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All Journal Jurnal Ilmiah Manuntung Media Kesehatan Politeknik Kesehatan Makassar Journal of Pharmaceutical and Medicinal Sciences
Amriani Sapra
Sekolah Tinggi Ilmu Farmasi, Makassar
Agriculture, Biological Sciences & Forestry Health Professions Medicine & Pharmacology

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FORMULASI DAN EVALUASI LIP BALM LIOFILISAT BUAH TOMAT (SOLANUM LYCOPERSICUM L.) SEBAGAI PELEMBAB BIBIR Yusuf, Nurul Arfiyanti; Hardianti, Besse; Lestari, Indah Ayu; Sapra, Amriani
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (492.645 KB)

Abstract

The research on formulation and evaluation of lypholized tomato (Solanum lycopersicum L) as lip balm has been conducted. The objective of this research was to investigate the physical stability of lip balm formula from lypholized tomato that could enhance the lips? humidity. The formulation of lip balm was made into three concentration i.e 1%, 3%, and 5%. The physical stability evaluations that were performed before and after stress condition. Which is included organoleptic, homogeneity, and melting point test. The stable formula was then evaluated as skin moisture enhancer using skin analyzer. The results of this research showed that all three formula was physically stable. On the third formula (lypholized concentration of 5%) had the highest percentation of moisture enhancement with the significant difference among the three formulas.
Uji Difusi dan Iritasi Krim Solid Lipid Microparticle Ekstrak Etanol Daun Kersen (Muntingia calaura L.) Amriani Sapra; Radhia Riski; Nurul Hidayah
Jurnal Farmasi dan Ilmu Pengobatan Vol 4 No 1 (2019)
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (646.272 KB) | DOI: 10.32814/jpms.v4i1.74

Abstract

The extract of kersen leaves (Muntingia calabura L) contains flavanoid compounds as polar antioxidants which have difficulty to diffuse through the skin. Solid lipid microparticle is a drug delivery system to improve the availability of water-soluble compounds at site of action. The aim of this study was to determine diffusion profile and irritant effect of solid lipid microparticle cream loaded ethanol extract of kersen leaves. Diffusion of solid lipid microparticle cream loaded ethanol extract of kersen leaves was carried out using Whatman no.1 membrane and circumcision by franz diffusion methods while irritation test was performed on Albino rabbits (Orytoglagus cuniculus). The results of showed profil using Whatman membrane No. 1 are better than circumcision and the irritation test results the cream do not cause irritating effects on the skin.
EVALUASI KRIM ANTIOKSIDAN SOLID LIPID MICROPARTICLE EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura) Amriani Sapra; Radhia Riski; Besse Jamila
Media Kesehatan Politeknik Kesehatan Makassar Vol 15, No 1 (2020): Media Kesehatan
Publisher : Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (162.127 KB) | DOI: 10.32382/medkes.v15i1.1208

Abstract

ABSTRAK Kersen (Muntingia calabura L.) leaves is a plant that contains flavonoids as antioxidants which can be formulated in Solid Lipid Microparticle. The aim of this study is to make Solid Lipid Microparticle cream loaded ethanol extract of kersen leaves preparation and evaluated it’s physical stability. Solid Lipid Microparticle was made of 3% kersen leaves ethanol extract with entrapment efficiency 85.75% formulated in cream preparation with variation of cetyl alcohol concentration namely F1 (2%), F2 (4%), F3 (6%), then tested it’s stability before and after accelerated storage using climatic chamber. The results showed that the three formulas fulfilled the quality of preparation with organoleptic, homogenity, type of cream, viscosity, pH, and spreadability parameters before and after accelerated conditions. Keywords : Kersen leaves, Muntingia calabura L., physical stability, Solid Lipid Microparticle Cream 
AKTIVITAS ANTIOKSIDAN EKSTRAK LAMUN (Enhalus acoroides) ASAL PULAU LAE-LAE MAKASSAR TERHADAP RADIKAL ABTS Fitriyanti Jumaetri Sami; Syamsu Nur; Amriani Sapra; Libertin Libertin
Media Kesehatan Politeknik Kesehatan Makassar Vol 15, No 2 (2020): Media Kesehatan
Publisher : Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v15i2.1613

Abstract

Antioxidants are compounds that can inhibit or prevent oxidation reactions, which are the result of chemical reactions and metabolic processes that occur in the body. Enhalus acoroides is a type of seagrass found in Indonesian waters, generally living in sandy sediments with high bioturbation. Lamun has good nutrition and fiber so that it can be a source of food and medicine. The aim of this study was to examine the antioxidant activity of the seagrass extract Enhalus acoroides against ABTS radicals (2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid). The results of the study of seagrass extract using ethanol solvents had a very strong antioxidant category ie 38,008 µg /ml, the smaller the absorbance value, the higher the inhibitory value in which the antioxidant activity of the extract is higher, but when compared with the routine compound control of 0.500 µg /ml, seagrass ethanol extract is still lower.
Formulasi Sediaan Sabun Cuci Tangan Ekstrak Daun Kelor (Moringa Oleifera L.) dan Efektivitasnya Sebagai Antiseptik Amriani Sapra; Nur Khairi; Margaretha Margaretha; Andi Nur Aisyah; Maulita Indrisari; Fitriyanti Jumaetri; Noer Fauziah; Marwati Marwati
Jurnal Farmasi dan Ilmu Pengobatan Vol 6 No 2 (2021): JPMS Volume 6 Issue 2
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32814/jpms.v6i2.133

Abstract

Aim: The present research to formulate ethanol extract of Moringa oleifera leaf as a stable hand wash with required characteristics and evaluate it is effectivity against Escherichia coli and Staphylococcus aureus. Method: Moringa oleifera was extracted using 96% of ethanol. The obtained extract was formulated into hand wash in concentration 2.5; 5; and 7.5% w/v using surfactant sodium dodecyl sulfate and cocamide DEA. Obtained hand wash then evaluated the physical characteristics including organoleptic, pH, viscosity, relative mass, and foaming level. Hand wash effectivity evaluated against Escherichia coli and Staphylococcus aureus using diffusion method. Result: Hand wash of Moringa oleifera leaf extract fulfill the physical characteristics requirement and showing strong activity against E. coli. and S. aureus with average inhibition zone 13.1 mm; 13.8 mm; 14.5 mm; 12.9 mm; 15.16 mm; and 15.46 mm respectively for 2.5; 5; and 7.5% each. Conclusion: Overall, the experimental results revealed strong inhibition activity of M. oleifera hand wash to E. coli and S. aureus, but increasing the concentration of the extract has no significant different to inhibition activity.
Co-Authors Andi Nur Aisyah Besse Hardianti, Besse Besse Jamila Fitriyanti Jumaetri Fitriyanti Jumaetri Sami Indah Ayu Lestari, Indah Ayu Khairi, Nur Libertin Libertin Margaretha Margaretha MARIA BINTANG Marwati Marwati Maulita Indrisari, Maulita Noer Fauziah Radhia Riski Syamsu Nur Yusuf, Nurul Arfiyanti