Article Per Year (5 Year)
p-Index From 2021 - 2026
2.064
P-Index
This Author published in this journals
All Journal Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Jurnal Aisyah : Jurnal Ilmu Kesehatan Narra J AKSONA Neurona Trends in Infection and Global Health
Paulus Sugianto
Departemen Neurologi FK Universitas Airlangga/RSUD Dr. Soetomo, Surabaya
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

Published : 14 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : Neurona

 1 
PENGUKURAN TINGKAH LAKU PADA MODEL NYERI NEUROPATIK PERIFER: TIKUS DENGAN CCI (CHRONIC CONSTRICTION INJURY) Hanik Badriyah Hidayati; Paulus Sugianto; Junaidi Khotib; Chrismawan Ardianto; Kuntoro Kuntoro; Mohammad Hasan Machfoed
NEURONA Vol 35 No 3 (2018)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v35i3.15

Abstract

BEHAVIORAL ASSESMENT OF THE PERIPHERAL NEUROPATHIC PAIN MODEL: RAT WITH CCI (CHRONIC CONSTRICTION INJURY)ABSTRACTNeuropathic pain occurs in 20% of patients with chronic pain. This mainly due to the lack of effective treatment and the presence of drug’s side effects. Animal models have been broadly utilized in validating the therapeutic target and the development of analgesic drugs. Chronic constriction injury (CCI) is a model of peripheral neuropathic pain characterized by allodynia and hyperalgesia. Chronic constriction injury model is produced by loose ligation of the sciatic nerve resulting in nerve damage, thus sensitizes and lowers pain threshold. The pain threshold test is performed by providing a pressure and thermal sensory stimulus that results in observable withdrawal behavior. This article discusses several methods in assessing pain-related behavior on the CCI neuropathic pain model.Keywords: Behavioral, chronic constriction injury, mechanical, neuropathic painABSTRAKNyeri neuropatik terjadi pada seperlima pasien dengan nyeri kronik. Hal ini disebabkan karena terapi nyeri neuropatik masih kurang efektif dan adanya efek samping obat. Model hewan terbukti bermanfaat untuk validasi target dan perkembangan obat analgesik. Chronic constriction injury (CCI) merupakan model nyeri neuropatik perifer dengan karakteristik alodinia dan hiperalgesia. Model CCI dibuat dengan memberikan ligasi longgar pada saraf skiatik yang menyebabkan kerusakan saraf, sehingga terjadi sensitisasi dan ambang nyeri menurun. Tes ambang nyeri dilakukan dengan memberikan stimulus sensorik berupa tekanan dan panas yang akan menghasilkan tingkah laku withdrawal yang bisa diobservasi. Artikel ini membahas penilaian tingkah laku nyeri pada model nyeri neuropatik CCI.Kata kunci: Chronic constriction injury, mekanik, nyeri neuropatik, tingkah laku
HUBUNGAN FAKTOR SOSIODEMOGRAFI TERHADAP SKOR QUALITY OF LIFE IN EPILEPSY INVENTORY-10 PASIEN EPILEPSI DEWASA DI RSUD DR. SOETOMO Dwiastri Iris Sarwastuti; Paulus Sugianto; Hanik Badriyah Hidayati; Azimatul Karimah
NEURONA Vol 38 No 3 (2021)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Several socio-demographic factors, such as age, sex, marital status, level of education, and employment status can determine adult epilepsy patients’ quality of life, which Quality of Life quantitively presents in Epilepsy Inventory-10 (QOLIE-10) score. Aim: This study was to understand the correlation between age, sex, marital status, level of education, and employment status on adult epilepsy patients’ QOLIE-10 score at Soetomo General Hospital. Methods: Analytical observational study using accidental sampling of adult epilepsy patients at Soetomo General Hospital in June 2019-December 2019 was implemented. Several socio-demographic factors were obtained, including age, sex, marital status, level of education, employment status, and their QOLIE-10 score calculation. Correlation analysis against the QOLIE-10 score was carried out, including the Spearman test for socio-demographic factors of age and level of education; and the Mann-Whitney test for socio-demographic factors of gender and marital status, and employment status. Results: Obtained a total of 47 samples with the most common characteristics such as aged 18-25 years (29.8%), male (53.2%), married (57.4%), had the last educational level in senior high school (68.1%), and unemployed (68.1%). Correlation analysis showed an insignificant relationship between age, sex, marital status, recent education, and employment status on the QOLIE-10 score of adult epilepsy patients (p≥0.05). Discussion: Age, sex, marital status, recent education, and employment status did not show a significant relationship to the QOLIE-10 score of adult epilepsy patients. Keywords: epilepsy, QOLIE-10
MANAJEMEN NON-OPERATIF ABSES SEREBELLUM Putri Irsalina; Paulus Sugianto
NEURONA Vol 38 No 3 (2021)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A brain abscess is a severe infection that needs to be treated early. The increased mortality for brain abscesses is caused by modern diagnostic imaging and antibiotics that can penetrate into the central nervous system and abscesses. A cerebellar abscess was reported, with the chief complaint of chronic progressive headache. Head contrast magnetic resonance imaging (MRI) results show the presence of a right cerebellar abscess with a source of infection with otitis media and mastoiditis. Prover antibiotics and contrast head MRI evaluation show resolution of abscess diameter. Keywords: Cerebral abscess, cerebellar abscess, otitis media
Co-Authors Agustinus Ruma Chrismawan Ardianto Deby Wahyuning Hadi Dika Chandra Bintari Dwiastri Iris Sarwastuti Edfina Rahmarini Fatih Nugraha Abdillah Fidiana Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Imas R. Palupi Isnin Anang Marhana Junaidi Khotib Karimah, Azimatul Kuntoro Kuntoro Lu Jordy Luhur Machin, Abdulloh Mayori Rachmawati Mohammad Hasan Machfoed Muhammad Hamdan Muhammad Ikbal Priya Nugraha Putri Irsalina Rachmi Kurniawati Rio Tasti Surpa Sudibyo, Devi Ariani Tamara Audrey Kadarusman Wardhani, Indrayuni Lukitra Wendy Amelia Sihombing