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All Journal Jurnal Anestesiologi Indonesia Jurnal Kedokteran Syiah Kuala Jurnal Pekommas Jurnal Berkala Epidemiologi Science and Technology Indonesia Paediatrica Indonesiana Health Notions Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Rochmanti, Maftuchah Rochmanti
Department Of Anatomy, Histology And Pharmacology, Faculty Of Medicine, Universitas Airlangga, Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Hypolipidemic Effects of Rosa Damascena Mill. Extract in Streptozotocin-induced Diabetic Rats Tamam Jauhar; Bilqis Inayatillah; Maftuchah Rochmanti; Achmad Basori
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14461

Abstract

Background: Diabetes mellitus is a chronic hyperglycemic condition with a lot of complication which canlead to death. Vascular complication in diabetes commonly caused by dyslipidemia which characterizedby decreased HDL, elevated LDL, Cholesterol and Triglyceride. Rosa damascena- an ornamental plantthoughts to have anti-hyperglycemia and antioxidant effects because of its large amount of polyphenoliccomponents . This study analyzed hypolipidemic activity properties of an ethanol extract of Rosa damascenaby measuring the lipid profile using various doses. Methods: This research is experimental study withrandomized post-test only control group design. Twenty male Wistar rats divided into 5 groups; The groupswere Healthy Control Group (HCG), Diabetes Group (DG), and Extract Group: P1 (250 mg/kgBW), P2(500 mg/kgBW), P3 (1000 mg/kgBW). All treatment groups were injected by single-dose streptozotocin50 mg/kgBW to induce diabetes, and given the Rosa damascena ethanolic extract oral treatment for 2weeks. Statistical results showed that Rosa damascena significantly decrease cholesterol (58.2±15.19), LDL(11±2.44) optimally in dose 250 mg/KgBW and triglyceride (96.7±44.2) optimally in dose 500 mg/kgBWafter 14 days. Conclusion: Rosa damascena extract seems to be great candidate for anti-hyperlipidemicdrugs.
The Antibacterial Effect of Ethanol Extract of Garlic (Allium sativum L.) on Methicillin Resistant Staphylococcus aureus (MRSA) In Vitro Utami Meilanie Putri; Maftuchah Rochmanti; Manik Retno Wahyunitisari; Rebekah J. Setiabudi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14918

Abstract

Objective: To determine the antibacterial activity of ethanol extract of garlic against Methicillin-ResistantStaphylococcus aureus. Method: Dilution test was performed on 9 different concentration of ethanol extractof garlic (1024, 512, 256, 128, 64, 32, 16, 8, 4 mg/mL) dissolved in DMSO 10% and MRSA suspensionon Mueller Hinton broth medium to determine the Minimum Inhibitory Concentration. The MinimumBactericidal Concentration was determined by the result of streaking of MRSA inoculation on the nutrientagar plate. Results: The observation through Mueller Hinton broth medium has shown turbidity both beforeand after incubation because of garlic ethanol extract color which is blackish-brown and thick, while in thenutrient agar medium, MRSA bacteria grew on the media with concentrations 4, 8, 16, 32, 64, & 128 mg/mL and unable to grow at concentrations of 256, 512, and 1024 mg/mL. Conclusion: The MIC of ethanolextract of garlic on MRSA could not be determined, and the MBC in this study was 256 mg/mL.
The Anti-Inflammatory Effect of ACE-I/ARBs Drug on hs-CRP and HDL-Cholesterol in CKD Patient Muhammad Iqbal Mubarok; Maftuchah Rochmanti; Mochamad Yusuf; Mochammad Thaha
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15878

