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All Journal Jurnal Ilmiah Farmasi Jurnal Farmasi Udayana Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) As-syifaa Jurnal Farmasi Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Majalah Farmaseutik Jurnal Ilmiah Manuntung Jurnal Farmasi Indonesia Jurnal Mandala Pharmacon Indonesia Health Sciences and Pharmacy Journal Berkala Ilmiah Mahasiswa Farmasi Jurnal Insan Farmasi Indonesia Jurnal Sains dan Kesehatan

Inaratul Rizkhy Hanifah

Program Studi Farmasi, Fakultas Farmasi, Universitas Setia Budi, Surakarta

Author-ID : 1000173

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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POTENSI TONGKOL JAGUNG (Zea Mays L.) SEBAGAI SUNSCREEN DALAM SEDIAAN HAND BODY LOTION Ekowati, Dewi; Hanifah, Inaratul Rhizky
Jurnal Ilmiah Manuntung Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

The over exposure sunlightis on the skin provides of damage. Skin damage caused the over exposure sunlightis can occur in the short term such as erythema or long term such as premature skin aging and even skin cancer. One way that can be done to minimize the amount of UV that penetrated into the skin is to use sunscreen. Corn cob contain the chemical compounds of phenolic, which suspected to have the protection activity toward the UV B rays. The study aims to make preparations hand body lotion that meet good physical quality of the corn cob extractÂ as a sunscreen.Â Hand made three body lotion formula with extract concentrations of corn cob 10% FI, FII FIII 15% and 20%. Testing the physical properties of the test hand body lotion include viscosity, dispersive power and pH. The effectiveness of a sunscreen is based on a determination of the value of the Sun Protection Factor (SPF) in vitro.Â The third formula has a good physical quality lotion that viscosity 50-1000 dPas, the scatter 5-7 cm, pH 4.5 -7. The effectiveness of sunscreen based on the value of the Sun Protection Factor (SPF), the effectiveness FIII in the category of extra protection is 7.23. SPF value FIÂ FII 5.13 and 5.67 so that FI and FII into the category of moderate protection

FORMULASI SEDIAAN GEL EKSTRAK DAUN SUKUN (Artocarpus altilis) SEBAGAI PENYEMBUHAN LUKA BAKAR PADA KELINCI DENGAN VARIASI KONSENTRASI CARBOPOL 940 SEBAGAI GELLING AGENT Putri Rinda Sari; Supriyadi Supriyadi; Inaratul Rizkhy Hanifah
As-Syifaa Jurnal Farmasi Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v13i2.781

Breadfruit leaves are medicinal plants containing compounds such as flavonoids, saponins, tannins, polyphenols that function in wound healing. This study aimed to determine the variation of the concentration of the gelling agent carbopol 940 on the physical properties of the gel and the duration of the burn wound healing process on gel administration. This study used New Zealand White rabbits. They were divided into five groups. They were positive control (bioskin®), negative control, breadfruit leaf extract gel formula with variations in carbopol concentrations of 0,5%, 1%, and 2%, respectively. Burn percentage was analyzed using SPSS with Kolmogorov- Smirnov test to see normality, Levene test to see homogeneity, if the data is normally distributed and homogeneous, followed by Two Way ANOVA analysis with Post hoc Tukey significance of 0.005. The results of breadfruit leaf extract variations in the gelling agent carbopol 940 affect the physical properties. The increase in the concentration of the gelling agent causes an increase in viscosity, adhesion and decreases dispersion. Variations in the concentration of carbopol effective for healing burns was formula II (breadfruit leaf extract gel formula with variations in carbopol concentrations of 1%). Therefore, the provision of breadfruit leaf extract gel can accelerate the healing process of burns

STUDI LITERATUR RASIONALITAS, DAN POLA SENSITIVITAS TERHADAP ANTIBIOTIK PADA BAKTERI STAPHYLOCOCCUS AUREUS PENYEBAB INFEKSI GANGREN DIABETES MELITUS Aprilia rina wati; ismi rahmawati; Inaratul Rizkhy Hanifah
Berkala Ilmiah Mahasiswa Farmasi Indonesia Vol 8 No 2 (2021): Berkala Ilmiah Mahasiswa Farmasi Indonesia (BIMFI)
Publisher : Ikatan Senat Mahasiswa Farmasi Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48177/bimfi.v8i2.78

