Garuda - Garba Rujukan Digital

LOGAM PADUAN MAGNESIUM SEBAGAI IMPLAN BIODEGRADASI Jakfar, Subhaini
Dentika: Dental Journal Vol. 19 No. 1 (2016): Dentika Dental Journal
Publisher : TALENTA

Magnesium berpotensi digunakan sebagai bahan implan sementara dikarenakan memiliki sifat biodegradasi. Makalah ini membahas tentang logam paduan sebagai implan yang terbiodegradasi. Sifat biodegradasi ini, lebih lanjut dapat dimanfaatkan untuk diaplikasikan sebagai bahan implan permanen yaitu dapat meniadakan pembedahan tahap lanjutan untuk mengeluarkan bahan implan dari bagian tubuh setelah fungsi jaringan tubuh yang digantikannya pulih. Selama berada di dalam tubuh, magnesium mengalami degradasi dan kelarutannya ini dapat diekskresikan ke luar tubuh melalui metabolisme tanpa membahayakan tubuh (biodegradasi). Akan tetapi, meskipun memiliki sifat biodegradasi dan bioresorbable, kecepatan korosi dari logam ini menjadi permasalahan sehingga menurunkan fungsi implan sendiri yaitu mengalami degradasi sebelum jaringan tubuh yang digantikan berfungsi sempurna. Kesimpulannya, penyempurnaan untuk mengurangi kecepatan korosi telah dilaksanakan untuk memperoleh kesesuaian antara kecepatan korosi magnesium dan pengembalian fungsi tulang. Beberapa perlakuan tersebut untuk mendapatkan degradasi yang sesuai dan pembentukan tulang diantaranya melalui perlakuan mekanik, pelapisan, pengaturan komposisi paduan, serta pertimbangan sifat toksisitas dengan jaringan sekitarnya.

ROLE OF PALATAL RUGAE PATTERNS (RUGOSCOPY) IN FORENSIC FIELD: PERAN POLA RUGAE PALATAL (RUGOSKOPI) DALAM BIDANG FORENSIK Subhaini Jakfar
Dentika: Dental Journal Vol. 16 No. 2 (2011): Dentika Dental Journal
Publisher : TALENTA

The development of forensic identification in dentistry is growing significantly to serve judicial system, there are teeth, lip prints, bite marks, dental arches, dental records, DNA, palatal rugae patterns, etc., which is called forensic odontology. Another forensics identification in dentistry is restoration material used in oral cavity. All of them are used in forensic identification for disaster victim identification, criminal and research. Differences of them are allowing fast and secure identification process, however, in some cases, these techniques can not always be applied which is necessary to apply different and less known techniques. This article reviews some of the useful palatal rugae patterns as forensic identification or rugoscopy by using gypsum dental cast. The palatine rugae is an interested forensic because of its typical pattern of orientation, number, position, and size which can be used to differ ethnicity or sex, and palatine rugae is permanent and unique to each person, so it can be used to assist the forensic odontologist in the identification of a person. In conclusion, palatine rugae is significant use in clinical and forensic purposes.

PENGARUH KONSENTRASI FLUOR DAN pH PASTA GIGI TERHADAP PELEPASAN ION LOGAM DARI PERMUKAAN LOGAM PADUAN: EFFECT OF FLUORIDE CONCENTRATIONS AND pH OF TOOTH PASTE ON METAL IONS RELEASED FROM ALLOYS SURFACE Subhaini Jakfar; Poppy Andriany; Bambang Irawan; Siti Triaminingsih
Dentika: Dental Journal Vol. 15 No. 2 (2010): Dentika Dental Journal
Publisher : TALENTA

It was reported that fluoride in prophylactic agents can be detriment the oxide layers of CoCr and NiCr alloys used as dental restorations. The aim of this study was to determine the effect of fluoride concentration and pH of some commercial toothpastes in Indonesia on the ions released from CoCr and NiCr alloys surface. 120 specimens of CoCr and NiCr alloys were used in this study (60 specimens for each alloy). All specimens were mounted in resin with one side opened. Each alloy divided into 4 groups, there were 15 specimens immersed into 3 kinds of each commercial tooth paste solution (ratio 1:3) and aquabides as control solution for 1, 6, and 13 days duration,. The metal ions released into tooth paste solutions and aquabides were analyzed by AAS tool. The result of study showed that metal ions released into 3 kinds of commercial toothpastes solutions and aquabides were nickel ions from NiCr alloy only, and it was significant (p<0,05) for each aging duration. Lower pH showed higher influence to ion release than fluoride concentrations, and CoCr alloy had a better passive layer than NiCr alloy.

