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Novida Ariani
Universitas Brawijaya
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Journal : Science Midwifery

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The Effect Of Administration Of Acupressure Li4 (Hegu) On The Scale Of Labor Pain In Active Phase 1 In Primipara Mothers In Sehati Kepanjen Maternity Homes Mustika Dewi; Novida Ariani; Anjar Diasti Amna
Science Midwifery Vol 10 No 2 (2022): April: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

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This study aims to determine whether there is an effect of giving LI4 (hegu) acupressure on pain during labor in primiparous mothers in RB Sehati Kepanjen. This study uses the True Eskperimen method (pure experiment) in the form of a post test only control design. The sample used in this study were mothers who were about to give birth entering an opening of 4-10 cm as many as 33 mothers gave birth at the Sehati Kepanjen Maternity Home, where the sampling technique was simple random sampling. The LI4 (Hegu) acupressure method is located in the middle of the first and second metacarpals by applying gentle pressure to the protruding area during labor pain. The scale for measuring labor pain in this study was the Wong-Baker Cat FACES Rating Scale. Data analysis used independent t-test statistical test because the data were normally distributed. The results showed that there was an effect of giving acupressure LI4 (Hegu) on the intensity/scale of maternal pain, especially in the first period at RB Sehati Kepanjen, with T count = 8,383 sig = 0.0001 < 0.05, which means there is a difference in pain where the control group higher (8.59) than the treatment (3.75) statistically stated that there was a significant difference, there was a difference between the control group and the treatment group. The control group (without acupressure LI4) was higher than the treatment group (which was given acupressure LI4).
The Differences Of Matrix Metalloproteinase 9 and Tissue Inhibitor Matrix Metalloproteinase 1 Expression Between Nullipara and Postpartum on Vaginal Wall Of Rattus Norvegicus Novida Ariani
Science Midwifery Vol 9 No 2 (2021): April: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

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The pathophysiology of how the labor process changes the molecular and biochemical changes of the pelvic floor, especially the vaginal wall, causing the female pelvic organ prolapse is not clear. This change is presumed through the mediation of changes in Matrix Metalloproteinase 9 (MMP-9) and Tissue Inhibitor Matrix Metalloproteinase 1 (TIMP-1). Therefore, this study aims to determine changes in MMP-9 and TIMP-1 in postpartum. This research is an observational cohort study on female rats Rattus norvegicus Wistar strain. Replication used was 5 individuals for each nulliparous group, postpartum day-1, day-3 and day-7. Selection of mice by using random allocation. The vaginal wall tissue slides were stained with immunohistochemistry. MMP-9 and TIMP-1 expressions were calculated and analyzed using Analysis of Variance (ANOVA). The results of this study indicate that there is a significant difference (p = 0.007) mean expression of MMP-9 per visual field on the vaginal wall among nullipara (11.2 ± 1.304), postpartum day-1 (13.2 ± 2,387), day- 3 (12.6 ± 2.191), and day-7 (8.0 ± 2,550). There was an increasing trend of MMP-9 expression on the 1st day postpartum, then MMP-9 gradually decreased until postpartum on the 7th day. The results in this study also showed that there was a significant difference (p = 0.028) in the mean of TIMP-1 expression on the vaginal wall between nulliparous rats (11.6 ± 1.342), postpartum day -1 (15.4 ± 3.130), day -3 (13.2 ± 2.683), and day-7 (10.8 ± 1.483). There was increased expression of TIMP-1 day-1 postpartum than nullipara, then decreased gradually until the 7th day postpartum.
Co-Authors Adhinda Resta Camelia Anjar Diasti Amna Asmika Asmika Catur Wilujeng Danik Agustin, Danik Hanesty, Avila Hikmawan Wahyu Sulistomo HUSNUL KHOTIMAH Ida Widiawati, Ida Intan Zahiroh Irmawati, Oktin Irwandi Kalsumy, Umi Lubna Maimunah Meyana Marbun Mustika Dewi Nikmatul Khasanah Ningrum Paramita Sari Nurdiana Zaenal Permata, Dear Ayu Putri Hainun Sasabela Rismaina Putri Sonia Lahita Septianingrum Syahana Aini Tatit Nurseta Yolanda Eldamayanti