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Kepatuhan Minum Antibiotik Pasien Rawat Jalan di Klinik Yonkes 2/2 Kostrad Malang Rudy Mardianto; Nanang Ardianto; Pujianto Pujianto
Jurnal Kesehatan Hesti Wira Sakti Vol. 9 No. 2 (2021): Jurnal Kesehatan Hesti Wira Sakti
Publisher : Institut Teknologi, Sains, dan Kesehatan RS dr. Soepraoen Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47794/jkhws.v9i2.334

ABSTRACT Introduction: Bacterial resistance to antibiotics is such a serious problem that it must be handled appropriately. Adherence to taking antibiotics is an effort to prevent resistance. Antibiotics as anti-infectives are given in one cycle of therapy so they must be taken to the end to prevent resistance. This study aims to find out the compliance of taking antibiotics in outpatients at Yonkes 2/2 Kostrad Malang clinic. Methode: The research design is observational with a cross sectional study approach. The sampling techniques is purposive sampling and obtained 100 patients who meet the criteria of inclusion and exclusion. The study was conducted using questionnaires as well as drug use forms. Results: The results showed that the characteristic antibiotics used amoxycilin 79%, cefadroxyl 12% and metronidazole 9%. The length of antibiotic use of 3 days as much as 76% and 5 days as much as 24%. The results of measurements with questionnaires showed that the categories were good at 47%, the categories were quite 18% and the categories were less than 35%. Pill count methods showed that compliance was 49% and non-compliant 51%. Conclusion: The level of adherence to taking antibiotics with questionnaires and pill counts methods show relatively similar results. Keywords: Compliance, questionnaires, pill count

Edukasi tentang Suplemen Kesehatan dalam Menghadapi Covid-19 di Desa Sumbersuko Kabupaten Malang Rizta Widya Pangestika; Rudy Mardianto; Dzikrina Ilmanita; Nanang Ardianto
ABDI MOESTOPO: Jurnal Pengabdian Pada Masyarakat Vol 5, No 1 (2022): Januari 2022
Publisher : Universitas Prof. Dr. Moestopo (Beragama)

Covid-19 di Indonesia tersebar luas hampir di semua provinsi, termasuk Jawa Timur. Banyaknya informasi terkait produk suplemen kesehatan yang beredar di masyarakat dapat menimbulkan keresahan bahkan mengganggu pasokan bahan-bahan, termasuk beberapa produk suplemen kesehatan yang dibutuhkan selama pandemi. Kegiatan pengabdian masyarakat ini dilaksanakan di Desa Sumbersuko Kecamatan Wagir. Tujuan pengabdian masyarakat ini yaitu untuk meningkatkan pengetahuan mitra tentang suplemen kesehatan, mitra dapat mengetahui informasi tentang vitamin C, dan mengenal upaya untuk menghadapi COVID-19. Sasaran dari kegiatan pengabdian masyarakat ini adalah Kader Desa Sumbersuko. Metode pelaksanaan kegiatan yaitu dengan memberikan edukasi tentang suplemen kesehatan dalam menghadapi COVID-19. Peserta edukasi juga diberikan buku saku suplemen kesehatan dan vitamin C. Peserta sangat antusias dalam proses edukasi yang terbukti dengan munculnya banyak pertanyaan dari peserta. Dengan adanya kegiatan pengabdian masyarakat ini, Kader Desa dapat memahami tentang penggunaan suplemen kesehatan dalam upaya menghadapi COVID-19. Tindak lanjut kedepannya yaitu para Kader Desa akan menyampaikan kembali hasil informasi dan pengetahuan yang telah didapatkan kepada masyarakat desa.

Aplikasi Pengingat Minum Obat Di Desa Sumbersuko Kecamatan Wagir Kabupaten Malang Rudy Mardianto
Jurnal ABM Mengabdi Vol 8 No 2 (2021): Desember
Publisher : STIE Malangkucecwara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31966/jam.v8i2.951

The people of Sumbersuko village in Wagir sub-district, Malang district, on average, already have an Android-based smartphone. The medication reminder application found on the smartphone is not yet known and used. The training program for 12 health cadres is expected that they understand and are able to use the medication reminder application well. Training is given to health cadres so that they can disseminate information to the community. The methods used in the training were lectures, discussions and trials with smartphones by health cadres. Beginning with the introduction of medication reminder applications, techniques for downloading applications and filling in drug data. The medication reminder application is important for people who are undergoing treatment for chronic diseases such as diabetes mellitus, tuberculosis, hypertension and other diseases who must take medication uninterruptedly. Medication reminder applications can improve adherence. Compliance with taking medication is one of the factors that affect the success of treatment, so the presence of this application is appropriate when applied. The alarm in the medication reminder application will help especially the elderly in Sumbersuko village. The presence of a medication reminder application is expected to improve people's quality of life and reduce mortality and morbidity

