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All Journal Microbiology Indonesia Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati PROSIDING SEMINAR KIMIA BERITA BIOLOGI Jurnal Penelitian Pembelajaran Fisika ACCOUNTHIK : Journal of Accounting and Finance
Praptiwi Praptiwi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Immunology & microbiology Medicine & Pharmacology Physics Social Sciences

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Uji Aktivitas Antibakteri dan Sitotoksik Ekstrak Metanol Aglaia silvestris (M.Roemer) Merr. Praptiwi Praptiwi
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 12, No 1 (2007): February 2007
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v12i1.2532

Abstract

The antibacterial and sitotoxic activities of ganggo (Aglaia silvestris (M.Roemer) Merr. methanol extract were determined in this study. Antibacterial in-vitro test of ganggo methanol extract was exposed to Gram positive (Staphylococcus aureus ATCC 25923, Streptococcus agalactiae ATCC 8190, and Streptococcus sp.) and Gram negative (Salmonella typhii NCTC 786 E, Eschericia coli ATCC 25922, and Pseudomonas pseudomallei ATCC 15682) bacteria. The extract concentrations were 50, 25 and 12.5%, and done in triplicate. The growth inhibition area of extract was compared to those of standard antibiotic (10 unit ampicilin). Cytotoxic test of ganggo extract was done utilizing Brine Shrimp Lethality Test (BST) with Artemia salina.The result showed that growth inhibition area of 12.5% ganggo methanol extract to P. pseudomallei (19 mm) was wider than that of 10 unit ampicilin (0 mm). It showed that P. pseudomallei was sensitive to ganggo methanol extract. The result of BST showed that LC50 of ganggo extract was 345.44 ppm. It was concluded that ganggo methanol extract had antibacterial effects on some bacteria isolates and had cytotoxic effects with LC50 345.44 ppm.
Pengaruh Pemberian Ekstrak Kulit Batang Ailanthus altissima terhadap Perubahan Sel Hati dan Ginjal Mencit Praptiwi Praptiwi; Emma Sri Kuncari; Dewi Ratih Agungpriyono; Chairunnisa Chairunnisa
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 15, No 1 (2010): February 2010
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v15i1.2654

Abstract

The aim of this study was to determine the toxicopathological effect of Ailanthus altissima extract in liver and kidney of the mouse. The treatments in this study were: (1) negative control (carboxy methocellulose), extracts with concentration of (2) 1 mg/kg BW, (3) 10 mg/kg BW, (4) 100 mg/kg BW, and (5) 1000 mg/kg BW. Every treatment consisted of 5 mice. After receiving A.altissima extract for seven day consecutively, the mice were then euthanized with overdose of ether. The liver and kidney were taken and then fixed within 10% solution of Buffer Neutral Formalin (BNF). Histopathology slides of liver and kidney were processed and stained with Hematoxylline Eosin. The cell degeneration and cell death were observed with video photo microscope. The lesion of cell death and degeneration of hepatocytes and epithelium of kidney proximal tubule were counted. The data were analyzed statistically with ANOVA test continued with Duncan test. The result showed that cell necrosis of hepatocytes was not significantly different (P>0.05) compared to control treatment, while cell necrosis was increasing in the treatment of ≥ 10 mg/kg BW in tubuli of the kidney.
Aktivitas Antibakteri Ekstrak Metanol Buah Mbosi (Dysoxylum gaudichandianum (A.Juss) Miq.) dan Penapisan Senyawa Kimianya Praptiwi Praptiwi; Mindarti Harapini
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2005): June 2005
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.2844