Abstract

Chronic kidney disease (CKD) is progressive disease that closely related to the chronic inflammatory process.Angiotensin-Converting Enzyme Inhibitor (ACE-I)/Angiotensin Receptor Blockers (ARBs) is the main therapy in the management of CKD, based on the recent sudies stated that this drug have pleiotropic effects as anti-inflammation.The aim of this study is tosee the interaction of hs-CRP and HDL-Cholesterol to prove the role of ACE-I/ARBs as an anti-inflammatory treatment for CKD patient. In this study we compared hsCRP, HDL Cholesterol and HDL Cholesterol /hs-CRP ratio levels in CKD patients who consumeand do not consumeACE-I/ARBs. Forty eight samples of CKD patients were taken randomly and then separated into two group based on their consumption of ACE-I/ARBs, each group have 24 samples.There were significantly different of mean of hs-CRP, HDL Cholesterol, and HDL Cholesterol/hs-CRP ratio between group, the mean concentration of hs-CRP in the ACE-I/ARBs group was significantly lower than in non-ACE-I/ARBs group (1,48±0,81 vs 4,19±4,02; P= 0.038),the mean of HDL (48,95±13,05vs 41,50±12,31; P= 0,048).There were negative correlation between HDL Cholesterol and hs-CRP, positive correlation between HDL Cholesterol/hs-CRP ratio and eGFR.This result indicate that hs-CRP and HDL-Cholesterol monitoring very important in CKD patient.
The Profile of Pharmacological Treatment in Trigeminal Neuralgia Patients in The Period of January 2018-December 2018 Marlon Yutimma Roestam Moenaf; Maftuchah Rochmanti; Devi Ariani Sudibyo
Health Notions Vol 4, No 9 (2020): September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn40905

Abstract

Trigeminal neuralgia is a condition that affects the trigeminal nerve, that manifests in a series of stabbing like pain, and often described like electricity. Its treatment guideline is to prioritize pharmacotherapy until patient is well. The gold standard treatment for trigeminal neuralgia is pharmacotherapy of Carbamazepine. However, carbamazepine is proven to cause allergic reaction to some patients. This research aims to describe the pharmacotherapy that is given to patients. The regiments of pharmacotherapy in trigeminal neuralgia shows that CBZ is the main pharmacotherapy given, as it is the gold standard treatment. GBP is the is the second most pharmacotherapy given and a concoction medication of Paracetamol, Diazepam and Amitriptyline being the third most favored therapy. Neurotropic B Vitamins plays a big role, as a support in the therapy to maintain the health of the overall nervous system. The pain scale data shows that almost all patients have significant pain relieve. The therapy of trigeminal neuralgia in this study shows that CBZ is most favored as it is the gold standard, however not all AEDs are accessible. Almost all patients have significant pain relieve eventhough not using gold standard treatment. Keywords: trigeminal neuralgia; pharmacotherapy
Pengaruh gaya belajar, lama waktu belajar, dan mitra belajar terhadap nilai ujian utama mata kuliah ilmu kesehatan anak pada program studi S1 pendidikan dokter fakultas kedokteran Universitas Airlangga Candra Dwantara Ramadhan; Maftuchah Rochmanti; Nancy Margarita Rehatta
Jurnal Kedokteran Syiah Kuala Vol 19, No 3 (2019): Volume 19 Nomor 3 Desember 2019
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v19i3.12504

