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All Journal Medula Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati Human Care Journal

Firhat Esfandiari

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Author-ID : 3510689

Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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HUBUNGAN JUMLAH CD4+ DENGAN PENURUNAN HEMOGLOBIN PADA PASIEN TERINFEKSI HUMAN IMMUNODEFICIENCY VIRUS (HIV)/ACQUIRED IMMUNEDEFICIENCY SYNDROME (AIDS) DI RSUDDr. H. ABDUL MOELOEK BANDAR LAMPUNG TAHUN 2014 Firhat Esfandiari
Jurnal Medika Malahayati Vol 3, No 4 (2016): Volume 3 Nomor 4
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Latar belakang : Acquired Immunedeficiency Syndrome (AIDS) adalah suatu kumpulan gejala penyakit kerusakansistem kekebalan tubuh. Penyakit ini disebabkan oleh Human Immunodeficiency Virus (HIV) dan ditandai denganimunosupresi berat yang dapat menyebabkan komplikasi terjadinya anemia, yang ditandai dengan penurunaan jumlahCD4+. Sel limfosit CD4+ merupakan target utama pada infeksi HIV dimana sel ini berfungsi sentral dalam sistem imun tubuh.Pada mulanya sistem imun dapat mengendalikan infeksi HIV, semakin lama terinfeksi HIV akan menimbulkan penurunanjumlah sel limfosit CD4+ <200 sel/mm3, terganggunya homeostasis dan fungsi sel-sel lainnya dalam sistem imun tersebut.Tujuan : Mengetahui hubungan penurunan jumlah CD4+ dengan penurunan hemoglobin pada pasien terinfeksiHIV/AIS di RSUD Dr. H. Abdul Moeloek Bandar Lampung tahun 2014.Metode : Jumlah kadar CD4+ dan kadar hemoglobin didapatkan dari rekam medik pasien yang datang ke KlinikVCT Kanca Sehati RSUAM dr. H. Abdul Moeloek Bandar Lampung. Jenis penelitian ini adalah survey analitik denganrancangan cross-sectional study.Hasil : dari 60 responden didapatkan rerata hb pada pasien terinfeksi HIV/AIDS dengan CD4+ kurang dari 50sel/mm rerata Hb 6,7 gr/dL (11,7%), CD4+ 50-99 sel/mm rerata Hb 7,1 gr/dL (40%) dan CD4+ 100-200 sel/mm rerata Hb 9,4gr/dL (48,3%). Dengan pria mendominasi sebanyak 32 (53,3%). Rentan usia terbanyak 20-30 tahun sebanyak 27 (45%).Kesimpulan : Terdapat korelasi positif antara penurunan jumlah CD4+ dengan penuruunan kadar Hb. Semakinrendah CD4+ maka terjadinya penurunan Hb semakin besar.

GAMBARAN KARAKTERISTIK PENDERITA RHEUMATOID ARTHRITIS DI BAGIAN PENYAKIT DALAM RSUD Dr. H. ABDUL MOELOEK PROVINSI LAMPUNG 2013 Nimade dian pramasari; Hardiansa Timori; Firhat Esfandiari; Zulhafis Mandala
Jurnal Medika Malahayati Vol 1, No 1 (2014): Volume 1 Nomor 1
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Rheumatoid Arthritis (RA) adalah suatu penyakit autoimun dimana persendian (biasanya sendi tangan dan kaki)mengalami peradangan, sehingga terjadi pembengkakan, nyeri seringkali akhirnya menyebabkan kerusakan bagian dalamsendi. Prevalensi RA lebih besar pada perempuan dibandingkan laki-laki dengan perbandingan sebesar 3:1, insidenmeningkat dengan bertambahnya usia, terutama pada perempuan. Insiden puncak adalah antara usia 40-60 tahun.Beberapa gambaran klinis pada Rheumatoid Arthritis, misalnya biasanya mengeluhkan kekakuan dan nyeri sendi yangprogresif dan terkenanya banyak sendi secara simetris dalam waktu beberapa minggu sampai bulan.Jenis penelitian ini menggunakan penelitian studi deskriptif retrospektif. Populasi penelitian ini adalah seluruhpasien Rheumatoid Arthritis yang terdaftar di bagian penyakit dalam dan memiliki catatan Rekam Medik mulai dari Umur,Jenis Kelamin, Keluhan Utama dan Sendi yang terkena di RSUD Dr. H. Abdul Moeloek Provinsi Lampung 2013 berjumlah78 orang dengan sampel total populasi. Jenis data skunder yang tercatat di Bagian Rekam Medik. Analisis data denganmenggunakan tabel frekuensi.Hasil penelitian pada Distribusi Karakteristik penderita Rheumatoid Arthritis kebanyakan terdapat pada kelompokumur 47-53 tahun sebanyak 25 orang (32,1%), pada kebanyakan berjenis kelamin perempuan sebanyak 51 orang (65,4%)dibandingkan laki-laki 27 orang (34,6%), Nyeri sendi merupakan keluhan utama sebanyak 60 orang (76,9%), Lokasi sendiyang terkena kebanyakan Sendi tangan dan Kaki sebanyak 19 orang (24,4%).