ANALYSIS OF FACTORS AFFECTING THE ADHERENCE OF TAKING ANTITUBERCULOSIS DRUGS AT PUSKESMAS KOTA MALANG Rudy Mardianto
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.791

Tuberculosis (TBC) is an infectious disease caused by Mycobacterium tuberculosis. The high mortality rate from TBC is associated with cases of resistance due to low adherence to medication. This study aimed to determine the effect of age, number of family members, and family support on adherence to antituberculosis drugs. The study was observational using a cross-sectional design. The subjects were 52 outpatients with tuberculosis who met the inclusion and exclusion criteria during the July-August 2022 period at Puskesmas Malang. The results of the study of the most age were 26-35 years as much as 26.92%. The highest number of family members was 3-4 people at 61.54%. Most family support was in the strong category at 86.54%. The results of the ordinal regression test showed that age had a p value of 0.045. The number of family members had a p value of 0.127. Family support had a p-value of 0.040. The conclusion was that age and family support affected medication adce with (p < 0.05). The number of family members did not affect medication adherence (p > 0.05). Age, number of family members, and family support simultaneously influenced medication adherence by 23.7%, while 76.3% were influenced by other factors that were not studied. Keywords: Adherence to taking medication, Family motivation, Tuberculosis

HUBUNGAN PERSEPSI KUALITAS PELAYANAN KEFARMASIAN DENGAN KEPUASAN PELANGGAN DI APOTEK KAYLA FARMA MALANG Hana Fieky Cintikashalma Verlyndika; Nanang Ardianto; Rudy Mardianto; Wiwin Rohma Maulidah
Parapemikir : Jurnal Ilmiah Farmasi Vol 12, No 3 (2023): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v12i3.5848

Di era globalisasi, semakin berkembangnya kesadaran bahwa kesehatan adalah hal terpenting dalam kehidupan, dan kebutuhan akan fasilitas medis semakin meningkat.Hal ini mendorong penyedia layanan medis untuk menyediakan dan meningkatkan mutu pelayanan serta pengobatan preventif dan kuratif dengan tujuan meningkatkan kualitas hidup dan memuaskan pengguna layanan medis.Kualitas dianggap baik jika persepsi pelanggan pada pelayanan sesuai harapan dan sebaliknya. Penelitian ini menggunakan jenis kuantitatif “non eksperimental” korelatif menggunakan 100 responden yang merupakan pelanggan di Apotek Kayla Farma Malang periode Agustus 2023. Sampel diambil secara Accidental Sampling. Hasil menunjukkan bahwa 89% responden menilai bahwa persepsi kualitas pelayanan kefarmasian sudah sangat tinggi, begitu pula pada aspek kepuasan pelanggansebanyak 94% responden menyatakan bila kepuasan pelangganmasuk pada kategori sangat tinggi. Pengujian bivariat menunjukkan bahwa pada persepsi kualitas pelayanan kefarmasian dengan kepuasan pelanggan terdapat hubungan yang relevan dengan angkakurang dari 0,05 dan memiliki keeratan kuat dengan angka korelasi sebesar 0,697.

ANALYSIS OF FACTORS AFFECTING THE ADHERENCE OF TAKING ANTITUBERCULOSIS DRUGS AT PUSKESMAS KOTA MALANG Rudy Mardianto
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.791

Tuberculosis (TBC) is an infectious disease caused by Mycobacterium tuberculosis. The high mortality rate from TBC is associated with cases of resistance due to low adherence to medication. This study aimed to determine the effect of age, number of family members, and family support on adherence to antituberculosis drugs. The study was observational using a cross-sectional design. The subjects were 52 outpatients with tuberculosis who met the inclusion and exclusion criteria during the July-August 2022 period at Puskesmas Malang. The results of the study of the most age were 26-35 years as much as 26.92%. The highest number of family members was 3-4 people at 61.54%. Most family support was in the strong category at 86.54%. The results of the ordinal regression test showed that age had a p value of 0.045. The number of family members had a p value of 0.127. Family support had a p-value of 0.040. The conclusion was that age and family support affected medication adce with (p < 0.05). The number of family members did not affect medication adherence (p > 0.05). Age, number of family members, and family support simultaneously influenced medication adherence by 23.7%, while 76.3% were influenced by other factors that were not studied. Keywords: Adherence to taking medication, Family motivation, Tuberculosis

