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All Journal Jurnal Kedokteran Brawijaya Majalah Kesehatan FKUB CRJIM (Clinical and Research Journal in Internal Medicine) Jurnal Penyakit Dalam Indonesia
Bogi Pratomo
Division of Gastroentero-hepatology, Department of Internal Medicine, Faculty of Medicine, University of Brawijaya/Dr. Saiful Anwar General Hospital, Malang
Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Journal : Jurnal Penyakit Dalam Indonesia

 1 
Comparison of Mortality between Intravenous Albumin and No Intravenous Albumin in Sepsis Patients with Hypoalbuminemia Conditions and Factors that Influence the Mortality of Sepsis Patients Marzuki, Mochammad Jalalul; Supriono, Supriono; Pratomo, Bogi; Mustika, Syifa
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 4
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Introduction. Hypoalbuminemia is a strong predictor of mortality in nonoperative and operative patients. Albumin plays a role in maintaining oncotic pressure in critical conditions such as sepsis. The administration of exogenous Human Serum Albumin (HSA) in sepsis with hypoalbuminemia conditions is still controversial with varying outcomes.This study aimed to know the mortality ratio between intravenous albumin administration and no intravenous albumin administration in sepsis patients with hypoalbuminemia conditions and also to know the factors that influence the mortality of sepsis patients. Methods. An observational study with a prospective approach involving 75 research subjects aged >18 years with sepsis accompanied by hypoalbuminemia (<2.5 g/dL) treated in the high care unit of RSUD dr. Saiful Anwar Malang during the period 1 September 2018-31 August 2019. Subjects were divided into two groups namely albumin and nonalbumin groups. Both groups were followed during hospitalization until they discharged or died. Differences in mortality between the two groups were analyzed by chi square bivariate test. The most influential factors on mortality were analyzed by multivariate binary logistic regression tests. Results. There were 39 people (52%) from the albumin group and 36 people (48%) from the non-albumin group. Difference in mortality between albumin and nonalbumin groups {25 (64.1%) vs 16 (44.4%) with OR 2, p=0.138} means there was no statistically significant difference. Factors that influence mortality included: SOFA score (OR 34.27, p <0.001), MAP value (OR 8, p<0.001), septic shock (OR 4.31, p=0.03), diabetes mellitus (OR 0.28, p=0.009), respiratory failure (OR 8.02, p <0.001), decreased of consciousness (OR 64.75, p <0.001), cardiovascular failure (OR 6, p <0.001), hematological failure (OR 3.05, p=0.027). The most dominant factor affecting mortality in sepsis patients is decreased of consciousness (OR 2.67, p=0.001). Conclusion. The administration of albumin transfusion did not make a significant difference in the incidence of mortality in sepsis patients with hypoalbuminemia. The most influential factor on mortality of sepsis patients is decreased of consciousness.
Arthritis in Chronic Hepatitis C Infection: Is It Rheumatoid Like Arthritis or True Rheumatoid Arthritis? Susanto, Jefri P.; Mustika, Syifa; Pratomo, Bogi
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 1
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The Effects of Curcumin on NF-κB Level and Degree of Liver Fibrosis in Rat Liver Fibrosis Supriono, Supriono; Pratomo, Bogi; Praja, Dedy Indra
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 4
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Gastroesophageal Reflux Risk Factor Analysis at Saiful Anwar Hospital in Malang Tarigan, Ricky C; Pratomo, Bogi
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 2
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Introduction. Gastroesophageal reflux disease (GERD) is a pathological condition as a result of reflux of stomach contents into the esophagus with various symptoms that arise due to the involvement of the esophagus, larynx, and airways. The prevalence of GERD has increased lately. In Indonesia, 22.8% cases of esophagitis were reported. Analysis of the risk factors for GERD is very important in reducing the prevalence of GERD. This study aimed to identify the most influential risk factors for GERD patients so that it could become a reference to reduce the prevalence of GERD in the following year. Methods. This study was a cross-sectional study where data was taken based on data from medical records of patients undergoing the endoscopic procedure in the division of Hepatology Gastroenterology at Saiful Anwar Hospital Malang during 2016. The diagnosis was obtained from history, physical examination, and GERD diagnostic criteria from endoscopy according to the Los Angeles criteria. Results. Among 57 patients, there were 20 female (32.5%) and 37 male (67.5%), 63.16% of them are >40 years old. This study found that 28 patients (49.12%) consumed herbs, 31 patients (54.38%) found smoking, and those who consumed alcohol were 18 patients (31.48%). The analysis showed that factors related to the incidence of GERD were herbal consumption (p=0.007; OR 4.586 (95% CI: 95%: 1.386-15.177)) and alcohol consumption (p 0.027; OR 4.846 (95% CI: 1.024-22.929)). Conclusion. Consumption of herbal and alcohol appear to be risk factors of the incidence of GERD in this study.
Co-Authors A.A. Ketut Agung Cahyawan W BP Putra Suryana Budi Herlianto Fachrureza, Mochamad Faridah, Amirah Hani Susianti Harijono Achmad Helena Helena, Helena Irawati, Ekamaya Sofa Komala, Anton Kriestian, Muhammad Marzuki, Mochammad Jalalul Nugraha Setiawan Nugraha, Bayu Eka Praja, Dedy Indra Praja, Dedy Indra Sasmithae, Lia Supriono Supriono Supriono Supriono Susanto, Jefri P. Syifa Mustika Tarigan, Ricky C Yoga Waranugraha