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All Journal The Indonesian Biomedical Journal Sari Pediatri Paediatrica Indonesiana Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Indonesian Journal of Cardiology Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology Jurnal Pengabdian Masyarakat Indonesia Sasambo Journal of Pharmacy Cermin Dunia Kedokteran Jurnal Pengabdian Kesehatan Masyarakat
Teddy Ontoseno
Airlangga University Medical School / Dr Soetomo Hospital Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Factors Associated with the Occurrence of Cyanotic Spells in Tetralogy of Fallot Patients Teddy Ontoseno
Paediatrica Indonesiana Vol 35 No 9-10 (1995): September - October 1995
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (570.434 KB) | DOI: 10.14238/pi35.9-10.1995.227-30

Abstract

A study was carried out on 114 tetralogy of Fallot patients attending the Department of Child Health, Medical School, University of Airlangga/Dr. Soetomo Hospital between 1 January 1988 to 31 December 1992. Only 81 patients fulfilled our study criteria where 52 (64.2'%) were cases with complications such as cyanotic spells, 4 (4 .93%) among them had brain abscesses. Twenty-nine individuals without complications acted as controls. Age, sex, nutritional status, hematocrit, MCHC and onset of symptoms between the two groups were analyzed using the multiple regression logistic. It has been shown that relative anemia, polycythemia and the age of 2-5 years contributed to the onset of cyanotic spells, respectively, R = 0.3171 and p = 0 .0004; R = 0.2220 and p = 0 .0073; R = 0.1363 and p = 0.00465. Therefore, in conventional treatment of tetralogy of Fallot patients it is essential to observe these risk factors in order to avoid complications and to improve the quality of life in these patients who are on the waiting list for surgery.
Peripheral Artery Embolism as a Complication of Infective Endocarditis in Mitral Insufficiency Gani Wangunhardjo; Teddy Ontoseno; Soebijanto Poerwodibroto; A. M. Prasodo
Paediatrica Indonesiana Vol 33 No 3-4 (1993): March - April 1993
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (962.374 KB) | DOI: 10.14238/pi33.3-4.1993.77-86

Abstract

Injective endocarditis in a 10 years old boy complicated by left brachial artery emboly in a case of rheumatic mitral insufficiency has been reported. The etiologic microorganism was coagulase positive Staphylococci. Though clinical cure was achieved by a 4 weeks long high dose of antibiotic (Ceftriaxone), peripheral artery emboly, had complicated the disease. Since adequate collateral circulation has already occurred, no specific treatment has been given. A further follow-up and injective endocarditis prophylaxis are still needed.
Correlation between Serum Ferritin and Heart Function in Children with Major Thalassemia at Dr. Soetomo Hospital Evisina Hanafiati Frans; Mahrus A Rahman; Teddy Ontoseno; I Dewa Gede Ugrasena; R Fatchul Wahabe
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 26, No 1 (2019)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v26i1.1401

Abstract

 Background: Cardiac hemosiderosis in major thalassemia has a high mortality rate. Serum ferritin levels are routinely performed to measure body iron deposit Early detection of cardiac dysfunction by routine echocardiography is very important to prevent complications due to hemosiderosis. Objective: To analyze correlation between serum ferritin levels and heart function in thalassemia major children. Methods: A cross-sectional study involving children of thalassemia major less than 18 years in the pediatric hematology oncology outpatient clinic at Dr. Soetomo Hospital. The subjects were children diagnosed with thalassemia major who had received more than 10 transfusions and had ferritin levels above 500 µg / L. All subjects were taken through consecutive sampling and performed echocardiography to measure right ventricular systolic function, left ventricular systolic function, and diastolic function. The factors analyzed included serum ferritin levels, TAPSE index, ejection fraction, and E / A ratio. Statistical analysis using chi square. Results: A total of 82 children were taken as the study sample that met the inclusion and exclusion criteria, 1 sample was dropped out due to pneumonia. Serum ferritin was not correlated to right ventricular systolic function (Cramer's phi constant 0.14, p = 0.209). Serum ferritin was not correlated with left heart systolic function (Cramer's phi constant 0.187, p = 0.09). Serum ferritin was not related to diastolic function (Cramer's phi constant 0.124, p = 0.264). Conclusion: Serum ferritin level in major thalassemia was not correlated with cardiac function
WEBINAR TRAINING OF EARLY DETECTION OF CONGENITAL HEART DISEASE FOLLOWED BY ECHOCARDIOGRAPHY AND PULSE OXIMETRY SCREENING IN LUMAJANG, EAST JAVA, INDONESIA Mahrus Abdur Rahman; I Ketut Alit Utamayasa; Teddy Ontoseno; Taufiq Hidayat; Henry Wicaksono
Jurnal Pengabdian Kesehatan Masyarakat Vol 3, No 1 (2022): Mei : Jurnal Pengabdian Kesehatan Masyarakat
Publisher : Program Studi Kesehatan Masyarakat Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jpkm.v2i2.13923

