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All Journal e-GIGI e-Journal Pustaka Kesehatan Jurnal Ilmu Kesehatan Masyarakat ODONTO Dental Journal Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Dental Journal (Majalah Kedokteran Gigi) Jurnal Penelitian Kesehatan Suara Forikes Health Notions Journal of Dentomaxillofacial Science Interdental Jurnal Kedokteran Gigi (IJKG) Odonto dental journal
Yuliana Mahdiyah Daat Arina
Bagian Periodonsia Fakultas Kedokteran Gigi Universitas Jember
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Library & Information Science Medicine & Pharmacology Nursing Public Health

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The evaluation of mandibular bone density in chronic periodontitis models Yuliana Mahdiyah Da’at Arina; F. Ferdiansyah; Mohamad Rubianto
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 4 (2018): December 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (404.756 KB) | DOI: 10.20473/j.djmkg.v51.i4.p210-215

Abstract

Background: Bone density, an important factor in functional bone quality, can affect the success of implant osteointegration or orthodontic treatment. A number of studies report that chonic periodontitis constitutes one risk factor of osteoporosis characterized by low bone mineral density and that the mandible is susceptible to osteoporosis. Purpose: The purpose of this study was to evaluate mandibular bone density in animal subjects suffering from chronic periodontitis. Methods: 40 male Wistar rats were divided into four chronic periodontitis groups and four control groups (each group n=5). As chronic periodontitis models, the subjects were injected with 2×109 CFU/ml of Porphyromonas gingivalis in the sulcular gingiva, whereas control group members were injected with normal saline. After 2, 3, 4 and 6-week injection periods, the subjects were sacrificed and radiographic examination of the mandibular bone subsequently performed. Mandibular bone density was evaluated by histometric analysis. Results: The mandibular bone density in members of the chronic periodontitis group was significantly lower than those of the control group (p<0.05). The reduced mandibular bone density in the chronic periodontitis group was in line with the protracted bouts of periodontitis. Conclusion: Reduced mandibular bone density was found in the chronic periodontitis model. The longer the duration of a bout of chronic periodontitis, the greater the reduction in mandibular bone density.
Regulation of caspase-3 expression to maintain fetal growth in Porphyromonas gingivalis-infected pregnant rats Banun Kusumawardani; Yuliana MD Arina; Azham Purwandhono
Journal of Dentomaxillofacial Science Vol. 1 No. 1 (2016): (Available online: 1 April 2016)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v1i1.16

Abstract

Periodontal disease has been involved in a variety of systemic disorders and suspected as a potential risk factor for fetal growth restriction. Periodontal pathogenic bacteria may actively regulate embryonic development, implantation and placental trophoblast cell invasion. This study aimed to analyze the role of TNF-α, IL-10 and caspase-3 to maintain fetal growth in Porphyromonasgingivalis-infected pregnant rats. Female rats were infected with live-Porphyromonas gingivalis at concentration of 2x109 cells/ml into subgingival sulcus area of the maxillary first molar before and during pregnancy. They were sacrificed on gestational day (GD)-14 and GD20. The weight and length of placentas and fetuses were evaluated. The expression of TNF-α, IL-10 and caspase-3 in macrophages and trophoblast cells were detected by immunohistochemistry. On GD14, TNF-α (R2=0.416;P=0.000) and IL-10 (R2=0.187;P=0.012) had an important role to increase expression of caspase-3 in the placenta, but only TNF-α (R2=0.393;P=0.000 ) was able to increase the expression of caspase-3 on GD20. TNF-α and caspase-3 also had an important role (P<0.000) to decrease fetal weight, fetal length and placental weight on GD14 and GD20, but it was not the case with IL-10 (P>0.000). The increasing expressions of TNF-α and IL-10 did not only enhance immune protection, but also maintained the trophoblast cells survival by regulating expression of caspase-3. Porphyromonas gingivalis infection in maternal periodontal tissue can lead to decrease in placental weight, fetal weight and fetal length which mediated by increasing expression of TNF-α, IL-10 and caspase-3 in the placenta. 
The effect of Porphyromonas gingivalis induction on neutrophil’s superoxide production Nahdiya Fitriyana; Yuliana MD Arina; Happy Harmono; IDA Susilawati
Journal of Dentomaxillofacial Science Vol. 12 No. 3 (2013): Formerly Jurnal Dentofasial ISSN 1412-8926
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v12i3.370