Abstract

Mbosi (Dysoxylum gaudichandianum (A.Juss) Miq.) belongs to Meliaceae family, Its potential bioactivity had not been known although the other plants from the same family had been known as natural insectiside or medicinal plants. Phytochemical screening showed that mbosi fruit contained fat, fatty acid, sterol, triterpenoide, tannin, peroxide sugar, alkaloid, steroid glycoside and flavonoid. Identification of mbosi fruit chemical compounds by GC-MS showed that it contained 16 compounds. Compounds with the concentration more than 5 % were butyl cellosolve (11.1%), erythritol (8.48%), glycerol (10.32%), hexadecanioc acid palmitinic ester (16.2%), oleic acid (65.3%) and ethyl oleat (6.2%).  In-vitro antibacterial test on innoculated Mueller Hinton Agar to seven bacteria isolates (Salmonella typhimurium, S. typhii, Eschechiria coli ATCC 25923, Pseudomonas sp., Staphylococcus aureus ATCC 25922, S. epidermidis, and Bacilus subtilis)  showed that 20% methanol extract  inhibit only the growth of  Staphylococcus aureus.
SKRINING AKTIVITAS ANTIBAKTERI DAN ANTIOKSIDAN EKSTRAK TUMBUHAN SCHOUTENIA OVATA KORTH. (WALIKUKUN) Kartika Dyah Palupi; Praptiwi Praptiwi; Andria Agusta
PROSIDING SEMINAR KIMIA Prosiding SNKT Himpunan Mahasiswa Kimia FMIPA UNMUL 2021
Publisher : PROSIDING SEMINAR KIMIA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Schoutenia ovata Korth. atau Walikukun merupakan tumbuhan yang banyak ditemukan di Indonesia. Kayu dari tumbuhan ini digunakan oleh masyarakat sebagai gagang perkakas dan juga sebagai bahan kerajinan tangan. Namun demikian, hingga saat ini, penelitian mengenai potensi farmakologis Walikukun belum dieksplorasi lebih jauh. Oleh karena itu, pada penelitian kali ini dilakukan skrining aktivitas antibakteri dan antioksidan dari daun dan batang Walikukun yang dikoleksi dari Mandalika, Nusa Tenggara Barat. Simplisia kering dari daun dan batang Walikukun diekstraksi secara bertingkat dengan pelarut n-heksana, diklorometan, etil asetat dan metanol. Analisis profil kimia dari daun dan batang Walikukun dilakukan dengan metode kromatografi lapis tipis. Uji aktivitas antibakteri dilakukan terhadap Staphylococcus aureus dan Escherichia coli sedangkan uji aktivitas antioksidan dilakukan terhadap radikal bebas 1,1-diphenyl-2-picrylhydrazyl (DPPH). Penentuan kadar hambat minimum (KHM) antibakteri serta penentuan indeks aktivitas antioksidan (IAA) dilakukan dengan metode mikrodilusi. Hasil pengamatan menunjukkan bahwa ekstrak daun dan batang dari Walikukun menunjukkan aktivitas antibakteri yang lemah hingga moderat dengan nilai KHM terendah sebesar 128 µg/ml. Ekstrak batang Walikukun menunjukkan aktivitas antioksidan yang potensial. Ekstrak metanol batang Walikukun menunjukkan aktivitas antioksidan terbaik dengan nilai IAA 8.275 ± 0.012 (aktivitas antioksidan sangat kuat). Hasil penelitian ini menunjukkan bahwa batang Walikukun merupakan sumber senyawa antioksidan yang potensial.Kata kunci: Schoutenia ovata Korth., Staphylococcus aureus, Escherichia coli, DPPH
AKTIVITAS ANTIBAKTERI DAN ANTIOKSIDAN EKSTRAK IXORA CUMINGIANA Kartika Dyah Palupi; Praptiwi Praptiwi; Dewi Wulansari; Andria Agusta
BERITA BIOLOGI Vol 19, No 1 (2020)
Publisher : Research Center for Biology-Indonesian Institute of Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/beritabiologi.v19i1.3777

Abstract

Plants from Ixora genus exhibit a variety of pharmacological activities including antioxidant, antibacterial, and antitumor activities. This plants may contain many interesting bioactive compounds, especially phenolics and terpenoids groups. Ixora cumingiana is one of the Ixora species whose pharmacological effect has not been explored comprehensively. This study aimed to evaluate the antibacterial and antioxidant activity of eight extracts from bark and leaf of I. cumingiana. The plant samples were successively extracted using n-hexane, dichloromethane, ethyl acetate and methanol. The antibacterial evaluation was carried out against Staphylococcus aureus and the antioxidant activity was evaluated using a radical scavenging assay against 1,1-diphenyl-2-picrylhydrazyl (DPPH). Initial activity screening was performed using thin layer chromatography-bioautography followed by the determination of minimum inhibitory concentration (MIC) and the determination of antioxidant activity index (AAI) using microdilution technique. The dichloromethane extract of the bark as well as the n-hexane and dichloromethane extract of the leaf of I. cumingiana exhibited moderate antibacterial effect with MIC value of 128, 128, and 256 µg/ml, respectively. The methanol extract from the bark displayed a strong antioxidant activity (AAI = 1.5±0.13) and possessed the highest total phenolic content (43±0.91 mg AGE/ g extract). These experimental results showed that I. cumingiana is potential to be developed as an antioxidant agent rather than as an antibacterial agent. 
KOMPONEN KIMIA DAN UJIANTIBAKTERIMINYAK ATSIRIDAUN KI CENGKEH (Urophyllum arboreum (Reinw. ex. Bl.) Korth.) Praptiwi Praptiwi; Yuliasri Jamal; Tri Murningsih
BERITA BIOLOGI Vol 6, No 3 (2002)
Publisher : Research Center for Biology-Indonesian Institute of Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/beritabiologi.v6i3.1218

