Khanisyah Erza Gumilar
Department Of Obstetrics & Gynecology, Faculty Of Medicine, Airlangga University, Dr. Soetomo Hospital, Surabaya

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Maternal and Perinatal Outcomes in Uncorrected Tetralogy of Fallot Khanisyah Erza Gumilar; Christina Meilani Susanto; Erry Gumilar Dachlan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15023

Abstract

Background: Tetralogy of Fallot (TOF) is the most common congenital heart disease in the population.Correction of TOF during infancy or childhood may increase the quality of patient’s life. Uncorrected TOFmay cause further complications later on. Pregnancy with uncorrected TOF may cause complications onboth maternal and fetal sides.Objective: to analyze maternal and perinatal outcomes in patients with uncorrected TOF during pregnancy.Methods: This is a retrospective study. A total of 8 pregnant women diagnosed with TOF registered inthe Obstetric-Cardiac unit in 3 years (2016-2018). Medical records were reviewed for clinical assessment,echocardiography results, and therapy during hospitalization. Patients were contacted by telephone to providean obstetric history, including details of pregnancy and delivery. Five of 7 patients able to be contacted, andhome visits were done to evaluate their conditions.Results: There were 8 pregnant women with uncorrected TOF. Most cases (87,5%) were first diagnosedduring pregnancy and delivery. Intra-Uterine Growth Restriction (IUGR) and abortion (62.5% and 25%,respectively) were the most obstetric complications. Cardiac complications were cardiogenic shock (12.5%),thromboembolic (12.5%), and various degree of heart failure (62.5%). The number of Small for GestationalAge (SGA) was 66.7%. Incidence of congenital heart disease (CHD) in the fetus was 20%. One death caseand 2 abortions from a total of 8 cases were found.Conclusion: TOF may cause many maternal and fetal complications. The most common maternalcomplications are heart failure, cardiogenic shock and thromboembolic, while perinatal complicationsinclude IUGR, SGA and abortion.
Characteristics of Peripartum Cardiomyopathy (PPCM) pregnancy and preeclampsia in Dr Soetomo Hospital, Surabaya, Indonesia, 2014-2016 Dibya Arfianda; Budi Wicaksono; Khanisyah Erza Gumilar; Andrianto Andrianto
Majalah Obstetri dan Ginekologi Vol. 27 No. 1 (2019): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (334.898 KB) | DOI: 10.20473/mog.V27I12019.40-44

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Objectives: to present data on the characteristics of pregnancy with PPCM and PE. Management of patients with PPCM is almost the same as for patients with acute or chronic heart failure, which uses drug therapy. PPCM and preeclampsia (PE) are two related diseases, although not directly. Both have similar pathophysiological mechanisms.Case Report: We present 25 pregnancy cases with PPCM at Dr. Soetomo Hospital within 3 years. Data were collected from January 2014 to December 2016, consisting of 5 PPCM cases and the other 20 cases were PPCM with PE cases.Conclusion: Pregnancy with PPCM-PE has higher morbidity than PPCM only. The diagnosis of PPCM should be established immediately if heart failure symptoms are found in the third trimester and the patient has risk factors, such as age >30 years, multigravida, obesity, and multiple pregnancy.
Peripartum cardiomyopathy and its relationship with preeclampsia Christina Meilani Susanto; Khanisyah Erza Gumilar
Majalah Obstetri dan Ginekologi Vol. 28 No. 2 (2020): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V28I22020.52-58

