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All Journal Medical Journal of Indonesia Jurnal Keperawatan (JKEP) Journal Of Health & Cardiovascular Nursing AACENDIKIA: Journal of Nursing
Pramita Iriana
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Electrical & Electronics Engineering Health Professions Medicine & Pharmacology Nursing Public Health

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The impact of β-hCG on placental angiogenesis in pre-eclampsia Subakir, Sri B.; Jauhari, Tri; Iriana, Pramita; Siagian, Minarma; Setiadji, Sutarmo
Medical Journal of Indonesia Vol 14, No 2 (2005): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (157.131 KB) | DOI: 10.13181/mji.v14i2.175

Abstract

Numerous factors, such as VEGF and intra-placental oxygenation, can influence placental angiogenic activity. Early in the normal gestation period, β-hCG enhance VEGF activity to induce angiogenesis. The aims of this study were to identify the correlation between β-hCG concentration in placental culture and placental angiogenic activity in pre-eclampsia. Ten placenta samples from women with pre-eclampsia and l0 from controls (normal pregnancy) were collected. All subjects agreed to participate in this study and signed an informed consent form. β-hCG concentration in supernatant of placental culture was measured by Microparticle Enzyme Immunoassay (MEIA) and placental angiogenic activity was measured by endothelial cell migration toward placental explant (score 0-4). The results showed that the median score of placental angiogenic activity in pre-eclampsia was significantly higher than in normal pregnancy (p<0.05). Concentration of β-ahCG in pre-eclampsia was significantly higher than in normal pregnancy (p<0.001). hCG concentration in placental culture was positively correlated to placental angiogenic activity both in pre-eclampsia (r=+0.50) and in normal pregnancy (r=+0.57). Althouglt the correlations were weak, β-hCG is considered one of the factors that influence placental angiogenic activity. (Med J Indones 2005; 14: 67-70)Keyvords: angiogenesis, β-hCG, plocenta, pre-eclampsia
Correlation of Knowledge and Family Support with Treatment Compliance of Tuberculosis Sufferers Sudrajat, Ace; Ayu Rahmadani, Ainina; Suratun; Iriana, Pramita; Lusiani, Dewi; Wartonah; Manurung, Santa; Sumbara
AACENDIKIA: Journal of Nursing Vol. 2 No. 2 (2023): AACENDIKIA: Journal of Nursing
Publisher : Althar Cendikia Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59183/aacendikiajon.v2i2.25

Abstract

Introduction: The Hypertension is a cardiovascular disease characterized by increased blood pressure. Pharmacological and non-pharmacological therapies are one of the factors that can control hypertension. Pharmacological therapy involves the use of drugs which is the basis of a person's compliance with treatment. Adherence in taking medication also has factors that can influence such as knowledge, family support, access to health services. Knowing the relationship between knowledge and family support with adherence to taking anti-hypertensive drugs in hypertensive patients at the Matraman District Health Center. Methods: This study is a quantitative study with an analytical descriptive design and uses a cross-sectional approach. The population in this study were all patients aged 40-73 years who sought treatment at the PTM Poly of the Matraman District Health Center. The sample taken was 96 respondents using purposive sampling technique. Data collection using a questionnaire and then analyzed using the Chi square test. Results: The results of research conducted on 96 respondents obtained on the characteristics of respondents most of the respondents were 52-73 years old, female gender, and secondary education level. The results of the chi square test showed that there was a relationship between knowledge and adherence to taking anti-hypertensive drugs (p-value 0.03) and family support with adherence to taking anti-hypertensive drugs (p-value 0.01). Conclusions: The There is a significant relationship between knowledge and family support with adherence to taking anti-hypertensive drugs in patients with hypertension at the Matraman District Health Center.
Blood Pressure Stability Within Normal Range in Hypertension Patients is Closely Related to Compliance with Medication and Low Salt Diet: Kestabilan Tekanan Darah pada Penderita Hipertensi Berhubungan dengan Kepatuhan Minum Obat dan Diet Rendah Garam Ace Sudrajat; Wulan D.C, Tsabita; Yardes, Nelly; Manurung, Santa; Lusiani, Dewi; Wartonah; Elsa Silviani, Nadhia; Endah Pangastuti, Tri; Iriana, Pramita
Journal of Health and Cardiovascular Nursing Vol. 4 No. 2 (2024): Journal Of Health and Cardiovascular Nursing
Publisher : Politeknik Kesehatan Kemenkes RI Jakarta I