Abstract

This study was done to determine the chemical compounds and antibacterial activity of ki cengkeh (Urophyllum arboreum (Reinw.ex. Bl.) Korth.) essential oil. Ki cengkeh has already known as medicinal plant in some places in Indonesia. This might be correlated with its chemical compounds. The analysis of chemical compounds of ki cengkeh essential oil was done by GC-MS, while antibacterial test was done by paper disc method against 3 bacteria isolates (Staphylococcus aureus, S. epidermidis and Eschericia coli). The result of GC-MS analysis showed that there were 25 compounds with the concentration more than 1% and carryophylen oxide as the highest compound (12.03%). The highest antibacterial activity was found against S. epidermidis.
AKTIVITAS ANTIBAKTERI EKSTRAK KULTUR JAMUR ENDOFIT Fusarium sp. CSP-4 YANG DIISOLASI DARI Curcuma sumatrana Miq. Dewi Wulansari; Ersaliany Nurul Pratiwi Qodrie; Bodhi Dharma; Andi Saptaji Kamal; Lukman Hafid; Lina Marlina; Praptiwi Praptiwi
BERITA BIOLOGI Vol 19, No 1 (2020)
Publisher : Research Center for Biology-Indonesian Institute of Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/beritabiologi.v19i1.3350

Abstract

Endophytic fungus Fusarium sp. CSP-4 was isolated from the rhizome of Curcuma sumatrana Miq. The ethyl acetate extract of CSP-4 was fractionated by chromatographic column with silica as a stationary phase. The fractions were tested for antibacterial activity against S.aureus and E.coli by Thin Layer Chromatography (TLC)- bioautography. Determination of Minimum Inhibitory Concentration (MIC) was carried out by the microdilution method on a 96-microwell plate with the concentrations from 2 to 256 µg/ml. The results showed that fraction 15 and 11 were able to inhibit bacterial growth with the MIC values of 256 and> 256 μg / mL against S.aureus and>256 μg / mL against E.coli, respectively.The antibacterial activity of fractions 15 and 11 was weaker compared to the positive control of chloramphenicol with the MIC value of 4 µg/mL against S.aureus and E.coli. Based on the results obtained showed that the fractions of the methanol extract of endophytic fungus Fusarium sp. CSP-4 have weak antibacterial activity. 
SKRINING AWAL AKTIVITAS ANTIBAKTERI DAN ANTIOKSIDAN EKSTRAK SEMUT (INSECTA: FORMICIDAE) DARI GARUT - JAWA BARAT Oscar Efendy; Ahmad Fathoni; Praptiwi Praptiwi; Mohammad Fathi Royyani; Dewi Wulansari; Andria Agusta
BERITA BIOLOGI Vol 18, No 2 (2019)
Publisher : Research Center for Biology-Indonesian Institute of Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/beritabiologi.v18i2.3621

Abstract

Studies on the therapeutic use of insects and insect products have been neglected compared to the use of other animals or plants.This study aims to determine the antibacterial and antioxidant potential of ants extracts. Preliminary study related to antibacterial and antioxidant screeningof 17 extracts of ant colonies that belongs to 8 species were performed by Thin Layer Chromatography (TLC)-Bioautography. Antioxidant activity was measured by DPPH free radical scavenging method. The antibacterial activity was done against three pathogenic bacteria, i.e Bacillus subtilis InaCC B-1, Staphylococcus aureus InaCC B-4 and Escherichia coli InaCC B-5 were performed by non-eluted TLC-autobiography assay. The minimum inhibitory concentration (MIC) and IC50 values of DPPH radical scavenging activity of active extracts were determined by microdilution in 96-well microplate. The results showed 6 extracts active against B.subtilis, 5 extracts active against S.aureus. The lowest MIC value was 512 µg/ ml.  Ten extracts had the antioxidant activity with various IC50 values. The extracts of ants might be used as bioactive resources for antibacterial and antioxidant.  
EFEKTIVITAS METODE KOOPERATIF TIPE GI DAN STAD DITINJAU DARI KEMAMPUAN AWAL Praptiwi Praptiwi; Jeffry Handhika
Jurnal Penelitian Pembelajaran Fisika Vol 3, No 1 (2012): APRIL 2012
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/jp2f.v3i1/april.384