Abstract

Microbicidal mechanism with producing free radical superoxide is one of neutrophil response to the bacterialinvasion. When overproducted, the free radical superoxide greater than antioxidan defense system and destroyed thecell itself. P.gingivalis had been knowed as the major bacteria that induce periodontal inflammation. These bacteriacan stimulated neutrophil activities. This was aimed to determinate the superoxide production from neutrophilstimulated with P.gingivalis. Neutrophil as samples were isolated from subject who fulfill the selected criteria. Theintracelluler superoxide production was determinated by nitroblue tetra zolium (NBT)test and the extracellulerproduction by spectrophotometer with wave length 580 nm. The result showed there was superoxide production fromneutrophil stimulated by P.gingivalis. It was concluded that the stimulation of P.gingivalis on neutrophil can promotesuperoxide production both intracelluler and extracelluler.
Management of Localized Gingival Overgrowth in Patient under Fixed Orthodontic Treatment: A Case Report Neira N. Sakinah; Yuliana M. D. Arina; Depi Praharani; Peni Pujiastuti; Desi S. Sari; Melok A. Wahyukundari
e-GiGi Vol. 10 No. 2 (2022): e-GiGi
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/eg.v10i2.40683

Abstract

Abstract: Recently, the need for orthodontic treatment has increased along with the increasing need and public awareness of the importance of dental and oral health. During treatment, problems sometimes occur with periodontal tissue. Orthodontic devices that bond to the tooth surface can cause difficulties in controlling plaque, especially in marginal areas which can cause inflammation and gingival overgrowth. Too high tensile strength and weak tissue capacity are also the factors that can cause gingival overgrowth. This case report described the management of gingival growth in a patient under fixed orthodontic treatment. We reported an 18-year-old female patient with a good systemic condition that had gingival overgrowth localized on the anterior part of mandibula. The surgical intervention was performed by using conventional surgical methods. Its goal was to remove the gingival pocket, therefore, the plaque could be easily controlled. The use of a scalpel was considered very effective for eliminating excessive gingiva. Two weeks after surgical treatment, the gum resulted in good repair. The continuity of orthodontic treatment could be achieved properly after 3-month surgical treatment. Instructions and motivation to maintain oral hygiene were important to avoid recurrence. In addition, multidisciplinary dentistry between orthodontist and periodontist was needed to achieve a better result. Keywords: gingival overgrowth; gingivectomy; orthodontic appliance
Daya Hambat Pasta Gigi yang Mengandung Ekstrak Biji Kopi Robusta (Coffea canephora) terhadap Pertumbuhan Bakteri Porphyromonas gingivalis Ayu Tri Wulandari; Yuliana Mahdiyah Daat Arina; Peni Pujiastuti
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 14, No 1 (2023): Januari 2023
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf14106