PROFILE OF ALLERGY HYPERPLASMA PATHOLOGIC ANTIBODY AND IMMUNOGENIC CHARACTERISTIC Nazaruddin Nazaruddin; Hamdani Budiman; Basri A. Gani; Subhaini Jakfar; M. Hasan; Muhammad Hanafiah
Jurnal Kedokteran Hewan Vol 11, No 1 (2017): March
Publisher : Universitas Syiah Kuala

The objective of this research was to determine the allergy hyperplasma pathologic antibody and to evaluate the immunogenic characteristics. Blood and serum were collected from human suffering rhinitis, skin, eye and asthma allergies. To obtain a cloned allergen plasma protein (protein allergen that had been induced with the serum from human with allergic rhinitis, skin, eye and asthma), the goat was used as an intermediate animal. Hematological analysis showed that the leukocyte cell such as neutrophil, lymphocyte, monocyte, and eosinophil increase in allergic-suffered human. The blood smear test exhibited that the mastocyte cell was dominant which contributes to allergy activities in human body. The sodium dodecyl sulphate-polyacrylimide gel electrophoresis (SDS-PAGE) assay detected protein allergens with molecular weight of 188 kDa (IgE) and 60-62 kDa (mastocyte cell). The reactivity assay using enzyme linked immunosorbent-assay (ELISA) revealed that cloned-allergens (whole hyperplasma allergen from goat isolates) express the best reactivity at various concentrations of IgE than the leukocyte cells. This research concluded that the clones of protein allergen have better immunogenic characteristic and those proteins can be recommended as the candidate of allergen to induce the humoral immunity on host and deliver specific product of anti-allergy such as milk.

Characteristics and Antibacterial Properties of Film Membrane of Chitosan-Resveratrol for Wound Dressing Basri A. Gani; Nur Asmah; Cut Soraya; Dharli Syafriza; Sri Rezeki; Muhammad Nazar; Subhaini Jakfar; Nurtami Soedarsono
Emerging Science Journal Vol 7, No 3 (2023): June
Publisher : Ital Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28991/ESJ-2023-07-03-012

The research aimed to evaluate the film membrane of Nano Chitosan Resveratrol (NCHR) for biological, physicochemical, and antibacterial properties. Psychochemically, the functional groups of chitosan compounds were examined by FTIR, chemical compounds by GCMS, and the morphology of chitosan and chemical elements by SEM-EDS. Biologically, the characteristics of NCHR were examined by solubility, swelling, permeability, and biodegradation tests. Meanwhile, the antibacterial properties were examined for inhibition of Porphyromonas gingivalis (P. gingivalis) ATCC 33277 by Minimal inhibition concentration (MIC) and growth assessment by spectrophotometry. Nano Chitosan (NCH) has appeared at 1033.85 cm-1 as a sharp peak indicating the P=O group and contains anti-toxicity compounds (Ethane, 1,1-diethoxy- (CAS) 1,1-Diethoxye) is 81.06% and antioxidant compounds Limonene is (1.28%). In addition, NCH has chemical elements, Oxygen Weight (69.4%), calcium (19.7%), magnesium (6.6%), and phosphorus (4.3%). NaCl 0.9%, PBS, and Aquades. In addition, it has an excellent index of water vapor transmission rate (WVTR) in all solvents (R2³ 0.95). The NCHR membrane film is bacteriostatic (≤ 300 CFU/mL) with each value of Minimal Inhibition Concentration (MIC) >15 mm. The Nano chitosan contains antitoxic, antioxidant, and antibacterial compounds with high oxygen elements. The film membrane of nano chitosan resveratrol can maintain the stability of changes in pH with a very high solubility index, swelling index, and WVTR index, as well as good biodegradation and antibacterial properties. Doi: 10.28991/ESJ-2023-07-03-012 Full Text: PDF

PROFILE OF ALLERGY HYPERPLASMA PATHOLOGIC ANTIBODY AND IMMUNOGENIC CHARACTERISTIC Nazaruddin, Nazaruddin; Budiman, Hamdani; Gani, Basri A.; Jakfar, Subhaini; Hasan, M.; Hanafiah, Muhammad
Jurnal Kedokteran Hewan Vol 11, No 1 (2017): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v11i1.5299

The objective of this research was to determine the allergy hyperplasma pathologic antibody and to evaluate the immunogenic characteristics. Blood and serum were collected from human suffering rhinitis, skin, eye and asthma allergies. To obtain a cloned allergen plasma protein (protein allergen that had been induced with the serum from human with allergic rhinitis, skin, eye and asthma), the goat was used as an intermediate animal. Hematological analysis showed that the leukocyte cell such as neutrophil, lymphocyte, monocyte, and eosinophil increase in allergic-suffered human. The blood smear test exhibited that the mastocyte cell was dominant which contributes to allergy activities in human body. The sodium dodecyl sulphate-polyacrylimide gel electrophoresis (SDS-PAGE) assay detected protein allergens with molecular weight of 188 kDa (IgE) and 60-62 kDa (mastocyte cell). The reactivity assay using enzyme linked immunosorbent-assay (ELISA) revealed that cloned-allergens (whole hyperplasma allergen from goat isolates) express the best reactivity at various concentrations of IgE than the leukocyte cells. This research concluded that the clones of protein allergen have better immunogenic characteristic and those proteins can be recommended as the candidate of allergen to induce the humoral immunity on host and deliver specific product of anti-allergy such as milk.

Title

Found 6 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 6 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 6 Documents
Search