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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Jurnal Kebidanan Althea Medical Journal Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Majalah Obstetri dan Ginekologi Public Health of Indonesia Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Keperawatan Muhammadiyah Amerta Nutrition Care : Jurnal Ilmiah Ilmu Kesehatan Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan NURSING UPDATE JURNAL ILMIAH ILMU KEPERAWATAN Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology Jurnal Abdi Masyarakat Indonesia Asian Journal of Health Research Strada Jurnal Ilmiah Kesehatan (SJIK) JURNAL KEPERAWATAN
Hermanto Tri Joewono
Department Of Obstetrics And Gynecology, Faculty Of Medicine, Airlangga University
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Faktor Risiko Depresi Antenatal Di Puskesmas Jagir Dan Tanah Kali Kedinding Surabaya Hasanah, Zumroh; Joewono, Hermanto Tri; Muhdi, Nalini
Jurnal Keperawatan Muhammadiyah Vol 4, No 2 (2019): JURNAL KEPERAWATAN MUHAMMADIYAH
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (231.383 KB) | DOI: 10.30651/jkm.v4i2.3105

Abstract

Objective: To find out the prevalence and analyze the risk factors (biological, psychological and social) of pregnant women who experience antenatal depression at health center of Jagir and Tanah Kali Kedinding Surabaya.Methods: A cross sectional study design, after got the ethical clearance certificate, the subjects were pregnant women who visited antenatal clinic and meet the criteria in Mei-Juni 2019. Independent variables were biological factors : a history of Premenstrual dysphoric disorder (PMDD), and obstetric status (age, history of miscarriage and mode of delivery, and risk of pregnancy), psychological factors : the history of child abuse and negative life events and social factors : marital conflict, pregnancy status, family/spouse/social support, and financial stress. The dependent variable was determined by Edinburgh Postnatal Depression Scale (EPDS) with a cut off value of 10. Statistics analysis used accordingly.Results: The prevalence of antenatal depression was 18.95%. The statistic calculation found that age (P=0.168),  history of miscarriage and mode of delivery (P=0.540), risk of pregnancy (P=0.756), history of PMDD (P=1.000), history of child abuse (P=0,219), negative life events (P=0.870), marital conflict (P=1,000), pregnancy status (P=1,000), family, spouse and social support (P= -), and financial stress (P=1,000).Conclusion:There was no relationship between antenatal depression and the age of pregnant women, history of miscarriage and mode of delivery, pregnancy risk, history of PMDD, history of child abuse, negative life events, marital conflict, pregnancy status, family, spouse and social support, and financial stress.
Synapsis Expression Increased By Mozart’s Music Stimulation Compared With Indonesian Pop And Religious Music Amila, Ukhti Mukminah ilmi; Joewono, Hermanto Tri; Widjiati, Widjiati
Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol 16, No 1 (2020): June 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.513 KB) | DOI: 10.22219/sm.Vol16.SMUMM1.10784

Abstract

Classical music stimulation is a proven method that affect intelligence as well as brain function. Mozart’s classical music is classical music that could stimulate the growth of synaptic networks. To analyze the difference of synapsin expression of the brain of Rattus norvegicus  offspring on Mozart’s, pop, religious and without music stimulation during pregnancy. Experimental. Treatments were subjected to Rattus norvegicusas a subject organism, initiated on the 10th day of pregnancy, in 1 hour duration in a soundproof chamber, intensity of 65 dB. On the 19th day of pregnancy the subjects were sacrificed and three offsprings were chosen. The head of the chosen Rattus norvegicusoffsprings were decapitated and the brain subsequently sectioned to calculate synapsin expression by immunohistochemistry method with 400 magnification strength microscope on the 5 field of view. Significant difference of synapsin expression of the brain of Rattus norvegicus offspring was observed between Mozart’s and control group. Significant differences of synapsin expressions were observed in the cerebellum of the newly born Rattus novergicus between Mozart and pop music groups (p = 0,007), Mozart and religious music groups (p = 0,008), Mozart and without music groups (p = 0,004).Synapsin expression of Rattus norvegicus brain offsprings were higher in Mozart music stimulation compared with pop and religious music stimulation
PERBEDAAN PENGARUH PAPARAN MUSIK MOZART, BEETHOVEN, DAN CHOPIN SELAMA KEBUNTINGAN TERHADAP KEPADATAN DENDRIT DI CEREBELLUM RATTUS NORVEGICUS BARU LAHIR Amishinta, Ancha Ayu; Joewono, Hermanto Tri; Widjiati, DR
NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 10 No 1 (2019): MARET
Publisher : NHM PRESS

