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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Journal of Issues in Midwifery Jurnal Aisyah : Jurnal Ilmu Kesehatan Science Midwifery Jurnal EduHealth Jurnal Multidisiplin Madani (MUDIMA) Formosa Journal of Applied Sciences (FJAS) Formosa Journal of Sustainable Research (FJSR) Jurnal Indonesia Sosial Sains International Journal of Integrative Sciences Jurnal Kesehatan Metro Sai Wawai Oshada Jurnal Penelitian Sains dan Kesehatan Avicenna Aspiration of Health Journal
Novida Ariani
Universitas Brawijaya
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Hubungan Faktor Obstetri dan Sosio Ekonomi dengan Outcome Maternal Covid-19 pada Pandemi Covid-19 Gelombang Kedua di RS Rujukan Pasuruan, Indonesia Novida Ariani; Catur Wilujeng; Syahana Aini
Jurnal Multidisiplin Madani Vol. 2 No. 5 (2022): May, 2022
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/mudima.v2i5.391

Abstract

The second wave of the Covid-19 pandemic in Indonesia has an impact on increasing maternal morbidity and mortality. Research is needed to determine maternal characteristics and their relationship to outcomes. The study design is a cross sectional at Bangil Hospital, in the second wave of covid-19 in July to September 2021. Maternal outcomes with poor results if they require treatment to fulfill oxygen (nasal cannula, hnfc or ventilator), are treated in the Intensive Care Unit (ICU), there are complications or maternal death occurs. Based on the results of the study, it was found that 26 (28.3%) mothers had good outcomes, while 66 (71.3%) had poor outcomes. Maternals requiring hnfc 6 (6.5%), were admitted to the ICU as many as 6 (6.5%). There was a significant relationship between age (p=0.036) and parity (p=0.009) with maternal outcome
Kurkumin Menghambat Ekspresi Matrix Metalloproteinse-9 pada Endometrium Fase Luteal Novida Ariani
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (696.226 KB) | DOI: 10.36418/syntax-literate.v6i3.2386

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian kurkumin sebagai agen antifertilitas melalui hambatan ekspresi MMP-9 endometrium. Jenis penelitian ini adalah experimental post-test control randomized group design. Dua puluh ekor tikus Rattus norvegius strain Wistar betina dibagi mejadi empat kelompok : kelompok kontrol, ED50, 2 x ED50 dan kelompok Kurkumin 4 x ED50. Tikus diinduksi ovulasi dengan pemberian PMSG 5 IU i.p umur 28 hari dan & hCG 5 IU i.p umur 30 hari hingga memasuki fase luteal. Umur 31 hari dievaluasi ekspresi MMP-9 pada masa luteal pada sediaan endometrium dengan pewarnaan imunohistokimia. Tampak ada tren penurunan yang signifikan mean ekspresi MMP-9 pada endometrium tikus yang diberi kurkumin (p=0.000< ). Mean ekspresi MMP-9 endometrium kelompok kontrol (71,8 ± 3,7), kelompok Kurkumin ED50 (57,2 ± 4,1), kelompok Kurkumin 2 x ED50 (34,4 ± 3,4) dan kelompok Kurkumin 4 x ED50 (20,6 ± 1,9). Pemberian kurkumin menurunkan kadar MMP-9 endometrium pada tikus betina hingga mencapai puncaknya pada dosis 4 x ED50. Kesimpulan dari penelitian ini adalah Kurkumin menghambat ekspresi MMP-9 yang dibutuhkan untuk implantasi zygote pada endometrium fase luteal.
The Effect Of Administration Of Acupressure Li4 (Hegu) On The Scale Of Labor Pain In Active Phase 1 In Primipara Mothers In Sehati Kepanjen Maternity Homes Mustika Dewi; Novida Ariani; Anjar Diasti Amna
Science Midwifery Vol 10 No 2 (2022): April: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

