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All Journal ad-Dawaa : Journal of Pharmaceutical Sciences Parapemikir Jurnal Ilmiah Farmasi Jurnal Sains dan Kesehatan
Nurshalati Tahar
UIN Alauddin Makassar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics

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Formulation and Antibacterial Activity of Porang (Amorphophallus muelleri Blume) Extract Gel Against Propionibacterium acne Nurshalati Tahar; Dwi Wahyuni; Rabiatul Adawiyah; Khaerani; Munifah Wahyuddin
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 6 No. 1 (2023)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v6i1.38744

Abstract

Introduction: The increase in bacterial resistance to antibiotics provides an opportunity to obtain antibacterial compounds from natural ingredients. Porang is a plant belonging to the Araceae family that has potential against Propionibacterium acne. Aims: This study aims to determine the effectiveness of the preparation of porang tuber extract gel against Propionibacterium acne. Methods: The porang were extraction by maceration using ethanol. The extract porang were made gel with various concentration and evaluation their stability and antibacterial activity using disc diffusion method. Result: The hedonic test showed no significant differenece each of formula and stable during storage in two weeks. On the other hand, only formula F2 and F3 can inhibit of Propionibacterium acnee. Conclusion: The porang extract can made of gel and good stability. The formula F2 and F3 have antibacterial activity.
UJI TOKSISITAS FRAKSI DAUN PEDADA (SONNERATIA CASEOLARIS L.) TEHADAP LARVA UDANG (ARTEMIA SALINA LEACH) DENGAN MENGGUNAKAN METODE BRINE SHRIMP LETHALITY TEST (BSLT) Muh Fitrah; Nurshalati Tahar; Husniar Husniar
Parapemikir : Jurnal Ilmiah Farmasi Vol 7, No 1 (2018): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v7i1.739

Abstract

Telah dilakukan penelitian tentang Uji Toksisitas Fraksi Daun Pedada (Sonneratia caseolaris L.)Terhadap Larva Udang (Artemia Salina Leach) Dengan Menggunakan Metode Brine Shrimp LethalityTest (BSLT).Penelitian ini bertujuan untuk mengetahui efek toksisitas dan identifikasi golongan senyawadari fraksi aktifDaun Pedada (Sonneratia caseolaris L.) dengan metode Brine ShrimpLethality Testterhadap Artemia salina Leach. Penelitian diawali dengan pengambilan sampel, pengeringan sampel danekstraksi dengan maserasi bertingkat menggunakan pelarut n-heksan, etil asetat, etanol dan air. Ekstrakkemudian dipekatkan dengan Rotary evaporator. Ekstrak yang diperoleh selanjutnyadiuji toksisitasnyadan diperoleh hasil ekstrak etanol memiliki tingkat toksik yang lebih besar dibandingkan ekstrak lainnyadengan nilai LC50 sebesar 28.18 μg/ml. Ekstrakkemudian difraksinasi dengan kromatografikolomsehingga diperoleh 12 fraksi.Masing-masing fraksi diuji toksisitasnya dan diperoleh hasil fraksi F11 yangmemilikitingkat toksik yang lebih besar di bandingkan fraksi lainnya dengan nilai LC50 sebesar 46.77μg/ml. Hasil identifikasi fraksi F11 menunjukkan adanya golongan senyawasteroid, flavanoid danfenolik.Kata kunci : Brine Shrimp Letality Test (BSLT), Daun Pedada (Sonneratia caseolaris L.), Flavanoid,Steroid, dan Fenolik
Analisis Kualitatif dan Kuantitatif Antioksidan Parang Romang: Qualitative and Quantitative Antioxidant Analysis of Parang Romang Muhammad Ikhlas Arsul; Nurshalati Tahar; Afrisusnawati Rauf
Jurnal Sains dan Kesehatan Vol. 4 No. 4 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i4.1230

Abstract

Antioxidants can be found naturally in plants, animals, and microbes, or they can be produced chemically. The selection of plants to find the new bioactive compounds are carried out through ethnobotany and chemotaxonomic approaches. One plant that can be developed as an antioxidant is parang romang (Boehmeria virgata). This study aimed to identify an antioxidant activity on the roots, stems, leaves, and flowers of parang romang plant qualitatively and quantitatively. The parang romang plant used was obtained from Malino Regency, South Sulawesi. The roots, stems, leaves, and flowers were extracted using the reflux method and then concentrated using a rotary evaporator. Each part was analyzed for its chemical content and activity qualitatively and quantitatively. Qualitative analysis was carried out with sitroborat, folin ciocalteu, DPPH, FRAP, and CUPRAC reagen, while quantitative analysis was carried out by spectrophotometry using the DPPH method. The roots, stems, leaves, and flowers were detected to contain phenolic, and flavonoid compounds and have antioxidant activity based on qualitative analysis. The antioxidant activity of parts of the parang romang plant is classified as strong to very strong, with an AAI value of 1.5 - 4.54. All parts of the plant tested have antioxidant activity.  
Co-Authors Afrisusnawati Rauf Dwi Wahyuni Husniar Husniar Khaerani Muh Fitrah Muhammad Ikhlas Arsul Munifah Wahyuddin Rabiatul Adawiyah