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All Journal Farmaka IDJP (Indonesian Journal of Pharmaceutics) PESAGI (Jurnal Pendidikan dan Penelitian Sejarah)
Ina Novianti
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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IMPLEMENTASI UNDANG-UNDANG NO. 7 TAHUN 1967 TENTANG VETERAN REPUBLIK INDONESIA DI BANDAR LAMPUNG Ina Novianti; Iskandar Syah; Maskun Maskun
PESAGI (Jurnal Pendidikan dan Penelitian Sejarah) Vol 1, No 1 (2013): PESAGI (Jurnal Pendidikan dan Penelitian Sejarah)
Publisher : FKIP UNIVERSITAS LAMPUNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (77.556 KB)

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Abstract: The implementation of government regulation No. 7, 1967 about Veteran ofRepublic of Indonesia in Bandar Lampung. Independence of the Republic of Indonesia is theresult of the struggle of the hero. Heroes, those who are still alive called Veterans. Award givenby the government in the form of benefits to Veterans. Allowances is set out in Article 9 of LawNo. 7, 1967 on the right of Veteran Republic of Indonesia set out in government regulations andregulatory president. So that the implementation of the provision of benefits based on thegovernment rules and regulations president. Is intended to determine how the implementation ofGovernment Regulation No. 7 1967 about the right of Veteran of Republic of Indonesia inBandar Lampung chapter 9. Based on data obtained in the field and interviews with seveninformants about Veterans benefits contained in the regulations in accordance with the fundsreceived by the Veterans, honor funds contained in the presidential decree in accordance withthe funds received by Veterans, health benefits provided by the goverment in accordance withthe received by Veterans, provision of transport provided by the Veterans as received byVeterans and received tax relief given by the goverment in accordance with the received byVeteran. So it can be concluded that the implementation of Government Regulation No. 7 1967about the right of Veteran of Republic of Indonesia in Bandar Lampung chapter 9 is realized inthe form of allowances set out in goverment rules and regulations Veteran received the presidenwith the Republik of Indonesia in Bandar Lampung is appropriate.Keywords : The Veteran of Republic IndonesiaABSTRAKAbstrak: Implementasi Undang-Undang No. 7 Tahun 1967 tentang Veteran RepublikIndonesia di Bandar Lampung. Kemerdekaan Negara Republik Indonesia adalah hasilperjuangan dari pahlawan. Pahlawan ini, bagi yang masih hidup disebut Veteran. Penghargaanyang diberikan oleh pemerintah kepada Veteran yaitu berupa tunjangan yang tertera dalampasal 9 Undang-Undang No. 7 tahun 1967 tentang hak Veteran Republik Indonesia. Besarnyatunjangan tertuang pada Peraturan Pemerintah dan Peraturan Presiden. Sehingga pelaksanaanpemberian tunjangan Veteran berpedoman pada Peraturan Pemerintah dan Peraturan Presiden.Maka, penelitian ini ditujukan untuk mencari tahu bagaimanakah pelaksanaan Undang-UndangNo. 7 tahun 1967 tentang hak Veteran Republik Indonesia Pasal 9 di Bandar Lampung.Berdasarkan data yang diperoleh di lapangan dan hasil wawancara dengan 7 informan tentangtunjangan veteran yang tertuang dalam Peraturan Pemerintah sesuai dengan dana yang diterimaVeteran, dana kehormatan yang tertuang dalam Peraturan Presiden sesuai dengan dana yangditerima Veteran, tunjangan kesehatan yang diberikan oleh pemerintah sesuai dengan yangditerima Veteran, penyediaan transportasi yang diberikan oleh pemerintah sesuai dengan yangditerima Veteran dan keringanan pajak yang diberikan pemerintah sesuai dengan yang diterimaVeteran. Jadi dapat disimpulkan bahwa Implementasi dari Undang-Undang No. 7 Tahun 1967tentang hak Veteran Republik Indonesia Pasal 9 di Bandar Lampung direalisasikan dalambentuk tunjangan-tunjangan dan tunjangan yang tertuang dalam Peraturan Pemerintah danPeraturan Presiden dengan yang diterima Veteran Republik Indonesia di Bandar Lampungadalah sesuai.Kata Kunci : Veteran Republik Indonesia
Comparative Dissolution Formulation and Test Simvastatin Ko-Crystal Tablets With Isonicotinamide As Coformer Sopyan, Iyan; Novianti, Ina; Abdassah Bratadiredja, Marline; Salsabila Hapsari, Raira; Setiawati, Ervina
Indonesian Journal of Pharmaceutics Vol 6, Issue 2, May - August 2024
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v5i3.55250

