan hingga berat. Pasien dengan refleks muntah ringan jika diberi stimulus dapat merasa mual namun dapat mengkontrol respon tersebut. Pasien yang memiliki refleks muntah lebih berat menunjukkan respon yang berlebihan ketika diberi stimulus fisik atau psikologis, pada kategori ini pasien mungkin tidak dapat menerima Tindakan pencetakan, prosedur operatif, atau insersi gigi tiruan. Permukaan basis gigi tiruan akrilik yang halus jika dilapisi oleh saliva mengakibatkan sensasi licin sehingga timbul refleks muntah dan mual pada pasien. Basis gigi tiruan lengkap yang dibuat dari bahan kerangka logam memiliki kekasaran pada permukaan palatal seperti rugae palatina dan lebih tipis sehingga lebih nyaman digunakan oleh pasien. Penggunaan kerangka logam sebagai basis gigi tiruan lengkap dapat menjadi salah satu alternatif untuk mengatasi refleks muntah pasien. Tujuan laporan kasus ini yaitu mengkaji kemampuan gigi tiruan lengkap kerangka logam untuk mengurangi refleks muntah pada pasien. Kasus: Pasien laki-laki, 58 tahun datang dengan keluhan kesulitan menggunakan gigi tiruan yang lama karena refleks muntah yang dialami pasien. Pemeriksaan intraoral menunjukkan daerah tidak bergigi pada seluruh rahang atas dan bawah pasien. Tata laksana kasus: Anamnesa, pemeriksaan klinis, dan rehabilitasi protesa gigi tiruan lengkap kerangka logam pada rahang atas dan bawah. Kesimpulan: Gigi tiruan lengkap kerangka logam dapat mengurangi refleks muntah pada pasien.
Effect of addition titanium dioxide nanoparticles as acrylic resin denture base filler on cytotoxicity Ardhianing Hardita; Titik Ismiyati; Endang Wahyuningtyas
Majalah Kedokteran Gigi Indonesia Vol 5, No 2 (2019): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.38438

Abstract

Denture base material should have a good level of biocompatibility. Acrylic resin is frequently used as a denture base material, however it has a disadvantage of producing residual monomer. Residual monomer is known to have a cytotoxicity effect. Titanium dioxide (TiO2) nanoparticles are used as fillers due to their biocompatibility and ability to enhance the mechanical properties of acrylic resin. The addition of the material to acrylic resin could affect the amount of residual monomer. The aim of this study was to examine the effect of the addition of TiO2 nanoparticles as acrylic resin denture base filler on the cytotoxicity in fibroblast cells. The samples consisted of 24 heat cured acrylic resins in disc shape (5 mm in diameter and 2 mm in thickness), divided into 4 groups (n = 6): three groups given treatment with0.5%, 1%, 2% TiO2, respectively and one control group. Cell viability was measured with MTT assay. The results were tested with one way ANOVA with 95% confidence level followed by LSD post hoc test. The results showed that the highest percentage of cell viability was found in the treatment group of 0.5% TiO2 with value of 91.83 ± 1.75%, while the lowest value was seen in the treatment group of 2% TiO2 with value of 79.38 ± 3.34%. Significant differences were shown between the treatment groups of 0.5% and 2% TiO2, as well as between the control and treatment group with 2% TiO2. The conclusions of this research are the addition of TiO2 nanoparticles as acrylic resin denture base filler has an effect on cytotoxicity; the addition of 0.5% TiO2 nanoparticles filler results in lower cytotoxicity on fibroblast cells compared to the addition of 1% and 2% TiO2.  
Analisis kekuatan tarik denture adhesive ekstrak daun tembakau sediaan krim terhadap resin akrilik heat cured: studi eksperimental Parnaadji, R Rahardyan; Hardita, Ardhianing; Putri, Althea Berlian; Kristiana, Dewi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 37, No 2 (2025): Agustus 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v37i2.61127