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Abstract

Indonesia is categorized as middle humandevelopment index. One of the causes is the fluentignorance of brain growth and development during1000 days of life period. This period is the bestopportunity to give proper stimulations to increase themaximal brain growth and development. Exposure toclassical music such as Mozart, Beethoven, andChopin music can increase the wave of brain activity.During pregnancy, Mozart music is proven to increasethe dendritic density. Analyzing the difference ofdendritic density of cerebrum and cerebellum ofnewborn baby of Rattus norvegicus that are exposedto the Mozart, Beethoven, and Chopin music, and thatis not exposed to music during pregnancy. Laboratoryexperimental research, posttest-only control groupdesign. Subjects were female pregnant Rattusnorvegicus, grouped into 4 random groups: 1 controlgroup and 3 treatments groups; with 6 samples each.Subjects were super ovulated, and 65 dB intensity ofmusic was played for an hour at 20.00-21.00 on thesubjects on 10th day of pregnancy. On 20th day ofpregnancy, the mothers were dissected usingcaesarean section. 2 heaviest newborn babies ofRattus norvegicus were taken, and their brain tissueswere taken as samples. The dendritic density ofcerebrum and cerebellum were observed using GolgiCox method of silver impregnationprocedure.Statistical test concluded there weresignificant differences of dendritic density of cerebrumand cerebellum of newborn babies of Rattusnorvegicus among the exposure to Mozart,Beethoven, and Chopin music, and without theexposure to music with value of p=0,004 (<0,05) incerebrum and p=0,003 (<0,05) in cerebellum. Thedendritic density of cerebrum and cerebellum ofnewborn babies of Rattus norvegicus that wereexposed to Mozart music during pregnancy werehigher than that are exposed to Beethoven andChopin music and that were not exposed to music. Itis recommended for the next research to do furtherresearch to prove the dendritic density caused by themusical stimulation during pregnancy when Rattusnorvegicus grows up
PERBEDAAN PENGARUH PAPARAN MUSIK MOZART, BEETHOVEN, DAN CHOPIN SELAMA KEBUNTINGAN TERHADAP INDEKS APOPTOSIS SEL NEURON DI CEREBELLUM RATTUS NORVEGICUS BARU LAHIR Fajrin, Dessy Hidayati; Joewono, Hermanto Tri; Widjiati, DR
NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 10 No 1 (2019): MARET
Publisher : NHM PRESS

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Abstract

The efforts that can be done to improvebrain cells in the prenatal period is the provision ofnutrients and good stimulation. Exposure to classicalmusic such as Mozart, Beethoven, and Chopinmusic can increase the wave of brain activity. Duringpregnancy, Mozart music is proven to decrease theapoptosis of neuronal.Analyzing the difference of apoptosisneuronal of cerebrum and cerebellum of newbornbaby of Rattus norvegicus that are exposed to theMozart, Beethoven, and Chopin music, and that isnot exposed to music during pregnancy.Laboratory experimental research, posttestonly control group design. Subjects were femalepregnant Rattus norvegicus, grouped into 4 randomgroups: 1 control group and 3 treatments groups;with 6 samples each. Subjects were super ovulated,and 65 dB intensity of music is played for an hour at20.00-21.00 on the subjects on 10th day ofpregnancy. On 20th day of pregnancy, the motherswas dissected using SC technique. 2 heaviestnewborn babies of Rattus norvegicus were taken.Statistical test concluded there wassignificant differences of apoptosis neuronal ofcerebellum of newborn babies of Rattus norvegicusamong the exposure to Mozart, Beethoven, andChopin music, and without the exposure to musicwith value of p=0,033 in cerebellum.In conclution, the exposure of Mozart?smusic during pregnancy perform expression ofBDNF cerebellum in the offspring-rat was higherthan exposed Beethoven?s music, Chopin and notexposed to music.
Combined Effect of Physical and Psychological Stress Exposure during Pregnancy on the Expression of Caspase-3 Cerebrum and Cerebellum of Newborn Mus musculus Binta Dwi Novitasari; Hermanto Tri Joewono; Widjiati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16751