HUBUNGAN LAMANYA SAKIT, USIA DENGAN KEPATUHAN MINUM OBAT PADA PASIEN SYSTEMIC LUPUS ERYTHEMATOSUS DI KOMUNITAS LAMPUNG TAHUN 2019 Okvien Puspita Sari; Resati Nando Panonsih; Ratna Purwaningrum; Firhat Esfandiari
HUMAN CARE JOURNAL Vol 5, No 4 (2020): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i4.734

Systemic Lupus Erythematosus (SLE) is a systemic disease with the characteristics of the antinuclear antibody (ANA) that attacks the vascular system and connective tissue. SLE is more common in women of childbearing age with a vulnerable age 15 to 45 years. To improve the quality of life, a Odapus (people with Lupus) should consume a variety of drugs all his life To determine the correlation between of the length of illness, age of the patient taking medication compliance Systemic Lupus Erythematosus in Comunity Lampung 2019. This type of research is research analytic method with cross sectional approach. Samples of this research that people with lupus in Lampung as many as 26 people. Data obtained through questionnaires filled medication adherence, age and informed consent questionnaire. Data analysis techniques to test the hypothesis that statistic Pearson. There research showed a correlation between age and medication adherence which from a statistical test Pearson gained significance level (p-value) amounted to (0.134), which means greater than the value of alpha (0.05) and no significant correlation between the duration of illness and whereby adherence of the statistical test Pearson gained significance level (p-value) amounted to (0.060), which means greater than the value of alpha (0.05).

KORELASI JUMLAH CD4 DENGAN KEJADIAN KANDIDIASIS ORAL PADA PASIEN TERINFEKSI HUMAN IMMUNODEFICIENCY VIRUS)/ CQUIRED IMMUNODEFICIENCY SYNDROM DI RSUD dr. H. ABDUL MOELOEK PROVINSI LAMPUNG PERIODE JANUARI-DESEMBER 2013 Yunita Sari Tanjung; Firhat Esfandiari
Jurnal Ilmu Kedokteran dan Kesehatan Vol 1, No 4 (2014): Volume 1 Nomor 4
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Kandidiasis merupakaninfeksi jamur yang disebabkan Candida danmudah terjadi pada orang yang mengalamipenurunan system imun, termasuk padapenderita HIV/AIDS. AIDS merupakankumpulan gejala penyakit yang disebabkanoleh menurunnya system imun akibat infeksivirus HIV dan kandidiasis merupakan infeksijamur yang sering terjadi. Penelitiansebelumnya yang dilakukan dibeberapa rumahsakit menunjukkan terdapat korelasi jumlahkadar CD4 dengan kejadian kandidiasis oral,semakin rendah jumlah kadar CD4, semakinmudah penderita HIV/AIDS mengalamikandidiasis oral.Tujuan:Mengetahui korelasi jumlah kadarCD4 dengan kejadian kandidiasis oral padapasien terinfeks iHIV/AIDS di RSUD dr. H.Abdul Moeloek Provinsi Lampung periodeJanuari-Desember 2013.Metode: Jumlah kadar CD4 dan data pasienterinfeksi kandidiasis oral didapatkan darirekam medic pasien yang datang ke KlinikVCT Kanca Sehati RSUAM dr. H. AbdulMoeloek. Jenis penelitian ini adalah surveyanalitik dengan rancangan cross-sectionalstudy.Hasil: Dari 50 responden, 43(86%) terinfeksikandidiasis oral dan 7(14%) tidak terinfeksi.Dengan jumlah kadar CD4 200-100 sel/μlsebanyak 2 responden (4,7%), CD4 100-50sel/μl7 responden (16,3%) dan 34 responden(79,1%) dengan CD4 ≤50sel/μl. Dengan priamendominasi yaitu 24 responden (55,8%).Rentan usia terbanyak 31-45 tahun sebanyak22(51,2%).Kesimpulan:Terdapat korelasi positif antarajumlah kadar CD4 dengan kejadiankandidiasis oral, didapatkan sebagian besarjumlah kadar CD4 <50sel/μl.

