Claim Missing Document
Check
Articles

Found 7 Documents
Search

Antibacterial Activity Test of Ethanol Extract of Mangkokan Leaves (Polyscias scutallarium (Burm.f.) Fosberg) against Escherichia coli and Staphylococcus aureus Deri Islami; Vonny Kurnia Utama; Dian Mayasari; Yan Hendrika
JURNAL PROTEKSI KESEHATAN Vol 10 No 2 (2021): JPK: Jurnal Proteksi Kesehatan
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v10i2.374

Abstract

Mangkokan is one of traditional medicinal plants that has many benefits in restoring health, such as preventing hair loss, treating wounds, antibacterial agent, improving blood circulation and as an antioxidant agent. This study aimed to examine the activity of the ethanol extract of the mangkokan leaf (Polyscias scutellarium (Burm.f.) Fosberg) against Escherichia coli and Staphylococcus aureus. The extraction process was carried out by gradual maceration through three solvents including n-hexane, ethyl acetate, and ethanol. The antibacterial activity test was carried out by agar diffusion method by calculating diameter of the inhibition zone from ethanol extract of mangkokan leaf with four variation concentrations: 20%, 40%, 60%, and 80%. The antibacterial activity of the ethanolic extract of the mangkokan leaf against Escherichia coli resulted in the average diameter od the inhibition zone at the following concentrations: 20% (5,9 mm), 40% (5,2 mm), 60% (5,9 mm), dan 80% (7,03 mm. While antibacterial test against Staphylococcus aures resulted in the average diameter of the inhibition zone at the following concentrations: 20% (9,66 mm), 40% (10,71 mm), 60% (11,27 mm), 80% (12,42 mm).
Gel Preparation Using Matoa Leaf (Pometia pinnata) Ethanol Extract: Formulation and Physical Evaluation Vonny Kurnia Utama; Yan Hendrika; Fuji Astuti
JURNAL PROTEKSI KESEHATAN Vol 11 No 1 (2022): JPK: Jurnal Proteksi Kesehatan
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v11i1.499

Abstract

Matoa leaves (Pometia pinnata) contain antioxidants that can prevent premature aging due to free radical damage to skin cells, reduce dark spots, acne, and improve collagen performance in the skin. The gel preparation was chosen because it provides a feeling of coolness, moisture, and good absorption on the skin and is easily washed off with water. The purpose of this research is to create a gel formula and conduct a physical evaluation of the ethanol extract of matoa leaf gel. This study employed an experimental method in which gel preparations were made from ethanol extract of matoa leaves at concentrations of 2%, 3%, and 4%. The organoleptic test results are thick, clear, light green, dark green, and dense dark green, with a distinct smell of ethanol extract of matoa leaves. F0, F1, F2, and F3 all pass the homogeneity test. The pH test results for F0, F1, F2, and F3 are 4-5. F0, F1, F2, and F3 dispersion tests were 6.1 cm, 5.3 cm, 5.7 cm, and 5.5 cm, respectively. As a result, the ethanolic extract of matoa leaves can be formulated as a gel preparation with favorable physical results.
Peningkatan Kualitas Minyak Ikan Patin (Pangasius hypophthalmus) dengan Penambahan Minyak Sereh Sebagai Antioksidan Vonny Kurnia Utama; Azlaini Yus Nasution; Yan Hendrika; Heri Safitri
Jurnal Pendidikan dan Konseling (JPDK) Vol. 5 No. 1 (2023): Jurnal Pendidikan dan Konseling
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jpdk.v5i1.11718

