Vera Julia
Department Of Oral And Maxillofacial Surgery, Faculty Of Dentistry, Universitas Indonesia

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Desmoplastic Fibroma and Cemento Ossifying Fibroma of The Anterior Maxilla: A Rare Case Report: Desmoplastic Fibroma dan Cemento Ossifying Fibroma: Laporan Kasus Langka Victor Pakpahan; Eky Nasuri; Vera Julia
Dentika: Dental Journal Vol. 24 No. 1 (2021): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/dentika.v24i1.5613

Abstract

Tumors located in the maxillofacial part of the body were classified by WHO in 2017 and among these are intraosseous form of fibromatosis known as Desmoplastic and Cemento-ossifying fibromas. These tumors usually occur in the head and neck region, especially in the mandible and are relatively rare in the maxilla. Meanwhile, this study aims to discribe a rare case of the cemento ossifying fibroma that had been previously diagnosed as desmoplastic fibroma with a mass tumor in the anterior of the maxilla. A 22 years old female reported to the Cipto Mangkusumo Hospital with the main complaint of a lump in the right side of the upper jaw which appeared 2 years prior to the operation. In April 2017, the patient had a biopsy in Tarakan Hospital and the result was a desmoplastic fibroma. Due to the lump enlargement, the patient was admitted to RSCM in July 2019 and had biopsy incision with a diagnosis of cemento ossifying fibroma which was confirmed by the histopathological examination and histology report. The resection of the right part of maxilla was conducted alongside with reconstruction using the free fibular flap. Moreover, cemento ossifying fibroma and desmoplastic fibroma shared similar features, namely, clinical, histological and radiological features which are important in establishing the diagnosis and treatment of patient. Hence, extensive enucleation or resection is required due to the progressive nature of the tumor to prevent the potential for further recurrences.
Mandibulektomi segmental dengan rekonstruksi cangkok tulang fibula non-vaskularisasi pada pasien ameloblastoma tipe folikulerSegmental mandibulectomy with non-vascularised fibular bone graft reconstruction in follicular ameloblastoma patient Rumartha Putri Swari; Arfan Badeges; Vera Julia
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 32, No 3 (2021): Februari 2021 (Suplemen 2)
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v32i3.31485