Abstract

Pendahuluan: Pasien lansia yang menggunakan gigi tiruan lengkap sering mengalami masalah pada saat adaptasi. Sediaan krim perekat gigi tiruan dapat meningkatkan kenyamanan namun memiliki kandungan zinc yang dapat menyebabkan pertumbuhan bakteri dalam rongga mulut, sehingga dicari bahan alternatif dari bahan alami. Tembakau (Nicotiana tabacum L.) diketahui mengandung senyawa bioaktif seperti alkaloid dan flavonoid yang berpotensi sebagai antibakteri, antimikroba sehingga tembakau (Nicotiana tabacum L.) dapat digunakan sebagai bahan adhesif gigi tiruan yang bersifat antimikroba. Penelitian ini bertujuan untuk menganalisis perbedaan kekuatan tarik denture adhesive ekstrak daun tembakau (Nicotiana tabacum L.) konsentrasi 10% dan 20% sediaan krim. Metode: Jenis penelitian ini adalah eksperimental laboratorik dengan rancangan penelitian yaitu post-test only control group design. Sampel penelitian sebanyak 27 sampel yang dibagi menjadi 3 kelompok, yaitu kelompok kontrol perekat gigi tiruan komersial, perekat gigi tiruan ekstrak daun tembakau 10%, dan perekat gigi tiruan ekstrak daun tembakau 20%, kemudian diberi perlakuan perendaman dalam saliva buatan selama 60 detik dan dilakukan uji kekuatan tarik dengan menggunakan Universal Testing Machine. Data yang diperoleh kemudian dianalisis dengan menggunakan uji normalitas Shapiro-Wilk, uji homogenitas Levene-test, uji Kruskal-Wallis dan uji Mann-Whitney Hasil: Perekat gigi tiruan ekstrak daun tembakau 10% memiliki nilai kekuatan tarik yang lebih tinggi jika dibandingkan dengan perekat gigi tiruan ekstrak daun tembakau 20%. Terdapat perbedaan yang signifikan (p<0,05) antara konsentrasi ekstrak daun tembakau 10% dan 20% dengan perekat gigi tiruan komersial Simpulan: Denture adhesive ekstrak daun tembakau (Nicotiana tabacum L.) 10% dan 20% memiliki kekuatan tarik yang sama baik, dengan nilai kekuatan tarik yang lebih tinggi pada ekstrak daun tembakau konsentrasi 10%.Tensile strength analysis of denture adhesive cream containing tobacco leaf extract on heat cured-acrylic resin: an experimental studyIntroduction: Elderly patients who use complete dentures often experience adaptation difficulties. Denture adhesive creams can improve comfort; however, many commercial products contain zinc, which may promote bacterial growth in the oral cavity. Therefore, natural alternative materials are being explored. Tobacco (Nicotiana tabacum L.) contains bioactive compounds such as alkaloids and flavonoids, which have antibacterial and antimicrobial potential. Thus, tobacco (Nicotiana tabacum L.) leaf extract can be utilized as an antimicrobial ingredient in denture adhesive formulations. This study aimed to analyze the differences in tensile strength between denture adhesive creams containing 10% and 20% concentrations of tobacco leaf extract. Methods: The research was carried out in a controlled experimental laboratory setting, utilizing a post-test-only design with a control group. A total of 27 samples were divided into three groups: a control group using commercial denture adhesive, a group using 10% tobacco leaf extract adhesive, and a group using 20% tobacco leaf extract adhesive. All samples were immersed in artificial saliva for 60 seconds before tensile strength testing using a Universal Testing Machine. Data were analyzed using the Shapiro-Wilk test for normality, the Levene-test homogeneity, followed by the Kruskal-Wallis and Mann-Whitney tests. Results: The 10% tobacco leaf extract denture adhesive exhibited a higher tensile strength value compared to the 20% extract formulation. A significant difference (p<0.05) was found between the 10% and 20% concentrations of tobacco leaf extract and the commercial denture adhesive. Conclusion: Denture adhesives containing 10% and 20% tobacco leaf extract (Nicotiana tabacum L.) both demonstrated good tensile strength, with 10% concentration showing superior tensile strength compared to the 20% formulation.
Role of cassava starch (Manihot esculenta Crantz) in reducing candida albicans adhesion on soft denture liners: an experimental study Adena, Afif Surya; Naini, Amiyatun; Soesetijo, FX Ady; Kristiana, Dewi; Parnaadji, Rahardyan; Hardita, Ardhianing
Padjadjaran Journal of Dentistry Vol 38, No 1 (2026): March 2026
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol38no1.68181

Abstract

Introduction: Soft denture liners can be an alternative solution for various removable denture problems, but they still have several limitations, such as promoting Candida albicans adhesion to dentures. Modifications incorporate cassava starch. The aim of this result is toanalyze the role of cassava starch in reducing Candida albicans adhesion on soft denture liners. Methods: This laboratory experimental study used twenty-seven disc-shaped heat-cured acrylic plates with a diameter of 10 mm and a thickness of 2 mm divided into three groups: acrylic plate without a coating (negative control group), acrylic plate coated with soft denture liners (positive control group), and acrylic plate coated with a soft denture liner containing cassava starch 15% (treatment group). The samples were soaked in artificial saliva for 1 hour, then contaminated with Candida albicans by placing them in a test tube containing a Candida albicans suspension, and incubated for 24 hours at 37°C. Samples were rinsed twice with PBS, then placed in a test tube containing 10 mL of Sabouraud's broth and vortexed for 30 seconds. The turbidity of the released Candida albicans was measured using a spectrophotometer. Absorbance data were analyzed using one-way ANOVA and post hoc LSD. Results: Turbidity testing using a spectrophotometer at 600 nm showed the average absorbance values were 0.013 for negative control group, 0.028 for the positive control group, and 0.019 treatment group. The results of the one-way ANOVA test showed a p-value of 0.004 (<0.05), indicating a significant difference between the groups. Further post hoc LSD tests showed that the positive control group had the highest absorbance value. At the same time, there was no significant difference between the negative control group and treatment group. Conclusion: Cassava starch inhibits Candida albicans adhesion to the soft denture liners.
Co-Authors Adena, Afif Surya Amiyatun Naini Dewi Kristiana Endang Wahyuningtyas Erwan Sugiatno FX Ady Soesetijo, FX Ady Heriyanti Amalia Kusuma Putri, Althea Berlian R Rahardyan Parnaadji, R Rahardyan R. Rahardyan Parnaadji Titik Ismiyati