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Potential Effects of Neem Plants (Azadirachta indica A. Juss.) as Antidiabetic Putri Rachma Novitasari; Baiq Maylinda Gemantari; Syarifatul Mufidah; Prita Anggraini Kartika Sari
Journal of Food and Pharmaceutical Sciences Vol 9, No 2 (2021): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.1938

Abstract

Many people choose alternative medicines for Diabetes Mellitus (DM) disorders, such as herbal plants to suppress the occurrence of the disease widely. In general, DM occurs when the pancreas doesn't produce enough insulin, or when the body can't effectively use the insulin which it produces. The use of medicinal plants to treat various diseases has shown minimal side effects. Indonesia is one of the countries that has used plants as traditional medicine since ancient times. In Indonesia, thousands of species of medicinal plants have been studied to address health problems. Among the medicinal plants that have been studied is the Neem plant (Azadirachta indica A. Juss) which has been shown to cure various diseases. This review article describes the potential of the Neem plant as an antidiabetic. The results of this literature review, in the form of Neem herbal extracts, have quite good potential as an antidiabetic because they contain several compounds such as meliacinolin, azachdirichtin, gliserid oil, acetyl oxyturanoe acid and other compounds that can also act as antidiabetic.
Effect of consumption of vegetables and fruit on nitric oxide levels and T-glutathione levels in type 2 diabetes mellitus patients Prita Anggraini Kartika Sari; Endang Darmawan; Akrom Akrom
Pharmaciana Vol 12, No 2 (2022): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.145 KB) | DOI: 10.12928/pharmaciana.v12i2.23322

Abstract

Glutathione is an antioxidant that plays a role in preventing free radicals and reducing oxidative stress, including in patients with type 2 diabetes mellitus (DMT2). One of the factors that affect glutathione status is the individual's ability to produce glutathione and in diabetic patients, T-glutathione levels have decreased. This study aims to determine the effect of fruit and vegetable consumption habits on plasma levels of T-Glutathione. This research method is analytic observational with cross sectional findings, the sample used is 85 subjects in the form of archives of biological materials. Data on habits of consuming vegetables and fruits were collected through interviews, plasma T-GSH levels were determined biochemically using the Elabscience GSH Assay Kit and then analyzed using the Mann Whitney test. The results showed that the average plasma T-GSH levels in patients with the habit of consuming vegetables and fruit and those who did not, were 13.54 ± 3.34 mol/L and 12.73 ± 1.44 mol/L, respectively, but not found a significant difference relationship (p = 0.222). This study provides information that the habit of consuming vegetables and fruit does not provide a significant difference to plasma T-GSH levels in T2DM patients. But these habits still need to be done for health maintenance. Further research is needed that is more specific to the amount and type of certain vegetables and fruits consumed and how to cook them.
Peningkatan Kesehatan Keluarga Melalui Pemanfaatan dan Penanaman Tanaman Obat Keluarga (TOGA) di Gampeng, Pajangan, Bantul Vella Lailli Damarwati; Muhammad Fariez Kurniawan; Radhwa Fauztina; Zhafira As Syafa; Putri Arditya; Rahmat A. Hi Wahid; Prita Anggraini
Prosiding Seminar Nasional Program Pengabdian Masyarakat 2022: 3. Kesehatan Keluarga dan Masyarakat
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Tanaman obat keluarga (TOGA) adalah jenis tanaman obat pilihan yang dapat ditanam di pekarangan rumah untuk meningkatkan kesehatan keluarga. TOGA dapat dijadikan sebagai alternatif obat tradisional yang mudah dicari, relatif murah, dan memiliki efek samping yang lebih rendah daripada obat-obatan kimia. Kegiatan pengabdian masyarakat ini bertujuan untuk memberikan penyuluhan terkait pemanfaatan TOGA untuk pengobatan tradisional dan pelatihan bagaimana mengelola lahan atau pekarangan kosong dengan menanan tanaman TOGA. Metode yang digunakan adalah ceramah untuk penyuluhan kepada masyarakat terkait TOGA serta pelatihan bagaimana teknik penanaman TOGA yang baik dan benar. Guna menilai pemahaman peserta maka peserta diberikan pretest sdan post-test sebelum dan sesudah dilakukan edukasi. Berdasarkan nilai pretest dan post-test diperoleh rata-rata masing-masing adalah 7,4 dan 8,5. Hal ini menunjukkan adanya peningkatan pemahaman peserta sebelum dan sesudah dilakukan edukasi
Kepatuhan Penggunaan Obat Antidiabetes Oral Di Puskesmas Kotagede Ii Yogyakarta Menggunakan Kuesioner Mars-10 Nurul Zahroh Oktafiani; Hamnah Al Atsariyah; Prita Anggraini Kartika Sari; Merry Ramdhani
SNHRP Vol. 5 (2023): Seminar Nasional Hasil Riset dan Pengabdian (SNHRP) Ke 5 Tahun 2023
Publisher : LPPM Universitas PGRI Adi Buana