Introduction: Diabetic gangrene can be treated with antibiotics. The use of antibiotics must be done rationally. Antibiotic sensitivity patterns know which antibiotics have become resistant. The purpose of this literature study is to determine the relationship between rationality and patterns of antibiotic sensitivity in bacteria that cause gangrene infection. Methods: The research was conducted using a literature study method using journals obtained through journal sites such as search engines Scopus, Google Scholar, ScienceDirect, NCBI, PubMed, Oxford Academics, Cambridge, and Sprinkle link published between 2009-2021, obtained journals as many as 13 journals extracted from 99 existing journals. This literature study was carried out in several stages, namely, formulating problems, collecting data, extracting data, synthesizing data, and compiling a thesis. Result: The results of the literature study rationality of antibiotic use is precise indication, appropriate drug and appropriate patient. Antibiotics that are resistant in several hospitals in Indonesia are ceftriaxone, cotrimoxazole, benzylpenicillin erythromycin, ampicillin, cloramfenicol, cefoperazone, meropenem, cefixime, gentamicin, ceftazidime, ciprofloxacin, streptomycin, lincomycin, and cefotaxime. The mechanism that bacteria have in developing resistance is by enzymatic modification, changes in PBP structure, pump protein production, and changes in antibiotic targets

Analisis Penggunaan Obat di RSUD Kota Yogyakarta Berdasarkan Indikator WHO Inaratul Rizkhy Hanifah
Jurnal Farmasi Indonesia Vol 8 No 1 (2011): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Prescribing the rational drugs is the main orientation of the health care activity that should be increase in quality. The research objectiveâ€™s are to analyze of drug use of patient in RSUD Kota Hospital in the march 2010 period based on WHOâ€™s core indicator and complementary indicator. This research is non-experimental, descriptive design, and prospective data collective. The results obtained in RSUD Kota hospital are appropriate with standards WHO percentage of encounter with an antibiotic prescribed 21.89%, and injection 0%, while inappropriate the standards is the average drug items used per encounter 2.33, percentage of drugs prescribed by generic name 29.29% and percentage of drugs prescribed from formulary 83.84%. Patient care indicators, the average dispensing time was 17.59 minutes (non-compounded) and 25.67 (compounded), where 94.29% of drugs are dispensed and no one adequately labeled. Health facility indicators, there was formulary availability, and availability of key drugs 100%. WHO complementary indicators in RSUD Kota Hospital that average drug cost per encounter 50914.60 IDR, with 28.95% cost spent on antibiotics and injections of 0%.

Pemanfaatan Daun Belimbing Wuluh (Averrhoa bilimbi L) dalam Bentuk Infusa dan Sediaan Celup terhadap Penurunan Berat Badan Inaratul Rizkhy Hanifah; Suhartinah Suhartinah; Opstaria Saptarini
Jurnal Farmasi Indonesia Vol 11 No 2 (2014): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Obesity is excess weight due to the accumulation of fat cells. The adverse effects of obesity are high chances for the spread of degenerative diseases and in terms of aesthetic body look unattractive. This research was aimed to use bilimbi leaves as weight loss with varying doses in two dosage forms, namely infusion and tea bag. The test animals used were female white rats were grouped into: negative control group were given 0.5% CMC; positive control group were given xenicalÂ® a dose of 2.16 mg / 200 g BB rats; and a test group with a dose preparations bilimbi 5.0 mg/200 g BW, 10 mg/200 g BW, and 20 mg/200 g BW. The treatment were given for 30 days and observed weight. At the end of the treatment, animals dissected after anesthetized. Fats contained around abdominal weighed and the results recorded and compared. Results this study were the bilimbi leaves that has been made in the form of infusions and steeping tea bags in which both had effect as a weight loss in female rats wistar strain.