Abstract

Congenital heart disease (CHD) affects about 0.8% to 1.2% with the mortality rate being 81 cases per 100,000 live births. Generally, CHD is a structural abnormality of the heart and (or) large blood vessels that appear at birth. The purpose of this activity is to conduct webinar training on early detection of congenital heart disease followed by ecocardiography and oximetry pulse screening in lumajang east Java Indonesia the novelty in this service activity because it provides training on early detection of heart disease. The training method was carried out through webinars with health worker participants in Lumajang. The material provided includes early detection methods, diagnosis and therapy, as well as simulations of CHD cases. Pre and Post-test are used to evaluate the level of knowledge. A visit to the echocardiography and pulse oximetry examination by a pediatric cardiologist was carried out two weeks later in Lumajang. As a result of the activity, there were 140 participants who took part in the webinar training. The average score of the pre-test was 11.13/15 with only 5 participants getting a perfect score. At the end of the webinar, the average post-test score was 14.34/15 with 115 participants who finally got a perfect score. A total of 28 children were examined by echocardiography examination. 20 children were diagnosed with cyanotic CHD, 6 children were diagnosed with cyanotic CHD, and 2 were normal children. On pulse oximetry examination, all babies had an oxygen saturation of 95% or more and there was no difference of more than 3% between the pre and post duct sites. Conclusion Webinar training can increase health workers' knowledge about early detection of CHD.Keywords : Congenital Heart Disease; Filtering; Echocardiography; Pulse oximetry.
Tatalaksana dan Rujukan Awal Penyakit Jantung Bawaan Kritis Ihsanul Amal; Teddy Ontoseno
Cermin Dunia Kedokteran Vol 44, No 9 (2017): Kardiologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v44i9.732

Abstract

Penyakit jantung bawaan kritis adalah kelainan jantung yang memerlukan intervensi dini untuk bertahan hidup. Diagnosis dini disertai tatalaksana dan rujukan awal yang tepat berpotensi memperbaiki prognosis.Critical congenital heart diseases are a group of heart defect which requires an early intervention for survival. Early diagnoses followed by appropriate initial management and referral is potentially lifesaving. 
Correlation between Serum Ferritin and Heart Function in Children with Major Thalassemia at Dr. Soetomo Hospital Evisina Hanafiati Frans; Mahrus A Rahman; Teddy Ontoseno; I Dewa Gede Ugrasena; R Fatchul Wahabe
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 26 No. 1 (2019)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v26i1.1401

Abstract

Cardiac hemosiderosis in major thalassemia has a high mortality rate. Serum ferritin levels are routinely performed to measure body iron deposit Early detection of cardiac dysfunction by routine echocardiography is very important to prevent complications due to hemosiderosis. To analyze correlation between serum ferritin levels and heart function in thalassemia major children. A cross-sectional study involving children of thalassemia major less than 18 years in the pediatric hematology oncology outpatient clinic at Dr. Soetomo Hospital. The subjects were children diagnosed with thalassemia major who had received more than 10 transfusions and had ferritin levels above 500 µg / L. All subjects were taken through consecutive sampling and performed echocardiography to measure right ventricular systolic function, left ventricular systolic function, and diastolic function. The factors analyzed included serum ferritin levels, TAPSE index, ejection fraction, and E / A ratio. Statistical analysis using Chi-Square. A total of 82 children were taken as the study sample that met the inclusion and exclusion criteria, 1 sample was dropped out due to pneumonia. Serum ferritin was not correlated to right ventricular systolic function (Cramer's phi constant 0.14, p = 0.209). Serum ferritin was not correlated with left heart systolic function (Cramer's phi constant 0.187, p = 0.09). Serum ferritin was not related to diastolic function (Cramer's phi constant 0.124, p = 0.264). Serum ferritin level in major thalassemia was not correlated with cardiac function.
Peranan ACE-Inhibitor pada penyakit jantung bawaan Yusra Pintaningrum; Alit Utamayasa; Mahrus A. Rahman; Teddy Ontoseno; Ketut Angga Aditya Putra Pramana
Sasambo Journal of Pharmacy Vol. 4 No. 2 (2023): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i2.240