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Abstract

Kepatuhan pengobatan, khususnya pada pasien dengan diabetes mellitus (DM) akan mempengaruhi hasil terapi. Ketidakpatuhan dapat menyebabkan kadar glukosa tidak terkontrol dan meningkatkan risiko komplikasi diabetes. Penelitian ini bertujuan untuk mengidentifikasi kepatuhan penggunaan obat pada pasien DM. Metode penelitian ini yaitu observasional deskriptif dengan pengamatan secara prospektif menggunakan teknik purposive sampling sesuai inklusi. Penelitian dilakukan pada bulan Mei 2023 di Puskesmas Kotagede II Yogyakarta menggunakan instrumen MARS-10. Data dianalisis menggunakan Microsoft Excel 2017. Hasil penelitian yang dilakukan pada 11 responden didapatkan bahwa sebagian besar responden berjenis kelamin perempuan (81,82 persen), berusia ≥ 60 tahun (63,67 persen), bekerja sebagai ibu rumah tangga (54,54 persen), terdiagnosis diabetes selama <6 tahun (63,67 persen), serta mengkonsumsi 1 obat antidiabetes oral (54,54 persen). Analisis hasil menunjukkan bahwa tidak ada satupun pasien yang mendapatkan skor 0-3 (tidak patuh), sedangkan 2 pasien mendapatkan skor 4-6 (cukup patuh), dan 9 pasien mendapatkan skor 7-10 (patuh). Kesimpulan penelitian ini yaitu responden yang patuh (81,82 persen) lebih besar daripada responden yang cukup patuh (18,18 persen).
Potential Effects of Neem Plants (Azadirachta indica A. Juss.) as Antidiabetic Putri Rachma Novitasari; Baiq Maylinda Gemantari; Syarifatul Mufidah; Prita Anggraini Kartika Sari
Journal of Food and Pharmaceutical Sciences Vol 9, No 2 (2021): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.1938

Abstract

Many people choose alternative medicines for Diabetes Mellitus (DM) disorders, such as herbal plants to suppress the occurrence of the disease widely. In general, DM occurs when the pancreas doesn't produce enough insulin, or when the body can't effectively use the insulin which it produces. The use of medicinal plants to treat various diseases has shown minimal side effects. Indonesia is one of the countries that has used plants as traditional medicine since ancient times. In Indonesia, thousands of species of medicinal plants have been studied to address health problems. Among the medicinal plants that have been studied is the Neem plant (Azadirachta indica A. Juss) which has been shown to cure various diseases. This review article describes the potential of the Neem plant as an antidiabetic. The results of this literature review, in the form of Neem herbal extracts, have quite good potential as an antidiabetic because they contain several compounds such as meliacinolin, azachdirichtin, gliserid oil, acetyl oxyturanoe acid and other compounds that can also act as antidiabetic.