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All Journal Jurnal Ilmu Dasar Matematika dan Sains PENA SAINS Vidya Karya Unesa Journal of Chemistry
Leny Yuanita
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Education Energy Materials Science & Nanotechnology Mathematics Physics

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The PENGARUH WAKTU PANEN TERHADAP KADAR FLAVONOID TOTAL DAN AKTIVITAS ANTI-INFLAMASI EKSTRAK ETANOL DAUN YAKON (Smallanthus sonchifolius) Uci Nur Rohmah; Leny Yuanita
Unesa Journal of Chemistry Vol 11 No 2 (2022)
Publisher : Department of Chemistry, Faculty of Mathematics and Natural Sciences, Surabaya State University, located at Jl Ketintang, Surabaya, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (783.38 KB) | DOI: 10.26740/ujc.v11n2.p136-142

Abstract

Yacon (Smallanthus sonchifolius) contains active ingredients in the form of flavonoids. The active ingredients of flavonoids have pharmacological activities such as antimicrobial, anti-inflammatory, and antioxidant. The formation of flavonoids in yacon leaves is influenced by the time of harvest. The study was conducted to determine the effect of harvest time on total flavonoid content and anti-inflammatory activity of ethanol extract of yacon leaf at 4, 6, and 8 months harvest time variations. Yacon leaf extraction process using maceration method. Determination of total flavonoid content in ethanol extract of yacon leaf using a colorimetric method, while testing anti-inflammatory activity using protein denaturation inhibition method. The results showed that harvest time affected total flavonoid content and the anti-inflammatory activity of ethanol extract of yacon leaf. The highest total flavonoid content was obtained at 8 months of harvest, which was 5,366 QE/g. The anti-inflammatory activity of ethanol extract of yacon leaf showed positive results, with an average inhibition value of more than 20% for each harvest time. The best IC50 value is found in yacon leaf with a harvest age of 8 months, which is 29,829 ppm. Keywords: harvest time, flavonoids, anti-inflammatory, yacon leaf
Co-Authors Alif Wildan Mohammad Binar Kurnia Prahani Eka Yulia Maulidah Farid Abdur Rohman Kelvin Rio K Limatahu, Iqbal Mohamad Nur Mohammad Nur MUSLIMIN IBRAHIM Rosalina Eka Permatasari Sunyono - - Suyidno Suyidno Suyono . Suzana Surodjo TITIN SUNARTI Uci Nur Rohmah Wiwik Yuliastuti