Pengaruh Waktu Fermentasi Teh Kombucha terhadap Penurunan Kadar Glukosa Darah pada Tikus Putih Jantan Galur Wistar dengan Induksi Aloksan Nilam Kristianingtyas; Inaratul Rizkhy Hanifah; Iswandi Iswandi
Jurnal Farmasi Indonesia Vol 12 No 1 (2015): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Diabetes mellitus is a group of metabolism disorders which is characteristic by the blood glucosa levels. Kombucha tea is a fermented product of sweet tea due o activity of yeast and bacteria.The research was aimed to determine the influence of various kombucha fermentation time on the decrease of glucose level in white male rats wistar. The tested animal is were inducted with aloksan and arranged into groups. Each group consisted of 5 white male rats. Group I as negative control was treated by aquadest. Group II, III dan IV were treated by 5,5 ml of 4, 8 and 12 days-fermentation kombucha tea, respectively. Group V, as positive control was treated by glibenclamide at 0,09 mg/200 g BB. The treatments were conducted for two weeks. Each group was observed for glucose levels an the firstand second week. The results were analyzed using one way ANOVA. The result showed that tea kombucha is able to decreaseglucose levels and the 12 days fermented kombucha tea has ability to decrease glucose levels better than 4 and 8 days fermented tea kombucha.

Pengaruh Edukasi Terhadap Pengetahuan Swamedikasi Batuk pada Anak di Kecamatan Wonosari Kabupaten Klaten Jawa Tengah Inaratul Rizkhy Hanifah; Annisa Nur Safitri; Ika Purwidyaningrum
Jurnal Farmasi Indonesia Vol 18 No 2 (2021): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v18i2.1268

Self-medication is one way people treat a symptom of a disease without using a doctor's prescription. Knowledge of correct self-medication is needed to cure coughs without other adverse effects on the sufferer. This study aimed to determine the effect of education through online media on the level of knowledge about cough self-medication for children in Wonosari District, Klaten Regency, Central Java in 2020. This research is a quantitative study with a Quasi-Experimental research method with the technique of Two Group Pre-Test-Post-Test Control Group Design. The population in this study were parents who had children in Wonosari District, Klaten Regency. The sample in this study amounted to 268 people. The data collection tool uses a questionnaire that has been tested for validity and reliability. The results showed that the level of public knowledge when the pre-test was carried out was classified as good (41.04%), moderate (54.48%), poor (4.48%), not good (0%). The provision of education was able to increase the respondent's knowledge as indicated by the results of post-test knowledge, which were classified as good (89.55%), moderate (10.45%), not good (0%), poor (0%). The Wilcoxon test analysis obtained a p-value of 0.000 000 <α value of 0.05, which means that education through online media affects public knowledge about cough self-medication in children.

Gambaran Efek Samping Kontrasepsi Hormonal pada Akseptor Keluarga Berencana di Wilayah Puskesmas X Kabupaten Karanganyar Lucia Vita Inandha Dewi; Eunike Yuvita Purbosari; Inaratul Rizkhy Hanifah
Jurnal Farmasi Indonesia Vol 19 No 2 (2022): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v19i2.1556

Hormonal contraception use in the Family Planning (KB) program can cause side effects that interfere with health, reduce comfort, and cause the program to stop, in several previous studies, weight gain and menstrual disorders have been reported as the most side effects, but it is suspected that there are still side effects. For others that have not been reported, a complete description of the incidence of side effects is needed to consider the selection of a safe and suitable type of contraception for the acceptor. The purpose of the study was to describe the incidence of side effects and the percentage of events based on the type of hormonal contraception. This research is an observational descriptive study involving 327 respondents according to the inclusion criteria, using a questionnaire that has been tested for validity and reliability. The study was conducted on family planning acceptors who are in the working area of Puskesmas X Surakarta. Analysis of the results was carried out univariately by the percentage of the number of adverse events based on the type and type of hormonal family planning used. The results showed that the incidence of side effects in the form of weight gain was 51.8%,, menstrual disorders 38.8%, dizziness 9.1%, nausea 7%, acne 6,1%, and anxiety was 3%. Based on the type of hormonal contraception, the incidence of side effects experienced by acceptors of 3-month injections was 74,3 %, 1-month injections 38,8%, pills 29,9%, and implants was 6,4%.

