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PERBEDAAN EFEKTIFITAS ANTIBAKTERI ANTARA EKSTRAK DAUN SIRIH MERAH (Piper crocatum) DAN EKSTRAK DAUN SIRIH HIJAU (Piper betle L.) TERHADAP Porphyromonas gingivalis Dwianggraini W, Riezki; Pujiastuti, Peni; Ermawati, Tantin
STOMATOGNATIC- Jurnal Kedokteran Gigi Vol 10, No 1 (2013)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

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Almost people in the world got periodontal disease. It is about 50 % of adult population. Porphyromonas gingivalis (P. gingivalis) is anaerobic negative gram bacteria and played role in periodontitis, especially chronic periodontitis. Periodontal disease can be prevented by decreasing of plaque accumulation with oral rinse. Oral rinse can use traditional herbal, such as green and red betel leaf. Aim of this study was to know difference of antibacterial effectivity of green (piper betle l) and red (piper crocatum) betel leaf extract toward P. gingivalis. This research used well diffusion methods. There used 24 samples and divided 3 groups. First group used red betel leaf extract, second group used green betel leaf extract and third group used sterile aquadest. The samples were incubated for 24 hours in room temperature 37Â°C. Then, they were measured by inhibition zone by calipers. The result showed diameters of inhibition zone of green betel leaf was larger than red betel leaf and sterile aquadest. One way Anova test showed there was significant difference between the groups. The conclusion showed green betel leaf extract had antibacterial activity more than red betel leaf extract toward P. gingivalis.

HUBUNGAN KADAR GLUKOSA DARAH DENGAN PERTUMBUHAN A. actinomycetemcomitans PADA TIKUS DIABETES MELITUS Ermawati, Tantin
STOMATOGNATIC- Jurnal Kedokteran Gigi Vol 9, No 1 (2012)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

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Diabetes mellitus is a systemic disease characterized by insulin deficiency. Common symptoms in people with diabetes is elevated blood glucose is called hyperglycemia. Manifestations in the oral cavity are inflammation of gingival tissue or periodontitis. The bacteria that play a role in the severity of periodontal disease is A. actinomycetemcomitans. The purpose of this study was to determine the relationship of blood glucose levels with the growth of A. actinomycetemcomitans in DM rats treated with insulin therapy. Methode 20 three month old male Wistar rats with weight of 170-200 grams were divided into two groups. First, periodontitis and DM were manipulated into all groups through aloksan injection with dose of 170 mg/kg. Those rats in group I were treated with insulin, those in group II were without treatment. In the third and seventh weeks, the blood glucose levels and the number of A. actinomycetemcomitans was measured. The data was tested by using Pearson test. The results showed that there is a strong relationship between blood glucose levels with the growth of A. actinomycetemcomitans. Conclusion: The increasing blood glucose levels are very strongly associated with an increase in the number of A. actinomycetemcomitans and otherwise in DM rats with insulin therapy.

STATUS KESEHATAN PERIODONTAL DAN TINGKAT KEBUTUHAN PERAWATAN PASIEN YANG DATANG KE KLINIK PERIODONSIA RSGM UNIVERSITAS JEMBER TAHUN 2011 Ermawati, Tantin; Sari, Desi Sandra; Melok, M
STOMATOGNATIC- Jurnal Kedokteran Gigi Vol 9, No 2 (2012)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

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The CPITN is a screening procedure for identifying actual and potential problems posed by periodontal disease. The aim of this study was to know periodontal status and periodontal treatment needs from patient that come to RSGM department periodontia faculty of dentistry Jember University in the year 2011. The study population comprised 191 adolescences (10 â 59 years). An observational study was conducted at RSGM of Jember University. The results of the study showed that individuals with a health periodontium is 1.05 %, score (1) with bleeding on probing is 3.14 %. Periodontal pocket (4-5mm) was recorded 17.27 %. The highest periodontal score is scores 2 (calculus) 78.53% of the population need dental scaling. We conclude that prevalence periodontal disease in patients that come to periodontics department is very high and periodontal treatment need with scaling.