THE EFFECT OF HOME PHARMACY CARE EDUCATION ON BLOOD PRESSURE CONTROL AND KNOWLEDGE LEVEL OF HYPERTENSIVE PATIENTS AT KENDALSARI PUBLIC HELATH CENTRE MALANG Nanang Ardianto; Allis Soraya Setyokanti Winarning; Rudy Mardianto; Ayesi Dewi Safitri
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.1041

Hypertension is one of the ten most common degenerative diseases and has a high mortality rate. In 2020, the prevalence of hypertension in Malang City reached 35,641 cases. The role of pharmacists as caregivers in home pharmacy care can help to control hypertension and reduce morbidity. The main objective of this study was to determine the effect of home pharmacy care on hypertension patients’ knowledge and blood pressure management. This study used a quantitative experimental design with a Randomized Control Trial method, with a total of 34 respondents divided into 2 groups: the control group and the test group of 17 respondents each. Using an accidental sampling technique. The research location was Kendalsari Public Health Centre Malang in August 2023. Blood pressure data were measured using a tensimeter, and knowledge level data were obtained using a knowledge questionnaire. Data analysis was performed using paired and pooled t-tests. The results of the analysis of the effect of home pharmacy care on the level of patient knowledge about hypertension with a significance value (2tailed) p = 0.000, and analysis of the effect of home pharmacy care on systolic and diastolic blood pressure with a significance value (2tailed) p = 0.030. The results of this study concluded that home pharmacy care for hypertensive patients had a positive effect on blood pressure control and increased knowledge at the Kendalsari Public Health Center, Malang. Keywords: Home pharmacy care, hypertension, blood pressure control, knowledge level.

PENGARUH KEPATUHAN MINUM OBAT TERHADAP OUTCOME PASIEN EMFISEMA DI RUMAH SAKIT WAVA HUSADA MALANG Salsabila, Dia; Salmasfattah, Novyananda; Mardianto, Rudy
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 12 No 2 (2023): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v12i2.235

Emfisema merupakan bagian dari penyakit paru obstruktif kronik, dimana prevalensinya cenderung meningkat di Indonesia. Salah satu faktor pencetus utama emfisema adalah merokok. Laki-laki yang usianya diatas 60 tahun merupakan populasi yang paling rentan terkena emfisema. Untuk menjaga kualitas hidup pasien, maka diperlukannya kepatuhan minum obat untuk memberikan outcome yang baik bagi pasien. Penelitian ini bertujuan untuk mengetahui adakah pengaruh kepatuhan minum obat dengan outcome pasien emfisema yang menjalani pengobatan secara rawat jalan di Rumah Sakit Wava Husada Malang. Metode yang digunakan berupa deskriptif kuantitatif dengan pendekatan secara cross-sectional, menggunakan kuesioner MMAS-8 dan data rekam medis guna untuk menggumpulkan data. Hasil dari penelitian ini terdapat 80 responden yang dijadikan sebagai ukuran sampel penelitian. Berdasarkan pengelompokan gender, penelitian menemukan 47 responden (58,75%) adalah laki-laki. Terdapat 34 reponden (42,50%) berusia diatas 70 tahun. Pada obat-obatan yang digunakan diperoleh 79 resep (23,80%) mendapatkan obat salbutamol, paling banyak obat diberikan secara peroral (81,80%), serta diberikan secara kombinasi (98,75%) dari 80 responden ada 63 responden (78,75%) yang patuh terhadap pengobatan dan terdapat 57 responden yang tidak mengalami sesak (71,25%). Hasil uji binomial test menunjukkan nilai sebesar 0,000. Penelitian ini pengaruh antara kepatuhan minum obat terhadap outcome pasien emfisema di Rumah Sakit Wava Husada Malang. Kata kunci: emfisema, outcome, kepatuhan

Studi In Silico Glibenclamid Sebagai Kandidat Obat Antikanker Pada Inhibitor MAP2K1 dengan Metode Revers Docking Afiansyah, Ahmad Gasya; Mardianto, Rudy; Salmasfattah, Novyananda
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 16 No 1 (2024): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v16i1.2484

