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All Journal Medfarm: Jurnal Farmasi dan Kesehatan Jurnal EduHealth FORTE JOURNAL Jurnal Nusantara Berbakti Jurnal Siti Rufaidah
Jon Kenedy Marpaung
Universitas Sari Mutiara Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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KARAKTERISASI DAN SKRINING FITOKIMIA DARI TEPUNG BUAH BIT (Beta vulgaris L.) Siti Maimunah; Amila Amila; Jon Kenedy Marpaung; Vierto Irennius Girsang; Henny Syapitri
FORTE JOURNAL Vol 1 No 2 (2021): Edisi Juli 2021
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (159.702 KB) | DOI: 10.51771/fj.v1i2.141

Abstract

Buah bit (Beta vulgaris L.) merupakan tanaman yang banyak mengandung senyawa betalain. sumber utama pewarna merah alami. Salah satu inovasi pemanfaatan buah bit yaitu pembuatan tepung bit. Tujuan penelitian ini adalah mengetahui karakterisasi dan skrining fitokimia umbi bit, serta mengetahui tingkat penerimaan umbi bit yang dijadikan tepung bit bagi para panelis. Penelitian ini merupakan eksperimental dengan menguji kandungan senyawa kimia melalui uji karakterisasi dan skrining fitokimia. Hasil uji skrining fitokimia menunjukkan bahwa tepung bit (Beta vulgaris L.) memiliki senyawa alkaloid, tanin, saponin, flavanoid, steroid, glikosida gula, dan polifenol. Karakterisasi tepung bit dengan kadar air 9,28%, kadar abu total 0,99%, kadar abu tidak larut asam 0,82% dan kadar sari larut dalam air 0,82% dapat disimpulkan karakterisasi tepung buah bit memenuhi persyaratan Materia Media Indonesia (MMI). Uji Organoleptik dilakukan oleh 20 panelis, dengan kriteria penilaian sebanyak 9 panelis menyukai rasa, 6 panelis menyukai aroma, 12 panelis menyukai warna merah maroon, 12 panelis menyukai tekstrur, dan 11 panelis memiliki daya terima untuk tepung bit.
Anti Bacterial Activity Test of Ethanol Extract of Papaya Leaves (Carica papaya L) on the Growth of Staphylococcus epedermidis Jon Kenedy Marpaung; Monica Suryani; Ivan Elisabeth Purba
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.468 KB)

Abstract

Papaya is a tropical plant from the Caricaceae family, botanically defined as Carica papaya L. Traditional use of papaya leaves is to prevent bleeding in wounds and to treat wounds, lower high blood pressure, treat dengue fever, eliminate acne and smooth the skin and digestive disorders. Staphylococcus epidermidis is a Gram-positive bacterium, immobile, non-sporing, in solid culture media in the form of cocci in irregular groups, the arrangement is similar to grapes, prominent, shiny, does not produce pigment, white in color. Staphylococcus epidermidis bacteria can cause swelling (abscess) diseases such as acne, skin infections, urinary tract infections and swelling of the kidneys. This study was conducted with the aim of knowing the antibacterial activity of the ethanol extract of papaya leaves (Carica papaya L) with concentrations of 5%, 10%, 15%, and 20% against the growth of Staphylococcus epidermidis bacteria. This research method used an experimental method, namely to determine the antibacterial activity of the ethanol extract of papaya leaves (Carica papaya L) against the growth of Staphylococus epidermidis bacteria. This research used 96% ethanol as solvent. The test was carried out through several stages including material collection, preparation of simplicia, manufacture of ethanol extract from papaya leaves by maceration and testing of antibacterial activity against Staphylococus epidermidis bacteria. Based on the results of the phytochemical screening test of the thick extract, papaya leaves contain a class of alkaloid compounds, flavonoids, saponins, steroids/triterpenoids and tannins. The results of the antibacterial activity test of thick papaya leaf extract against Staphylococus epidermidis bacteria had an average inhibitory activity at concentrations of 5% (7.33 mm), 10% (8.44 mm), 15% (9.44 mm) and 20 % (10.3mm). As a comparison, Cloramfenocol 30 g was used to produce an inhibitory power of 32.1 mm and the best results obtained were at a concentration of 20% which had an inhibitory power of 10.3 mm.
PENGUJIAN EFEK DIURETIK INFUSA DAUN KOPI (Coffea arabica L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Ivan Elisabeth Purba; Bengi Simahara
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.139