Abstract

Abstrak. Pediatri adalah spesialisasi ilmu kedokteran yang berkaitan dengan bayi dan anak-anak. Ada beberapa materi yang perlu dipelajari termasuk 14 bab di mana ada total 48 topik. Penelitian ini bertujuan untuk mengetahui pengaruh gaya belajar, lama waktu belajar, dan mitra belajar terhadap nilai ujian utama Ilmu Kesehatan Anak. Metode yang digunakan dalam penelitian ini adalah pendekatan cross-sectional. Menganalisis pengaruh antara variabel bebas dengan variabel terikat dengan menggunakan kuesioner. Sebagian besar gaya belajar mahasiswa semester 7 yang mengikuti ujian utama Ilmu Kesehatan Anak adalah gaya Visual (62,4%), Auditori dan Kinestetik memiliki persentase yang sama (18,8%). Mayoritas mahasiswa belajar lebih dari 2 jam (68%) sisanya kurang dari 2 jam (32%). Mayoritas mahasiswa belajar mandiri (58,4%) sisanya belajar dengan tutor teman sebaya (41,6%). Tidak ada pengaruh yang signifikan antara gaya belajar dan nilai ujian utama Ilmu Kesehatan Anak. Tetapi, ada pengaruh antara lama waktu belajar (p=0,033) dan mitra belajar (p=0,003) terhadap nilai ujian utama Ilmu Kesehatan Anak. Tidak ada pengaruh antara gaya belajar dan nilai ujian Ilmu Kesehatan Anak. Terdapat pengaruh antara lama waktu belajar, mitra belajar, terhadap nilai ujian Ilmu Kesehatan Anak. Kata kunci: gaya belajar, lama waktu belajar, mitra belajar. Abstract. Pediatrics is a medical science specialization related to babies and children. There are some material that needs to be studied including 14 chapters in which there are a total of 48 topics. This study aims to determine the influence of learning styles, length of study time, and learning partners on result of the main pediatric exam. The method used in this study is a cross-sectional approach. Analyzing the influence of independent variables with dependent variables using a questionnaire. Most of 7th semester student who attend the pediatric main exam in 2017 learning styles is visual (62,4%), Auditory and Kinesthetic have the same percentage (18,8%). Most of students study more than 2 hours (68%) the rest are below 2 hours (32%). Most of students study by themselves (58,4%) the rest are study with their friend as a tutor (41,6%). There are no correlation between learning style and the result of pediatric main exam. But there are a correlation between length study time (p=0,033) and learning partners (p=0,003) towards the result of pediatric main exam. There are no correlation between learning style and the result of pediatric main exam. But there are a correlation between length study time and learning partners towards the result of pediatric main exam. Keywords: learning styles, length of study time, learning partners.
Feed Instagram sebagai Media Edukasi dan Lomba Teka-teki Silang tentang COVID-19 dan Kesehatan Mental Maftuchah Rochmanti Rochmanti
Jurnal Pekommas Vol 6 (2021): Special Issue: The Role of Communication and Information Technology in the struggle ag
Publisher : BBPSDMP KOMINFO MAKASSAR

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30818/jpkm.2021.2060310

Abstract

Pandemi COVID-19 memberikan dampak pada beban kesehatan, ekonomi, dan tingkat tekanan psikologis yang sangat signifikan. Di samping hal tersebut, usia muda menjadi salah satu faktor risiko efek dari pandemic. Berdasarkan Sustainable Development Goals (SDGs) terutama poin ketiga yaitu “Good Health and Well-Being” untuk mewujudkan masyarakat yang sehat dan sejahtera khususnya selama pandemi diperlukan penyampaian informasi yang cepat dan akurat salah satunya menggunakan media sosial. Selama pandemi COVID-19 terjadi pembatasan kegiatan masyarakat sehingga penyebaran informasi sebagian besar melalui media sosial. Oleh karena itu, dalam meningkatkan pemahaman masyarakat mengenai COVID-19 dan kesehatan mental diperlukan adanya kegiatan seperti edukasi dan lomba Teka-teki Silang (TTS).  Edukasi dan lomba TTS dilakukan secara daring melalui media sosial Instagram dengan sasaran remaja dan dewasa muda. Edukasi secara daring dilakukan dengan melakukan posting feed Instagram pada tanggal 12 dan 13 Juli 2021 dan lomba TTS diadakan pada tanggal 14 juli 2021. Mayoritas peserta mendapatkan skor 100 (skor maksimal) dengan jumlah 18 peserta dari total 32 peserta. Rata-rata peserta yang mengerjakan 20 soal TTS mendapatkan skor 92,66 dari total skor 100 poin. Hasil kegiatan ini menunjukkan peserta memahami dan mengetahui materi edukasi yang diberikan.
RETROSPECTIVE STUDY: INITIAL PHARMACOTHERAPY PROFILE OF NEW ACNE VULGARIS PATIENTS Esravila Ariya Wibisono; Diah Mira Indramaya; Maftuchah Rochmanti
Jurnal Berkala Epidemiologi Vol. 8 No. 3 (2020): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V8I32020.236-245