Abstract

Pendahuluan: Ameloblastoma adalah tumor invasif lokal dengan insidensi kekambuhan yang tinggi jika tidak dieksisi sepenuhnya. Mandibulektomi segmental sebagai pilihan tatalaksana yang dapat menyebabkan deformitas dan asimetri pada wajah, serta masalah pengunyahan. Pemulihan defek setelah reseksi mandibula menimbulkan masalah yang cukup berat. Tujuan laporan kasus ini untuk melaporkan hasil rekontruksi menggunakan cangkok tulang non-vaskularisasi mandibulektomi segmental pada pasien dengan ameloblastoma mandibula. Laporan kasus: Pria berusia 33 tahun datang ke Poliklinik Rawat Jalan Bagian Bedah Mulut dan Maksilofasial RS Persahabatan dengan keluhan utama pembengkakan mandibula yang perlahan bertambah dan tidak nyeri sejak enam tahun lalu. Pemeriksaan ekstra oral tampak asimetri wajah, bukaan mulut tidak ada limitasi, tidak teraba pembesaran kelenjar getah bening regio leher. Pemeriksaan intraoral didapatkan adanya benjolan regio mandibula kiri dengan batas tegas, konsistensi padat, permukaan tampak trauma oklusi gigi antagonis, immobile, dan terdapat nyeri tekan. Gambaran radiologis menunjukan lesi radiolusen multilokuler menyerupai honeycomb pada corpus mandibula kiri meluas ke regio ramus mandibula kiri. Pemeriksaan biopsi menunjukkan hasil ameloblastoma tipe folikuler pada mandibula kiri dan dilakukan mandibulektomi segmental dengan rekonstruksi cangkok tulang fibula non-vaskularisasi. Sembilan bulan setelah operasi, cangkok tulang non-vaskularisasi tidak menunjukkan komplikasi intraoral dengan bekas luka submandibular ekstraoral baik. Simpulan: Cangkok tulang fibula non-vaskular dapat dipertimbangkan sebagai salah satu pilihan untuk rekonstruksi setelah mandibulektomi segmental pada pasien ameloblastoma.Kata kunci: Mandibulektomi segmental, cangkok fibula non-vaskularisasi, ameloblastoma folikuler. ABSTRACTIntroduction: Ameloblastoma is a locally invasive tumour with a high incidence of recurrence if not completely excised. Segmental mandibulectomy as a treatment option that can cause facial deformities and asymmetry and mastication problem. Recovery of the defect after mandibular resection presents a severe problem. This case report was aimed to report the results of reconstruction using a segmental non-vascularised mandibulectomy bone graft in a patient with mandibular ameloblastoma. Case report: A 33-year-old male came to the Outpatient Polyclinic of the Oral and Maxillofacial Surgery Division of Persahabatan General Hospital with the chief complaint of mandibular inflammation, which was slowly increasing yet painless since six years prior. Extraoral examination showed facial asymmetry, no limitation in mouth opening, no palpable enlargement of lymph nodes in the neck region. Intraoral examination revealed a lump in the left mandibular region with firm borders, solid consistency. The surface appears to be traumatic occlusion of the antagonist tooth, immobile, and tenderness was found. Radiological features showed a multilocular, honeycomb-like radiolucent lesion on the left mandibular body extending into the left mandibular ramus region. A biopsy showed follicular ameloblastoma in the left mandible, and a segmental mandibulectomy was performed with non-vascular fibular bone graft reconstruction. Nine months after surgery, non-vascular bone grafts showed no intraoral complications with either extraoral submandibular scar. Conclusion: Non-vascular fibular bone graft can be considered an option for reconstruction after segmental mandibulectomy in ameloblastoma patients. Keywords: Segmental mandibulectomy, non-vascularised fibula graft, follicular ameloblastoma.
Effect of coral Goniopora Sp scaffold application on human osteoblast-like MG-63 cell activity in vitro Julia, Vera; Abbas, Basril; Bachtiar, Endang W; Latief, Benny S; Kuijpers-Jagtman, Anne M
Makara Journal of Health Research Vol. 23, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Coral is an osteo-conductive biomaterial that can act as an alternative scaffold for osteogenesis. In this in vitro study we analyzed the activity of osteoblast-like cells after treatment with the coral Goniopora. Methods: Human osteoblast-like MG-63 cells were incubated in α-minimal essential medium supplemented with 10% fetal bovine serum and 300 ng/mL amphotericin B plus 1% penicillin-streptomycin and stored in a 5% CO2 incubator at 37°C. The Goniopora were smashed into size A (20 mesh), B (1–2 mm), and C (200 mesh) particles, sterilized using gamma radiation and applied to cells. Protein and alkaline phosphatase (ALP) concentrations were evaluated after incubation for 24 and 48 h. Results: The protein assay of 24 h and 48 h cultured osteoblasts illustrated that treated cells, whether with coral size A, B and C exhibited a lower mean value compared to the untreated cells. For ALP levels there were statistically significant differences at 48 h between B and C (p = 0.004), and A and C (p = 0.09). Conclusions: No significant differences in total protein concentrations were found among all groups after 24 and 48 h. Smaller coral size and longer incubation time tended to facilitate osteogenesis. These results require further empirical validation.
Management of keratocystic odontogenic tumor in the maxillary sinus of 12-year-old children: A case report Hendy U. Suhandi; Yudy A. Utomo; Eky Nasuri; Vera Julia
Journal of Dentomaxillofacial Science Article In Press
Publisher : DiscoverSys Inc.

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Abstract

Objective: Keratocystic odontogenic tumor (KCOT) is a benign intraosseous tumor of odontogenic origin, making up the third most common odontogenic cyst. KCOTs arise from the remnants of dental lamina or the basal cells of the overlying oral epithelium. KCOTs are characterized by an aggressive behaviour with a relatively high recurrence rate, especially if they are associated with syndromes. Treatment of KCOTs include marsupialization, saucerization, Methods: A 12-year-old child patient was referred to the Specialist Clinic of Oral and Maxillofacial Surgery, Cipto Mangkusumo Hospital. On physical examination, facial asymmetry, a fixated swelling and lump in right maxilla from the second molar to canine with tenderness were observed. A complete history was taken and clinical examination followed by complete enucleation with sulcular flap from 12 region until 18 regions was performed. The diagnosis was maxillary dentigerous cyst based on histopathological result after the operation. Results: The medical history was not significant and patient was in a generally good condition with no fever, nausea, pain, or difficulty in breathing. Extra oral examination showed facial asymmetry and visible lump in the right region of the maxilla. Conclusion: The diagnosis of maxillary KCOT expanding to maxillary sinus can be achieved with adequate datas; history, clinical, and histopathological examinations. Careful surgical approach and proper treatment decision is crucial to avoid complications according to individual case of each patient, especially in children.
The use of resorbable plate in complex pediatric parasymphysis fracture management: A rare case report Andrianto Soeprapto; Fitriana; Vera Julia; Dwi Ariawan
Journal of Dentomaxillofacial Science Article In Press
Publisher : DiscoverSys Inc.

