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PHYLLANTHUS NIRURI L TERHADAP IMUNITAS SELULER TIKUS Ima Arum L; Purwanto AP; Henna Rya
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 18, No 1 (2011)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v18i1.358

Abstract

Typhoid fever is a problem in the developing country. Phyllanthus niruri L (meniran) is a traditional plant that can be used as an immunomodulator on cellular or humeral immunity. By giving Phyllanthus niruri L extract to patient who suffers typhoid fever can increase cellular immunity responses in intracellular bacteria infection (S.typhimurium).This research was an experimental study using the post test-only control group design to proof of the effects of Phyllanthus niruri L on cellular immunity balb/c infected by salmonella typhimurium. The samples were taken from thirty male Balb/c mice which were divided into five groups including P1 (infected by S.typhimurium and PnL extract 125 g), P2 (infected by S.typhimurium and PnL extract 250 g), P3 (infected by S.typhimurium and PnL extract 500 g), K1 (infected by S.typhimurium) and K2 (healthy mice). In this study was applied parametric test of one way ANOVA and post hoc test Bonfferoni. It was known that phyllanthus niruri L increased the number of activated lymphocytes and phagocyte ability of macrophage (p=0.003 and p=0.001, respectively). By Bonfferoni post hoc test resulted that no significantly difference between the treated groups (increased of dose). There were no significant difference between the number of leukocyte, the difference count of lymphocyte and the nitrite oxide produced among the treatment groups and controls. Phyllanthus niruri L dose 250 μg increased the activated lymphocyte and index phagocytes. To find out the effects of Phyllanthus niruri L compare to antibiotic and Phyllanthus niruri L combination, continuing/advancing studies are needed
Training of Trainer (TOT) Dukungan Psikologis dan Self Empowerment Paska Bencana Bagi Staf dan Mahasiswa Fakultas Kedokteran Universitas Mataram Emmy Amalia; Ima Arum L; Sigit Kusdaryono
Jurnal Pengabdian Magister Pendidikan IPA Vol 2 No 1 (2019)
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (70.487 KB) | DOI: 10.29303/jpmpi.v1i2.305

Abstract

Abstract: Bencana adalah peristiwa atau rangkaian peristiwa yang mengancam dan mengganggu kehidupan dan penghidupan masyarakat yang disebabkan, baik oleh faktor alam dan/atau non-alam maupun faktor manusia sehingga mengakibatkan timbulnya korban jiwa manusia, kerusakan lingkungan, kerugian harta benda, serta dampak psikologis. Beberapa dampak psikologis yang sering muncul meliputi perubahan emosional akibat pengalaman traumatis, kekhawatiran akan kelangsungan hidup dan masa depan, dan kecemasan terkait keutuhan keluarga dan lingkungan sosial. Hingga bulan Agustus 2018, tercatat telah terjadi 395 kali gempa yang melanda Provinsi NTB, dengan beberapa gempa besar dengan pusat yang berbeda-beda. Gempa bumi yang melanda provinsi NTB sejak 29 Juli 2018 ini telah menelan banyak korban jiwa dan menimbulkan banyak kerusakan, sehingga tentu saja menimbulkan ketidakseimbangan kondisi psikologis masyarakat. Fakultas Kedokteran Universitas Mataram sebagai pusat pendidikan ingin berperan serta mengatasi dampak psikologis ini dengan mengadakan Training of Trainer (ToT) dukungan psikologis dan self empowerment paska gempa bagi staf dan mahasiswa kedokteran. Dengan konsep ToT, staf dan mahasiswa kedokteran tidak hanya diajarkan untuk mampu melakukan dukungan psikologis untuk dirinya sendiri, tetapi mampu mengajarkan ke orang lain di lingkungannya maupun kepada penyintas lain saat mereka ditugaskan di lokasi bencana. Kata kunci: Training of Trainer (TOT); Dukungan Psikologis; Self Empowerment
UJI DIAGNOSTIK PLASMODIUM MALARIA MENGGUNAKAN METODE IMUNOKROMATOGRAFI DIPERBANDINGKAN DENGAN PEMERIKSAAN MIKROSKOPIS Ima Arum L; Purwanto AP; Arfi S; Tetrawindu H; M Octora; Mulyanto Mulyanto; Surayah K; Amanukarti Amanukarti
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 12, No 3 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v12i3.871

Abstract

Microscopic examination is still a gold standard for malaria diagnostic tests. Immunochromatographic (IC) technique can be usedas an alternative examination. The aim is to compare the identification value of immunochromatographic method diagnostic test tomicroscopic examination of malaria in laboratory examination. Cross sectional diagnostic study approach was applied to those withsymptoms of: (1) fever (temperature > 38°C) or intermittent fever lasting for two days or more (2) cephalgia/myalgia, 604 sampleswere taken consecutively in January to July 2005 from primary health centres of Sukaraja and Keruak, as well as Clinic Nugraha atLombok Timur district , province of Nusa Tenggara Barat . From these samples, there were 37 samples with P.vivax, 45 samples with P.falciparum, 5 samples with mixed infection and 517 samples without Plasmodium sp. From IC examination, results were reserved for 36samples with P. vivax, 69 samples with P. falciparum, 5 samples with mixed infection and 503 samples without Plasmodium sp. Diagnostictest data analysis showed that the immunochromatographic test revealed 100% sensitivity, 96.7% specificity, 83.2% positive predictivevalue and 100% negative predictive value. It can be concluded that malaria IC test is reliable to be used as a routine malaria test.