Rimbun Rimbun
Departemen Anatomi Dan Histologi, Fakultas Kedokteran Universitas Airlangga

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Association between Smoking Habit and Pulmonary Tuberculosis at Dr. Soetomo General Academic Hospita Balivia Andi Permata Hapsari; Prastuti Asta Wulaningrum; Rimbun Rimbun
Biomolecular and Health Science Journal Vol. 4 No. 2 (2021): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v4i2.30641

Abstract

Introduction: Smoking has been reported as one of tuberculosis (TB) risk factor. The association between smoking and TB has been proven in multiple studies, but little known about the association between smoking degree and sputum smear positive. Methods: An analytic observational study using cross-sectional design. Data of patients with pulmonary TB conducted at DOTS (Directly Observed Treatment Short course)/MDR (Multi Drug Resistance) outpatient and inpatient ward in Dr Soetomo General Hospital Surabaya from January to October 2018. The degree of smoking was measured using Brinkman Index (BI). The odds ratio (OR) and 95% confidence intervals (CI) were also estimated.Results: There were 94 patients with pulmonary TB, 56 non-smoker and 38 smoker. Light smoking (P = 0,120, OR = 0.200, 95% CI: 0.022-1.823), moderate smoking (P=0.377, OR = 1.667, 95% CI: 0.533-5.209), heavy smoking (P=0.076, OR= 0.333, 95% CI: 0.96-1.160). Moderate smoking compared to heavy smoking as a control (P=0.33, OR = 5.000, 95% CI=1.096-22.820). Conclusion: There’s no significant correlation between smoking habits and sputum smear positive, but the present study evidenced the patients with smoking habits had greater chance to get sputum smear positive than non-smokers. Patient with moderate smoking compared to heavy smoking had greater chance to get sputum smear positive.
GLUT 4 DI JARINGAN ADIPOSA (GLUT 4 in Adipose Tissue) Dewi Ratna Sari; Rimbun Rimbun; Tri Hartini Yuliawati; Joni Susanto; Ari Gunawan; Harjanto JM
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 21, No 1 (2014)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v21i1.1263

Abstract

The decreasing of glucose transporter 4 (GLUT 4) in adipose tissue of diabetic and obesity patients are associated withhyperinsulinaemia and insulin resistance. The adipose tissue can be used as therapeutic targets in the treatment of Diabetes Mellitus(DM). Visceral adipose tissue has different morphology and functional with subcutaneous adipose tissue and Vitamin D has been knownto have contributed in DM. The aim of this study is to know the role of cholecalciferol on the expression of GLUT 4 in subcutaneous andvisceral adiposity of diabetic rats by elucidated in those tissues. The subjects of the study consisted of nineteen male diabetic rats of Wistarstrain, which were divided into control group (K) and three (3) treatment groups (X1, X2 and X3). In order to induce the condition ofDM, the animals were fed with high fat diet for three (3) weeks and administered a single intraperitoneal injection of streptozotocin (35mg/kgBW) at the end of the second week. Cholecalciferol were administered with doses of 6.25 μg/kgBW in X1, 12.5 μg/kgBW in X2and 25 μg/kgBW in X3 per oral everyday within 14 days. The subcutaneous and visceral adipose tissues of the subjects were processedinto histological slides with immunohistochemistry staining. The data were analyzed by one way ANOVA test and paired t-test (α= 0.05,significance p<0.05). In this study was found the significance of GLUT 4 expression in subcutaneous adiposity (p=0.035) is differentbetween the groups, the differences were found between group K and groups X1, X2 and X3. Also there were found the significance differentof GLUT 4 expression in subcutaneous adiposities compared with visceral adiposities in all treatment groups (p>0.05). Based on thisstudy it can be concluded that cholecalciferol could increase the expression of GLUT 4 in the subcutaneous adiposity, but not in visceraladiposity of the diabetic rats.
ORGANIZING COVID-19 SURVIVORS AS CONVALESCENT PLASMA DONORS Erwin Astha Triyono; Rimbun Rimbun
Jurnal Pengabdian Masyarakat Dalam Kesehatan Vol. 4 No. 1 (2022): APRIL 2022
Publisher : Universitas Airlangga