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Objectives: To know the characteristic of PPCM in RSUD Dr. Soetomo Hospital Surabaya and to know the relationship between PPCM and PE.Materials and Methods: This was a case control study. Data was obtained from medical record of 2843 patients within 2014-2015, divided into 2 groups, 19 patients with PPCM in a case group, and 2824 patients in control group. The statistical analysis used was Fisher exact test.Results: Peripartum cardiomyopathy patients were older compared to control group (32.21 ± 6.83 y.o vs 29.26 ± 6.45 y.o). The incidence of PPCM in our study was about 1 per 149 live births. Most cases were diagnosed antepartum (52.63%), and about 84.2% PPCM cases were also complicating with preeclampsia. The statistical analysis revealed that there was increase risk of PPCM if the pregnant women complicates PE during pregnancy, with Odds Ratio (OR) 20.679, p<0.05. The most common perinatal outcomes was Small for Gestational Age (SGA) babies (81.8%), whereas case fatality rate (CFR) in maternal was 15.7%.Conclusion: Although diagnosis of PPCM is still an exclusion diagnosis, we have to pay more attention to pregnant women complicating with preeclampsia, since preeclampsia can increase the risk of PPCM.
Maternal Deaths caused by COVID-19 Infection in the First Year of the Pandemic Wave Muhammad Ilham Aldika Akbar; Pungky Mulawardhana; Manggala Pasca Wardhana; Khanisyah Erza Gumilar; Ecccita Raheestyningtyas; Muhammad Ardian Cahya Laksana; Jimmy Yanuar Anas; Ernawati; Hermanto Tri Joewono; Muhammad Adrianes Bachnas; Brahmana Askandar Tjokroprawiro
Folia Medica Indonesiana Vol. 59 No. 2 (2023): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/fmi.v59i2.45226

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Highlights: These cases of maternal deaths caused by COVID-19 infections illustrated the significant risk factors for maternal mortality during the early phases of the pandemic, while studies had not extensively reported this. COVID-19 infections increase the risk of maternal and neonatal mortality, with infants having a lower chance of survival even if they are delivered. Respiratory support, antiviral medications, antibiotics, anticoagulants, and supportive care are the primary treatments for severe COVID-19 in pregnancy. AbstractThis article presents seven cases of maternal deaths attributed to COVID-19 during the first year of the pandemic wave. These cases provide insights into the natural progression of COVID-19 in pregnant women who were not vaccinated. This study showed that COVID-19 significantly increased maternal and neonatal mortality and morbidity. All of the patients exhibited symptoms of fever, cough, and dyspnea upon admission to the hospital. They were admitted with elevated respiratory rates (26–32 times/minute) and low oxygen saturation (<95%). Four patients had obesity, while one patient had pregestational diabetes. The COVID-19 diagnosis was established using a rapid antibody or antigen test and chest X-ray, which indicated pneumonia. Medical interventions administered to the patients included antiviral therapy (5 patients), antibiotics (6 patients), and anticoagulants (4 patients). From a total of five babies delivered, four babies were delivered via cesarean section. Two babies were not delivered due to previability and maternal deaths before delivery. The patients passed away within 3–10 days of hospital admission. In conclusion, adequate and early intervention and management of pregnant women infected with COVID-19 are crucial in preventing maternal and neonatal deaths, especially in unvaccinated women. 
Simultaneous Myomectomy and Cesarean Section: A Dual Surgical Approach Pregnancy with enormous fibroid Baktiar, Muhammad Priza; Abd Rauf, Khairunnisa binti; Gumilar, Khanisyah Erza
Indonesian Journal of Perinatology Vol. 4 No. 2 (2023): Available online : 1 December 2023
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v4i2.35