PERBANDINGAN ANGKA KESEMBUHAN ANTARA PASIEN COVID-19 YANG MEMILIKI KOMORBID DIABETES MELITUS DENGAN PASIEN COVID-19 TANPA KOMORBID DIABETES MELITUS DI RUMAH SAKIT NATAR MEDIKA NATAR TAHUN 2021 Firhat Esfandiari; Doni Rahman Nurdiana; Tusy Triwahyuni; Toni Prasetia
Medula Vol 12 No 2 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i2.367

COVID-19 is a disease caused by the SARS-CoV-2 virus. Most people infected with the virus can experience moderate to severe respiratory problems and recover without requiring special treatment. However, some will become severe and require medical treatment.Diabetes mellitus (DM) is a chronic disease that poses a challenge in the world of health, diabetes mellitus is one of the non-communicable diseases (PTM) which caused 1.6 million deaths in 2010. The cure rate among COVID-19 patients who have comorbid diabetes mellitus is higher. small compared to COVID-19 patients without comorbidities. Knowing the comparison of the cure rate of COVID-19 patients with diabetes mellitus as comorbid and COVID-19 patients without comorbidities at Natar Medika Hospital, Natar District, 2021. This study uses a descriptive-comparative research method with a cross sectional approach. Based on the results of this study, the majority of respondents were 71 respondents consisting of age > 45 years with a total of 50 patients (70.4%) the majority of respondents were women with 37 patients (52.1%) most patients with COVID-19 were without comorbid as many as 44 people (62%) of COVID-19 patients who recovered were more than COVID-19 patients who died, namely 59 patients (83.1%). In the results of statistical test analysis with Mann Whitney obtained p value = 0.000 (p <0.05) which means that there is a significant difference in the cure rate between COVID-19 patients who have comorbid diabetes mellitus and COVID-19 patients without comorbidities at Natar Hospital. Medika Natar in 2021.

HUBUNGAN ANTARA INDEKS MASSA TUBUH DENGAN TEKANAN DARAH SISTOLIK DI PUSKESMAS RAWAT INAP SIMPUR BANDAR LAMPUNG TAHUN 2022 Ika Artini; Sandhy Arya Pratama; Firhat Esfandiari; Richard Bartolomeus Alton
Medula Vol 12 No 3 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i3.380

Hypertension is a condition when a person has systolic blood pressure 140 mmHg and/or diastolic blood pressure 90 mmHg, on repeated examinations. The main blood pressure measurement that is the basis for determining the diagnosis of hypertension is diastolic blood pressure measurement. Hypertension with obesity is still very common. The prevalence of hypertension accompanied by obesity is also still increasing today. According to several studies, obesity and hypertension have a significant relationship. There are several explanations that patients who have a BMI with obesity will have a risk of 1.64 times to suffer from hypertension compared to BMI. Research Objectives To determine the correlation between body mass index degrees with blood pressure at public health center of Simpur in Bandar Lampung 2021. This type of research is quantitative research. With the analytical survey method using cross sectional design, through questionnaires given online to respondents who meet the inclusion criteria. Sample obtained was 97 respondents. The degree of blood pressure with the highest number of respondents was the degree of hypertension level 2 systolic >160 as many as 51 people (52.6%), the most age group were adult patients with an age range of 20-59 years as many as 66 people (68%), the degree of body mass index The highest number was obesity level 2 30 as many as 61 people (62.9%), the relationship between the degree of body mass index and the degree of blood pressure was mostly obesity level 2 with blood pressure of hypertension level 2 as many as 35 people (32.1%). Spearman test obtained p = 0.000 (p <0.05). There is a relationship between the degree of body mass index with the degree of blood pressure with the results of the Spearman test obtained p = 0.000 (p <0.05).

Co-Authors Doni Rahman Nurdiana Hardiansa Timori Ika Artini Nimade dian pramasari Okvien Puspita Sari Ratna Purwaningrum Resati Nando Panonsih Richard Bartolomeus Alton Sandhy Arya Pratama Toni Prasetia Tusy Triwahyuni Yunita Sari Tanjung Zulhafis Mandala

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