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Journal : Jurnal Farmasi Indonesia

Ketidaksesuaian Dosis dan Interval Pemberian Antibiotik pada Lansia di Bangsal Penyakit Dalam RSUD dr Moewardi Solo serta Gambaran Timbulnya Efek Samping yang Merugikan Rita Septiana; Risma Sakti Pambudi
Jurnal Farmasi Indonesia Vol 16 No 2 (2019): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (500.354 KB) | DOI: 10.31001/jfi.v16i2.624

Abstract

Aging causes a decrease in renal blood flow velocity and clearance values ​​related to renal filtration function. A decrease in kidney filtration function results in a decrease in the ability of drug elimination so that the drug and its metabolites tend to accumulate in the blood. The dose of certain antibiotics must be adjusted to the patient's kidney function. Clinical estimates of kidney filtration function are expressed in terms of creatinine clearance (CrCl). This study aims to determine the percentage of suitability of the dose and interval of antibiotic administration with the CrCl value of elderly patients and to see description of the side effects arising from the administration of antibiotics. This research was observational with data retrospective retrieval of medical records. The subjects of the study were elderly patients who were hospitalized in the ward ward in dr. Moewardi Solo Hospital in the period January - May 2019 , ≥ 60 years aged with a diagnosis of Pneumonia, Urinary Tract Infection (UTI), Cellulitis and sepsis with complete medical record data. The antibiotics evaluated are all antibiotics given to the patient while being treated. The results showed the suitability of the dose and interval of antibiotic administration with the CrCl value of elderly patients hospitalized in the disease ward in RSUD Dr. Moewardi Solo for the period January-May 2019 was 63.35%, the incidence of side effects arising from the administration of antibiotics was nausea and vomiting (10 patients ) and diarrhea (4 patients).
Pengaruh Corona Virus Disease terhadap Penjualan Produk Suplemen Kesehatan Khotimatul Khusna; Rita Septiana; Ghani Nurfiana Fadma Sari; Isma Rosida
Jurnal Farmasi Indonesia Vol 18 No 1 (2021): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v18i1.937

Abstract

Corona Virus Disease-19 (COVID-19) has been declared a pandemic by the World Health Organization (WHO) on March 11, 2020, previously on March 2, 2020 Indonesia has reported 2 confirmed cases of COVID-19. Immunomodulators that can increase the body's resistance to the COVID-19 virus by stimulating the immune system. The purpose of this study was to determine the effect of COVID-19 on the sale of health supplement products in a pharmacy in Surakarta.This research is an analytical observational research. Data was collected from sales records at pharmacies in the 3 months before the COVID-19 pandemic and 3 months at the beginning of the COVID-19 pandemic. Data analysis using statistical tests.Sales of health supplement products for 6 months were 17843 pcs. There were 4773 health supplement products sold before the pandemic, while 13070 pcs were sold during the pandemic. The results of the normality test showed that the data were not normally distributed. The Wilcoxon test results show that the significant value is 0.028 (<0.05), meaning that there is a difference in sales before and after the determination of the pandemic. The conclusion of this study is that COVID-19 has an effect on the sale of health supplement products in a pharmacy in Surakarta.