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Introduction: Myomectomy during cesarean section (CS) is a complex but increasingly common surgical approach used in cases of large uterine fibroids in pregnant patients. This report aims to evaluate the efficacy and safety of myomectomy in conjunction with CS for large uterine myoma. Case description: A retrospective study was conducted on two pregnant patients with large uterine myomas who underwent myomectomy during CS at a Hospital of Universitas Airlangga. Clinical data, myoma characteristics, and maternal and neonatal outcomes were evaluated. Myoma sizes were 15x15cm and 15x20cm, and both were intramural. No significant intraoperative complications occurred. Bleeding during surgery was well controlled, and all patients recovered without adverse events. The duration of surgery was 60 and 70 minutes. Patients were discharged home within 3 days after surgery, and all neonates were born healthy with no congenital abnormalities. Conclusion: Simultaneous myomectomy with CS is a successful and safe method of managing big uterine myomas in pregnant women. This surgery has two advantages: it treats maternal fibroid problems while also ensuring maternal and newborn safety during CS. The installation of a Foley catheter for uterine artery clamping aids in preventing excessive bleeding during surgery. This method can be used to handle pregnant individuals with big uterine myomas who require CS.
Maternal and Neonatal Outcome in Pregnant Women with Obesity in a Single Tertiary Referral Hospital in January - December 2017 Virdayanti, Dian Puspita; Gumilar, Khanisyah Erza
Jurnal Medis Islam Internasional Vol 1 No 2 (2020): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v1i2.1616

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Background: Maternal obesity is defined when BMI is above 30. It is now considered one of the most commonly occurring risk factors seen in obstetric practice and it increased risks of specific complications, and to medical, surgical and technical challenges in providing safe maternity care. Objectives: This study aims to review maternal dan neonatal outcomes and complications from pregnant women with obesity in Soetomo General Hospital on January - December 2017. Methods: Retrospective cross-sectional study by using medical record data of Dr. Soetomo General Hospital on January - December 2017. Results: There were 297 (21,5%) of maternal obesity from 1384 deliveries, in which the majority age range from 20-34 years old and multiparity. The most BMI category was BMI class 1 (61%). Caesarean section (77,4%) in this study became a major proportion in mode of delivery. In our study, the incidence of hypertension in pregnancy was high (45,4%), while the incidence of severe preeclampsia were 20,9%. The incidence of gestational diabetes were 7,1%, and pregestational diabetes were 3,4%. In our cases, there were 294 cases (94,2%) of livebirth, while there were four stillbirth cases. The incidence of intrauterine fetal death were four cases. There were 11 cases of macrosomia, 7 in 11 came from mother with obesity class III. Other neonatal complications are intrauterine growth restriction which were 26 cases and 18 cases congenital malformation. Conclusion: Most maternal complications in obese pregnant women are severe preeclampsia with mode of delivery by cesarean section. Gestational diabetes cases were found mostly in maternal obesity class I, while pregestational diabetes cases were found mostly in maternal obesity class II. Most neonatal Apgar score in our study were between 7-10, while most of congenital malformation was omphalocele
The Pregnancy and Delivery with Cardiac Disease in Dr. Soetomo Hospital 2018 Rahayu, Ana Puji; Gumilar, Khanisyah Erza
Jurnal Medis Islam Internasional Vol 2 No 2 (2021): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v2i2.1822

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Background: Cardiac disease is one of the non obstetric problems causing mortality both in pregnancy and labor due to the complications. Preventions for the complications have not been implemented, thus the number of patients which have cardiac disease with complications and perinatal outcome with low birth weight is still high. Objective : To identify maternal and neonatal outcome of pregnant women with cardiac disease in dr. Soetomo Surabaya hospital in 2018. Method: Descriptive retrospective study using medical records in dr. Soetomo Surabaya hospital 2018. Result: We found 1433 pregnancy cases with 51 (3,6 %) patients were having cardiac disease and included in this research. The most common maternal complication was pulmonary hypertension 16 cases. A dead case was found 1 case (1,9 %) with eissenmenger syndrome. We found the perinatal outcome of 30 babies (58.8%) born with a weight of 2500 gram and under. There are 7 patients with cardiac disease that have been corrected (13,7%). Among those 7 patients, 6 had a perinatal outcome with a birth weight of more than 2500 gram. Conclusion : Most pregnant patients with cardiac disease in dr. Soetomo Surabaya hospital 2018 are already having some complications with perinatal outcomes of low birth weight. Therefore, management of cardiac disease in pregnancy to prevent complications by means of preconception counseling, good antenatal care, and appropriate referrels are still needed to improve the quality of maternal and neonatal outcomes.
The promise and challenges of Artificial Intelligence-Large Language Models (AI-LLMs) in obstetric and gynecology Gumilar, Khanisyah Erza; Tan, Ming
Majalah Obstetri & Ginekologi Vol. 32 No. 2 (2024): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I22024.128-135