Hubungan Efek Samping Obat Dengan Length Of Stay (LOS) Pasien Jantung Koroner Di Rumah Sakit “X” Inaratul Rizkhy Hanifah; Asa Puspagiri Setiyasih; Lucia Vita Inandha Dewi
Jurnal Farmasi Indonesia Vol 19 No 2 (2022): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v19i2.1790

Coronary heart disease (CHD) is caused by the narrowing and blockage of blood vessels that carry blood to the heart. CHD is listed as the highest deadly disease by WHO. CHD treatment is carried out long-term and uses a combination of several drugs, so there is a risk of drug side effects. Length of stay (LOS) is one indicator of successful therapy for CHD patients. However, no correlation studies of LOS with the incidence of drug side effects in CHD patients. Therefore, the purpose of the study was to analyze the potential side effects that occur in CHD therapy and to find the relationship with LOS in the "X" Hospital in Surakarta in 2021. This research uses a descriptive observational method by retrospectively taking patient medical record data that match the inclusion criteria. The sample in this study was 81 patients whose results were tabulated and analyzed univariately by describing the results based on the percentage of events. The reference in this study was Meyler's Side Effects of Drugs guidelines and several supporting journals. To find the relationship between the incidence of drug side effects with LOS using SPSS with the chi-square test. The result show that 23 patients (28%) had the incidence of side effects from CHD treatment. Potential side effects arising in patients include muscle pain; weakness; fever; diarrhea; dizziness; constipation; and nausea-vomiting; are 43.48%, 26.09%, 13.04%, 4.35%, 4.35%, 4.35%, 4.35%, respectively. There was no correlation between side effects and LOS (p=0.803; OR=1,132).

Hubungan Interaksi Obat Antibiotik dengan Length of Stay Pasien Pneumonia di Rumah Sakit “X” Ponorogo Bima Nur Priambudi; Samuel Budi Harsono; Inaratul Rizkhy Hanifah
Jurnal Mandala Pharmacon Indonesia Vol. 8 No. 2 (2022): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v8i2.191

Pneumonia adalah penyakit infeksi pada saluran pernapasan bagian bawah yang merupakan penyebab kematian terbanyak di negara-negara berkembang. Prevalensi penyakit pneumonia di Indonesia tahun 2018 sebanyak 1.017.290 jiwa. Pengobatan pneumonia terdiri dari kombinasi antibiotik dan atau terapi suportif yang apabila digunakan secara bersamaan akan berpotensi terjadinya interaksi obat. Penelitian ini bertujuan untuk mengidentifikasi interaksi obat antibiotik dalam pengobatan pasien pneumonia dan menganalisis hubungannya dengan Length of Stay (LOS). Penelitian menggunakan metode cross-sectional dengan rancangan deskriptif dan data diambil secara retrospektif. Analisis data secara deskriptif menggunakan aplikasi Lexicomp Reference, Medscape Reference dan buku Stokley’s Drug Interaction serta analisis dengan metode Chi-Square untuk mengetahui hubungan antara kejadian interaksi obat dengan LOS. Dari total 73 sampel pada periode Januari- Desember tahun 2021 menunjukkan karakteristik pasien didominasi oleh laki- laki sebesar 43 pasien (58,9%), usia diatas 46 tahun sebanyak 56,2%. Penggunaan antibiotik tunggal terbanyak adalah levofloxacin sebesar 50,8% dan antibiotik kombinasi azithromycin+ levofloxacin sebesar 43,5%. Interaksi obat ditemukan pada 54 pasien dengan mekanisme interaksi farmakodinamik, farmakokinetik dan mekanisme tidak diketahui masing-masing sebesar 72,5%, 18,1%, dan 9,3%. Interaksi berdasarkan tingkat keparahan minor, moderate dan major masing-masing sebesar 5,2%, 74,3%, dan 20,5%. Potensi interaksi obat antibiotik tidak memiliki hubungan dengan lama rawat inap pasien (nilai signifikansi >0,05).

Co-Authors Anggriani, Indah Putri Annisa Nur Safitri Aprilia rina wati Asa Puspagiri Setiyasih Bima Nur Priambudi Dewi Ekowati Dewi, Lucia Vita Inandha Dewi, Lucia VIta Inandha Ela Dewi Puspita Sari Emiliya Dwi Agustin Eunike Yuvita Purbosari Harsono, Samuel Budi Ika Purwidyaningrum Ismi Rahmawati Iswandi Iswandi Marisa Stifani Mandala Muhamad Ansory, Hery Nilam Kristianingtyas Opstaria saptarini Pradesthya, Karinda Wirandani Purnomo, Lenis Sufiya Putri Rinda Sari Putri, Clara Prasidya Maharani R A Oetari Rafie Hayunda Marzuk Sasqia Indri Maharani Stevania Windi Suhartinah Suhartinah Supriyadi Wangu, Chelsy Fauziah

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