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Abstract

This study aims to determine whether there is an effect of giving LI4 (hegu) acupressure on pain during labor in primiparous mothers in RB Sehati Kepanjen. This study uses the True Eskperimen method (pure experiment) in the form of a post test only control design. The sample used in this study were mothers who were about to give birth entering an opening of 4-10 cm as many as 33 mothers gave birth at the Sehati Kepanjen Maternity Home, where the sampling technique was simple random sampling. The LI4 (Hegu) acupressure method is located in the middle of the first and second metacarpals by applying gentle pressure to the protruding area during labor pain. The scale for measuring labor pain in this study was the Wong-Baker Cat FACES Rating Scale. Data analysis used independent t-test statistical test because the data were normally distributed. The results showed that there was an effect of giving acupressure LI4 (Hegu) on the intensity/scale of maternal pain, especially in the first period at RB Sehati Kepanjen, with T count = 8,383 sig = 0.0001 < 0.05, which means there is a difference in pain where the control group higher (8.59) than the treatment (3.75) statistically stated that there was a significant difference, there was a difference between the control group and the treatment group. The control group (without acupressure LI4) was higher than the treatment group (which was given acupressure LI4).
The Differences Of Matrix Metalloproteinase 9 and Tissue Inhibitor Matrix Metalloproteinase 1 Expression Between Nullipara and Postpartum on Vaginal Wall Of Rattus Norvegicus Novida Ariani
Science Midwifery Vol 9 No 2 (2021): April: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

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Abstract

The pathophysiology of how the labor process changes the molecular and biochemical changes of the pelvic floor, especially the vaginal wall, causing the female pelvic organ prolapse is not clear. This change is presumed through the mediation of changes in Matrix Metalloproteinase 9 (MMP-9) and Tissue Inhibitor Matrix Metalloproteinase 1 (TIMP-1). Therefore, this study aims to determine changes in MMP-9 and TIMP-1 in postpartum. This research is an observational cohort study on female rats Rattus norvegicus Wistar strain. Replication used was 5 individuals for each nulliparous group, postpartum day-1, day-3 and day-7. Selection of mice by using random allocation. The vaginal wall tissue slides were stained with immunohistochemistry. MMP-9 and TIMP-1 expressions were calculated and analyzed using Analysis of Variance (ANOVA). The results of this study indicate that there is a significant difference (p = 0.007) mean expression of MMP-9 per visual field on the vaginal wall among nullipara (11.2 ± 1.304), postpartum day-1 (13.2 ± 2,387), day- 3 (12.6 ± 2.191), and day-7 (8.0 ± 2,550). There was an increasing trend of MMP-9 expression on the 1st day postpartum, then MMP-9 gradually decreased until postpartum on the 7th day. The results in this study also showed that there was a significant difference (p = 0.028) in the mean of TIMP-1 expression on the vaginal wall between nulliparous rats (11.6 ± 1.342), postpartum day -1 (15.4 ± 3.130), day -3 (13.2 ± 2.683), and day-7 (10.8 ± 1.483). There was increased expression of TIMP-1 day-1 postpartum than nullipara, then decreased gradually until the 7th day postpartum.
Pengaruh Pemberian Jus Buah Sirsak (Annona Muricata Linn) Terhadap Kadar Malondialdehyde (MDA) Plasenta Tikus Putih Strain Wistar (Rattus novergicus) Bunting dengan Paparan Asap Rokok) Nurdiana Zaenal; Novida Ariani; Intan Zahiroh
Jurnal Multidisiplin Madani Vol. 2 No. 7 (2022): July 2022
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/mudima.v2i7.607

Abstract

Cigarettes contain many toxic free radicals and reactive oxygen species (ROS) which can trigger cell membrane lipids, proteins, enzymes, and DNA to undergo oxidative damage. The amount of ROS (reactive oxygen species) during pregnancy can increase if pregnant women are exposed to cigarette smoke which are toxic due to the risk of oxidative stress so as to form Malondialdehyde (MDA) compounds caused by lipid peroxidation. Lipid peroxidation and increased levels of MDA can cause damage to cell membranes, one of which is the placental endothelial cell membrane. The content of vitamin C and sufficient polyphenols in soursop has the potential as a source of antioxidants that can inhibit or slow down the formation of free radicals and ROS. Objective: To determine the benefits or effect of giving soursop fruit juice (Annona muricata Linn) on the placental MDA levels of pregnant rats with wistar strain (Rattus norvegicus) exposed to cigarette smoke. Methods: A true experimental laboratory with a randomized posttest-only control group design. Different doses of exposure to cigarette smoke and soursop juice were selected at random and divided into 3 treatment groups and 2 control groups. Giving soursop fruit juice was carried out on the first day until the nineteenth day of pregnancy, while cigarette smoke was exposed on the seventh day until the nineteenth day of pregnancy. Results: The significance value calculated by the Kruskal-Wallis test was 0.350 (p>0.05), which showed that there was no significant effect on the MDA value of the placenta of pregnant rats given soursop fruit juice and exposed to cigarette smoke. Conclusion: Soursop fruit juice with a dose of 0.5gr/200gr BW/day can prevent the increase in MDA levels of pregnant rat placenta exposed to cigarette smoke.
Pengaruh Ekstrak Etanol Daun Inggu (Ruta angustifolia) terhadap Tebal Otot Polos Tuba Fallopi Tikus Strain Wistar Betina Novida Ariani; Hikmawan Wahyu Sulistomo; Yolanda Eldamayanti
Journal of Issues in Midwifery Vol. 6 No. 3 (2022)
Publisher : Journal of Issues in Midwifery