Abstract

Background: Acne Vulgaris (AV) is one of the most common diseases in the field of dermatology and ranks as the eighth most prevalent disease worldwide. Early management of this potentially deforming skin disease may reduce the pathophysiological burden and improve the quality of life of patients. Purpose: This study aimed to determine the pharmacotherapy for new patients with AV. Methods: This cross-sectional study used new patients with AV of the Cosmetic Division of the Outpatient Skin and Venereal Health Unit, Regional Public Hospital (RSUD) Dr. Soetomo, from January to December 2013 that were descriptively presented. The variable was the pharmacotherapy given. This study used secondary data collection by looking at the patients’ medical records. The variables studied were acne lesions and pharmacotherapy regimens, including the administration route and the medicine used. Results: The number of samples that met the inclusion criteria was 951 patients. Comedonal acne was most commonly given topical tretinoin. Papulopustular acne was most commonly given a topical combination of clindamycin and tretinoin, while acne conglobata was most commonly given a combination of topical clindamycin and tretinoin with oral doxycycline. Conclusion: The new patients with comedonal acne were mostly prescribed topical tretinoin pharmacotherapy. A pharmacotherapy combination of topical clindamycin and tretinoin was given to most new patients with papulopustular acne, whereas new patients with conglobata acne were given a pharmacotherapy combination of topical tretinoin and clindamycin with oral doxycycline.
Combination Effect of The Extract of Avocado Leaf and Seed (Persea americana) on Level of Total Cholesterol, LDL, and HDL in Mice (Mus musculus) with Hypercholesterolemia Muhammad Rafif Alfian Dita; Indri Safitri Mukono; Maftuchah Rochmanti
Biomolecular and Health Science Journal Vol. 2 No. 1 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.642 KB) | DOI: 10.20473/bhsj.v2i1.13907

Abstract

Introduction: Traditional and herbal medicine are two of the primary treatments in a developing country. Both avocado leaf extract and avocado seed extract (Persea americana) have been proven to have an antihyperlipidemic effect in experimental animals. This study was conducted to analyze the effect of avocado leaf and seed extract in a combination form on total cholesterol, LDL, and HDL of hypercholesterolemia mice induced by high fat diet and duck egg yolk.Methods: The sample unit of this study consisted of 25 mice (Mus musculus) and divided into 5 groups: KO1 (control), KO2 (hypercholesterolemia group), KO3 (1st treatment group), KO4 (2nd treatment group), and KO5 (3rd treatment group). The induction phase was done for 35 days, whilst the treatment phase was done for 28 days. All data were analyzed using t test and one-way ANOVA.Results: Administration of the combination including avocado leaf and seed extract (CALSE) in all treatment group proved to decrease total cholesterol and LDL level in mice although it was not statistically significant (p=0,420; p=0,882). Meanwhile, CALSE had a different effect on HDL KO3 level with HDL KO4 and KO5 level, in which HDL KO3 level tended to decrease and HDL KO4 and KO5 level tended to increase.Conclusion: In conclusion, CALSE has the potential to act as an antihyperlipidemic agent which derive from flavonoid and saponin. The potential efficacy might be achieved in a combination rather than in an individual form.
Understanding Cardiopulmonary Resuscitation Determines the Readiness of Doing Basic Life Support 'Ulaa Haniifah; April Poerwanto; Agus Sobagjo; Maftuchah Rochmanti
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 13 No. 1 (2022): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V13I12022.13-17

