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All Journal Journal of Food and Pharmaceutical Science Indonesian Journal of Chemistry Jurnal Peduli Masyarakat Journal of Food and Pharmaceutical Sciences
Mufidah, Syarifatul
Universitas Ahmad Dahlan
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Other

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Potential Effects of Neem Plants (Azadirachta indica A. Juss.) as Antidiabetic Putri Rachma Novitasari; Baiq Maylinda Gemantari; Syarifatul Mufidah; Prita Anggraini Kartika Sari
Journal of Food and Pharmaceutical Sciences Vol 9, No 2 (2021): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.1938

Abstract

Many people choose alternative medicines for Diabetes Mellitus (DM) disorders, such as herbal plants to suppress the occurrence of the disease widely. In general, DM occurs when the pancreas doesn't produce enough insulin, or when the body can't effectively use the insulin which it produces. The use of medicinal plants to treat various diseases has shown minimal side effects. Indonesia is one of the countries that has used plants as traditional medicine since ancient times. In Indonesia, thousands of species of medicinal plants have been studied to address health problems. Among the medicinal plants that have been studied is the Neem plant (Azadirachta indica A. Juss) which has been shown to cure various diseases. This review article describes the potential of the Neem plant as an antidiabetic. The results of this literature review, in the form of Neem herbal extracts, have quite good potential as an antidiabetic because they contain several compounds such as meliacinolin, azachdirichtin, gliserid oil, acetyl oxyturanoe acid and other compounds that can also act as antidiabetic.
Structure-Activity Relationship Study on the Ethyl p-Methoxycinnamate as an Anti-Inflammatory Agent Ismiarni Komala; Supandi Supandi; Nurhasni Nurhasni; Ofa Suzanti Betha; Eka Putri; Syarifatul Mufidah; Muhammad Fikry Awaludin; Mida Fahmi; Muhammad Reza; Nurkhayati Putri Indriyani
Indonesian Journal of Chemistry Vol 18, No 1 (2018)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (264.829 KB) | DOI: 10.22146/ijc.26162

Abstract

Ethyl p-methoxycinnamate (EPMC) (1) has been isolated as a major compound from the rhizome of Kaempferia galanga together with the other compound ethyl cinnamate (2). As reported in the literature, EPMC (1) exhibited a significant in vitro and in vivo anti-inflammatory activity. In this research, we investigated the anti-inflammatory activity of compounds 1 and 2 by using anti-denaturation of heat bovine serum albumin (BSA) method. In order to analyze active sites that are responsible for the anti-inflammatory activity, therefore, it is necessary to conduct structural modification of EPMC (1). The structural modification was performed through re-esterification reaction by using conventional and assistance of the unmodified microwave oven. Evaluation of the results of the bioassay indicated that the ester and methoxy functional groups of EPMC (1) play an important role for the anti-inflammatory activity.
Potential Effects of Neem Plants (Azadirachta indica A. Juss.) as Antidiabetic Putri Rachma Novitasari; Baiq Maylinda Gemantari; Syarifatul Mufidah; Prita Anggraini Kartika Sari
Journal of Food and Pharmaceutical Sciences Vol 9, No 2 (2021): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.1938

Abstract

Many people choose alternative medicines for Diabetes Mellitus (DM) disorders, such as herbal plants to suppress the occurrence of the disease widely. In general, DM occurs when the pancreas doesn't produce enough insulin, or when the body can't effectively use the insulin which it produces. The use of medicinal plants to treat various diseases has shown minimal side effects. Indonesia is one of the countries that has used plants as traditional medicine since ancient times. In Indonesia, thousands of species of medicinal plants have been studied to address health problems. Among the medicinal plants that have been studied is the Neem plant (Azadirachta indica A. Juss) which has been shown to cure various diseases. This review article describes the potential of the Neem plant as an antidiabetic. The results of this literature review, in the form of Neem herbal extracts, have quite good potential as an antidiabetic because they contain several compounds such as meliacinolin, azachdirichtin, gliserid oil, acetyl oxyturanoe acid and other compounds that can also act as antidiabetic.
Sekolah Lansia “SEGAR” Berbasis Pemanfaatan Toga dalam Pencegahan Penyakit Degeneratif Supadmi, Woro; Dania, Haafizah; Akrom, Akrom; Saputri, Ginanjar Zukhruf; Mufidah, Syarifatul; Sari, Prita Anggraini Kartika
Jurnal Peduli Masyarakat Vol 7 No 3 (2025): Jurnal Peduli Masyarakat: Mei 2025
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jpm.v7i3.6595

Abstract

Lansia merupakan kelompok usia yang rentan terhadap penyakit degeneratif, seperti hipertensi, diabetes melitus, dan hiperkolesterolemia, yang memerlukan pengelolaan jangka panjang. Di Kelurahan Wirobrajan, Yogyakarta, prevalensi penyakit ini cukup tinggi, sementara pemahaman dan keterampilan lansia dalam pengelolaan kesehatan secara mandiri masih rendah. Program pengabdian ini bertujuan meningkatkan pengetahuan dan keterampilan lansia dalam pemanfaatan Tanaman Obat Keluarga (TOGA) secara tepat guna sebagai langkah preventif dan pengendalian penyakit degeneratif. Kegiatan dilaksanakan melalui program Sekolah Lansia Segar (Sehat dan Bugar) dalam tiga sesi edukatif yang bersifat partisipatif, diikuti oleh 63 lansia anggota Majelis Tabligh Aisyiyah Ketanggungan. Hasil evaluasi menunjukkan pengetahuan peserta mengenai penyakit degeneratif, penggunaan obat dan pemanfaatan TOGA. Seluruh peserta memahami bahwa TOGA memiliki khasiat sebagai obat, namun konsistensi dalam penggunaannya masih perlu ditingkatkan. Kegiatan ini terbukti efektif dalam memberdayakan lansia untuk mengelola kesehatannya secara mandiri.
Co-Authors Akrom, Akrom Baiq Maylinda Gemantari Eka Putri Haafizah Dania Ismiarni Komala Mida Fahmi Muhammad Fikry Awaludin Muhammad Reza Novitasari, Putri Rachma Nurhasni Nurhasni Nurkhayati Putri Indriyani Ofa Suzanti Betha Prita Anggraini Kartika Sari Saputri, Ginanjar Zukhruf Sari, Prita Anggraini Kartika Supandi Supandi Woro Supadmi