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All Journal Paediatrica Indonesiana Majalah Kedokteran Nusantara The Journal Of Medical School Indonesian Journal of Global Health research
Melda Deliana
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Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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Growth velocity in elementary school children with iron deficiency anemia after iron therapy Dina Lyfia; Melda Deliana; Hakimi Hakimi; Nelly Rosdiana; Bidasari Lubis
Paediatrica Indonesiana Vol 49 No 5 (2009): September 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (106.951 KB) | DOI: 10.14238/pi49.5.2009.249-52

Abstract

Background Iron supplementation in children with iron deficiencyanemia could decrease the incidence of stunting.Objective To study the effect of iron therapy on growth velocityin children with iron deficiency anemia.Methods A randomized clinical trial study was conducted atLabuhan Batu on November 2006 to May 2007. Iron deficiencyanemia was diagnosed if there were anemia, with mean corpuscular hemoglobin concentration <31 %, red cell distribution width index > 220, and Mentzer index> 13. Elementary school children (6-12 year old) with iron deficiency anemia were randomly assigned either to iron therapy group (children were given 6 mg iron/kg/day) or to placebo group for 3 months.Results Among 300 children recruited, there were 125 children,who suffered from iron deficiency anemia. After one month ofiron therapy, means of hemoglobin concentration were 12.4 g/dl in iron group and 11.7 g/dl in placebo group. There was a significant increase of height in iron group (129.9 (SD 7.58) em vs. 132.2 (SD 7.23) em) and in placebo (130.8 (SD 8.78) em vs. 128.7 (SD 8. 79) em), However, no significant difference was found in the mean of growth velocity between placebo and iron groups (2.1 (SD 0.01) em vs. 2.0 (SD 0.9) em.Conclusion There is a significant increase in height, but nosignificant difference between both groups in growth velocity.
Gangguan pertumbuhan sebagai komplikasi talasemia • mayor Nur Robbiyah; Hakimi dr; Melda Deliana; Siska Mayasari
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 1 (2014): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Beta-thalassemias major are a group of hereditary blood disorders disease. Growth disorders are afrequent complication of patient with Beta-thalassemias major. The pathogenesis of disorders is multifactorial and is mainly due to chronic anemia and hypoxia, chronic liver disease, zinc and folic acid deficiency, iron overload and intensive use of chelating agents. Proper management of each patient with beta-thalassemias major include early recognition of growth disorders and appropriate of iron chelation therapy is very important to improve the quality of life.Keywords : beta-thalassemias major; growth disorders
Gangguan fungsi hormon tiroid pada anak penderita infeksi susunan saraf pusat Rahmad Sumiko; Melda Deliana; Hakimi dr; Siska Mayasari Lubis; Karina Sugih Arto
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 3 (2014): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Dysfunction of thyroid hormone can occur in children with central nervous system (CNS) infections characterized by decreasing levels of triiodothyronine (T3). Severe CNS infections have symptoms such as seizures, respiratory failure, impaired consciousness, fever, and typical abnormalities on Elektroencephalografi (EEG). Central nervous system infected children with low T3 have tendency of lower survival rate compare to CNS infected children with low thyroxine (T4). Examination of thyroid hormone performed by using vena puncture and lumbar puncture. It was performed before treatment is given. Until now, there are onlyfew case reports of thyroid hormone dysfunction in children with central nervous system infections.Keywords : CNS infection, children, thyroid dysfunction
The Relationship Between Lipid Profile and the Incidence of Relapsing Nephrotic Syndrome in Children Utari Olivina Tarigan; Rosmayanti Syafriani Siregar; Syamsidah Lubis; Isti Ilmiati Fujiati; Melda Deliana; Cynthea Prima
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.7017

Abstract

Nephrotic syndrome (NS) is one of the most common chronic kidney diseases in children, characterized by massive proteinuria, hypoalbuminemia, edema, and dyslipidemia. Relapse occurs in most cases and contributes to worsening the disease course. Dyslipidemia is suspected to influence relapse risk, but the specific relationship between lipid profile and relapsing NS remains unclear. Objective to analyze the association between total cholesterol, triglycerides, LDL, and HDL levels with relapse incidence in children with nephrotic syndrome. A retrospective study was conducted on 66 children aged 2–18 years with NS treated at H. Adam Malik General Hospital, Medan, in 2024. Subjects were divided into relapsing (n=54) and non-relapsing (n=12) groups. Data were obtained from medical records and analyzed using the Mann-Whitney test and Spearman correlation. Triglyceride (p=0.007), LDL (p=0.013), and HDL (p<0.001) levels differed significantly between the relapsing and non-relapsing groups. Total cholesterol showed no significant difference (p=0.164). The mean albumin level was significantly lower in the relapsing group (2.9 g/dL vs. 4.1 g/dL; p<0.001). A significant negative correlation was found between albumin and triglyceride levels (r=-0.326; p=0.008). Triglyceride, LDL, and HDL levels are significantly associated with relapse in pediatric nephrotic syndrome. Hypoalbuminemia is also an important risk factor. Lipid profile evaluation can serve as a useful indicator in monitoring and managing relapses.
Co-Authors Arto, Karina Sugih Bidasari Lubis Cynthea Prima Dina Lyfia Fujiati, Isti Ilmiati Hakimi dr Hakimi Hakimi Nelly Rosdiana Nur Robbiyah Rahmad Sumiko Rosmayanti Syafriani Siregar Siska Mayasari Siska Mayasari Lubis Syamsidah Lubis Utari Olivina Tarigan