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All Journal ad-Dawaa : Journal of Pharmaceutical Sciences Current Research on Biosciences and Biotechnology Sasambo Journal of Pharmacy International Journal of Health, Engineering and Technology Journal Pharmacy of Tanjungpura
Muhammad Andre Reynaldi
Department Of Pharmacy, STIKES Arjuna, Laguboti District, Toba Regency, North Sumatra 22381, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : International Journal of Health, Engineering and Technology

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Antibacterial Activity of Crude Ethanolic Leaves Extract of Artocarpus heterophyllus Lam. Cultivated in Toba Region against Staphylococcus aureus Ayu Sibagariang; Muhammad Andre Reynaldi; Rony Sitohang
International Journal of Health Engineering and Technology Vol. 1 No. 5 (2023): IJHET - JANUARY 2023
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (592.167 KB) | DOI: 10.55227/ijhet.v1i5.99

Abstract

Jackfruit leaves (Artocarpus heterophyllus Lam.) was tested for its antibacterial activity against a human pathogenic bacterium, Staphylococcus aureus in vitro. Jackfruit leaves were collected from a forest region in the Toba Regency, North Sumatra and air-dried for five days. The dried leaves were crushed into powder to obtain simplicia and macerated using EtOH. The crude extracts were concentrated in vacuo using a rotary-evaporator and diluted into various concentrations (25, 50, 75, 100%) for antibacterial assay. The results showed that the antibacterial activity of extracts followed a concentration-dependent manner with the highest inhibition as expressed in the diameter of inhibitor zone reached 19 mm. The MIC50 value generated from a linear regression analysis between diameter of inhibition zone and concentration was determined at 10% of extract to display its effective concentration. The findings may be further investigated through phytochemical analysis and the selection of different organic solvents to maximize the bioactivity of jackfruit from this region.
Co-Authors Agnesia, Agnesia Amelia, Nanda Arif Setiawansyah Ayu Sibagariang Daryono Hadi Tjahjono Enggy Erwansani Fajriaty, Inarah Faradilla, Aulia Hafrizal Riza, Hafrizal Hakim, Aditia Rahman IH, Harianto Jaya, Farrel Septian Najini, Robby Rafika Sari Rony Sitohang Salsabila, Salwa Siti Nani Nurbaeti Sukrasno Valentina, Febriani