STATUS KEBERSIHAN MULUT DAN KESEHATAN PERIODONTAL PASIEN YANG DATANG KE KLINIK PERIODONSIA RSGM UNIVERSITAS JEMBER PERIODE AGUSTUS 2009 â AGUSTUS 2010 Praharani, Depi; Ermawati, Tantin; Pujiastuti, Peni
STOMATOGNATIC- Jurnal Kedokteran Gigi Vol 8, No 3 (2011)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

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Level of oral hygiene have a close relationship with periodontal health status; where good oral hygiene will minimize the occurrence of periodontal disease. Aims of this study were to assess the oral hygiene status and periodontal health patients that come to Department of Periodontics of Jember University Dental Hospital at August 2009 until August 2010. This type of research is an observational study of clinical (cross sectional). A total of 155 sample (87 males and 66 females) were examined by using Oral Hygiene Index-Simplified (OHI-S) and Periodontal Index. Good oral hygiene was seen in 11% of total sample examined, 54,2% had fair oral hygiene and rest 34,8% showed poor oral hygiene. 0,6% of total sample examined had healthy periodontal, 18,1% had simple gingivitis, 41,3% had initial of periodontal disease destructive, 37,45 had periodontal disease destructive and 2,6% had terminal disease. Oral hygiene status and periodontal health examination revealed that majority of sample had fair oral hygiene and periodontal disease destructive.

PERIODONTITIS DAN DIABETES MELITUS Ermawati, Tantin
STOMATOGNATIC- Jurnal Kedokteran Gigi Vol 9, No 3 (2012)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

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Periodontitis is a chronic infection disease caused by periodontopathogen bacteria in the oral cavity. Severity of periodontitis can be affected by systemic diseases such as diabetes mellitus. Diabetes mellitus is occurred metabolic disruption that is characterized by hyperglycemia due to insulin deficiency. Increasing blood glucose levels can lead to manifestations in the oral cavity in the form of inflammation of the gingival tissue, attachment loss and alveolar bone destruction. Periodontitis is one of the sixth complications of diabetes mellitus. There are inter- related relationship between periodontitis and diabetes mellitus.

Daya Hambat Ekstrak Biji Kopi Robusta (Coffea robusta) terhadap Pertumbuhan Fusobacterium nucleatum Hakima, Anisa Nur; Ermawati, Tantin; Harmono, Happy
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 15 No 2 (2018)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v15i2.17932

Fusobacterium nucleatum is a bacteria found in normal flora of the oral cavity that plays a role in the occurrence of periodontal disease. The prevalence of periodontal disease in Indonesia reaches 70%. One treatment by using medicinal plants is robusta coffee beans. Robusta coffee beans contain volatile acids, chlorogenic acids, caffeine acids, phenols and caffeine suspected to be antibacterial. The objective of this study was to determine the inhibition of coffee robusta extract on growth of Fusobacterium nucleatum. This study used disc diffusion method with 4 samples in each study group. The study group consisted of 6 treatment groups (12,5%, 25%, 50% and 100% coffee robusta extract), positive control group (chlorhexidine gluconate 0,2%), and negative control group (sterile aquades). Data were analyzed using One Way Anova test and LSD (Least Significant Difference) test. Coffee robusta extract has the ability to inhibit the growth of Fusobacterium nucleatum. The concentration of coffe robusta extract 100%, 50%, 25%, 12,5% have same ability to inhibit the growth of Fusobacterium nucleatum.

Efek Gel Ekstrak Biji Kopi Robusta (Coffea canephora) terhadap Jumlah Sel Makrofag dan Limfosit Jaringan Gingiva Tikus Periodontitis Ermawati, Tantin; Prasetya, Rendra Chriestedy; Fatimatuzzahro, Nadie; Nurul Iffah, Astrid Ganadya
Insisiva Dental Journal: Majalah Kedokteran Gigi Insisiva Vol 9, No 2 (2020)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/di.9217

Periodontitis adalah inflamasi kronis yang disebabkan infeksi bakteri salah satunya P. gingivalis. Produk bakteri berupa lipopolisakarida (LPS) mampu meningkatkan sekresi sitokin proinflamatori sehingga terjadi peningkatan jumlah sel makrofag dan limfosit. Hal ini menyebabkan kerusakan jaringan periodontal yang lebih lanjut. Biji kopi robusta memiliki kandungan polifenol, alkaloid dan saponin yang berfungsi sebagai antiinflamasi dan antioksidan. Penelitian ini bertujuan untuk mengetahui efek pemberian gel ekstrak biji kopi robusta terhadap jumlah sel makrofag dan limfosit pada gingiva model tikus periodontitis. Jenis penelitian yang digunakan adalah the post test only control group design. Dua puluh ekor tikus dibagi menjadi 5 kelompok yakni kelompok normal, periodontitis, periodontitis yang diterapi gel aloclair, kelompok periodontitis yang diterapi 0,025 g/mL gel ekstrak biji kopi robusta, dan kelompok periodontitis yang diterapi 0,05 g/mL gel ekstrak biji kopi robusta selama 7 hari perlakuan. Tikus didekapitasi dan dilakukan pengecatan HE untuk melihat jumlah sel makrofag dan limfosit. Hasil menunjukkan pemberian gel ekstrak kopi robusta dapat menurunkan jumlah sel makrofag dan limfosit sama dengan aloclair pada model tikus periodontitis yang diinduksi P. gingivalis. Gel ekstrak biji kopi 0,05 g/mL lebih efektif menurunkan limfosit dibandingkan 0,025 g/mL.