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Abstract

Objective: The use of open reduction and internal fixation with resorbable plate is the best management for complex pediatric mandibular fractures as the potential growth and development of the mandibular. The most common resorbable plate in Indonesia is ®inion plate. Case Report: A 6 year old girl fell off her bicycle on a downhill road 30 minutes before the hospital admission. Comminuted basal triangle fracture of left mandibular parasymphysis from 3DCT imaging was found. Open reduction and internal fixation with resorbable plate and monocortical screws was performed from extraoral and intraoral approach. Conclusion: Management of complex pediatric parasymphysis fracture require ORIF with plating on inferior border of mandibular and using monocortical screws to avoid any damage to nearby tooth buds. The resorbable plates give good outcome and advantage in pediatric patients as their potential growth and development of the mandibular.
Local advancement flap: A case report Syarief Makka; Hendro Sunjaya; Eky Nasuri; Vera Julia
Journal of Dentomaxillofacial Science Article In Press
Publisher : DiscoverSys Inc.

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Abstract

Objective: A local flap, including an advancement flap, is useful for covering large skin defects on the head and neck. The incision of the advancement flap is carefully made to cover the main defect as efficiently as possible. Methods: A 34 years old female patient was referred to Department of Oral and Maxillofacial Surgery, Cipto Mangunkusumo National Central General Hospital and had a mandibular resection, extraction of tooth 45, and left condyle disarticulation, followed by fistulectomy, debridement, and squesterectomy. For closing the defect, a local advancement flap was made, the flap was incised, reduced, and pulled to wraparound the main site of the defect. Result: The local advancement flap combined with Burrow’s triangle design, result in complete closure of the defect and also has a maximum cosmetic appearance. Conclusion: Unipedicle-pedicle advancement flaps involve advancement by taking benefit of the skin elasticity, the advancement flap is also done by making an incision of the Burrow-triangles design subsequently bringing the skin laterally to level the length of the flap and the adjacent wound margin.
Neglected fracture of bilateral mandibular corpus: A case report Wayan HS. Sandi; Wenny Yulvie; Yudy A. Utomo; Vera Julia; Lilies D. Sulistyani
Journal of Dentomaxillofacial Science Article In Press
Publisher : DiscoverSys Inc.

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Objective: This paper aimed to report the management of neglected bilateral mandibular corpus fracture with open reduction and fixation technique. Method: A 38-year-old male patient was referred to Dr. Cipto Mangunkusumo Hospital with chief complaints can not close the mouth and chewing food properly. The patient had a history of injured in motor vehicle accidents, 3 months ago. Extra oral examination showed facial asymmetry, while in ntra oral examination revealed anterior open bite malocclusion. In orthopantomogram (OPG) image, fracture lines in bilateral mandibular corpus were seen. Results: The fractures were managed with Open Reduction Internal Fixation (ORIF) using reconstruction plates to reestablished the occlusion and facial asymmetry. Postoperative evaluation showed good occlusion and facial symmetrical without injured the mental nerve. Conclusion: Early and proper management of bilateral mandible corpus fracture will provide the optimum result. Refracturing the neglected bilateral mandibular corpus is treatment choice in order to restore the mastication and aesthetic function.
Cemento-ossifying fibroma of the jaw: A case report Moara GP. Yudha; Wenny Yulvie; Vera Julia
Journal of Dentomaxillofacial Science Article In Press
Publisher : DiscoverSys Inc.