Abstract

Diuretik bekerja pada ginjal dengan cara meningkatkan eksresi air dan natrium klorida. Kecenderungan masyarakat mengonsumsi diuretik berbahan kimia menyebabkan banyaknya efek negatif yang ditimbulkan. Penggunaan bahan alam sudah banyak diteliti untuk menggantikan obat-obatan kimia. Salah satu bahan alam yang memiliki khasiat yaitu tanaman kopi. Tanaman kopi yang digunakan bagian daunnya mengandung senyawa-senyawa antioksidan (flavonoid, alkaloid, saponin, kafein dan polifenol) yang bermanfaat sebagai anti inflamasi (anti peradangan), anti kanker, diuretik, antimikroba dan aktivitas antioksidan. Infusa Daun Kopi (IDK) diperoleh menggunakan teknik infusa dengan pelarut akuades kemudian digunakan pada 25 ekor tikus yang dibagi menjadi 5 kelompok. Kelompok I (negatif) Na-CMC 0,5 %, kelompok II (positif) Furosemid 3,6 mg/kgBB, kelompok III, IV, V IDK dosis 10, 20, 40% diberikan secara oral. Tikus diberi akuades secara oral dengan dosis 15 ml/kgBB. Tikus di letakkan di dalam kandang metabolik, kemudian pemeriksaan fisik urin dilakukan setiap 1 jam sekali selama 6 jam. Hasil penelitian menunjukkan bahwa IDK dengan dosis terbaik adalah 40% yang memberikan peningkatan volume urin, memberi pengaruh terhadap pH urin, memberi pengaruh terhadap berat jenis urin, memberi pengaruh terhadap warna urin dan memberi pengaruh terhadap kejernihan urin.
Bakti Sosial Pengobatan Gratis dan Penyuluhan Pengetahuan Tentang Tanaman Obat Keluarga (TOGA) Di Sekolah Tanjung Pura Langkat Monica Suryani; Jon Kenedy Marpaung; Suharyanisa Suharyanisa; Mestika Lumbantoruan
Jurnal Nusantara Berbakti Vol. 1 No. 3 (2023): Juli : Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v1i3.193

Abstract

Family medicinal plants (abbreviated as TOGA) are home-cultivated plants that have medicinal properties. A family medicine garden is essentially a plot of land, whether in the yard, garden or field, which is used to cultivate medicinal plants in order to meet the family's need for medicines. The purpose of this service activity is to provide social services for free medical treatment and dissemination of knowledge about family medicinal plants (TOGA) at the Tanjung Pura Langkat school. This method of activity involved lecturers at the Sari Mutiara Indonesia University, the regent, the sub-district head and the people of Langkat. The result of this activity is that the community service team hopes that the community can get free medication and knowledge about family medicinal plants. Based on the results of the Community Service activities carried out, these activities went well and the community received treatment and received knowledge about family medicinal plants so that the community could improve their health.
Pengujian Aktivitas Antihiperglikemia Infusa Batang Muda Rotan (Calamus Caesius Blume) Pada Tikus Putih Jantan (Rattus Norvegicus) Galur Wistar Yang Diinduksi Aloksan Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Dumartina Hutauruk; Juli Susanti
Jurnal Siti Rufaidah Vol. 1 No. 4 (2023): November : Jurnal Siti Rufaidah
Publisher : PPNI UNIMMAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jasira.v1i4.35

Abstract

Medicinal plants have been known and used worldwide for thousands of years. One type of medicinal plant that is often used is gaharu. The efficacy of gaharu leaves provides properties as a fever reducer, increases appetite, launches menstruation, and relieves pain. This study aims to determine whether there is an analgesic effect from the methanol extract of gaharu leaves in male Wistar rats using the heat stimulation method. This study was an experimental study using twenty-five male Wistar rats divided into five groups. Group I (negative control), rats were treated with 1% CMC-Na. Group II (positive control), rats treated with mefenamic acid 45 mg/kg BW. Group III, IV, and V rats were treated with gaharu leaf methanol extract suspension (100; 200, and 400) mg/kg BW. Pain stimulation was carried out by dipping the rat tail into a 40°C water bath. Data on response time to pain, stimuli were analyzed using the One-Way Analysis of Variance (ANNOVA) method with a 95% confidence level followed by a post-hoc Tukey test to determine which group had the same or significantly different effect. The results showed that the normal response time data for mice to painful stimuli ranged from 2.79 to 3.57 seconds. 1% CMC-Na treatment in mice was unable to increase the response time to a significant pain stimulus (p>0.05). Mefenamic acid treatment 45 mg/Kg BW significantly increased the response time to painful stimuli (p<0.05) with the longest average response time to painful stimuli, namely 8.87 seconds. Based on the method used in this research, methanol extract of agarwood leaves 400 mg/kgBW has almost the same analgesic effect as mefenamic acid 45 mg/KgBW.
Co-Authors Amila Amila Bengi Simahara Dumartina Hutauruk Henny Syapitri Ivan Elisabeth Purba Juli Susanti Lumbantoruan, Mestika Monica Suryani Siti Maimunah Suharyanisa Suharyanisa Vierto