Abstract

Background: Prenatal stress affects fetal development including brain development. When a stressor isfelt, the brain as the main target for stress will release a hormone that stimulates the release of pro-apoptoticproteins and activate caspase-3 which acts as an executioner caspase in the cell death process. The aim of thestudy was to analyze the effect of combined stress during pregnancy on the expression of caspase-3 cerebrumand cerebellum of newborn Mus musculus. Methods: An experimental study using 24 pregnant mice (Musmusculus). Subjects were randomized into four groups, consisting of physical stress exposure group (forcedswimming) (G1), psychological stress exposure group (noise) (G2), combination stress exposure group(forced swimming + noise) (G3), and control group (G4). Stress exposure was given on 6th-15th days ofpregnancy. From each mother, three Newborn of Mus musculus were taken to make preparations from braintissue. Immunohistochemical examination was performed to assess caspase-3 expression. Results: Thestudy shows that the mean and standard deviation of the expression of caspase-3 cerebrum and cerebellumin the physical stress exposure group is 5.70 ± 0.99 and 5.80 ± 1.35, the psychological stress exposure groupis 7.23 ± 1.39 and 7.40 ± 1.24, the combined stress exposure group is 8.67 ± 1.09 and 9.30 ± 1.12, and thecontrol group 4.17 ± 1.18 and 3.90 ± 1.06. ANOVAs statistical test results show significant differencesamong groups with a value of p = 0.000 in the cerebrum and p = 0.000 in the cerebellum. Conclusion:Exposure to physical and psychological stress during pregnancy increases the expression of caspase-3 in thecerebrum and cerebellum of newborn mice.
Effect of Murotal Sound Stimulation during Pregnancy on the Number of Neuron Cells of Cerebrum and Cerebellum of the Newborn Rattus norvegicus Ayu Putri Yani; Hermanto Tri Joewono; Widjiati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16809

Abstract

Background: The human development index (HDI) illustrates how superior human resources are. Thestimulation of Murotal during growth and development has been shown to increase cell growth in plants.The aim of the study was to analyze the effect of the differences againts the number of neuron cell’s in thecerebrum and cerebellum Rattus norvegicus offspring between those who received Al-quran Murottal surahAr-Rahman stimulation, Qori and Qoriah sounds voice in pregnancy day of 6th. Methods: An Experimentalstudy using 30 pregnant (Rattus norvegicus). Subjects were randomized into three groups, control group(Q1), voice of Qori group (Q2), and voice of Qoriah group (Q3). sound stimulation was given on 6th-17thdays of pregnancy. From each mother, two Newborn of Rattus norvegicus were taken to make preparationsfrom brain tissue. Eosin Hematocycline was performed to assess number of neuron cells. Results : Thestudy shows that the mean and standard deviation of the number neuron cells cerebrum and cerebellum inthe control group is 9.88 ± 1.71 and 21.10 ± 2.11, the voice qori group is 10.16 ± 1.01 and 22.46 ± 1.71,and the voice qoriah group 11.12 ± 1.52 and 22.50 ± 1.76. ANOVAs statistical test results show there isno significant differences among groups with a value of p = 0.152 in the cerebrum and p=0.183 in thecerebellum. Conclusion : Murotal sound stimulation during pregnancy increased the number of neuron cellsin the cerebrum and cerebellum of newborn rats.
Combined Effect of Physical and Psychological Stress Exposure during Pregnancy on the Expression of Caspase-3 Cerebrum and Cerebellum of Newborn Mus Musculus Binta Dwi Novitasari; Hermanto Tri Joewono; Widjiati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16817