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HIGHLIGHTS 1. The article highlights how Artificial Intelligence with Large Language Models (AI-LLMs) greatly improves diagnosis and treatment personalization in obstetrics & gynecology, and also enhances medical education through interactive simulations and up-to-date learning materials.2. The article also discusses the ethical issues linked to AI, emphasizing the need for cooperation among different stakeholders to use AI responsibly in medicine, focusing on protecting data privacy and minimizing reliance on technology.   ABSTRACT The introduction of Artificial Intelligence through Large Language Models (AI-LLM) into medicine holds great promise for improving patient care and medical education, especially in obstetrics and gynecology. AI-LLM can significantly improve diagnostic accuracy and treatment efficiency by utilizing large medical databases, which is especially useful for dealing with rare diseases that are difficult to document or understand by human practitioners alone. In addition, AI-LLM can provide informed patient care recommendations by analyzing large amounts of data and providing insights based on unique patient profiles, with the added benefit of being accessible 24/7 via the internet. This constant availability ensures that patients receive prompt information and assistance as needed. In the field of education, AI-LLMs enhance the learning experience by incorporating interactive simulations into the curriculum, improving medical students' and professionals' practical knowledge. They also ensure that educational materials are always up-to-date reflecting the most recent research and worldwide medical standards. This access latest information from global resources helps to bridge the educational gap, making advanced knowledge more accessible to learners regardless of their geographic location. However, the introduction of AI-LLMs is not without challenges. Ethical issues, such as data privacy and the risk of overreliance on technology, must be addressed. Effective management of these concerns necessitates collaboration among medical professionals, technological experts, academics, hospital committees, and representatives of patients. This multidisciplinary teamwork is vital for upholding ethical norms and preserving patient dignity and respect. AI-LLMs can considerably improve both patient care and medical education in obstetrics and gynecology provided they are appropriately balanced with innovation and ethics.
Neonatal Outcome Associated With Birth Order and Chorionicity in Twin Pregnancy Pratama, Nur Aprilianita; Gumilar, Khanisyah Erza; Bachnaas, Muhammad Adrianes; Aldika Akbar, Muhammad Ilham
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 2 April 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i2.2391

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Objectives: The objective of this study is to examine the neonatal outcomes of twin pregnancies based on the difference of chorionicity and order of delivery. Methods: An observational cross-sectional study was done among all women with >24 completed weeks gestation having twin pregnancies in the Department of Obstetrics and Gynaecology of Dr. Soetomo General Hospital and Universitas Airlangga Hospital, Surabaya, Indonesia in 2023. Results: 49 twin from 1638 birth (2.99%) were recruited for the study. The MC groups had a higher prevalence of preterm birth <37 weeks (83.3 vs 53.8%), preterm birth <34 weeks (52.8 vs 15.4%), VLBW (25 vs 7.7%), ELBW (25 vs 15.4%), low Apgar scores at 5th minutes (50 vs 15.4%), admission to NICU (66.7 vs 15.4%), RDS (41.7 vs 7.7%), early neonatal death (33.3 vs 7.7%), and perinatal death (44.4 vs 15.4%) [p<0.05]. In relation to birth order, there were no significant difference in all neonatal outcomes, except the higher prevalence of lower Apgar scores in 1st (75 vs 50%) and 5th minutes (50 vs 19.4) in the second delivered MC twin (p=0.05). Out of the 98 twin babies, there were a total of 32 perinatal deaths (32.65%), consisting of eight stillbirths and twenty-four neonatal deaths. Conclusions: Chorionicity and birth order were influenced by the neonatal outcomes of twin pregnancies. It is important to manage twin pregnancy in specialized or tertiary care center hospital.