Improving oral and dental health through counseling to elementary school students in Jember Ermawati, Tantin; Yani , Ristya Widi Endah; Syafriadi, Mei
Journal of Community Service and Empowerment Vol. 2 No. 1 (2021): April
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/jcse.v2i1.16034

Measures to prevent dental and oral diseases in children can be done by providing information about parts of the teeth, dental caries and the process of dental caries, as well as plaque control as an effort to prevent the occurrence of dental and oral diseases. This activity was carried out aimed at increasing understanding and knowledge of the importance of maintaining oral health in children, especially elementary school students. The knowledge that has been given is expected to be able to change the behavior of students of SDN Kranjingan III Jember, East Java-Indonesia to be able to maintain the health of their teeth and mouth properly. This can be seen through the debris index. In addition to counseling activities, other methods provided were demonstrations of how to brush teeth, demonstration of pictures and posters carried out by the service team from the Faculty of Dentistry, University of Jember. The service activities carried out can increase knowledge and improve the degree of dental and oral health of SDN Kranjingan III Jember students.

Efek Gel Ekstrak Biji Kopi Robusta (Coffea canephora) terhadap Jumlah Sel Makrofag dan Limfosit Jaringan Gingiva Tikus Periodontitis Ermawati, Tantin; Prasetya, Rendra Chriestedy; Fatimatuzzahro, Nadie; Nurul Iffah, Astrid Ganadya
Insisiva Dental Journal: Majalah Kedokteran Gigi Insisiva Vol 9, No 2 (2020): November
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/di.9217

Periodontitis adalah inflamasi kronis yang disebabkan infeksi bakteri salah satunya P. gingivalis. Produk bakteri berupa lipopolisakarida (LPS) mampu meningkatkan sekresi sitokin proinflamatori sehingga terjadi peningkatan jumlah sel makrofag dan limfosit. Hal ini menyebabkan kerusakan jaringan periodontal yang lebih lanjut. Biji kopi robusta memiliki kandungan polifenol, alkaloid dan saponin yang berfungsi sebagai antiinflamasi dan antioksidan. Penelitian ini bertujuan untuk mengetahui efek pemberian gel ekstrak biji kopi robusta terhadap jumlah sel makrofag dan limfosit pada gingiva model tikus periodontitis. Jenis penelitian yang digunakan adalah the post test only control group design. Dua puluh ekor tikus dibagi menjadi 5 kelompok yakni kelompok normal, periodontitis, periodontitis yang diterapi gel aloclair, kelompok periodontitis yang diterapi 0,025 g/mL gel ekstrak biji kopi robusta, dan kelompok periodontitis yang diterapi 0,05 g/mL gel ekstrak biji kopi robusta selama 7 hari perlakuan. Tikus didekapitasi dan dilakukan pengecatan HE untuk melihat jumlah sel makrofag dan limfosit. Hasil menunjukkan pemberian gel ekstrak kopi robusta dapat menurunkan jumlah sel makrofag dan limfosit sama dengan aloclair pada model tikus periodontitis yang diinduksi P. gingivalis. Gel ekstrak biji kopi 0,05 g/mL lebih efektif menurunkan limfosit dibandingkan 0,025 g/mL.