Abstract

Ikan patin merupakan salah satu ikan air tawar yang bisa dijadikan sumber asam lemak karena mempunyai kandungan minyak tinggi. Ada proses oksidasi bisa menyebabkan kerusakan pada minyak yang ditandai dengan ketengikan. Penambahan antioksidan diperlukan untuk mencegah terjadinya reaksi oksidasi. Penelitian ini bertujuan untuk mengetahui kualitas minyak ikan patin (Pangasius hypophthalmus) dengan penambahan minyak sereh sebagai antioksidan alami. Metode yang digunakan untuk mengetahui kualitas minyak ikan pada penelitian ini adalah metode titrasi dengan mengukur angka peroksida dan jumlah asam lemak bebas. Hasil penelitian menunjukkan bahwa setelah penyimpanan selama 7 hari angka peroksida minyak ikan larutan kontrol meningkat 0,51 meq/kg, sedangkan angka peroksida larutan uji dan larutan pembanding meningkat 0,37 meq/kg dan 0,97 meq/kg masing-masingnya. Kadar asam lemak bebas minyak ikan baik larutan kontrol, larutan uji, dan larutan kontrol adalah 0,25%, 0,08%, dan 0,08%. Berdasarkan hasil yang diperoleh dapat disimpulkan minyak sereh dapat menghambat kenaikan angka peroksida dan kadar asam lemak bebas pada minyak ikan patin.
Formulasi Sediaan Krim dari Ekstrak Kulit Batang Menteng (Baccaurea racemosa) Vonny Kurnia Utama; Kony Putriani; Sabrina Hayati
Jurnal Ilmu Kesehatan Abdurrab Vol. 2 No. 3 (2024): Volume 2 Nomor 3 September 2024
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Stem bark of the menteng (Baccaurea racemosa) contains antioxidant phenolic and flavonoid compounds capable of stopping free radical chain reactions. This research aims to make a formula for cream preparation and to find out the antioxidant activity of cream extract from the stem bark of the menteng (Baccaurea racemosa). The study used experimental methods to make a 96% ethanol extract cream with concentrations of 0,5%, 1,5%, and 3%. The results of a semisolid shaped organoleptic test with a typical fragrance of brown, brown, and old brown brown bark extract, homogenity tests F0, F1, F2, and F3, are homogeneous. The pH tests F0 (5), F1 (4,5), F2 (4,7) and F3 (4,8). The spreadability tests F0 (6,2 cm), F1 (6,1 cm), F2 (5,9 cm) and F3 (5,6 cm). Viscosity tests F0 (887,73 cPs), F1 (748,06 cPs), F2 (839,43cPs) and F3 (817,03cPs). Testing antioxidant activity using UV-Vis spectroscopic photometers obtained a wavelength of 516,80 nm with an absorption value of 0,725 in formula 1 (extract concentration of 0,5%) obtained an IC50 value of 51,41, in formula 2 (extract concentration of 1,5%) obtained an IC50 value of 63,43, and in formula 3 (extract concentration of 3%) obtained an IC50 value of 48,91. The antioxidant content of formulas 1 and 2 has strong antioxidant activity whereas formula 3 has a significant amount of antioxidant activity.
Formulation and Physical Characterization of Spray Gel Containing Collagen Extracted from Catfish (Pangasius hypophthalmus) Skin Vonny Kurnia Utama; Nabila Fitri Anugrah
Jurnal Ilmu Kesehatan Abdurrab Vol. 3 No. 1 (2025): Volume 3 Nomor 1 Maret 2025
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Collagen is a natural protein found in vertebrate and invertebrate animals. Collagen can be found in bones, skin and cartilage. Collagen from fish skin can hold water well and does not trigger irritation, so it is very good to apply to the skin, one of which is to make a spray gel preparation. In this study, collagen was obtained from the skin extraction of catfish (Pangasius hypophthalmus). The aim of this research is to determine the effect of Na CMC concentration on the physical properties of spray gel and to determine the concentration of Na CMC that meets the requirements for spray gel preparations. The process of making collagen is carried out by soaking using 0.3% NaOH and 0.1% citric acid. Based on the research results, collagen from catfish skin produced a yield of 8.46%, collagen in powder form, grayish white. Collagen powder was formulated into 4 spray gel formulas using Na CMC as the gelling agent and varying the gelling agent concentration starting from 2 5%. The preparations formed will be evaluated. During the evaluation of the spray gel, it was found that the F1 F4 preparations met the organoleptic quality standards, homogeneity, dry time and pH. However, the viscosity and spreadability do not meet the requirements.
Analysis Of Lead (Pb), Zing (Zn), and Copper (Cu) Levels in Catfish (Pangasius hypophthalmus) From Kampar Regency Using Atomic Absorption Spectrophotometry Subardi Bali; Vonny Kurnia Utama; Sri Kartini; Dwi Hestia Anjani
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 2 (2026): Volume 4 Nomor 2 Juni 2026
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Heavy metal contamination in aquatic environments has become a serious issue due to its potential adverse effects on human health through the food chain. This study aims to determine the concentrations of lead (Pb), zinc (Zn), and copper (Cu) in catfish (Pangasius hypopthalmus) collected from three different locations: floating cages under the Rantau Berangin Bridge, the Danau Bingkuang Bridge, and a cultivation pond in Silam Village. The samples were analyzed using Atomic Absorption Spectrophotometry (AAS) after digestion with a microwave digester. The results showed Pb concentrations in samples JRB 1, JRB 2, JDB 1, JDB 2, KDS 1, and KDS 2 were 479 mg/kg; 16.27 mg/kg; 165.68 mg/kg; 356.21 mg/kg; 99.6 mg/kg; and 336.57 mg/kg, respectively. Zn concentrations were 8.05 mg/kg; 0 mg/kg; 2.45 mg/kg; 1.09 mg/kg; 24.3 mg/kg; and 0.490 mg/kg, while Cu concentrations were 2.84 mg/kg; 2.81 mg/kg; 1.76 mg/kg; 0 mg/kg; 15.65 mg/kg; and 0 mg/kg, respectively. All Pb levels exceeded the maximum limit set by SNI 2729:2021, which is 0.3 mg/kg. Meanwhile, Zn and Cu levels remained within safe limits based on the decree of the Director General of BPOM No. 03725/B/SK/VII/89. Based on these findings, it can be concluded that heavy metal contamination, particularly by Pb, was present in the tested samples, rendering them unsuitable for consumption without further monitoring and testing
SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAN INFUSA KULIT BUAH PEPAYA (Carica papaya L.) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli Deri Islami; Mey Deshafira Sari; Vonny Kurnia Utama
Jurnal 'Aisyiyah Medika Vol 10, No 2: Agustus 2025 Jurnal 'Aisyiyah Medika
Publisher : stikes 'aisyiyah palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36729/jam.v10i2.1417