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36082/jhcn.v4i2.1984

Abstract

Hypertension control can be done by compliance with taking medication and a low-salt diet. Many people with hypertension are not compliant with taking medication and forget about a low-salt diet because they feel healthy. In fact, this should not happen because it will affect their blood pressure. The purpose of this study was to determine the relationship between compliance with taking medication and a low-salt diet with blood pressure stability in hypertensive patients. The research method used was quantitative analytical descriptive with a cross-sectional approach. The population in this study were all patients with hypertension who underwent outpatient treatment at the internal medicine. A total of 92 respondents were the sample of this study. Sampling was carried out using a purposive sampling technique. The results used chi square found that there was a relationship between medication adherence and blood pressure stability with a p-value of 0.001 and there was a relationship between a low-salt diet and blood pressure stability in hypertensive patients with a p-value of 0.001. The conclusion is that there is a relationship between medication adherence and a low-salt diet with blood pressure stability in hypertensive patients. Recommendations for patients with hypertension are advised to maintain salt intake and continue taking medication so that blood pressure remains stable.
THE INFLUENCE OF EDUCATIONAL VIDEOS ON EARLY PREVENTION OF STROKE AGAINST STROKE RISK IN THE ELDERLY Yardes, Nelly; Iriana, Pramita; Riyanti, Eska; Pangastuti, Tri Endah; Resnayanti, Yeti; Silviani, Nadhia Elsa
Jurnal Keperawatan Vol 10 No 1 (2025): May
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jkep.v10i1.1998

Abstract

Every year, 15 million people worldwide have a stroke. Education using video that are thought to be simple for the elderly to grasp can alter knowledge, attitudes, and behavior among the elderly who are at risk of stroke. This study were conducted to assess the impact of early stroke preventive education videos on stroke risk in the elderly. The method was a quasi-experimental using a non-randomized pretest-posttest control group design. This study was carried out by delivering an educational video intervention for early stroke prevention for three months and comparing the results to those of the control group or without the intervention. The population of this study was the elderly, with a sampling approach of purposive sampling and a sample size of 60 people at Posbindu in the Cipayung district. The data analysis test employed was univariate and bivariate, utilizing independent t-test to assess the effect of the instructional video intervention on early stroke prevention. The difference in the average score of knowledge (1.333; pvalue = 0.011), attitude (1.533; pvalue = 0.011), and behavior (0.466; pvalue = 0.028) in the intervention group before and after the intervention was greater than the difference in the average score of knowledge (0.233; pvalue = 0.165), attitude (0.166; pvalue = 0.484), and behavior (0.000; pvalue = 1.000) in the control group. Furthermore, the independent T-test revealed that the instructional video intervention was helpful in improving knowledge (p-value = 0.064) and attitude (p-value = 0.008). Early stroke prevention education movies improve the elderly's knowledge and attitudes.
Co-Authors Ace Sudrajat Ayu Rahmadani, Ainina Elsa Silviani, Nadhia Endah Pangastuti, Tri Lusiani, Dewi Mahanani, Munifah Syamara Malau, Paulus Hotmatua Minarma Siagian Pangastuti, Tri Endah Resnayanti, Yeti Riyanti, Eska Santa Manurung Silviani, Nadhia Elsa Sri B. Subakir Sudrajat, Ace Sumbara Suratun Sutarmo Setiadji Tri Jauhari Wartonah Wulan D.C, Tsabita Yardes, Nelly