Abstract

Introduction: Cardiopulmonary Resuscitation (CPR) is an emergency lifesaving procedure performed when the heart stops beating. Basic Life Support (BLS) is the initial action to save life-saving conditions. BLS is one of the most important components in CPR. BLS greatly determines the fate of the next life-threatening victim. This study aimed to know the relationship of understanding CPR to readiness to do BLS for students of Faculty of Medicine, Universitas Airlangga, Surabaya.Methods: This was non-experimental study using the design of analytic and descriptive statistics. The sample of this study was the students of Faculty of Medicine, class of 2015, Universitas Airlangga, Surabaya and was taken by probability sampling method with a simple random sampling technique. Data retrieval was performed by giving a questionnaire to 100 respondents. This study was conducted in February 2019. The results of this study were then analyzed by SPSS using the Spearman test.Results: The results of this study showed that the most level of understanding CPR was in the good category with 56 people (56%), while the readiness to do BLS was mostly in the moderate category with 55 people (55%). Based on the results of statistical tests using the Spearman test, there was a relationship between the level of understanding CPR and the readiness to do BLS for students of Faculty of Medicine, Universitas Airlangga, Surabaya.Conclusion: There was relationship between the level of understanding CPR and the readiness to do BLS for students of Faculty Medicine, Universitas Airlangga, Surabaya.
Impact of an antimicrobial resistance control program: pre- and post-training antibiotic use in children with typhoid fever Elfrida A. Rachmah; Maftuchah Rochmanti; Dwiyanti Puspitasari
Paediatrica Indonesiana Vol 56 No 4 (2016): July 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.992 KB) | DOI: 10.14238/pi56.4.2016.205-10

Abstract

Inappropriate use of antibiotics may lead to antimicrobial resistance. In 2012, Dr. Soetomo Hospital conducted training for pediatric residents on the proper use of antibiotics to limit antimicrobial resistance.Objective To evaluate the impact of a rational, antibiotic-use training program for pediatric residents on their antibiotic prescriptions for patients with typhoid fever.Methods A cross-sectional, analytic study was conducted. We collected data from children with typhoid fever who were hospitalized in Dr. Soetomo Hospital, pre- and post-training on antibiotic prescriptions. Children with other known bacterial infections or who were discharged on request were excluded. Antibiotic prescriptions were evaluated using Gyssens algorithm based on the local protocol. Chi-square test was used to compare the quality of antibiotic prescriptions, before (year 2012) and after (year 2013) the training.Results Forty-nine patients with 67 prescriptions in 2012 and 34 patients with 48 prescriptions in 2013 fulfilled the inclusion criteria. Patients’ ages ranged from 1-18 years. Diagnoses of uncomplicated and complicated typhoid were found in 74% and 26% of subjects, respectively. First line (chloramphenicol, thiamphenicol, ampicillin, trimetroprim and sulfametoxazol) and second line (ceftriaxone and cefixime) use were 72% and 28%, respectively. All patients were discharged in good condition. Appropriate use of antibiotics was noted in 61% of subjects in 2012 and in 81% of subjects in 2013 (P=0.036). The most common type of error in 2012 and 2013 was dosage imprecision (25% and 17%, respectively).Conclusion Training on appropriate use of antibiotics significantly improved the quality of antibiotics prescribed in children with typhoid fever in Dr. Soetomo Hospital.
Co-Authors 'Ulaa Haniifah Achmad Basori, Achmad Agus Sobagjo April Poerwanto Arifa Mustika Bilqis Inayatillah Bunga Priscilla Rotua Manurung Candra Dwantara Ramadhan Dewi Ratna Sari Dhea Safitri Ramadhani Diah Mira Indramaya Dwiyanti Puspitasari, Dwiyanti Elfrida A. Rachmah Erika Vitri Yulianti Esravila Ariya Wibisono Fachry Abda El Rahman Hana Letitia Anjani Indri Safitri Mukono, Indri Safitri Junaidi Khotib Lucky Prasetiowati ManikRetno Wahyunitisari Marlon Yutimma Roestam Moenaf Maulydia, Maulydia Maya Rahmayanti Mochamad Yusuf Mochammad Thaha Muhammad Iqbal Mubarok Muhammad Rafif Alfian Dita Nurlaili Susanti Pamungkas, Dimas Bathoro Bagus Purwanta, Marijam Rebekah Setiabudi, Rebekah Rehatta, Nancy Margarita Roihatul Muti’ah Rozana Alfi Sania Salsabila Fabianca Alsaid Sudibyo, Devi Ariani Tamam Jauhar Trisilya Mita Anggrek Utami Meilanie Putri Wungu, Citrawati Dyah Kencono