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Objective: The purpose of this case report is to evaluate the treatment plan for the following patients. The definite diagnosis of these lesions requires the integration of their clinical, radiological and histological characteristics. Methods: For 8 years ago, a 52-year-old female patient initially felt an increase in the mouth of the left lower jaw. The lumps are initially the size of a marble and then expand like a ping-pong ball. The lumps are painless. Before the mass, there was no history of trauma in this area. There is no history of fever and no history of weight loss. The patient underwent a biopsy of the left mandible at Dr. Cipto Mangunkusumo National Central Public Hospital in September 2019. Results: Cemento ossifying fibroma. The lumps in the cheek gums extend to the lingual area of ​​teeth 35-37, the size is 6x5x4cm, the texture is hard, the surface is smooth, the boundary is not clear, not fixed, there is no tenderness, and the color and temperature are the same as the surrounding tissues. The lump does not bleed easily, and there is no discharge of pus or blood. The patient's treatment plan was to perform a segmental mandibular resection with a 2.4 mm reconstruction plate. Conclusion: The treatment planning for segmental mandibulectomy in general anesthesia is one of the right treatment options. Choosing a submental submandibular approach to the surgical procedure can provide easy access and visualization during surgery.
Gambaran lesi ossifying fibroma mandibula pada CBCT Mustafa, Resky; Priaminiarti, Menik; Julia, Vera; Bachtiar, Hanna
MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM Vol 9, No 2 (2023)
Publisher : Fakultas Kedokteran Gigi, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mkgk.82273

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Ossifying fibroma (OF) merupakan suatu neoplasma jinak berkapsul yang dianggap sebagai jenis lesi fibroosseous (FOL) yang terdiri dari berbagai jumlah tulang yang terkalsifikasi dan menyerupai sementum dalam stroma fibrosa. Lesi ini biasanya ditemukan pada wanita dengan rentan segala usia namun paling sering terjadi pada decade ketiga dan ke empat kehidupan. Secara radiografik gambaran lesi OF yang bervariasi tergantung pada tingkat mineralisasi dan waktu perkembangan lesi. Lesi radiolusen unilocular dengan densitas campuran atau lesi radiopak dengan batas yang jelas atau radiolusen tipis seperti kapsul fibrosa yang dapat mengakibatkan ekspansi. Seorang pasien wanita berusia 20 tahun, datang dengan keluhan utama gigi bungsu atas dan bawah tidak tumbuh sempurna. Gusi kanan bawah kadang dirasakan sakit dan ada keterbatasan membuka mulut. Pasien menyadari ada asimetri wajah ± 3 bulan yang lalu. Pada pemeriksaan klinis menunjukkan adanya benjolan di corpus mandibula kanan yang minimal, tidak terasa sakit dan tidak tampak tanda-tanda peradangan. Pada pemeriksaan intraoral didapatkan #47 erupsi sebagian. Dilakukan eksisi biopsi dan ekstraksi #47. Diagnosis pasien ini adalah ossifying fibroma jenis juvenile yang terjadi pada usia dewasa muda dengan rencana perawatan eksisi biopsy dan ekstraksi #47. Pemeriksaan CBCT dapat memperlihatkan secara komprehensif gambaran lesi dan pembahasan diagnosis banding lesi.
Neglected zygomaticomaxillary complex fracture: Report of two cases during the COVID-19 pandemic Ananda, Nissia; Ariawan, Dwi; Julia, Vera
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 3 (2024): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i3.p221-227

Abstract

Background: The COVID-19 pandemic spread rapidly worldwide, including in Indonesia. As a result, people developed a fear of visiting hospitals and a tendency to ignore symptoms unrelated to COVID-19. A zygomaticomaxillary complex bone fracture is one of the most frequent midface fractures and is often accompanied by infraorbital nerve paresthesia. Purpose: This article aims to report two cases of neglected zygomaticomaxillary complex bone fractures with persistent infraorbital nerve paresthesia caused by the patient’s fear of seeking medical care. Cases: The first case is a 19-year-old male with a history of trauma two weeks prior to hospital admission. He was diagnosed with a neglected zygomaticomaxillary complex bone fracture, which resulted in persistent infraorbital nerve paresthesia. This condition was due to the patient’s fear of visiting the hospital. The second case is a 21-year-old female who presented with a history of persistent numbness on the left cheek and upper lip for one month prior to hospital admission. The symptoms originated from an accident where the patient fell from a ladder measuring two meters in height. Case management: Surgical intervention—open reduction and internal fixation (ORIF)—was performed on both patients to promote nerve recovery. However, there is ongoing debate regarding the safety of elective oral maxillofacial surgery procedures during the COVID-19 pandemic. After a follow-up period, both patients experienced a recovery of sensory function in the infraorbital nerve. Conclusion: Infraorbital nerve sensory disturbance along with zygomaticomaxillary complex bone fracture found during the COVID-19 pandemic should be managed with ORIF to improve nerve recovery.