Tingkat keparahan efek samping yang terkait dengan obat antikanker yang saat ini beredar di pasaran termasuk efek samping yang berpotensi fatal seperti kardiotoksisitas pada kasus dokxorubisin. Penelitian ini bertujuan untuk menemukan kandidat obat baru yang memiliki efek samping rendah. Pendekatan in silico adalah metode komputasi untuk menemukan kandidat obat baru. Ligan glibenclamide dan doxorubicin diperoleh dari database PubChem, dan protein target MAP2K1, yang diperoleh dari database SwissModel, berfungsi sebagai reseptor. Pada penelitian ini ligan dan protein dipreparasi menggunakan alat PyMOL, dan hasil docking yang diperoleh dari alat PyRx berupa nilai afinitas pengikatan. Afinitas pengikatan antara protein dengan glibenclamide dan doxorubicin masing-masing adalah -9,9 kkal/mol dan -8,8 kkal/mol, hasil docking divisualisasikan menggunakan PyMOL. Senyawa tersebut mengikat glibenklamode kurang erat dibandingkan senyawa yang mengikat doxorubicin, tetapi masih berinteraksi kuat dengan protein MAP2K1. PLIP dapat digunakan untuk memvisualisasikan efek interaksi ini. Menurut temuan penelitian, senyawa glibenklamid memiliki interaksi yang baik dengan protein MAP2K1, sehingga menjadikannya target yang menjanjikan untuk obat kanker di masa depan. Untuk memvalidasi temuan ini, diperlukan lebih banyak penelitian biokimia, in vivo, dan in vitro.

Kepatuhan Minum Obat Mempengaruhi Kualitas Hidup Pasien TBC di Puskesmas Kota Malang Rudy Mardianto
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 14, No 4 (2023): Oktober - Desember 2023
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf14415

Treatment failure can be caused by low adherence to taking medication, which can have a negative impact on the health of TB patients. The aim of this research was to determine the effect of medication adherence on the physical, psychological, social and environmental health of TB patients. The design of this research was cross-sectional. This study involved 66 TB sufferers who received antituberculosis drugs, who were selected using a purposive sampling technique. The dependent variable was quality of life which consists of 4 domains, namely physical, psychological, social and environmental health and is measured by completing the WHOQoL questionnaire. The independent variable was medication adherence as measured by completing the MMAS-8 questionnaire. Data analysis was carried out using the logistic regression test. The results showed that the majority of patients were less compliant with taking medication (59.09%), while the physical health of the majority was high; the psychological health of the majority was high; the social health of the majority was low and the environmental health of the majority was high. The respective p values were physical health = 0.046; psychological health = 0.929; social health = 0.038; environmental health = 0.915. It was concluded that there was an influence of medication adherence on the physical and social health of TB patients in Malang city health centers.Keywords: medication adherence; quality of life; tuberculosis ABSTRAK Kegagalan pengobatan dapat disebabkan oleh rendahnya kepatuhan minum obat sehingga berakibat buruk terhadap kesehatan pasien TBC. Tujuan penelitian ini adalah untuk mengetahui pengaruh kepatuhan minum obat terhadap kesehatan fisik, psikologis, sosial dan lingkungan pada pasien TBC. Desain penelitian ini adalah cross-sectional. Penelitian ini melibatkan 66 penderita TBC yang menerima obat antituberkulosis, yang dipilih dengan teknik purposive sampling. Variabel dependen adalah kualitas hidup yang terdiri dari 4 domain, yaitu kesehatan fisik, psikologis, sosial dan lingkungan dan diukur dengan pengisian kuesioner WHOQoL. Variabel independen adalah kepatuhan minum obat yang diukur dengan pengisian kuesioner MMAS-8. Analisis data dilakukan menggunakan uji regresi logistik. Hasil penelitian menunjukkan bahwa mayoritas pasien kurang patuh minum obat (59,09%), sedangkan kesehatan fisik mayoritas adalah tinggi; kesehatan psikologis mayoritas adalah tinggi; kesehatan sosial mayoritas adalah rendah dan kesehatan lingkungan mayoritas adalah tinggi. Nilai p masing-masing adalah kesehatan fisik = 0,046; kesehatan psikologis = 0,929; kesehatan sosial = 0,038; kesehatan lingkungan = 0,915. Disimpulkan bahwa terdapat pengaruh kepatuhan minum obat terhadap kesehatan fisik dan sosial pada pasien TBC di puskesmas kota Malang. Kata kunci: kepatuhan minum obat; kualitas hidup; tuberkulosis

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