Abstract

Angiotensin-converting enzyme inhibitors have been shown to have the broadest impact of any drug in cardiovascular medicine. Dual role of ACE inhibitors, both preventing and treating cardiovascular disease. ACE inhibitors have an indirect effect on primary prevention by lessening hypertension and decreasing left ventricular hypertrophy, especially in patients with cardiac failure. In children, the causes of cardiac failure are significantly different and many cases are due to congenital malformations, such as left-to-right- shunts. In these patients, the function of both the right and the left ventricles will be affected and these children suffer from high-output cardiac failure. Therefore, in carefully selected patients with congenital heart disease, the response to systemic afterload reduction with ACE inhibitors appears favorable. Nevertheless, a more comprehensive controlled trial to assess the hemodynamic and functional effects of ACE inhibitors in such patients should be undertaken.
Deteksi Dini Penyakit Jantung Bawaan Melalui Pelatihan Webinar dan Screening Echocardiography di Kediri Mahrus A. Rahman; I Ketut Alit Utamayasa; Taufiq Hidayat; Teddy Ontoseno
Jurnal Pengabdian Masyarakat Indonesia Vol 3 No 4 (2023): JPMI - Agustus 2023
Publisher : CV Infinite Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52436/1.jpmi.1244

Abstract

Penyakit jantung bawaan (PJB) merupakan penyakit bawaan lahir yang paling banyak menimbulkan kematian. Kurangnya pengetahuan pada tenaga kesehatan menjadi hambatan dalam pencegahan dan deteksi dini PJB. Kegiatan edukasi yang bertujuan untuk meningkatkan pengetahuan tenaga kesehatan dalam melakukan deteksi dini dan penanganan PJB di Kediri perlu dilakukan. Kegiatan ini meliputi pelatihan webinar dan screening echocardiography dengan peserta tenaga kesehatan di Kediri. Tingkat pengetahuan peserta dinilai dengan pre-test dan post-test. Selanjutnya dilakukan screening echocardiography oleh Dokter Spesialis Anak Konsultan Jantung. Webinar diikuti oleh 451 peserta. Skor rata-rata pre-test adalah 5,80/15 dan skor rata-rata post-test adalah 12,84/15. Sebanyak 29 anak dilakukan pemeriksaan echocardiography. Terdapat 19 (65,52%) anak yang didiagnosis dengan PJB asianotik, 4 (13,79%) anak dengan PJB sianotik, dan 6 (20,68%) anak normal. Pelatihan webinar dapat meningkatkan pengetahuan tenaga kesehatan tentang deteksi dini PJB dan 79,31% anak yang telah dilakukan screening echocardiography didiagnosis dengan PJB di Kediri.
Hepatocellular Carcinoma with Inferior Vena Cava Thrombus in a Child Pratiwi, Fauziah; Prihaningtyas, Rendi Aji; Setyoboedi, Bagus; Ontoseno, Teddy
Current Internal Medicine Research and Practice Surabaya Journal Vol. 5 No. 1 (2024): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v5i1.49091

Abstract

Hepatocellular carcinoma (HCC) in children is the second common malignant liver tumor after hepatoblastoma. Chronic hepatitis B virus (HBV) infection causes most hepatocellular cancer worldwide. Metastases to the inferior vena cava (IVC) and right atrium (RA) tumor thrombi are even less common. We reported a case of a 13-year-8-month-old girl with HCC and IVC involvement. Vascular invasion predicts poor overall survival in HCC patients. Patients with HCC involving the IVC had a higher risk of sudden mortality and a poor treatment outcome. It is difficult to treat, and no standard therapy has been established. This case report aimed to describe HCC with IVC involvement. This is a rare disease with a poor prognosis, therefore it is important to detect and manage early.
Co-Authors A. M. Prasodo Alit Utamayasa Alit Utamayasa Amal, Ihsanul Ayu Pisita Wulandari Bagus Setyoboedi Bambang Permono Budiono Budiono Evisina Hanafiati Frans Fatchul Wahab Gani Wangunhardjo Harun Nurasid Henry Wicaksono I Dewa Gede Ugrasena Ihsanul Amal Kartika Hardiyani Ketut Angga Aditya Putra Pramana Mahrus A Rachman Mahrus A Rahman, Mahrus A Pratiwi, Fauziah Prihaningtyas, Rendi Aji R Fatchul Wahabe Renny Suwarniaty Rio Herdyanto Risa Etika, Risa S Suryono Sarmanu, Sarmanu Soebijanto Poerwodibroto Subijanto Purwodibroto Sudigdo Sastroasmoro Syamsul Arifin Taufiq Hidayat Umiastuti, Pirlina Utamayasa, I Ketut Alit Vinny Yoanna Yusra Pintaningrum