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Rilyn Novita Maramis
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Analisis Fitokimia Dan Uji Potensi Ekstrak Etanol Kulit Batang Matoa (Pometia pinnata L) Sebagai Antibakteri Terhadap Pertumbuhan Escherichia coli Djois Sugiaty Rintjap; Elvie Rifke Rindengan; Selfie Petronella Joice Ulaen; Evelina Maria Nahor; Rilyn Novita Maramis
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1717

Abstract

Background: Diarrhea is a health condition, can be caused by Escherichia coli bacteria. Matoa bark has pharmacological activity, can be used as an alternative antibacterial treatment from natural ingredients. Objective: to determine the content of phytochemical compounds and the potential of ethanol extract of matoa bark as an antibacterial against the growth of Escherichia coli. Method: Type of laboratory experiment research, maceration method extraction, 95% ethanol, test solution concentrations of 10%, 20%, 30%. positive control Ciprofloxacin, negative control aquadestilata. Phytochemical analysis based on color reactions and sediment. Antibacterial potential test disc diffusion method, inhibition zone measured using calipers, observation 1x24 hours. Results: Ethanol extract of matoa bark contains phytochemical compounds flavonoids, triterpenoids, saponins, tannins. The extract concentrations of 10%, 20%, and 30% have antibacterial activity with an average inhibition zone diameter of 15.75±0.39 mm, 16.09±0.19 mm, and 18.14±0.73 mm, respectively, which are classified as strong. The diameter of the inhibition zone for Ciprofloxacin is 29.56±0.30 mm. The higher the concentration of the extract, the larger the inhibition zone. Conclusion: The ethanol extract of matoa (Pometia pinnata L) stem bark contains phytochemical compounds flavonoids, triterpenoids, saponins, and tannins. Concentrations of 10%, 20%, and 30% have antibacterial activity against Escherichia coli, which are classified as strong. The best test results were obtained at a concentration of 30%.
Co-Authors Djois Sugiaty Rintjap Djois Sugiaty Rintjap Dumanauw, Jovie Mien ELVIE RIFKE RINDENGAN, ELVIE RIFKE Evelina Maria Nahor Gurning, Sri Handayani Juliet Tangka Kalonio, Donald Emilio Kusbandia Lauree Talya Devaluna Salainti Nahor, Evelina Maria Paputungan, Marcelia Selfie Petronella Joice Ulaen Soenjono, Steven Jacob Suleman, Nurningsih Ulaen, Selfie Petronela Joice Yos Banne