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.JOIM.2022.006.03.3

Abstract

ABSTRAK: Latar Belakang : Tingginya penghentian pemakaian kontrasepsi hormonal disebabkan oleh efek samping yang dialami akseptor KB menjadi latar belakang penelitian penggunaan tanaman herbal sebagai antifertilitas pengganti KB hormonal yang memiliki efek minimal. Daun tanaman inggu (Ruta angsutifolia) memiliki kandungan senyawa yang diduga mengganggu kerja hormonal sehingga dapat menjadi antifertilitas seperti saponin, tanin, chalepin dan chalepensin. Tujuan : Untuk menguji pengaruh ekstrak etanol daun inggu terhadap tebal otot polos tuba fallopi tikus putih. Metode : Penelitian experimental menggunakan randomized post-test only controlled group sebagi rancangannya dilakukan dari Februari hingga April 2022. Hewan coba (tikus putih Strain Wistar) dibagi menjadi 4 kelompok dengan perlakuan dosis (0; 0,4; 0,8; dan 1,2 g/kg BB). Pengukuran tebal otot polos tuba fallopi pada slide histopatologi memakai mikroskop jenis Olympus CX23 dan aplikasi ImageJ. Hasil : tebal otot polos organ tuba fallopi tikus menurun berbanding terbalik dengan dosis ekstrak etanol daun inggu yang meningkat dengan hasil signifikan secara statistik (p= 0,046). Kesimpulan : ketebalan otot polos organ tuba fallopi menunurun akibat ekstrak etanol daun inggu yang diberikan dengan dosis optimal 1,2 g/kg BB. Kata Kunci: daun inggu, tebal otot polos tuba fallopi, kontrasepsi
Hubungan Kadar Cuprum dan Malondialdehyde Pada Kehamilan Novida Ariani
Jurnal Indonesia Sosial Sains Vol. 2 No. 03 (2021): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (544.539 KB) | DOI: 10.59141/jiss.v2i03.212

Abstract

Tembaga (Cu) memiliki hubungan yang kuat dengan stres oksidatif. Selain karakteristik prooksidannya, Cu memiliki peran potensial untuk menginduksi antioksidan endogen. Namun peran bersihnya masih belum jelas. Penting untuk diketahui peran bersih Cu terutama pada kehamilan trimester kedua dan ketiga yang rentan terhadap keadaan stres oksidatif. Oleh karena itu tujuan dari penelitian ini adalah untuk mengetahui hubungan antara kadar Cu dan Malondialdehida plasma pada kehamilan trimester II dan III. Metode yang digunakan dalam penelitian ini adalah observasional analitik dengan desain cross sectional. Subjek terdiri dari dua kelompok yaitu kehamilan trimester kedua dan ketiga. Masing-masing kelompok ditentukan konsentrasi plasma Cu dan MDA menggunakan SSA (Spektrofotometri Serapan Atom) dan Spektrofluorometer. Hasil investigasi menunjukkan bahwa konsentrasi Cu belum berkorelasi dengan konsentrasi MDA di trimester kedua dan ketiga karena ada faktor lain yang menentukan plasma MDA lebih kuat dari Cu (r2 2nd trimester = 0,132; r2 3rd trimester = 0,043). Kadar Cu trimester ketiga lebih tinggi daripada trimester kedua karena kehamilan meningkatkan penyerapan dan retensi Cu. Kadar MDA trimester ketiga lebih rendah dari trimester kedua karena pertahanan antioksidan endogen. Dalam kehamilan, Cu cenderung menurunkan stress osidatif. Jadi, meskipun Cu memiliki sifat prooksidan atau menimbulkan oksidasi, namun karena mampu menginduksi antioksidan endogen, Cu berperan bersih menurunkan keadaan stres oksidatif.
The Effect Of Giving Pegagan (Centella Asiatica) Ethanol Extract On Incised Wound Healing In White Rats (Rattus Norvegicus) Novida Ariani; Umi Kalsum; Adhinda Resta Camelia
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.7 KB)