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Abstract

Introduction: Convalescent plasma transfusion therapy remains as one of the therapies recommended by the Ministry of Health for Covid-19 patients in Indonesia. However, in its practice, this therapy is greatly constrained by the availability of plasma donors at the Indonesian Red Cross (PMI) and the few survivors who are willing to donate their blood plasma. The aims of the community service activity were to educate, organize, and facilitate the survivors to do screening and donate their plasma. Methods: The activities were conducted in June until December 2021, at Indrapura Field Hospital (RSLI) Surabaya. A total 925 participants (641 male and 309 female) were all Covid-19 patients from RSLI Surabaya. The demographic data were collected and organized as a database. The survivor's online communication group (16 WhatsApp groups) were created, to provide information and education about Covid-19 and the importance of plasma donation to the patients and survivors. Results: The three largest groups by age were 26-35 (30.84%), 46-55 (21.26%), and 36-45 (19.47%) years old. The 3 largest groups by city of origin were Surabaya (62.42%), Sidoarjo (16.53%), and Gresik (8.63%). About 77.89% of participants have their understanding in the convalescent plasma for Covid-19. About 43.79% of them were willing to become donors after 14-day-recovery, and have been registered in the web application of donors. The 102 survivors were also involved in free plasma screening with PMI Surabaya. Total 88 survivors who have passed the screening have given their plasma as convalescent donors. Conclusion: Organizing and educating Covid-19 survivors were exceptionally required to encourage them to become a plasma donor. The collected survivor data must be stored and managed properly to facilitate everything related to the blood plasma. The survivors are suggested to be screened 14 days after being declared healthy, to maintain the availability of blood plasma at PMI for Covid-19 patients who necessitate the convalescent plasma therapy.
The effect of interactive online learning on knowledge, attitude, and practice related to diabetes mellitus of productive-age population Bendix Samarta Witarto; Visuddho Visuddho; Teddy Yusuf; Rizqi Apsari Fairuz Kamila; Ghifar Akbar Iftinan; Clonia Milla; Salma Firdaus; Muhammad Wildan Nabalah Hartawan; Aisha Fairuz Zahira; Lintang Cahyaning Ratri; Amara Destania Armyne; Sulistiawati Sulistiawati; Rimbun Rimbun
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 2, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss2.art4

Abstract

Background: Diabetes mellitus still becomes a significant population health problem. In achieving sufficient awareness, face-to-face public education methods may serve as an effective measure. However, in the amid of pandemic, their implementation is restricted, which leads to the use of virtual platforms for learning activities. In addition, the applicability of the online learning method has yet to be explored.Objective: To evaluate its impact on the knowledge, attitude, and lifestyle practices of the productive-age population related to diabetes.Methods: A pre-test and post-test quasi-experimental study involving a single group was conducted among the productive-age population (aged 15 to 64 years) selected using consecutive sampling in two sub-districts in Surabaya, Indonesia. Baseline and endline levels of participants’ knowledge, attitude, and practice regarding diabetes assessed using a self-developed questionnaire were compared after receiving an educational intervention.Results: A total of 19 participants meeting the eligibility criteria were selected as the study subjects. A statistically significant increase in the participants’ knowledge score from pre- to post-test (p=0.038) was observed. There was no significant change between the pre-test and post-test scores of attitude (p=0.938) and practice (p=0.087) after the intervention.Conclusion: Online learning method improved the population’s knowledge regarding diabetes mellitus. However, it appears to have a limited role in providing better modification for attitude and practice. Further research comparing online and traditional face-to-face education methods are required to establish this approach as an alternative.