Abstract

Simvastatin is a statin drug used to lower plasma cholesterol in all types of hyperlipidemia. Simvastatin is included in BCS class II with poor solubility.  One of the efforts made to increase the solubility of simvastatin is the formation of co-crystals. Co-crystal is a modified type of crystal habit, which consists of two or more molecules in the same crystal lattice. The purpose of this study was to obtain the best excipient combination formula on the simvastatin co-crystalline tablet with isonicotinamide as a coformer and its comparable dissolution test results. The excipient combination optimization was carried out using a two-level factorial method. The optimized Avicel pH 102 and Primogel produced four combination designs on ready-made formulas, namely F1 Avicel pH 102: Primogel (79:2), F2 Avicel pH 102: Primogel (79:8), F3 Avicel pH 102: Primogel (85: 2) and F4 Avicel pH 102: Primogel (85: 8). The evaluation includes evaluating the mass of the print and the quality of the tablets. The excipient combination design solution in the best formula is Avicel pH 102 and Primogel with a ratio (79: 8). The method used in a comparable dissolution test is to compare the values of F1 (difference factor) and F2 (similarity factor) using BootStrap software. The F2 values observed were 50.3 at pH 1.2, 56.09 at pH 4.5, and 59.23 at pH 6.8, which indicates that the simvastatin co-crystalline tablet has similarities with the innovator tablet. The excipient combination design solution in the best formula is Avicel pH 102 and Primogel with a ratio (79: 8). The method used in a comparable dissolution test is to compare the values of F1 (difference factor) and F2 (equation factor) using BootStrap software. The F2 values observed were 50.3 at pH 1.2, 56.09 at pH 4.5, and 59.23 at pH 6.8, which indicates that the simvastatin co-crystalline tablet has similarities with the innovator tablet.Keywords: Simvastatin, co-crystal, two-stage factorial, comparable dissolution                     test.
NARRATIVE REVIEW : ALASAN PENARIKAN VALSARTAN DARI PEREDERAN DAN KAITAN NYA TERHADAP PENGAWASAN MUTU NOVIANTI, INA; Indradi, Raden Bayu
Farmaka Vol 20, No 3 (2022): Farmaka (November)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/farmaka.v20i3.38875

Abstract

Berdasarkan penjelasan BPOM RI pada Desember 2018 mengenai penarikan sutau produk obat antihipertensi di Indonesia yakni golongan angiotensin receptor blocker yaitu valsartan dikarenakan mengandung cemaran organik berupa N-Nitrosodimethylamine (NDMA) dan N-Nitrosodiethylamine (NDEA). Valsartan sendiri merupakan obat golongan Angiotensin Receptor Blocker yang memiliki indikasi sebagai antihipertensi. Penelitian ini bertujuan untuk mengaitkan alasan penarikan valsartan dari peredaran dengan pengawasan mutu nya. Metode yang digunakan yakni studi Pustaka dimana dilakukan pencarian data primer yang didapat dari website BPOM RI dan data sekunder dari hasil pencarian literatur sebagai sumber informasi yang relavan dengan identifikasi  jurnal-jurnal penelitian internasional maupun nasional dan mengacu kepada pedoman standar terhadap pengawasan mutu nya. Hasil penelitian menunjukan bahwa pengawasan mutu pada valsartan yang ketat harus diiringi dengan instrumentasi analitik yang sensitif dan andal, hal ini diperlukan untuk mendeteksi dan kuantifikasi zat pengotor nya, dan metode yang disarankan oleh FDA ialah menggunakan triple quadrupole GC-MS/MS, karena memberikan keuntungan dari segi peningkatan sensitivitas deteksi (terutama untuk NDEA) dan selektivitas yang sangat baik dalam susunan matriks obat valsartan
Co-Authors Abdassah Bratadiredja, Marline Indradi, Raden Bayu Iskandar Syah Iskandar Syah Iyan Sopyan Maskun Maskun Maskun Salsabila Hapsari, Raira Setiawati, Ervina