Abstract

Background: Prenatal stress affects fetal development including brain development. When a stressor isfelt, the brain as the main target for stress will release a hormone that stimulates the release of pro-apoptoticproteins and activate caspase-3 which acts as an executioner caspase in the cell death process. The aim of thestudy was to analyze the effect of combined stress during pregnancy on the expression of caspase-3 cerebrumand cerebellum of newborn Mus musculus. Methods: An experimental study using 24 pregnant mice (Musmusculus). Subjects were randomized into four groups, consisting of physical stress exposure group (forcedswimming) (G1), psychological stress exposure group (noise) (G2), combination stress exposure group(forced swimming + noise) (G3), and control group (G4). Stress exposure was given on 6th-15th days ofpregnancy. From each mother, three Newborn of Mus musculus were taken to make preparations from braintissue. Immunohistochemical examination was performed to assess caspase-3 expression. Results: Thestudy shows that the mean and standard deviation of the expression of caspase-3 cerebrum and cerebellumin the physical stress exposure group is 5.70 ± 0.99 and 5.80 ± 1.35, the psychological stress exposure groupis 7.23 ± 1.39 and 7.40 ± 1.24, the combined stress exposure group is 8.67 ± 1.09 and 9.30 ± 1.12, and thecontrol group 4.17 ± 1.18 and 3.90 ± 1.06. ANOVAs statistical test results show significant differencesamong groups with a value of p = 0.000 in the cerebrum and p = 0.000 in the cerebellum. Conclusion:Exposure to physical and psychological stress during pregnancy increases the expression of caspase-3 in thecerebrum and cerebellum of newborn mice.
The Effect of Exposure Qari and Qariah Recitation During Pregnancy to the Number of Astrocyte Glia Cells in the Cerebrum Newborn Rattus Norvegicus Dwi Nurdi Puspita Sari; Widjiati; Hermanto Tri Joewono
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16840

Abstract

The quality of human resources should be prepared since in early stage. Pregnancy is one of a significantperiod which can take advantage to by providing proper nutrition and adequate stimulation. For instance,sound and music, the most harmonious combination and easily accepted by the fetus(1). Experimentalanalytic type with post-test only control group design was employed on 30 pregnant Rattus norvegicus whichwere divided randomly into 3 groups, namely the control group, qari group, and qariah group. Each of thegroups had stimulation starting 6th to 17th days of pregnancy for 60 minutes. At 18 days of pregnancy, themother of Rattus Norvegicus was sacrificed and bring forth with Sectio Caesarea (SC). As a result, thenumber of astrocyte glia cells in the cerebrum was higher in the qaria recitation stimulation group (22.62 ±3.75), compared with the group that was listened to qari recitation stimulation group (19.84 ± 2.48), whilethe control group (16.54 ± 2.78). A significant difference found in the number of astrocyte glia cells inthe Cerebrum Rattus norvegiccus newborn that were listened to the qari and qariah recitation stimulationgroup and the control group. The highest number of Glia cells is obtained from the stimulation of qariahrecitation.
Qari (Male Voice) Increases Higher Expression of Synapsin 1 than Qariah (Female Voice) in the Cerebrum Newborn Rattus Norvegicus Nur Laila Faizah; Hermanto Tri Joewono; Widjiati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17002

Abstract

Introduction: Pregnancy is the golden period to prepare children for the future. Stimulation is neededduring pregnancy, one of which is brain stimulation. This can be done with Al Qur’an Murrotal SurahAr-Rahman stimulation. This study aims to analyze expression of synapsin 1 in the cerebrum of newbornRattus norvegicus when given murrotal Surah Ar-Rahman stimulation by qari, qariah, and not given anystimulation during pregnancy.Methods: Experimental with post-test only control group design. Sampling in this study was consideredhomogeneous because it met the inclusion criteria. The samples obtained were distributed randomly to eachexperimental group and randomized into 3 groups, including control group, group stimulated by qari, andgroup stimulated by qariah. The treatment was given on the 6th day of pregnancy for 1 hour in a soundproofroom with an intensity of 65 dB.Results: The highest mean expression of synapsin 1 in the cerebrum is qari group (6.96 ± 2.59), then qariahgroup (5.84 ± 2.90), and the lowest is control group (5.74 ± 2.32). There is no significant difference inexpression of synapsin 1 in the cerebrum between control and qari groups (p = 0.306), control and qariahgroups (p = 0.932), qari and qariah groups (p = 0.347).Conclusion: The highest expression of Synapsin 1 in the cerebrum of newborn Rattus norvegicus is thegroup stimulated by qari.
Stimulation of Male Voice during Pregnancy Results in Higher Expression of Brain Derived Neurotrophic Factor in Cerebellum of Newborn Rattus norvegicus Nurvy Alief Aidillah; Hermanto Tri Joewono; Widjiati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17011