Abstract

This study aims to determine the effect of giving Centella asiatica on incised wound healing through the treatment of Centella asiatica on white rats (Rattus norvegicus). This study uses Experimental method in the form of a post-test only group design to determine the effect of Centella asiatica ethanol extract on the healing time of incised wound in white rats (Rattus norvogicus). The sample used in this study was 20 white rats divided into five treatment groups. Data analysis used quantitative analysis with helped of SPSS 29 software. The data test consisted of normality, homogeneity, and one way ANOVA test. The result showed 10% Povidone iodine, vaseline, 10% ointment of Centella asiatica ethanol extract, 15% ointment of Centella asiatica ethanol extract, and 25% ointment of Centella asiatica ethanol extract had the same effect on incised wound healing in white rats (Rattus norvogicus). Intervention with 10% Povidone iodine had average healing time of 12,75 days; intervention with 10% ointment of Centella asiatica ethanol extract had average healing time of 10 days; intervention with 15% ointment of Centella asiatica ethanol extract had average healing time of 8,75 days; and intervention with 25% ethanol extract Centella asiatica had average healing time of 12,75 days. The normaly test shows that the entire group has a significant value of p>0,05, so it says that the data is normally distributed. The homogeneity test shows an overall significance of p>0,05, so the data is nuanced and homogeneous. The ANOVA test showed a significance of p = 0,152, so the value of p >0,05, meant that there was so significant difference between groups. This study proved that the application of Centella asiatica ethanol extract ointment can be used as an alternative in the treatment of incised wound, such as post-section caesarean wound care.
Factors Associated with Postpartum Visits in the Work Area of the Polanharjo Health Center, Klaten, Indonesia Novida Ariani; Rismaina Putri; Sonia Lahita Septianingrum
Formosa Journal of Applied Sciences Vol. 2 No. 7 (2023): July 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjas.v2i7.5118

Abstract

This research design uses cross sectional. A sample of 33 postpartum mothers in the working area of the Polanharjo Klaten Health Center. Of the 33 respondents, there were 20 respondents (60.6%) with incomplete postpartum visits and 13 respondents (39.4%) with complete postpartum visits. The highest level of education is junior high school with 16 respondents (48.5%), 19 respondents (57.6%) live near health care facilities, 23 respondents (69.7%) have low income, 21 respondents (63.6%) are supported family. Based on the Chi-Square Analysis, the p value of education level = 0.015, p distance from home to health facility = 0.011, p family income = 0.133, and p family support = 0.043. It can be concluded that there is a significant relationship between education level, distance from home to health facilities, family support and the number of postpartum visits.
The Effect of Yellow Pumpkin Pudding (Cucurbita Moschata) on Sleep Quality in Postpartum Mothers in the Working Area of the Dinoyo Health Center, Malang Novida Ariani; Ningrum Paramita Sari; Putri Hainun Sasabela
Formosa Journal of Sustainable Research Vol. 2 No. 7 (2023): July 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjsr.v2i7.5117

Abstract

Sleep is a biological process experienced by humans, as well as the most basic human needs. Proper rest and sleep are just as important for health as nutrition and adequate exercise. Sleep disorders can be overcome with non-pharmacological measures to prevent the risk of anxiety that occurs in postpartum mothers. Pumpkin containing L-tryptophan, zinc, and magnesium. to determine the effect of pumpkin pudding (Curcubita moschata) on sleep quality for postpartum women in the Working Area of Puskesmas Dinoyo, Malang. Methods: The research design is quasi experiment using non-equivalent control group design. Analysis by Paired t-test. This study used a sample of 32 postpartum mothers who matched the inclusion and exclusion criteria in the Working Area of Puskesmas Dinoyo, Malang. The participant received pumpkin pudding or milk pudding every day for a week. : showed that there was an effect of pumpkin pudding (Curcubita moschata) on sleep quality for postpartum mothers shown that p value = 0.000  (p-value <0.05). There is an effect of pumpkin pudding (Curcubita moschata) on sleep quality for postpartum women in the Working Area of Puskesmas Dinoyo, Malang
Co-Authors Adhinda Resta Camelia Anjar Diasti Amna Asmika Asmika Catur Wilujeng Danik Agustin, Danik Hanesty, Avila Hikmawan Wahyu Sulistomo HUSNUL KHOTIMAH Ida Widiawati, Ida Intan Zahiroh Irmawati, Oktin Irwandi Kalsumy, Umi Lubna Maimunah Meyana Marbun Mustika Dewi Nikmatul Khasanah Ningrum Paramita Sari Nurdiana Zaenal Permata, Dear Ayu Putri Hainun Sasabela Rismaina Putri Sonia Lahita Septianingrum Syahana Aini Tatit Nurseta Yolanda Eldamayanti