Abstract

Penelitian ini bertujuan untuk mengetahui: 1) Perbedaan penggunaanmetode pembelajaran kooperatif tipe GI dan STAD terhadap prestasibelajar fisika. 2) Perbedaan kemampuan awal tinggi dan kemampuanawal rendah terhadap prestasi belajar fisika. 3) Interaksi antarametode pembelajaran dan kemampuan awal siswa terhadap prestasibelajar fisika. Jenis penelitian ini adalah eksperimen. Populasi dalampenelitian ini adalah semua siswa SMPN 1 Barat. Sebagai sampeldiambil dua kelas sebanyak 68 siswa yang kemudian dijadikan kelaseksperimen I dan kelas eksperimen II. Kelas VIIIB sebanyak 34 siswasebagai kelas eksperimen I diberikan pendekatan menggunakanmetode pembelajaran kooperatif tipe GI sedangkan kelas VIIIDsebanyak 34 siswa sebagai kelas eksperimen II diberikan pendekatanmenggunakan metode pembelajaran kooperatif tipe STAD denganteknik pengambilan sampel cluster random sampling. Teknik analisisdata yang digunakan adalah analisis variansi (anova) dua jalan.Hasilpenelitian dengan ?Ä?? = 5% dapat disimpulkan bahwa: (1) Metodekooperatif tipe GI lebih baik daripada metode kooperatif tipe STADdengan Fhitung = 92,77. (2) Siswa dengan kemampuan awal tinggimempunyai prestasi belajar fisika yang lebih baik dibandingkandengan siswa yang mempunyai kemampuan awal rendah dengan Fhitung = 4,199. (3) Ada interaksi antara metode pembelajaran dankemampuan awal siswa terhadap prestasi belajar fisika (F hitung =5,16), metode GI dan STAD cenderung berinteraksi pada kemampuanawal rendah.Kata kunci : Metode GI, STAD, Kemampuan Awal, Prestasi Belajar
Peran Economic Order Quantity dalam Manajemen Persediaan Bahan Baku (Studi pada UD. Nurisma tahun 2016) Dianita Meirini; Praptiwi Praptiwi
Accounthink Vol 2 No 02 (2017)
Publisher : UNSIKA (Universitas Singaperbangsa Karawang)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.066 KB) | DOI: 10.35706/acc.v2i02.918

Abstract

This research aims to determine the role of the inventory management method, Economic Order Quantity (EOQ) in decision making for the amount of economic ordering and cost efficiency of raw material inventory. EOQ method is very effective applied to companies that have a high quantity of annual inventory. UD. NURISMA is a manufacturing company producing “krupuk uyel mentah” with annual demand of raw material is high enough, which is 3,423 sacks in 2016. This research was conducted at UD NURISMA for inventory cost efficiency and the determination of order quantity economical raw material inventory of “krupuk uyel mentah”. This research is a quantitative descriptive research and using raw material inventory data at UD. NURISMA which includes data on the quantity of raw material requirements, data of ordering cost and raw material storage data during 2016. This study compares raw material inventory management based on UD. NURISMA policy with EOQ inventory management.The result of this research is EOQ inventory management method is able to give efficiency of inventory cost equal to Rp 3,082,502, -. The cost efficiency is obtained from the difference between inventory cost based on UD NURISMA policy (Rp. 9.338.178,-), toward inventory cost with EOQ (Rp. 6.255.676,-). Researchers suggest UD. NURISMA to use the Economic Order Quantity (EOQ) method. Implementation of EOQ method provides benefits for the company to know how much raw materials to be ordered and when to make a re-order.
Co-Authors AHMAD FATHONI Andi Saptaji Kamal ANDRIA AGUSTA Andria Agusta ARIEF NURKANTO Bodhi Dharma Chairunnisa Chairunnisa Dewi Ratih Agungpriyono Dewi Wulansari Dewi Wulansari Dianita Meirini Emma Sri Kuncari Ersaliany Nurul Pratiwi Qodrie Jamhari Jamhari Jeffry Handhika Kartika Dyah Palupi Kartika Dyah Palupi Lina Marlina Lukman Hafid MINDARTI HARAPINI Mohammad Fathi Royyani Oscar Efendy Tri Murningsih YULIASRI JAMAL