Abstract

Background: Recent studies in the field of Fertomaternal Medicine show that stimulation in the uteruscan support brain growth and development. If in previous studies stimulation using several types of music,this study uses human voice which aims to analyze the effect of stimulation of male and female voices ondifferences in the expression of Brain Derived Neutrotrophic Factor (BDNF) in cerebellum of newbornRattus norvegicus. Methods: This type of research is true experimental with post test only control groupdesign. Rattus norvegicus was given stimulation of men voice and women voice on 6th day until 17th dayof pregnancy. The expression of BDNF was examined using immunohistochemistry. Results: The mean ±standard deviation of the expression of BDNF in the cerebellum is 4.20 ± 1.75 (without stimulation), 6.04± 1.58 (male voice stimulation), and 5.60 ± 2.43 (female voice stimulation). The results of statistical testsshow that there is a significant difference on BDNF expression between the control group and the groupstimulated with male voice with a significance value <0.05 of 0.045 Conclusion: Giving stimulation usingthe male voice during pregnancy shows a significant increase in the expression of BDNF in cerebellum ofnewborn Rattus norvegicus.
Co-Authors Abdullah, Aya Ali Achmad Zam Zam Aghasy Agnes Krisylva Agus Sulistyono Agustina Hidayati Agustina Mar&#039;atus Sholichah Ahmed, Samar A. A. Al-Qadhi, Tasnim Mohammed Aldika Akbar, Muhammad Ilham Ali Madinah Ali Medina Ali Medina Ali, Lamia A. S. Almothana, Hebah H. M. Alselwi, Sarah A. D. Alsoufi, Fardous G. Amila, Ukhti Mukminah ilmi Amishinta, Ancha Ayu Amishinta, Ancha Ayu Ancha Ayu Amishinta Andita Hapsari Andriani, Linda Aprilawati, Dwi Askandar Tjokroprawiro Ayu Putri Yani Binta Dwi Novitasari Chandra, Cecilia Felicia Dedi Kuswandi Dessy Hidayati Fajrin Diana Estu Rumahastuti Dwi Budi Santoso Dwi Nurdi Puspita Sari Dwi Puji Wijayanti Ecccita Raheestyningtyas Eka Fitriani Sujitno Eka Nasrur Maulana Eko Budi Koendhori, Eko Budi Ernawati Ernawati Esti Nugraheny Fajrin, Dessy Hidayati Fitria Desky Frisilia Octaviana Yolanda Gatut Hardianto, Gatut Hafiza Amadhin Rusti Hajj, Suha Ali Al Harry Mangasi Binsar Panjaitan Hasan, Helmia Henky Mohammad Masteryanto HERAWATI, LILIK Herlina Alvianti N Herlina Puji Angesti Herman, Sriyana Heryana, Achmad Yuniari Jihanifa Hega Salsabiila Jimmy Yanuar Anas Khanisyah Erza Gumilar Khasanah, Rima Nur Laksana, Muhammad Ardian Cahya Maramis, Margarita M. Maria Inge Lusida Martono Tri Utomo Mikra Latisfian Mikra Latisfian Mikra Latisfian Mohammed, Haitham T. S. Muhammad Adrianes Bachnas Muhammad Miftahussurur Muhdi, Nalini Nabeel Usama Okbah Nareswari Imanadha Cininta Marcianora Naura Ega Kahayani Nur Cholila Nur Laila Faizah Nurvy Alief Aidillah Nyna Puspa Ningrum Okta Margarita Susiana Pamarga Priyambodo Pitria Permatasari Pudji Lestari PUNGKY MULAWARDHANA, PUNGKY Rejeki, Purwo Sri Rio Wironegoro Risa Etika, Risa Sabrina Kemala Hapsari Sakina Samsriyaningsih Handayani Siti Nur Kholifah Siti Nur Kholifah Siti Nur Kholifah Sofiyanti Miftakhurohmah Sonea Venugopal Sulistiawati Sulistiawati Sulistiawati Sulistiawati Tanadi, Melina Rosita Thabet, Habib Thabit, Riyadh A. S. Ucik Nurul Hidayati Ukhti Mukminah ilmi Amila Ummah, Fithriyah Cholifatul Wardhana, Manggala Pasca Wati, Yunita Kholilaili Saras Widati Fatmaningrum Widjiati Widjiati w Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati, Widjiati Widjiati, DR Widjiati, DR Windhu Purnomo Yaner, Nurul Ramadhani Yanti Yanti Yasyviena Za’ima Elnabila Yulia Putri Permatasari Zumroh Hasanah