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HUBUNGAN SINDROM METABOLIK DENGAN KEJADIAN DISFUNGSI EREKSI PADA PASIEN PRIA DIABETES MELITUS TIPE 2 DI POLIKLINIK PENYAKIT DALAM RSUP SANGLAH DENPASAR Ni Putu Tesi Maratni
E-Jurnal Medika Udayana vol 5 no 3(2016):e-jurnal medika udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (247.937 KB)

Abstract

ASSOCIATION OF METABOLIC SYNDROME WITH ERECTILE DYSFUNCTION IN TYPE 2 DIABETES MELLITUS MEN PATIENTS AT INTERNAL MEDICINE OUTPATIENT CLINIC OF SANGLAH GENERAL HOSPITAL DENPASARErectile dysfunction (ED) is a commonly chronic complication among men with type 2 diabetes mellitus (T2DM). The associated factor of diabetes-induced erectile dysfunction is metabolic syndrome. This research is designed to observe the relationship of metabolic syndrome and ED in T2DM patients. This cross sectional study has 34 consecutive samples and is conducted at Internal Medicine Outpatient Clinic of Sanglah Hospital in November and December 2013. ED is diagnosed based on The International Index of Erectile Function 15 (IIEF 15) questionnaire. Metabolic syndrome is diagnosed based on revised NCEP ATP III criteria. Demographic data and laboratory results are taken from medical records. Data are analyzed by chi square bivariate test. The results showed metabolic syndrome does not correlate significantly with ED among T2DM patients (p=0.913; 95% CI 0.082–10.228).
Effect of Porang (Amorphophallus muelleri Blume) Flour Diet on Postprandial Blood Sugar Rates and Insulin Resistance in Male Wistar Rats (Rattus norvegicus) Diabetes Mellitus Nathasia; Widhiartini, Ida Ayu Alit; Dwipayana, I Made Pande; Wahyuni, Nila; Maratni, Ni Putu Tesi; Hendrayana, Made Agus
HAYATI Journal of Biosciences Vol. 33 No. 1 (2026): January 2026
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.33.1.95-102

Abstract

Medical nutrition therapy is essential in diabetes management, especially as diabetes is often linked with aging. Porang tuber flour contains glucomannan, a compound with potential glucose-lowering effects. This study aimed to evaluate the effect of porang flour feeding frequency on 2-hour postprandial blood glucose (2hPPBG) and HOMA-IR in diabetic rats. Using a quasi-experimental pre-test and post-test control group design, 21 male Wistar rats were induced with diabetes via streptozotocin and nicotinamide, then randomly assigned to three groups: G0 (control, given aquadest), G1 (porang flour 300 mg/kg BW daily), and G2 (porang flour 300 mg/kg BW every two days). Five rats died during treatment. Wilcoxon test results showed a difference in 2hPPBG levels between each group before and after treatment. There was no decrease in G0 (p = 0.893), but a decrease in G1 (p = 0.043) and G2 (p = 0.028). The difference between HOMA-IR before and after treatment did not decrease in groups G0 (p = 0.345), G1 (p = 0.138), and G2 (p = 0.249). Post hoc test for 2hPPBG levels between groups showed a significant difference between G0 and G1 (p<0.001), a significant difference between G0 and G2 (p<0.001), and no significant difference between G1 and G2 (p = 0.135). One-way ANOVA test of HOMA-IR showed no significant difference between G0, G1, and G2 (p = 0.148). It was concluded that porang flour can reduce 2hPPBG, but not HOMA-IR. There was no difference in 2hPPBG levels between administering porang flour daily and every other day.