Abstract

Porphyromonas gingivalis is one of the bacteria that causes periodontal disease. Toothpaste containing robusta coffee beans can be developed for the prevention and treatment of periodontal disease, because robusta coffee beans have antibacterial potential. The purpose of this study was to evaluate the antibacterial effect of robusta coffee bean extract toothpaste on the growth of Porphyromonas gingivalis bacteria. This research was an in vitro experimental research. Robusta coffee beans were extracted using the maceration method and formulated into toothpaste with a concentration of 6.25%; 12.5%; 25%; and 50%. Furthermore, an antibacterial test was carried out using the well-diffusion method on MHA media that had been inoculated with Porphyromonas gingivalis and the diameter of the inhibition zone formed around the wells was measured. The results showed that the zone of inhibition around the wells of the toothpaste was robusta coffee bean extract with a concentration of 12.5%; 25%; and 50%. The largest inhibition zone was indicated by toothpaste containing 50% concentration of robusta coffee bean extract, namely 19.18 + 0.18 mm. The higher the concentration of Robusta coffee bean extract, the greater the inhibition zone formed. It can be concluded that toothpaste containing robusta coffee bean extract is able to inhibit the growth of Porphyromonas gingivalis bacteria so that it can be developed as a toothpaste for the prevention and treatment of periodontal disease.Keywords: anti-bacterial; robusta coffee bean extract; toothpaste; Porphyromonas gingivalis ABSTRAK Porphyromonas gingivalis merupakan salah satu bakteri penyebab penyakit periodontal. Pasta gigi yang mengandung biji kopi robusta dapat dikembangkan untuk pencegahan dan perawatan penyakit periodontal, karena biji kopi robusta memiliki potensi antibakteri. Tujuan dari penelitian ini adalah untuk mengevaluasi efek antibakteri pasta gigi esktrak biji kopi robusta terhadap pertumbuhan bakteri Porphyromonas gingivalis. Penelitian ini adalah penelitian eksperimental in vitro. Biji kopi robusta diekstrak menggunakan metode maserasi dan diformulasikan menjadi pasta gigi dengan konsentrasi 6,25%; 12,5%; 25%; dan 50%. Selanjutnya dilakukan uji antibakteri menggunakan metode difusi sumuran pada media MHA yang telah diinokulasikan Porphyromonas gingivalis dan dilakukan pengukuran diameter zona hambat yang terbentuk di sekitar lubang sumuran. Hasil penelitian menunjukkan bawa zona hambat di sekitar lubang sumuran pasta gigi ekstrak biji kopi robusta konsentrasi 12,5%; 25%; dan 50%. Zona hambat terbesar ditunjukkan oleh pasta gigi yang mengandung ekstrak biji kopi robusta konsentrasi 50% yaitu 19,18 + 0,18 mm. Semakin tinggi konsentrasi ekstrak biji kopi robusta, semakin besar juga zona hambat yang terbentuk. Dapat disimpulkan bahwa pasta gigi yang mengandung ekstrak biji kopi robusta mampu menghambat pertumbuhan bakteri Porphyromonas gingivalis sehingga dapat dikembangkan sebagai pasta gigi untuk pencegahan dan perawatan penyakit periodontal.Kata kunci: anti bakteri; ekstrak biji kopi robusta; pasta gigi; Porphyromonas gingivalis
NUMBER OF BLACK-PIGMENTED ANAEROBIC BACTERIA CONTAINED IN THE GINGIVAL CREVICULAR FLUID (GCF) OF PATIENTS SUFFERING FROM THE CHRONIC PERIODONTITIS AND AGGRESSIVE PERIODONTITIS Depi Praharani; Peni Pujiastuti; Melok Aris Wahyukundari; Yuliana Mahdiyah Daat Arina; Desi Sandra Sari
Odonto : Dental Journal Vol 8, No 1 (2021): July 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (574.238 KB) | DOI: 10.30659/odj.8.1.101-107

Abstract

Health Status and Periodontal Care Needs of Pregnant Women in the Puger Coastal Area of Jember Intan Nurun Azhria; Yuliana Mahdiyah Daat Arina; Melok Aris Wahyukundari; Kiswaluyo
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 20 No. 2 (2024): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v20i1.7123

Abstract

Introduction: Pregnancy is a risk factor for periodontal disease due to an increase in hormones which causes a change in response of periodontal tissue to the accumulation of plaque and calculus that can increase the occurrence of inflammation of the gingiva and periodontal disease. Pregnant women in coastal areas have a high risk of periodontal disease because the majority consume seafood that contains high calcium and phosphorus, which allows for increased calculus formation. Periodontal disease during pregnancy has an adverse impact on the health of the fetus. Therefore, it is important to pay attention to the health of the periodontal tissues of pregnant women. This study aims to examine the description of health and periodontal treatment needs in pregnant women in the coastal area of Puger, Jember. Material and Methods: This type of research is descriptive observational with a cross sectional study on 70 subjects selected by purposive sampling technique. Data were obtained based on the results of the Community Periodontal Index of Treatment Needs (CPITN) examinations and questionnaire interviews regarding oral health. Results and Discussions: Health status of periodontal tissues of pregnant women in the coastal area of Puger Beach mostly (75,71%) had supra or subgingival calculus (CPITN score 2), there were periodontal pockets and there were no pregnant women with healthy periodontal tissue conditions. Types of periodontal treatment needs that are needed by all pregnant women are scaling and root planing and improving oral hygiene (Treatment Needs/TN 2).  Conclusion: Pregnant women in the coastal area of Puger Beach all experience periodontal disease so they need periodontal treatment.
Co-Authors Ayu Tri Wulandari Azham Purwandhono Banun Kusumawardani Depi Praharani Desi S. Sari Desi Sandra Sari Ermita Windya Pratiwi F. Ferdiansyah Happy Harmono IDA Susilawati Intan Nurun Azhria Kiswaluyo Koeswadji Koeswadji Melok A. Wahyukundari Melok Aris Wahyukundari Mohamad Rubianto Muhammad Nurul Amin Nahdiya Fitriyana Neira N. Sakinah Nihla Fitriyani Peni Pujiastuti Peni Pujiastuti Rina Sutjiati S. Sunardhi Widyaputra Tantin Ermawati Utama Bramanto Satrya Dimas