Efek pemberian seduhan kopi robusta (Coffea canephora) terhadap jumlah sel makrofag dan limfosit pada model tikus periodontitis kronisThe effect of brewed robusta coffee (Coffea canephora) on macrophage and lymphocyte cells in rat model of chronic periodontitis Rendra Chriestedy Prasetya; Depi Praharani; Nadie Fatimatuzzahro; Tantin Ermawati; Favinas Octa Nuri Tsalats
Padjadjaran Journal of Dental Researchers and Students Vol 5, No 1 (2021): April 2021
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v5i1.28591

Pendahuluan: Periodontitis merupakan penyakit peradangan yang terjadi pada jaringan pendukung gigi dengan prevalensi tertinggi. Porphyromonas gingivalis merupakan bakteri utama penyebab periodontitis. Pada proses inflamasi terjadi infiltrasi sel mononuklear, yaitu makrofag dan limfosit. Makrofag dan limfosit adalah sel yang berperan penting dalam pertahanan tubuh terhadap patogen selama inflamasi, tetapi apabila makrofag dan limfosit teraktivasi secara berlebihan justru dapat menyebabkan kerusakan jaringan. Salah satu bahan alami yang dapat bertindak sebagai anti-inflamasi adalah kopi Robusta. Penelitian ini bertujuan untuk menganalisis pengaruh seduhan kopi Robusta terhadap jumlah sel makrofag dan limfosit pada tikus model periodontitis. Metode: Jenis penelitian eksperimen laboratorium, menggunakan 20 ekor tikus yang dibagi menjadi 5 kelompok secara acak yaitu kelompok kontrol (K); kelompok tikus yang diinduksi Porphyromonas gingivalis (P5-A); kelompok tikus yang diinduksi Porphyromonas gingivalis dan diberi seduhan kopi robusta (P5-B) dieutanasia pada hari ke-19; kelompok tikus yang diinduksi Porphyromonas gingivalis (P7-A); kelompok tikus yang diinduksi Porphyromonas gingivalis dan diberi seduhan kopi robusta (P7-B) dieutanasia pada hari ke-21. Seduhan kopi robusta yang diberikan sebanyak 3,6 ml selama 14 hari. Pemrosesan jaringan dan pewarnaan HE dilakukan pada preparat rahang bawah. Penghitungan makrofag dan limfosit pada area sekitar tulang alveolar bukal M1 bawah, kemudian dilakukan analisis statistik one-way ANOVA. Hasil: Terdapat perbedaan yang signifikan jumlah sel makrofag dan limfosit antara kelompok kontrol dibandingkan kelompok perlakuan (p<0,05); tidak terdapat perbedaan yang siginifikan (p>0,05) jumlah sel limfosit diantara kelompok perlakuan (P5-A,P5-B,P7-A dan P7-B). Simpulan: Seduhan kopi robusta dapat mengurangi jumlah sel makrofag dan limfosit pada model tikus periodontitis.Kata kunci: Seduhan kopi robusta, makrofag, limfosit, periodontitis. ABSTRACTIntroduction: Periodontitis is an inflammatory disease that occurs in tooth-supporting tissues with a high prevalence. Porphyromonas gingivalis is the primary bacteria that cause periodontitis. In the inflammatory process, mononuclear cell, such as macrophages and lymphocytes, infiltrate. Macrophages and lymphocytes play an essential role in the body’s defence against pathogens during inflammation. However, excessively activated macrophages and lymphocytes can cause tissue damage. One of the natural ingredients that can act as an anti-inflammatory is Robusta coffee. This study was aimed to analyse the effect of brewed Robusta coffee on the number of macrophage and lymphocyte cells in the chronic periodontitis rat model. Methods: This research was a laboratory experiment towards 20 rats, which were randomly divided into five groups: the control group (K); group of mice induced by Porphyromonas gingivalis (P5-A); group of mice induced by Porphyromonas gingivalis and administered with brewed robusta coffee (P5-B), euthanised on the 19th day 19; group of mice induced by Porphyromonas gingivalis (P7-A); group of mice induced by Porphyromonas gingivalis and administered with brewed robusta coffee (P7-B), euthanised on the 21st day. Brewed robusta coffee was administered for as much as 3.6 ml during 14 days. Tissue processing and HE staining were performed on the mandibular preparations—calculation of macrophages and lymphocytes in the area around the lower M1 buccal alveolar. The results were then analysed with one-way ANOVA. Results: There was a significant difference in the number of macrophages and lymphocytes between the control and the treatment group (p<0.05). However, there was no significant difference (p>0.05) found in the number of lymphocytes between all treatment groups (P5-A, P5-B, P7-A, and P7-B). Conclusion: Brewed Robusta coffee can reduce the number of macrophage and lymphocyte cells in the chronic periodontitis rat model.Keywords: Brewed Robusta coffee, macrophage, lymphocyte, periodontitis.

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