Article Per Year (5 Year)
p-Index From 2021 - 2026
1.116
P-Index
This Author published in this journals
All Journal Jurnal Ilmu keperawatan Journal of the Medical Sciences (Berkala Ilmu Kedokteran) The Indonesian Biomedical Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Osman Sianipar
Department Of Clinical Pathology And Laboratory Medicine, Faculty Of Medicine, Public Health And Nursing, Universitas Gadjah Mada / Dr. Sardjito Hospital, Yogyakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 24 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 24 Documents
Search

 1   2   3 
Diagnostic Performance of Molecular Rapid Test in Establishing Diagnosis of MDR-TB Nunung Dartini Wahyuningtyas; Osman Sianipar; Andaru Dahesihdewi
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 28 No. 2 (2022)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v28i2.1843

Abstract

Tuberculosis (TB) is a global health problem and is the leading cause of morbidity and mortality in many developing countries.   Multi Drug Resistant Tuberculosis (MDR TB) becomes one burden of health problems considering the high morbidity and mortality rates. Establishment of MDR TB diagnosis is still a challenge, related to the tools and methods used, while cultural examination as  gold standard is expensive and takes a long time. This study aims to evaluate diagnostic performance  of Molecular Rapid Test or MRT (GeneXpert) in establishing diagnosis of MDR TB  using Mycobacteria Growth Indicator Tube (MGIT) culture as gold standard. Using a cross sectional design, this study involved 51 subjects, a total of 26 (51%) male and 25 (49%) female, adult patients suspected TB, treated at dr. Ario Wirawan Lung Hospital (RSPAW) Salatiga.  Mean age 48.2 + 16.35 years, (17-79 years). The MRT for TB and MDR TB detection showed 13 and 7 true positives, 32 and 43 true negatives; obtained 68.4% and 87.5% Sensitivity, 100% and 100% Specificity, 100% and 100% Positive Predictive Value (PPV),  84.2% and 97.7% Negative Predictive Value (NPV), respectively. A specific analysis to diagnose MDR TB by MRT on TB patient groups showed 7 true positives, 0 false positives, 11 true negatives and 1 false negative;   obtained  87.5% Sensitivity, 100% Specificity, 100% PPV and 91.7% NPV.  For establishing diagnosis of MDR TB, MRT provides perfect specificity.  One false negative MDR TB in MRT results is likely resistant to other than rifampicin.
Blood Culture Positivity Rate: Antibiotical Therapy Impact Before Sample Collection in Sepsis Patients Sri Kartika Sari; Andaru Dahesihdewi; Osman Sianipar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 29 No. 3 (2023)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v29i3.2016

Abstract

Sepsis is one of the significant causes of global morbidity and mortality. One of the keystones of sepsis diagnosis and treatment is the Blood Culture (BC) test. BC performed after intravenous Antibiotic Administration (AA) appears to reduce the culture positivity rate. This study aimed to evaluate the influence of AA before obtaining blood culture samples on the positivity rate. This was a retrospective cohort study, conducted from January to February 2020 on patients with suspected sepsis at the Mataram General Hospital from January to December 2019. Patients with valid blood culture tests were included. Out of 178 suspected sepsis patients, 138 samples were culture-negative, and 40 samples were culture-positive. Out of 40 culture-positive patients, 23 (57.5%) samples were obtained before AA, whereas other 17 samples (42.5%) were obtained after AA. In addition, among 138 culture-negative patients, 101 (73.2%) subjects received antibiotics before sampling, and only 37 (26.8%) subjects received antibiotics after sampling. There was a significant difference in the blood culture positivity results between samples taken before and after AA (p=0.001). Samples were taken before AA had a 3.69 times greater possibility of positive culture results than samples taken after AA (OR 3.69; 95% CI 1.77-7.67; p= 0.0005). The percentage of positive culture results among subjects receiving antibiotics before sampling was highest (20%) in those whose samples were taken less than an hour before the next AA. Antibiotics administration of sepsis patients before blood culture sampling gives a lower positivity rate than AA after blood culture sampling.
The Ovarian Cancer Clinical Aspects and at least Two Tumor Markers for Diagnosis Laboratory Examination Dwi Yulia; Osman Sianipar Sianipar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 30 No. 1 (2023)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v30i1.2114

Abstract

Ovarian cancer is one of the gynecological malignancies with a bad outcome. Epidemiologically, it is the fifth cause of death in females worldwide. Patients have various complaints, and examinations available for early detection are inadequate, causing high mortality rates and late diagnosis. Prepare a more appropriate examination to establish an earlier diagnosis, especially in females with risk factors requiring screening. Laboratory examinations combined with other supporting examinations can provide better results to confirm the diagnosis of ovarian cancer and lower the morbidity rate. Knowing the updated examination to support the diagnosis, such as examination of ovarian cancer biological markers specific to HE4, CA-125, CEA, CA 19-9. A combination of examinations is needed for early detection of ovarian cancer.
Albumin-Bilirubin Score as A Predictor of Mortality in Patients with Hepatocellular Carcinoma -, Sagita Adventia; -, Umi Solekhah Intansari; Sianipar, Osman
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 32 No. 1 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v32i1.2710

Abstract

 An Albumin-Bilirubin (ALBI) score was developed as a tool to assess liver function. Still, its application in clinical practice particularly as a predictor of mortality in hepatocellular carcinoma (HCC)—remains limited. This study aimed to evaluate the ALBI score as a prognostic factor for mortality in patients with HCC. A retrospective cohort study was conducted, involving HCC patients treated at Dr. Sardjito General Hospital, Yogyakarta, from January 2017 to December 2021. Patients with HCC who had an Eastern Cooperative Oncology Group (ECOG) performance status score of 0–2 and available albumin and bilirubin data at the time of diagnosis were included. Subjects were classified into three groups based on ALBI grade: grade I (score ≤ -2.60), grade II (score> -2.60 to ≤ -1.39), and  grade III (score > -1.39). The exposed group consisted of subjects with ALBI grade II and grade III, while those with ALBI grade I were classified as the unexposed group. Follow-up was conducted for two years after diagnosis, with death as the primary outcome. Survival analysis was performed using the Kaplan-Meier method and the log-rank test. Hazard ratios (HRs) were analyzed using Cox regression.  A p-value of <0.05 was considered statistically significant. The study included 35 subjects with ALBI grade I, 78 with ALBI grade II, and 54 with ALBI grade III. The risk of mortality for subjects with ALBI grade II and grade III was 2.27 and 2.32 times higher, respectively, compared to those with ALBI grade I.
Co-Authors -, Sagita Adventia -, Umi Solekhah Intansari . Fatrinawati . Fatrinawati . Windarwati Adang Muhammad Andaru Dahesihdewi Bambang Suryono, Bambang Benuriadi Benuriadi Budi Mulyono Christantie Effendy Dewi Indah Noviana Pratiwi Dwi Aryani Dwi Yulia Dyah Artini Emy Noerwidayati Endro Basuki Guardian Yoki Sanjaya Indah Kartika Murni Iwan Dwiprahasto Luz Maria GBW Mohammad Rizki Nunung Dartini Wahyuningtyas Oktania Candrawati Sri Kartika Sari Suwarso Suwarso Umi S Intansari Usi Sukorini Widya Asmara