Abstract

Latar belakang Tanaman pepaya merupakan salah satu jenis tanaman yang dapat digunakan sebagai obat mulai dari daun, buah biji hingga kulitnya. Tujuan : untuk mengetahui apakah ekstrak etanol dan infusa mempunyai aktivitas antibakteri terhadap bakteri gram positif Staphylococcus aureus dan bakteri gram negatif Escherichia coli dan juga mengatahui metabolit sekunder yang terkandung dalam ekstrak etanol dan infusa. Metode :  penelitian ini adalah eksperimental laboratorium dengan cara ekstraksi maserasi dan infusa menggunakan metode difusi sumuran dalam mengamati diameter zona hambat dengan konsentrasi larutan ekstrak dan infusa (80%, 60%, 40%, 20%) serta kloramfenikol sebagai kontrol positif dan akuades sebagai kontrol negatif. Hasil : Penelitian ini diperoleh zona hambat dari ekstrak etanol kulit buah pepaya dengan masing-masing konsentrasi 20%, 40%, 60% dan 80% berturut-turut terhadap bakteri Escherichia coli  yaitu 4,51 mm, 5.23 mm, 7.28 mm, 12.56 mm. Sedangkan untuk zona hambat dari ekstrak etanol terhadap bakteri Staphylococus aureus  yaitu 5,01 mm, 5,30 mm, 5,76 mm, 8,86  mm dan 9.06 mm. Pada infusa kulit buah papaya diperoleh zona hambat pepaya dengan masing-masing konsentrasi 20%, 40%, 60% dan 80% berturut-turut terhadap bakteri Staphylococus aureus yaitu  4,24  mm, 6,83 mm, 8,93 mm, dan 9,06 mm. Sedangkan terhadap bakteri Escherichia coli yaitu  4,57 mm, 5,03 mm, 5,76 mm, dan 7.06 mm. Ekstrak etanol dan infusa kulit buah pepaya mengandung senyawa metabolit sekunder dan memiliki kemampuan dalam menghambat pertumbuhan bakteri. Ekstrak etanol kulit buah pepaya (Carica papaya L.) mengandung alkaloid, flavonoid, tannin dan saponin sedangkan ekstrak infusa mengandung flavonoid, tanin,dan saponin.Saran: untuk penelitian selanjutnya ialah dilakukan peningkatan konsentrasi, bakteri uji serta metode pengujian aktivitas antibakteri lainnya.                                                                                             Kata kunci : Kulit Buah Pepaya, Ekstrak etanol, Infusa, Fitokimia, Antibakteri, Difusi