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All Journal Media Penelitian dan Pengembangan Kesehatan Universa Medicina
Nunik Kusumawardani
Pusat Teknologi Intervensi Kesehatan Masyarakat, Badan Litbangkes, Kemenkes RI, Jl. Percetakan Negara No. 29 Jakarta, Indonesia
Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Universa Medicina

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Central obesity increases the risk of type 2 diabetes mellitus among urban adults Pradono, Julianty; Kusumawardani, Nunik; Delima, Delima
Universa Medicina Vol 34, No 3 (2015)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2015.v34.187-196

Abstract

BackgroundIn Indonesia the number of persons with type 2 diabetes mellitus (T2DM) was 8.5 million in 2013, and is estimated to be 11.8 million in 2030. The aim of this study was to determine the major risk factors associated with T2DM prevalence in urban aged >15 years.MethodsAn observational study with cross-sectional design was used with the data from Riskesdas 2007 and 2013 on population aged >15 years. Total respondents were 294,352 (2007) and 368,281 (2013). Data were collected by trained personnel through interviews, blood pressure and anthropometry measurements, and blood glucose and lipid tests. Odds ratio (OR) was used to test the relationship between T2DM and a number of other variables. Multiple logistic regression analysis was obtained to determine the main risk factor associated with T2DM prevalence.ResultsType 2 diabetes mellitus prevalence increased from 2.3% (2007) to 2.5% (2013). T2DM tended to be increased in the younger age groups. Low education, middle-to-high economic status, less physical activity, smoking >200 cigarettes, and high risk blood lipid levels were strongly associated with T2DM prevalence. The main risk factors were inadequate physical activity (2007: OR 1.9;95% CI:1.16–2.98 and 2013: OR 2.44;95% CI: 1.57-3.78) and central obesity (2007: OR 1.8;95% CI:0.99–3.10, and 2013:OR 3.84; 95% CI: 2.49-5.93) after controlling for age, gender, employment and economic status.ConclusionsType 2 diabetes mellitus prevalence in the population aged >15 years increased within 5 years. Lack of physical activity and central obesity were the major risk factors of T2DM prevalence in urban adults.
Determinants of diabetes comorbidities in Indonesia: a cohort study of non-communicable disease risk factor Kristanti, Dewi; Rahajeng, Ekowati; Sulistiowati, Eva; Kusumawardani, Nunik; Dany, Frans
Universa Medicina Vol. 40 No. 1 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.3-13

Abstract

BackgroundType 2 diabetes mellitus (DM) is a non-communicable disease that constitutes a huge health burden, with the presence of comorbidities of DM adding to it. This study aimed to obtain the main determinants of the combined incidence of DM and its main comorbidities in adults.MethodsThis was a further analysis of the Non-Communicable Disease Risk Factor Cohort Study 2011 – 2018 involving 3730 subjects. Data of diabetes-free respondents at baseline were followed up every 2 years for 6 years. Data collection was carried out through interviews and health examinations. All subjects were assayed for blood glucose and lipid parameters. Chi-square test and Cox regression were implemented for data analysis.ResultsDuring 6 years of follow-up, DM incidence occurred in 567 (15.2%) subjects. The most common comorbidities were increased low density lipoprotein (LDL), central obesity, increased total cholesterol, obesity and hypertension. Most of the comorbidities occurred before the diagnosis of DM incidence. The determinants of the combined DM incidence–increased LDL are obesity, hypertension, and a family history of DM. The determinants of the combined DM incidence–central obesity are increased triglycerides, hypertension, male gender, and family history of DM. While the determinants of the combined DM incidence–hypertension are obesity and increased triglycerides.CONCLUSIONThis study demonstrated a high burden of diabetes incidence with comorbidities among adults. Knowledge of the magnitude of the diabetescomorbidity determinants emphasizes the role of non pharmacological intervention such as weight reduction and dietary modification.
Co-Authors Delima Delima Dewi Kristanti Dwi Hapsari Ekowati Rahajeng Eva Sulistiowati Frans Dany, Frans Ika Dharmayanti Julianty Pradono Puti Sari H